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The map label for this gene is aidB [C]

Identifier: 150395712

GI number: 150395712

Start: 528649

End: 530430

Strand: Direct

Name: aidB [C]

Synonym: Smed_0487

Alternate gene names: 150395712

Gene position: 528649-530430 (Clockwise)

Preceding gene: 150395711

Following gene: 150395713

Centisome position: 13.98

GC content: 64.2

Gene sequence:

>1782_bases
ATGTACAAGGCACCGGTCGACGAGATCGCATTCACCCTGAAGCATGTGGCCGGCTTGGCCGAGGCAATCGATCGCGGCGC
ATTCGGCGAGCTGGGCGAGGACCTGGTGGATGCGATCCTTGGCGAGGCCGGGCGCTTCGCCTCGGAAGAGGTGGCGCCGC
TTGGCGACGCAGGTGACCGGCGAGGGGCGCGGCTCGTCGGCGGCACAGTCGAGACGCCGGAGGGCTGGCGGGACCTCTAC
CACAACTGGATTGCCGGCGGCTGGAACGGCCTGACGGCGCCGGAAGCCTATGGCGGGCAGAACCTGCCGCATATGCTGCA
CGTTGCCGCCATGGAAATGTGGAACAGCGGCTCGATGGCTTTCGCGCTTGCGCCAACACTGACAATGGGTGCCATCGAAG
CGCTCGAGAAGCACGGCACCGAGGTTCTAAAGTCGGTCTTCCTGCCGAAAATGGTTTCGGGGGAGTGGATGGGCACGATG
AACCTGACAGAGCCACATGCCGGCTCCGATCTCGGGGTGCTCAAGACCCGCGCCGAGCGCTGCGACGACGGCACCTACCG
CATTTTCGGGCAGAAGATCTTCATTACCTGGGGCGAGCACGACTTCACCGACAATATCGTCCATCTGGTGCTTGCGCGGC
TGCCGGATGCGCCGCCGGGAACCAAGGGCATTTCACTGTTTCTCGTGCCGAAATTCCTCGTCAATGGCGACGGCTCGCTC
GGCGCCCGCAACGATCTCTTCTGCCATTCGCTTGAGCACAAGCTCGGCATCCACGGATCGCCGACCTGCACCATGATCTA
CGGCGACGGCCGGTTTGGCGCCGAAAAAGGTGCTGTCGGTTACCTCGTGGGGGAAGAAAACCGGGGCCTCGCCTGTATGT
TCACGATGATGAACAATGCACGGCTTGCAGTCGGCATGCAGGGCGTGGCGATCGCGGAGGCTGCGACCCAGAAGGCCATC
GCCTACGCCAAGGAGCGCAGGCAGGGCCGTGCGCCGGGATGGAGCGGCGAGGGCATGAGCCCGATCATCGAACATCCGGA
CGTCGCCCGCATGCTGCTGACGATGAAGGCGCTGACTCAAGGTTCGCGCGCCATCGCCTATGCCTGCGCCCACGCTGTCG
ACATGGCCCATTTTGCGGAAGGCGAGGAAGCGCGCCACTGGCAGGAGCGTTCGAGTTTGCTGACGCCGATCGCCAAGTCC
TTTGCCACCGATGCCGGCGTTGACGTCGCCTCCTTGGGGGTTCAGGTTCATGGCGGTATGGGCTTCATCGAGGAGACCGG
GGCCGCGCGCTATCTCCGCGACGCCCGCATCGCGCCAATCTATGAAGGGACCAACGGGATCCAGGCAATCGACCTGGTCA
CCCGCAAGCTGCCGCTTTCCGATGGCGCGCATGTGCGCGGCTTCATTGCCGAACTCCGGGAGGTTACAGCTGCCGTTGCC
GCGTCGAACAGAAAAGGGTTCGGCGAAACGGCGGCGCGCCTGGATGCGGCGATTGCGGATCTCGAAGGGGCGACCGCGTG
GCTGCTTTCGGCAATTCGAGACGGAAAGCTTGCCGAGGCGCTCGCCGGTGCGACCGCTTATCAGCGCCTGTTCGGTCTCG
TGCTGACCGCGATCTATCTCGCCAAGGGCGGGCTTGCCGAAGCCGGTGACGGAAAGCAGGAACAGCGCATTGCGCTTTGC
CGCTTCGCGGCGGAAAACCTGGTTTCGGAGACGAGTGCACTCGAGGACCGCGTAACCAACGGCGCGGAAAGTCTCGCCGC
TGCCCGTTCCATACTCGATTGA

Upstream 100 bases:

>100_bases
GGAAAGGGTGCGGTTCCGTGCCGCATGCCGTTCAGACTTTTGAGGCGATCACGTTTGTCGGCCACGCGGACTGCACCACC
GTGATCCAAGGAGGATCGTC

Downstream 100 bases:

>100_bases
GGGAAGATCCATGACCGACCATGTGCTCGTTGAACGGCCGGAAGCCTATCCCGGAGTCCAGCTCATCCGCTTCAACCGGC
CGGAGAAGAAGAACGCCATC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MYKAPVDEIAFTLKHVAGLAEAIDRGAFGELGEDLVDAILGEAGRFASEEVAPLGDAGDRRGARLVGGTVETPEGWRDLY
HNWIAGGWNGLTAPEAYGGQNLPHMLHVAAMEMWNSGSMAFALAPTLTMGAIEALEKHGTEVLKSVFLPKMVSGEWMGTM
NLTEPHAGSDLGVLKTRAERCDDGTYRIFGQKIFITWGEHDFTDNIVHLVLARLPDAPPGTKGISLFLVPKFLVNGDGSL
GARNDLFCHSLEHKLGIHGSPTCTMIYGDGRFGAEKGAVGYLVGEENRGLACMFTMMNNARLAVGMQGVAIAEAATQKAI
AYAKERRQGRAPGWSGEGMSPIIEHPDVARMLLTMKALTQGSRAIAYACAHAVDMAHFAEGEEARHWQERSSLLTPIAKS
FATDAGVDVASLGVQVHGGMGFIEETGAARYLRDARIAPIYEGTNGIQAIDLVTRKLPLSDGAHVRGFIAELREVTAAVA
ASNRKGFGETAARLDAAIADLEGATAWLLSAIRDGKLAEALAGATAYQRLFGLVLTAIYLAKGGLAEAGDGKQEQRIALC
RFAAENLVSETSALEDRVTNGAESLAAARSILD

Sequences:

>Translated_593_residues
MYKAPVDEIAFTLKHVAGLAEAIDRGAFGELGEDLVDAILGEAGRFASEEVAPLGDAGDRRGARLVGGTVETPEGWRDLY
HNWIAGGWNGLTAPEAYGGQNLPHMLHVAAMEMWNSGSMAFALAPTLTMGAIEALEKHGTEVLKSVFLPKMVSGEWMGTM
NLTEPHAGSDLGVLKTRAERCDDGTYRIFGQKIFITWGEHDFTDNIVHLVLARLPDAPPGTKGISLFLVPKFLVNGDGSL
GARNDLFCHSLEHKLGIHGSPTCTMIYGDGRFGAEKGAVGYLVGEENRGLACMFTMMNNARLAVGMQGVAIAEAATQKAI
AYAKERRQGRAPGWSGEGMSPIIEHPDVARMLLTMKALTQGSRAIAYACAHAVDMAHFAEGEEARHWQERSSLLTPIAKS
FATDAGVDVASLGVQVHGGMGFIEETGAARYLRDARIAPIYEGTNGIQAIDLVTRKLPLSDGAHVRGFIAELREVTAAVA
ASNRKGFGETAARLDAAIADLEGATAWLLSAIRDGKLAEALAGATAYQRLFGLVLTAIYLAKGGLAEAGDGKQEQRIALC
RFAAENLVSETSALEDRVTNGAESLAAARSILD
>Mature_593_residues
MYKAPVDEIAFTLKHVAGLAEAIDRGAFGELGEDLVDAILGEAGRFASEEVAPLGDAGDRRGARLVGGTVETPEGWRDLY
HNWIAGGWNGLTAPEAYGGQNLPHMLHVAAMEMWNSGSMAFALAPTLTMGAIEALEKHGTEVLKSVFLPKMVSGEWMGTM
NLTEPHAGSDLGVLKTRAERCDDGTYRIFGQKIFITWGEHDFTDNIVHLVLARLPDAPPGTKGISLFLVPKFLVNGDGSL
GARNDLFCHSLEHKLGIHGSPTCTMIYGDGRFGAEKGAVGYLVGEENRGLACMFTMMNNARLAVGMQGVAIAEAATQKAI
AYAKERRQGRAPGWSGEGMSPIIEHPDVARMLLTMKALTQGSRAIAYACAHAVDMAHFAEGEEARHWQERSSLLTPIAKS
FATDAGVDVASLGVQVHGGMGFIEETGAARYLRDARIAPIYEGTNGIQAIDLVTRKLPLSDGAHVRGFIAELREVTAAVA
ASNRKGFGETAARLDAAIADLEGATAWLLSAIRDGKLAEALAGATAYQRLFGLVLTAIYLAKGGLAEAGDGKQEQRIALC
RFAAENLVSETSALEDRVTNGAESLAAARSILD

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=409, Percent_Identity=27.1393643031785, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=28.2967032967033, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4501857, Length=345, Percent_Identity=28.1159420289855, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=25.7907542579075, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=27.8688524590164, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI21361497, Length=440, Percent_Identity=26.1363636363636, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI76496475, Length=369, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=369, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557231, Length=320, Percent_Identity=28.4375, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=25.2688172043011, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI187960098, Length=320, Percent_Identity=28.4375, Blast_Score=87, Evalue=6e-17,
Organism=Escherichia coli, GI87082384, Length=340, Percent_Identity=27.9411764705882, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=438, Percent_Identity=28.0821917808219, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=419, Percent_Identity=28.4009546539379, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=307, Percent_Identity=28.3387622149837, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563381, Length=307, Percent_Identity=28.3387622149837, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=390, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=367, Percent_Identity=29.9727520435967, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=427, Percent_Identity=26.2295081967213, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=413, Percent_Identity=27.6029055690073, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=29.8630136986301, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=406, Percent_Identity=26.1083743842365, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=366, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=241, Percent_Identity=28.6307053941909, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=243, Percent_Identity=28.8065843621399, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355753, Length=419, Percent_Identity=27.4463007159904, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI21356377, Length=360, Percent_Identity=28.0555555555556, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=26.4705882352941, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24660351, Length=425, Percent_Identity=28, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363737, Length=370, Percent_Identity=25.6756756756757, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24666513, Length=411, Percent_Identity=24.8175182481752, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 63028; Mature: 63028

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKAPVDEIAFTLKHVAGLAEAIDRGAFGELGEDLVDAILGEAGRFASEEVAPLGDAGDR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGARLVGGTVETPEGWRDLYHNWIAGGWNGLTAPEAYGGQNLPHMLHVAAMEMWNSGSMA
CCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
FALAPTLTMGAIEALEKHGTEVLKSVFLPKMVSGEWMGTMNLTEPHAGSDLGVLKTRAER
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
CDDGTYRIFGQKIFITWGEHDFTDNIVHLVLARLPDAPPGTKGISLFLVPKFLVNGDGSL
CCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCCCCCC
GARNDLFCHSLEHKLGIHGSPTCTMIYGDGRFGAEKGAVGYLVGEENRGLACMFTMMNNA
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCC
RLAVGMQGVAIAEAATQKAIAYAKERRQGRAPGWSGEGMSPIIEHPDVARMLLTMKALTQ
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GSRAIAYACAHAVDMAHFAEGEEARHWQERSSLLTPIAKSFATDAGVDVASLGVQVHGGM
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCC
GFIEETGAARYLRDARIAPIYEGTNGIQAIDLVTRKLPLSDGAHVRGFIAELREVTAAVA
CCHHHCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ASNRKGFGETAARLDAAIADLEGATAWLLSAIRDGKLAEALAGATAYQRLFGLVLTAIYL
HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKGGLAEAGDGKQEQRIALCRFAAENLVSETSALEDRVTNGAESLAAARSILD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MYKAPVDEIAFTLKHVAGLAEAIDRGAFGELGEDLVDAILGEAGRFASEEVAPLGDAGDR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGARLVGGTVETPEGWRDLYHNWIAGGWNGLTAPEAYGGQNLPHMLHVAAMEMWNSGSMA
CCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
FALAPTLTMGAIEALEKHGTEVLKSVFLPKMVSGEWMGTMNLTEPHAGSDLGVLKTRAER
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
CDDGTYRIFGQKIFITWGEHDFTDNIVHLVLARLPDAPPGTKGISLFLVPKFLVNGDGSL
CCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCCCCCC
GARNDLFCHSLEHKLGIHGSPTCTMIYGDGRFGAEKGAVGYLVGEENRGLACMFTMMNNA
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCC
RLAVGMQGVAIAEAATQKAIAYAKERRQGRAPGWSGEGMSPIIEHPDVARMLLTMKALTQ
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GSRAIAYACAHAVDMAHFAEGEEARHWQERSSLLTPIAKSFATDAGVDVASLGVQVHGGM
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCC
GFIEETGAARYLRDARIAPIYEGTNGIQAIDLVTRKLPLSDGAHVRGFIAELREVTAAVA
CCHHHCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ASNRKGFGETAARLDAAIADLEGATAWLLSAIRDGKLAEALAGATAYQRLFGLVLTAIYL
HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKGGLAEAGDGKQEQRIALCRFAAENLVSETSALEDRVTNGAESLAAARSILD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]