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The map label for this gene is ubiA [H]

Identifier: 150395702

GI number: 150395702

Start: 515828

End: 516793

Strand: Direct

Name: ubiA [H]

Synonym: Smed_0477

Alternate gene names: 150395702

Gene position: 515828-516793 (Clockwise)

Preceding gene: 150395701

Following gene: 150395704

Centisome position: 13.64

GC content: 62.01

Gene sequence:

>966_bases
GTGGCTATGAACAGCTCTTCCATCGATTCCGGCCGCGTCCACGATGCGCCGTCCAACAATTGGGTCTACCGGGTCTTGCC
GCGAGCGCTATGGCCCTATGCGCAGCTCGCCCGCTGGGACCGTCCGATCGGCTGGCAATTGTTGATGTGGCCATGCCTCT
GGTCCGCCGCGATGGCAGCCGGAGCGGCCGCATCGCTCGGCAGCTTCTCGGCCGGGCGTTTCCTCTTCCATATCTTTCTC
TTCATCGTCGGGGCGATCGCCATGCGTGGCGCCGGCTGCACCTACAACGACATCGTCGATCACGATATCGACATGGAAGT
CGCTCGTACACGCTCGCGCCCGCTACCTTCCGGTCGCGTAACGCGCTTCCAGGCGAAGGCATTCATGTTGCTGCAGTCGG
TTGTGGGTCTTGCCGTCCTGCTACAGTTCAACGGGTTCACGATTTTTCTCGGCGTGCTGTCGCTCGCGTTGGTGGCGATC
TATCCGTTCGCCAAGCGCTTTACGGATTGGCCGCAATTCTTCCTCGGCCTCGCCTTCTCCTGGGGCGCGATCATGGGCTG
GGCGGCGGAATTCGGCAGCCTGTCCTTCGCGCCGGTCATGCTCTACGCGGCGGCCATCACCTGGACGATCGGCTATGACA
CGATCTATGCCTATCAGGACAGGGAGGACGACGAACTGATCGGCGTTCGCTCGACAGCCCGCCGCTTCGGCGACAATCCG
CGGCCGTGGCTGATCGGGCTCTATGGGATCGCCGTTCTCCTGATGCTTTTCGCGTTCCTCGCGGCCGGCGCCGGCTTCTT
CGCCTATCTAGGGCTTGTGGTGGCGGCGGTGATGCTCGCCTATCAGATACTGGTGTTGAACATCCACGATCCGCTGCAAT
GCCTCGCGCTGTTCAAGTTCAACGGCGTCGTCGGCCTCATCATCTTTGCCGGACTGGTGCTCTCGCTTCTCGTTCGCCTG
ATATGA

Upstream 100 bases:

>100_bases
CGACCTACCGCTTCGATTTTACGCTACCCTGACTGGTGCCTGAAGGATCGGACGGGATTGAAACGGGGCGCTTGACCGGC
CGTGTTTGCAGGGCCAAACA

Downstream 100 bases:

>100_bases
AAAATCCTCCGGAATCCGGAGGATTGTCGGTAGAGCCAAATCGATACGAAATCCCAGCGGAAACGCCGGTTTTATGCCCA
ACTCGATTCGGTCGCCACCT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAMNSSSIDSGRVHDAPSNNWVYRVLPRALWPYAQLARWDRPIGWQLLMWPCLWSAAMAAGAAASLGSFSAGRFLFHIFL
FIVGAIAMRGAGCTYNDIVDHDIDMEVARTRSRPLPSGRVTRFQAKAFMLLQSVVGLAVLLQFNGFTIFLGVLSLALVAI
YPFAKRFTDWPQFFLGLAFSWGAIMGWAAEFGSLSFAPVMLYAAAITWTIGYDTIYAYQDREDDELIGVRSTARRFGDNP
RPWLIGLYGIAVLLMLFAFLAAGAGFFAYLGLVVAAVMLAYQILVLNIHDPLQCLALFKFNGVVGLIIFAGLVLSLLVRL
I

Sequences:

>Translated_321_residues
MAMNSSSIDSGRVHDAPSNNWVYRVLPRALWPYAQLARWDRPIGWQLLMWPCLWSAAMAAGAAASLGSFSAGRFLFHIFL
FIVGAIAMRGAGCTYNDIVDHDIDMEVARTRSRPLPSGRVTRFQAKAFMLLQSVVGLAVLLQFNGFTIFLGVLSLALVAI
YPFAKRFTDWPQFFLGLAFSWGAIMGWAAEFGSLSFAPVMLYAAAITWTIGYDTIYAYQDREDDELIGVRSTARRFGDNP
RPWLIGLYGIAVLLMLFAFLAAGAGFFAYLGLVVAAVMLAYQILVLNIHDPLQCLALFKFNGVVGLIIFAGLVLSLLVRL
I
>Mature_320_residues
AMNSSSIDSGRVHDAPSNNWVYRVLPRALWPYAQLARWDRPIGWQLLMWPCLWSAAMAAGAAASLGSFSAGRFLFHIFLF
IVGAIAMRGAGCTYNDIVDHDIDMEVARTRSRPLPSGRVTRFQAKAFMLLQSVVGLAVLLQFNGFTIFLGVLSLALVAIY
PFAKRFTDWPQFFLGLAFSWGAIMGWAAEFGSLSFAPVMLYAAAITWTIGYDTIYAYQDREDDELIGVRSTARRFGDNPR
PWLIGLYGIAVLLMLFAFLAAGAGFFAYLGLVVAAVMLAYQILVLNIHDPLQCLALFKFNGVVGLIIFAGLVLSLLVRLI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=296, Percent_Identity=45.6081081081081, Blast_Score=224, Evalue=6e-59,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=37.3239436619718, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17553718, Length=297, Percent_Identity=44.1077441077441, Blast_Score=220, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI32565247, Length=298, Percent_Identity=41.2751677852349, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17553720, Length=352, Percent_Identity=33.5227272727273, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI32565245, Length=150, Percent_Identity=47.3333333333333, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=149, Percent_Identity=46.9798657718121, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324370, Length=301, Percent_Identity=37.2093023255814, Blast_Score=165, Evalue=7e-42,
Organism=Drosophila melanogaster, GI21355567, Length=332, Percent_Identity=45.1807228915663, Blast_Score=244, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35431; Mature: 35300

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMNSSSIDSGRVHDAPSNNWVYRVLPRALWPYAQLARWDRPIGWQLLMWPCLWSAAMAA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GAAASLGSFSAGRFLFHIFLFIVGAIAMRGAGCTYNDIVDHDIDMEVARTRSRPLPSGRV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCC
TRFQAKAFMLLQSVVGLAVLLQFNGFTIFLGVLSLALVAIYPFAKRFTDWPQFFLGLAFS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
WGAIMGWAAEFGSLSFAPVMLYAAAITWTIGYDTIYAYQDREDDELIGVRSTARRFGDNP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCHHEHHHHHHHHCCCCC
RPWLIGLYGIAVLLMLFAFLAAGAGFFAYLGLVVAAVMLAYQILVLNIHDPLQCLALFKF
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NGVVGLIIFAGLVLSLLVRLI
CCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AMNSSSIDSGRVHDAPSNNWVYRVLPRALWPYAQLARWDRPIGWQLLMWPCLWSAAMAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GAAASLGSFSAGRFLFHIFLFIVGAIAMRGAGCTYNDIVDHDIDMEVARTRSRPLPSGRV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCC
TRFQAKAFMLLQSVVGLAVLLQFNGFTIFLGVLSLALVAIYPFAKRFTDWPQFFLGLAFS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
WGAIMGWAAEFGSLSFAPVMLYAAAITWTIGYDTIYAYQDREDDELIGVRSTARRFGDNP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCHHEHHHHHHHHCCCCC
RPWLIGLYGIAVLLMLFAFLAAGAGFFAYLGLVVAAVMLAYQILVLNIHDPLQCLALFKF
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NGVVGLIIFAGLVLSLLVRLI
CCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA