Click here to switch to the map view.

The map label for this gene is tktB [C]

Identifier: 150401925

GI number: 150401925

Start: 1564785

End: 1565603

Strand: Direct

Name: tktB [C]

Synonym: Maeo_1503

Alternate gene names: 150401925

Gene position: 1564785-1565603 (Clockwise)

Preceding gene: 150401924

Following gene: 150401926

Centisome position: 99.7

GC content: 33.94

Gene sequence:

>819_bases
ATGGATAATATATCAATTGATGAATTAAAAACCATTTCTAAAAAAATAAGATATAATATCGTAAAAATGATAGGTTTGGC
AAATTCTGGACACCCTGGTGGTTCATTGTCGGCCACAGATATTGTAGTTTCTTTATATTATGGTATTATGAATATTGACC
CAAAAAATCCAAATAAAAAAGATAGGGATAGATTTGTATTGAGTAAAGGGCATGCTTCTCCTGTCATATATTCGGTTCTT
GCAGAATTAGGATTTTTTGATAAAGAAGAATTATGGAGATTTAGACAAACTGGAGGATTATTACAAGGACATCCAAATAT
AAAAATTCCTGGAATTGAGGCAAACACTGGTTCATTAGGTCATGGGATATCTGTTGCAGTGGGAATGGCATTGGGTTGTA
AATTAGATAAGTTAGATAATATGGTTTATACTCTTTTAGGAGATGGAGAATGTCAAGAAGGTCAAGTGTGGGAAGCTGCA
ATGGCTGCAAGTCATTATAAATTAGATAATTTGATAGGTTTTGTAGATAGAAACAGACTTCAAATTGATGGGTCTACAAA
AGATGTAATGTGCTTAGGGGACATTTCTGAAAAATTCAAAGCATTTGGCTGGGATGTTTATGAAATTGACGGGCATGATT
ACAATCAAATAATAAATACAATCAACACTGCAAAATCCCAAAAAAACGGAGCTCCCAAAATGATAATAGCTAACACTATT
AAAGGTAAAGGCGTTTCATTCATGGAAGATAATGTGGCATTCCACGGAAAAGCCCCAAATAAAGAGGAGTTAAAACAGGC
ATTGGAGGAGCTCTCCTAA

Upstream 100 bases:

>100_bases
AAAATATAAATCATATAGTAAATAAAATAGATAAATAAATTAAATAAACTTAAAATTATATTAAATTGATATTAATTAAT
ATGTATATATTGGTGAAAAT

Downstream 100 bases:

>100_bases
TAGTTAATCTTCGGACAATTTCACTAAATCATCTCTATAATTAAGCTAAAATATATATTGAATTACTAAAACCAAAGAAA
CTAGTTTAATATATGGCGCA

Product: transketolase domain-containing protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDNISIDELKTISKKIRYNIVKMIGLANSGHPGGSLSATDIVVSLYYGIMNIDPKNPNKKDRDRFVLSKGHASPVIYSVL
AELGFFDKEELWRFRQTGGLLQGHPNIKIPGIEANTGSLGHGISVAVGMALGCKLDKLDNMVYTLLGDGECQEGQVWEAA
MAASHYKLDNLIGFVDRNRLQIDGSTKDVMCLGDISEKFKAFGWDVYEIDGHDYNQIINTINTAKSQKNGAPKMIIANTI
KGKGVSFMEDNVAFHGKAPNKEELKQALEELS

Sequences:

>Translated_272_residues
MDNISIDELKTISKKIRYNIVKMIGLANSGHPGGSLSATDIVVSLYYGIMNIDPKNPNKKDRDRFVLSKGHASPVIYSVL
AELGFFDKEELWRFRQTGGLLQGHPNIKIPGIEANTGSLGHGISVAVGMALGCKLDKLDNMVYTLLGDGECQEGQVWEAA
MAASHYKLDNLIGFVDRNRLQIDGSTKDVMCLGDISEKFKAFGWDVYEIDGHDYNQIINTINTAKSQKNGAPKMIIANTI
KGKGVSFMEDNVAFHGKAPNKEELKQALEELS
>Mature_272_residues
MDNISIDELKTISKKIRYNIVKMIGLANSGHPGGSLSATDIVVSLYYGIMNIDPKNPNKKDRDRFVLSKGHASPVIYSVL
AELGFFDKEELWRFRQTGGLLQGHPNIKIPGIEANTGSLGHGISVAVGMALGCKLDKLDNMVYTLLGDGECQEGQVWEAA
MAASHYKLDNLIGFVDRNRLQIDGSTKDVMCLGDISEKFKAFGWDVYEIDGHDYNQIINTINTAKSQKNGAPKMIIANTI
KGKGVSFMEDNVAFHGKAPNKEELKQALEELS

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=271, Percent_Identity=38.7453874538745, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI4507521, Length=271, Percent_Identity=38.7453874538745, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI133778974, Length=260, Percent_Identity=36.1538461538462, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI225637459, Length=271, Percent_Identity=30.9963099630996, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI225637461, Length=233, Percent_Identity=32.618025751073, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI225637463, Length=228, Percent_Identity=32.8947368421053, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1788808, Length=275, Percent_Identity=36, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI48994911, Length=275, Percent_Identity=35.2727272727273, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786304, Length=275, Percent_Identity=25.4545454545455, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17539652, Length=252, Percent_Identity=40.0793650793651, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6325331, Length=274, Percent_Identity=37.956204379562, Blast_Score=155, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6319593, Length=279, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666278, Length=246, Percent_Identity=39.0243902439024, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI45551847, Length=254, Percent_Identity=37.007874015748, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI45550715, Length=254, Percent_Identity=37.007874015748, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24645119, Length=214, Percent_Identity=39.2523364485981, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29879; Mature: 29879

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNISIDELKTISKKIRYNIVKMIGLANSGHPGGSLSATDIVVSLYYGIMNIDPKNPNKK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCC
DRDRFVLSKGHASPVIYSVLAELGFFDKEELWRFRQTGGLLQGHPNIKIPGIEANTGSLG
CHHHEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCC
HGISVAVGMALGCKLDKLDNMVYTLLGDGECQEGQVWEAAMAASHYKLDNLIGFVDRNRL
CCHHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
QIDGSTKDVMCLGDISEKFKAFGWDVYEIDGHDYNQIINTINTAKSQKNGAPKMIIANTI
EECCCCCCEEEECCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
KGKGVSFMEDNVAFHGKAPNKEELKQALEELS
CCCCCEEEECCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MDNISIDELKTISKKIRYNIVKMIGLANSGHPGGSLSATDIVVSLYYGIMNIDPKNPNKK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCC
DRDRFVLSKGHASPVIYSVLAELGFFDKEELWRFRQTGGLLQGHPNIKIPGIEANTGSLG
CHHHEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCC
HGISVAVGMALGCKLDKLDNMVYTLLGDGECQEGQVWEAAMAASHYKLDNLIGFVDRNRL
CCHHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
QIDGSTKDVMCLGDISEKFKAFGWDVYEIDGHDYNQIINTINTAKSQKNGAPKMIIANTI
EECCCCCCEEEECCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
KGKGVSFMEDNVAFHGKAPNKEELKQALEELS
CCCCCEEEECCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]