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The map label for this gene is cysQ [H]

Identifier: 150395647

GI number: 150395647

Start: 456479

End: 457297

Strand: Direct

Name: cysQ [H]

Synonym: Smed_0422

Alternate gene names: 150395647

Gene position: 456479-457297 (Clockwise)

Preceding gene: 150395646

Following gene: 150395648

Centisome position: 12.07

GC content: 64.22

Gene sequence:

>819_bases
ATGTCAGAAACAGCCCATTCGATCGTGCCCGCCTGGGGCCAGGATCTCGAGCTCATTCTTGCGGCAGCAGTCGCGGCGGG
TGACACGGCGCTCGGCTATTTTCGCAAGACGCTGGACGTTCGCTGGAAAAATGAAGGACGCTCTCCCGTCAGCGAGGCCG
ACCTTGCCGCCAACGACATCCTCAAGAGTCGGCTGCTCTCTGCCCGGCCGGACTATGGCTGGCTTTCGGAGGAGACCGAC
GACGATGAAAGCCGTCTCCTTCGCGAGACTGTCTTCGTTGTCGATCCGATCGACGGGACCCGGGCCTTCATCGCGGGGAA
GGACCTCTGGTGCGTCAGCGTCGCCGTCGTTCATCGCGGACTTCCCGTGGCTGGCGTGCTCTATGCACCGTCCCTCGGCG
AGATATTCCAGGCGACCCGCGACGGCGAAGTGCGGAAGAACGGCAAACCGATCGCGGTGCGGGAGACGGCCTCGGGCGCG
GTGCTGAAGGTGGCAGCGGCCGAGGATATCATGGGCAAGCTGGCTCTGCCCTATCGCAAGACGATGATGCGCGTATCACA
TGTACCGTCGCTCGCCTATCGGCTTGCGATGATCGCGGACGGCCGTATCGACGGAACGATCGTCAAGCGGAACTCGCATG
ATTGGGATCTCGCGGCCGCCGACCTCATTCTTTCGCGCGCCGGCGGCGCGCTTTGCGGTCTCGACAACGAGCCCTTGTTC
TACAATCGCCCGACCGTCACCCACGGCGTTCTTGCCGCGGCATCGGGGGCGGCGCTACCGGCCTTGCTGGCCGCTTCCAG
GCCTCTTGAGCCCCATTGA

Upstream 100 bases:

>100_bases
CGTGCCCCGCGTCTAAACTCTTTGGAATCGATCGCGCTCATTTTTTGGGTCGATCCGACCTAAACATCGTGATCTAAAGG
CGCCGCTCGTAAGGAGTTGC

Downstream 100 bases:

>100_bases
CCTTTAGGGGCGAATGCCGCAAACCACCCCCATACCAGTAAGAACACAGATGGAAATTCCATGGCTCACGACTCCGAGAA
AAAACAACGGCTGCACCTCG

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSETAHSIVPAWGQDLELILAAAVAAGDTALGYFRKTLDVRWKNEGRSPVSEADLAANDILKSRLLSARPDYGWLSEETD
DDESRLLRETVFVVDPIDGTRAFIAGKDLWCVSVAVVHRGLPVAGVLYAPSLGEIFQATRDGEVRKNGKPIAVRETASGA
VLKVAAAEDIMGKLALPYRKTMMRVSHVPSLAYRLAMIADGRIDGTIVKRNSHDWDLAAADLILSRAGGALCGLDNEPLF
YNRPTVTHGVLAAASGAALPALLAASRPLEPH

Sequences:

>Translated_272_residues
MSETAHSIVPAWGQDLELILAAAVAAGDTALGYFRKTLDVRWKNEGRSPVSEADLAANDILKSRLLSARPDYGWLSEETD
DDESRLLRETVFVVDPIDGTRAFIAGKDLWCVSVAVVHRGLPVAGVLYAPSLGEIFQATRDGEVRKNGKPIAVRETASGA
VLKVAAAEDIMGKLALPYRKTMMRVSHVPSLAYRLAMIADGRIDGTIVKRNSHDWDLAAADLILSRAGGALCGLDNEPLF
YNRPTVTHGVLAAASGAALPALLAASRPLEPH
>Mature_271_residues
SETAHSIVPAWGQDLELILAAAVAAGDTALGYFRKTLDVRWKNEGRSPVSEADLAANDILKSRLLSARPDYGWLSEETDD
DESRLLRETVFVVDPIDGTRAFIAGKDLWCVSVAVVHRGLPVAGVLYAPSLGEIFQATRDGEVRKNGKPIAVRETASGAV
LKVAAAEDIMGKLALPYRKTMMRVSHVPSLAYRLAMIADGRIDGTIVKRNSHDWDLAAADLILSRAGGALCGLDNEPLFY
NRPTVTHGVLAAASGAALPALLAASRPLEPH

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788882, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790659, Length=126, Percent_Identity=34.1269841269841, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320493, Length=219, Percent_Identity=26.027397260274, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357957, Length=229, Percent_Identity=27.0742358078603, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664922, Length=213, Percent_Identity=26.2910798122066, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29131; Mature: 28999

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETAHSIVPAWGQDLELILAAAVAAGDTALGYFRKTLDVRWKNEGRSPVSEADLAANDI
CCCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
LKSRLLSARPDYGWLSEETDDDESRLLRETVFVVDPIDGTRAFIAGKDLWCVSVAVVHRG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHCC
LPVAGVLYAPSLGEIFQATRDGEVRKNGKPIAVRETASGAVLKVAAAEDIMGKLALPYRK
CCEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHCCHHHH
TMMRVSHVPSLAYRLAMIADGRIDGTIVKRNSHDWDLAAADLILSRAGGALCGLDNEPLF
HHHHHHHCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCEE
YNRPTVTHGVLAAASGAALPALLAASRPLEPH
ECCCCHHHHHHHHCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SETAHSIVPAWGQDLELILAAAVAAGDTALGYFRKTLDVRWKNEGRSPVSEADLAANDI
CCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
LKSRLLSARPDYGWLSEETDDDESRLLRETVFVVDPIDGTRAFIAGKDLWCVSVAVVHRG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHCC
LPVAGVLYAPSLGEIFQATRDGEVRKNGKPIAVRETASGAVLKVAAAEDIMGKLALPYRK
CCEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHCCHHHH
TMMRVSHVPSLAYRLAMIADGRIDGTIVKRNSHDWDLAAADLILSRAGGALCGLDNEPLF
HHHHHHHCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCEE
YNRPTVTHGVLAAASGAALPALLAASRPLEPH
ECCCCHHHHHHHHCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]