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The map label for this gene is sdaA [H]

Identifier: 150396258

GI number: 150396258

Start: 1107368

End: 1108768

Strand: Direct

Name: sdaA [H]

Synonym: Smed_1037

Alternate gene names: 150396258

Gene position: 1107368-1108768 (Clockwise)

Preceding gene: 150396255

Following gene: 150396259

Centisome position: 29.28

GC content: 61.1

Gene sequence:

>1401_bases
ATGTTTCTTTCCGTCTTCGACGTATTCAAGATCGGTATCGGCCCGTCGAGCTCACATACGATGGGGCCGATGTCGGCGGC
GAACAGGTTTCTCGATCTTATTCTTTCGGACGAATGGCCGCGGCCCTCCAACGCAGCTGTTGCCGCTATCCAGGTCAGCC
TTCATGGTTCGCTGGCGCATACGGGAATCGGCCATGGATCGGGCAGGGCGGTTATTCTCGGCCTGATGGGCGAACGCCCC
GATCTCGTGGATCCGGACAAGATGGACGAGGTAATCGAGGAGGTGGAGCGCACAGGGCGTATCACGCCGCCTGGACATCC
TTCCTATGCATTCCAGCCTAAGGCGGATCTGGTTTTCGACAAGAAGATGGCGCTGCCTGGCCATGCCAACGGCATGTCCT
TCTCCGCCTTCGACCGCGACGGCCGGCTGCTTCTGAAACGCATCTACTATTCGATCGGTGGCGGCTTCGTCGTTACTGAT
ACGGAGCTCGGCGCGATGAGAGCTCAGAAGAACAAGACGGCCGGCGTCAAAGTGCCGTATCCCTTTGCCACCGCACAGCA
GATGCTCGACATGGCCGCCCGTTCCGGAATGAGCATCGCTCAGATGAAACGGGCCAACGAAGAATGCAGCATGTCGAGGC
AGGAGCTCGACAACGGGCTCGACCGCATTTGGGCGGCAATGAACAGTTGCATCGACCGCGGGCTCAGCCAGGACGGCATC
ATGCCGGGCGGGCTAAAGGTTCGCCGCCGCGCCAGGGCAATCCACGACAAGCTCCAGGAGGAGTGGCGTTCCAACAAGGT
TAATCCTCTACTCGCCAACGATTGGCTGAGCGTCTATGCGATGGCGGTCAACGAGGAGAATGCCGCCGGTGGCCGGGTGG
TGACGTCGCCTACGAACGGGGCGGCAGGTGTCGTCCCGGCGACGATCCGCTACTATCTTCATTTTCACGAGGATGCCGAC
CAGGACGGTATCCGCGACTATCTGCTGACTGCCGCGGCGGTTGGCGGTATCATAAAGCACAACGCCTCTATTTCCGGGGC
GGAGGTCGGCTGTCAGGGCGAAGTTGGATCCGCGTCGGCGATGGCCGCCGCGGGCCTTGCAGCGGTGATGGGCGGAACGC
CGGAGCAGATCGAGAATGCGGCCGAAATCGCCCTCGAACACCACCTTGGAATGACCTGCGATCCGGTCGCAGGCCTCGTC
CAGGTGCCTTGCATCGAGCGTAACGCCCTTGGTGCCGTCAAGGCGGTCACGGCCGCCTCGCTCGCCCTTAAGGGCGATGG
CAAGCATTTCGTGCCGCTCGATGCCTGTATCGAGACGATGCGCCAAACCGGCGTGGACATGAACGAAAAGTACAAGGAAA
CATCGACGGGCGGTCTCGCGGTCAACGTCGTGGAGTGTTAA

Upstream 100 bases:

>100_bases
ACGCCGTCCCAGAAGCAAACCGGTCGGCTCGGTTCCATCATCGACGCAGGCGTGAAGGTGCTCGGCATCGGCTCCTCGTC
AGATTCTAGGCAGGCAGTTC

Downstream 100 bases:

>100_bases
CGCGAATGCGGACCGAGAGCCGCGTAATTGTTTTCCTCCTCGCGCTGCTAATCCGGAGCCGGCGGGCTGTGGACGAAGCT
GTCGGGGGCTTGACCGATAC

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MFLSVFDVFKIGIGPSSSHTMGPMSAANRFLDLILSDEWPRPSNAAVAAIQVSLHGSLAHTGIGHGSGRAVILGLMGERP
DLVDPDKMDEVIEEVERTGRITPPGHPSYAFQPKADLVFDKKMALPGHANGMSFSAFDRDGRLLLKRIYYSIGGGFVVTD
TELGAMRAQKNKTAGVKVPYPFATAQQMLDMAARSGMSIAQMKRANEECSMSRQELDNGLDRIWAAMNSCIDRGLSQDGI
MPGGLKVRRRARAIHDKLQEEWRSNKVNPLLANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVVPATIRYYLHFHEDAD
QDGIRDYLLTAAAVGGIIKHNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLALKGDGKHFVPLDACIETMRQTGVDMNEKYKETSTGGLAVNVVEC

Sequences:

>Translated_466_residues
MFLSVFDVFKIGIGPSSSHTMGPMSAANRFLDLILSDEWPRPSNAAVAAIQVSLHGSLAHTGIGHGSGRAVILGLMGERP
DLVDPDKMDEVIEEVERTGRITPPGHPSYAFQPKADLVFDKKMALPGHANGMSFSAFDRDGRLLLKRIYYSIGGGFVVTD
TELGAMRAQKNKTAGVKVPYPFATAQQMLDMAARSGMSIAQMKRANEECSMSRQELDNGLDRIWAAMNSCIDRGLSQDGI
MPGGLKVRRRARAIHDKLQEEWRSNKVNPLLANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVVPATIRYYLHFHEDAD
QDGIRDYLLTAAAVGGIIKHNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLALKGDGKHFVPLDACIETMRQTGVDMNEKYKETSTGGLAVNVVEC
>Mature_466_residues
MFLSVFDVFKIGIGPSSSHTMGPMSAANRFLDLILSDEWPRPSNAAVAAIQVSLHGSLAHTGIGHGSGRAVILGLMGERP
DLVDPDKMDEVIEEVERTGRITPPGHPSYAFQPKADLVFDKKMALPGHANGMSFSAFDRDGRLLLKRIYYSIGGGFVVTD
TELGAMRAQKNKTAGVKVPYPFATAQQMLDMAARSGMSIAQMKRANEECSMSRQELDNGLDRIWAAMNSCIDRGLSQDGI
MPGGLKVRRRARAIHDKLQEEWRSNKVNPLLANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVVPATIRYYLHFHEDAD
QDGIRDYLLTAAAVGGIIKHNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLALKGDGKHFVPLDACIETMRQTGVDMNEKYKETSTGGLAVNVVEC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=465, Percent_Identity=47.9569892473118, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1789161, Length=466, Percent_Identity=46.5665236051502, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1788116, Length=463, Percent_Identity=47.0842332613391, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49587; Mature: 49587

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDVFKIGIGPSSSHTMGPMSAANRFLDLILSDEWPRPSNAAVAAIQVSLHGSLAH
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHH
TGIGHGSGRAVILGLMGERPDLVDPDKMDEVIEEVERTGRITPPGHPSYAFQPKADLVFD
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
KKMALPGHANGMSFSAFDRDGRLLLKRIYYSIGGGFVVTDTELGAMRAQKNKTAGVKVPY
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCC
PFATAQQMLDMAARSGMSIAQMKRANEECSMSRQELDNGLDRIWAAMNSCIDRGLSQDGI
CHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPGGLKVRRRARAIHDKLQEEWRSNKVNPLLANDWLSVYAMAVNEENAAGGRVVTSPTNG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCC
AAGVVPATIRYYLHFHEDADQDGIRDYLLTAAAVGGIIKHNASISGAEVGCQGEVGSASA
CCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
MAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAAS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LALKGDGKHFVPLDACIETMRQTGVDMNEKYKETSTGGLAVNVVEC
EEEECCCCEECCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MFLSVFDVFKIGIGPSSSHTMGPMSAANRFLDLILSDEWPRPSNAAVAAIQVSLHGSLAH
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHH
TGIGHGSGRAVILGLMGERPDLVDPDKMDEVIEEVERTGRITPPGHPSYAFQPKADLVFD
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
KKMALPGHANGMSFSAFDRDGRLLLKRIYYSIGGGFVVTDTELGAMRAQKNKTAGVKVPY
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCC
PFATAQQMLDMAARSGMSIAQMKRANEECSMSRQELDNGLDRIWAAMNSCIDRGLSQDGI
CHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPGGLKVRRRARAIHDKLQEEWRSNKVNPLLANDWLSVYAMAVNEENAAGGRVVTSPTNG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCC
AAGVVPATIRYYLHFHEDADQDGIRDYLLTAAAVGGIIKHNASISGAEVGCQGEVGSASA
CCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
MAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAAS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LALKGDGKHFVPLDACIETMRQTGVDMNEKYKETSTGGLAVNVVEC
EEEECCCCEECCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]