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The map label for this gene is murA [H]

Identifier: 150395433

GI number: 150395433

Start: 233241

End: 234533

Strand: Direct

Name: murA [H]

Synonym: Smed_0206

Alternate gene names: 150395433

Gene position: 233241-234533 (Clockwise)

Preceding gene: 150395432

Following gene: 150395434

Centisome position: 6.17

GC content: 65.2

Gene sequence:

>1293_bases
ATGGATCGCATCAGGATTGTAGGCGGAAATGAACTCCACGGGGTGATCCCCATCTCCGGCGCGAAGAACGCCGCCTTGCC
GCTGATGATCGCGTCGCTCCTGACCGATGACACGCTGACGCTCGAAAATGTGCCGCATCTCGCCGATGTCGAGCAATTGA
TCCGCATCCTCGGCAATCATGGTGCCGACATTTCCGTCAATGGCCGGCGCGAGCGTCAGGGCGAGAGCTACGCCCGCACG
GTCCATTTCACCAGCCGCAACATCGTTTCGACGACTGCACCCTATGAGCTCGTCTCGAAGATGCGCGCGAGCTTCTGGGT
CATCGGGCCGCTGCTCGCGCGTGAGGGCAGGGCGCGCGTGTCGCTGCCCGGCGGTTGCGCCATCGGAACGCGCCCGGTTG
ATCTCTTCATCGAGGGGCTGACCGCGCTTGGCGCCAGCATTGAGATCGACGGCGGCTACGTCAATGCAACGGCACCGGCG
GGCGGGCTCATCGGCGGGCGTTACACCTTCCCGAAAGTTTCCGTCGGCGCGACCCATGTGCTGATGATGGCGGCAACGCT
TGCCAATGGCACGACGGTGCTCGGCAACGCCGCGCGTGAGCCCGAAGTGGTGGACCTTGCCAAATGCCTGAACGCCATGG
GCGCGAAGATCAGCGGCCAGGGGACGAGCACGATCACCATCGAGGGCGTGCGCTCGCTCTCGGGCGCCCGCCACCGGGTG
CTGCCCGATCGCATCGAGACAGGGACCTATGCGATGGCCGTCGCCATGGCGGGCGGCGACGTCATTCTCGAAGACACCGA
GGCGAGCCTCCTCGATACAGCGCTTGAAGCGATCCGCCGCGCCGGCGCCGAGATCAGCGACACGAACAACGGCATCCGGA
TCGTCCGCAACGGCGCCGGCATCAGGCCGGTCGACATCGTCACCGATCCCTTCCCCGGCTTCCCGACCGACCTTCAGGCG
CAGTTCATGGGGTTGATGACCCGGTCAAGCGGCGTTTCCCACATCACCGAGACGATCTTTGAAAACCGCTTCATGCATGT
TCAGGAGCTGGCGCGGCTCGGCGCCAAGATATCGCTCTCCGGCCAGACGGCGAAGGTCGAGGGTGTATCGCGGCTGAAGG
GCGCACCGGTCATGGCAACGGACCTCAGGGCTTCCGTCTCGCTCGTCATTGCGGGCCTCGCGGCCGAGGGCGAAACCATG
GTTTCGCGGGTTTACCACCTCGACCGCGGCTTCGAGCGCCTGGAAGAGAAGCTCACGCGTTGCGGCGCCCATGTCGAGCG
CGTCAGCGACTGA

Upstream 100 bases:

>100_bases
ACTTCTAATTTCACCGCATCTCCACTAAGAGACGCCCTTCAACAATGCCGGTCGGCATCGATTTTCCAGAAAGGCGGGCA
GCGCCCGTGCGAGAGGTCTC

Downstream 100 bases:

>100_bases
TTGTTCAGCTCAGCGCCGGGAGCCGTTGCGGTTTCCGGCGCAACGTCCTATGTCCTACAGCTGTAGCATGACAAGGACGG
GGTGGATCGCATGGATGCTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGADISVNGRRERQGESYART
VHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLTALGASIEIDGGYVNATAPA
GGLIGGRYTFPKVSVGATHVLMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTITIEGVRSLSGARHRV
LPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAEISDTNNGIRIVRNGAGIRPVDIVTDPFPGFPTDLQA
QFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLSGQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETM
VSRVYHLDRGFERLEEKLTRCGAHVERVSD

Sequences:

>Translated_430_residues
MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGADISVNGRRERQGESYART
VHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLTALGASIEIDGGYVNATAPA
GGLIGGRYTFPKVSVGATHVLMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTITIEGVRSLSGARHRV
LPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAEISDTNNGIRIVRNGAGIRPVDIVTDPFPGFPTDLQA
QFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLSGQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETM
VSRVYHLDRGFERLEEKLTRCGAHVERVSD
>Mature_430_residues
MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGADISVNGRRERQGESYART
VHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLTALGASIEIDGGYVNATAPA
GGLIGGRYTFPKVSVGATHVLMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTITIEGVRSLSGARHRV
LPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAEISDTNNGIRIVRNGAGIRPVDIVTDPFPGFPTDLQA
QFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLSGQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETM
VSRVYHLDRGFERLEEKLTRCGAHVERVSD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=50.5827505827506, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45510; Mature: 45510

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GADISVNGRRERQGESYARTVHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGRARV
CCEEEECCCHHHCCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHEEHHHHHHCCCCCEE
SLPGGCAIGTRPVDLFIEGLTALGASIEIDGGYVNATAPAGGLIGGRYTFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCEECCCCCCCHHHH
LMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTITIEGVRSLSGARHRV
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCEECCCCCEEEEEEEHHHCCCCCCCC
LPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAEISDTNNGIRIVRNGAG
CCCHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
IRPVDIVTDPFPGFPTDLQAQFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLS
CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETMVSRVYHLDRGFERLEEKLTR
CCCEEECHHHHHCCCCEEEHHHHHHEEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
CGAHVERVSD
HHHHHHHCCC
>Mature Secondary Structure
MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GADISVNGRRERQGESYARTVHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGRARV
CCEEEECCCHHHCCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHEEHHHHHHCCCCCEE
SLPGGCAIGTRPVDLFIEGLTALGASIEIDGGYVNATAPAGGLIGGRYTFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCEECCCCCCCHHHH
LMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTITIEGVRSLSGARHRV
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCEECCCCCEEEEEEEHHHCCCCCCCC
LPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAEISDTNNGIRIVRNGAG
CCCHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
IRPVDIVTDPFPGFPTDLQAQFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLS
CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETMVSRVYHLDRGFERLEEKLTR
CCCEEECHHHHHCCCCEEEHHHHHHEEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
CGAHVERVSD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]