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The map label for this gene is lsrC [H]

Identifier: 150395454

GI number: 150395454

Start: 251880

End: 252860

Strand: Direct

Name: lsrC [H]

Synonym: Smed_0227

Alternate gene names: 150395454

Gene position: 251880-252860 (Clockwise)

Preceding gene: 150395453

Following gene: 150395455

Centisome position: 6.66

GC content: 61.57

Gene sequence:

>981_bases
ATGATGGCCAAGCTCCTCAAGAACCGTGAAATCCTGCTCGTCGTTGCGATTGCGGTGCTGCTCGCTATCATCGCCTTGCG
CTTCCCGGCTTTCGTGGCGCCGTCCAATCTCGCGCGCGTCTATAACGACACCTCGATCCTCGTCATCCTGGCGCTTGGAC
AGATGGCGGTTATTCTTACCCGCTGCATCGACCTGTCGATGGCGGCCAACCTCGCGCTCTGCGGCATGGTGGCAGCCATG
CTGAACAATTTCTTCCCCGGCCTGCCGATCCCACTCATCATTTTTGCCGCCATGGCGCTGGGCGGGTTCCTCGGCGCGAT
CAACGGTACGCTGGTCTGGAAGCTCAACATTCCGCCGATCGTCGTGACCCTAGGGACTTTGACGATCTACCGCGGTCTCA
TCTTCGTTTTGACGAACGGCAAATGGATCAATGCGCATGAGATGAGCGACCCCTTCAAGGCGCTGCCGCGGCTGGTCGTC
GCCGGCATGCCGGTGCTTTCCTGGCTCTCCTTCCTCATGATAGCGCTGATGTTCCTGGTCATCGGACGTACGCCGCTCGG
CCGCGCCTTCTATGCCGTCGGGGGCAATCCGCATGCGGCCGTCTACACCGGCATCGATGTCGGCCGGACGCGCTTCTTCG
CCTATTGTCTCTCGGGTACGCTTGCGGGCCTGTCAGGTTATCTCTGGGTATCGCGTTATGCCGTCGCCTATGTGGACATC
GCCGCCGGATTCGAGCTCGACATCATCGCGGCCTGCGTCATCGGCGGCATTTCGATTGCCGGCGGCATCGGCTCCGTGGC
TGGTGCGGTGCTCGGAGCACTCTTCCTCGGCGTGATCAAGAACGCGCTGCCGGTCATCGATATCTCGCCCTTCGCGCAGT
TGGCGATATCCGGAACGGTCATCATCATCGCGGTTGCCGTCAATGCCCGCGCCGAGCGGCGCAAGGGCAGGGTCATTCTC
AAGAAAGCGGAGGCGGTCTGA

Upstream 100 bases:

>100_bases
AGGGCCGCGTCGCCGGAAGGTTCGAACGATCGGAACTGACTGCCGAGAAGCTGGTGCGGGCTGCCGCGGGCATCGAAACG
CAAGCCGGCGGGGGAGCAGC

Downstream 100 bases:

>100_bases
TGGCTGACGCGCAAATCTCTCCCCGCAACATTCCCGACCGACTGGAGGGGCGCGGCGCTCGCCTCCTGAAGAGCTGGGAA
GCGCTGCTCGTGGTGGTCGC

Product: monosaccharide-transporting ATPase

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MMAKLLKNREILLVVAIAVLLAIIALRFPAFVAPSNLARVYNDTSILVILALGQMAVILTRCIDLSMAANLALCGMVAAM
LNNFFPGLPIPLIIFAAMALGGFLGAINGTLVWKLNIPPIVVTLGTLTIYRGLIFVLTNGKWINAHEMSDPFKALPRLVV
AGMPVLSWLSFLMIALMFLVIGRTPLGRAFYAVGGNPHAAVYTGIDVGRTRFFAYCLSGTLAGLSGYLWVSRYAVAYVDI
AAGFELDIIAACVIGGISIAGGIGSVAGAVLGALFLGVIKNALPVIDISPFAQLAISGTVIIIAVAVNARAERRKGRVIL
KKAEAV

Sequences:

>Translated_326_residues
MMAKLLKNREILLVVAIAVLLAIIALRFPAFVAPSNLARVYNDTSILVILALGQMAVILTRCIDLSMAANLALCGMVAAM
LNNFFPGLPIPLIIFAAMALGGFLGAINGTLVWKLNIPPIVVTLGTLTIYRGLIFVLTNGKWINAHEMSDPFKALPRLVV
AGMPVLSWLSFLMIALMFLVIGRTPLGRAFYAVGGNPHAAVYTGIDVGRTRFFAYCLSGTLAGLSGYLWVSRYAVAYVDI
AAGFELDIIAACVIGGISIAGGIGSVAGAVLGALFLGVIKNALPVIDISPFAQLAISGTVIIIAVAVNARAERRKGRVIL
KKAEAV
>Mature_326_residues
MMAKLLKNREILLVVAIAVLLAIIALRFPAFVAPSNLARVYNDTSILVILALGQMAVILTRCIDLSMAANLALCGMVAAM
LNNFFPGLPIPLIIFAAMALGGFLGAINGTLVWKLNIPPIVVTLGTLTIYRGLIFVLTNGKWINAHEMSDPFKALPRLVV
AGMPVLSWLSFLMIALMFLVIGRTPLGRAFYAVGGNPHAAVYTGIDVGRTRFFAYCLSGTLAGLSGYLWVSRYAVAYVDI
AAGFELDIIAACVIGGISIAGGIGSVAGAVLGALFLGVIKNALPVIDISPFAQLAISGTVIIIAVAVNARAERRKGRVIL
KKAEAV

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=303, Percent_Identity=34.3234323432343, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787793, Length=310, Percent_Identity=34.8387096774194, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI145693152, Length=306, Percent_Identity=32.0261437908497, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790524, Length=294, Percent_Identity=34.6938775510204, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788896, Length=311, Percent_Identity=32.1543408360129, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788471, Length=324, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082395, Length=284, Percent_Identity=31.3380281690141, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1789992, Length=139, Percent_Identity=39.568345323741, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1787794, Length=272, Percent_Identity=30.8823529411765, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693214, Length=238, Percent_Identity=31.0924369747899, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34351; Mature: 34351

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAKLLKNREILLVVAIAVLLAIIALRFPAFVAPSNLARVYNDTSILVILALGQMAVILT
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
RCIDLSMAANLALCGMVAAMLNNFFPGLPIPLIIFAAMALGGFLGAINGTLVWKLNIPPI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
VVTLGTLTIYRGLIFVLTNGKWINAHEMSDPFKALPRLVVAGMPVLSWLSFLMIALMFLV
HHHHHHHHHHHCEEEEEECCEEEEHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IGRTPLGRAFYAVGGNPHAAVYTGIDVGRTRFFAYCLSGTLAGLSGYLWVSRYAVAYVDI
HCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEH
AAGFELDIIAACVIGGISIAGGIGSVAGAVLGALFLGVIKNALPVIDISPFAQLAISGTV
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCEE
IIIAVAVNARAERRKGRVILKKAEAV
EEEEEEECCHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MMAKLLKNREILLVVAIAVLLAIIALRFPAFVAPSNLARVYNDTSILVILALGQMAVILT
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
RCIDLSMAANLALCGMVAAMLNNFFPGLPIPLIIFAAMALGGFLGAINGTLVWKLNIPPI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
VVTLGTLTIYRGLIFVLTNGKWINAHEMSDPFKALPRLVVAGMPVLSWLSFLMIALMFLV
HHHHHHHHHHHCEEEEEECCEEEEHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IGRTPLGRAFYAVGGNPHAAVYTGIDVGRTRFFAYCLSGTLAGLSGYLWVSRYAVAYVDI
HCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEH
AAGFELDIIAACVIGGISIAGGIGSVAGAVLGALFLGVIKNALPVIDISPFAQLAISGTV
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCEE
IIIAVAVNARAERRKGRVILKKAEAV
EEEEEEECCHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]