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The map label for this gene is apt

Identifier: 150401918

GI number: 150401918

Start: 1558947

End: 1559498

Strand: Direct

Name: apt

Synonym: Maeo_1496

Alternate gene names: 150401918

Gene position: 1558947-1559498 (Clockwise)

Preceding gene: 150401917

Following gene: 150401919

Centisome position: 99.33

GC content: 32.07

Gene sequence:

>552_bases
ATGAAAATATTAGAACGGAGTTTAAAAACCTGCCCAATAGTTCAAAGGGGAGAATATACTTACTTCATACATCCCATATC
AGACGGAGTTCCATTAATAAAACCAGATTTGATAAGGGAAATTACCACAGAAATTATTAAAATAGGGGATTTAAATGTGG
ATAAAATAATCACTGCTGAGGCTATGGGAATACCACTTGCAACAGCAATTTCACTATGTACAGATATCCCATATGCAATT
ATACGAAAAAGAGAGTATAAATTAGATGGGGAAATTGCAGTCCATCAGGAAACAGGATATAGTAAAGGAGAATTATATTT
AAATGGAGTTAATAAAGGAGATAAAGTAATAATTGTAGATGATGTATTATCTACGGGTGGAACGATAATAGCTTTAATTG
AAGCACTACGAAAAGCAGGGGCCGAAATAAAGGACATAATTTGTGTAATTGAAAGAGGAGATGGCAAAAAAATCGTAAAA
GAAAAAACAGGCCATACCGTAAAAACACTTATGAAAATAGATGTAATTGATGGAAAAGTTGTAATTTTATAA

Upstream 100 bases:

>100_bases
ATAGTGTGAAACAGTTCGAAGATTGACTATAATATAAAATTAAATAAAAATAAAATTAGAATATATAAATAAAAATAAAA
AAACACTAAAAAGGGATAAT

Downstream 100 bases:

>100_bases
TAATTTTATTTTTATTTTTTGGGAGCTCCCAAAAATACTACACAAAAACACCACATATATAAAATTGATAATATGATGAG
AATACTTGATTTAGATTTAG

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKILERSLKTCPIVQRGEYTYFIHPISDGVPLIKPDLIREITTEIIKIGDLNVDKIITAEAMGIPLATAISLCTDIPYAI
IRKREYKLDGEIAVHQETGYSKGELYLNGVNKGDKVIIVDDVLSTGGTIIALIEALRKAGAEIKDIICVIERGDGKKIVK
EKTGHTVKTLMKIDVIDGKVVIL

Sequences:

>Translated_183_residues
MKILERSLKTCPIVQRGEYTYFIHPISDGVPLIKPDLIREITTEIIKIGDLNVDKIITAEAMGIPLATAISLCTDIPYAI
IRKREYKLDGEIAVHQETGYSKGELYLNGVNKGDKVIIVDDVLSTGGTIIALIEALRKAGAEIKDIICVIERGDGKKIVK
EKTGHTVKTLMKIDVIDGKVVIL
>Mature_183_residues
MKILERSLKTCPIVQRGEYTYFIHPISDGVPLIKPDLIREITTEIIKIGDLNVDKIITAEAMGIPLATAISLCTDIPYAI
IRKREYKLDGEIAVHQETGYSKGELYLNGVNKGDKVIIVDDVLSTGGTIIALIEALRKAGAEIKDIICVIERGDGKKIVK
EKTGHTVKTLMKIDVIDGKVVIL

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APT_META3 (A6UX50)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325684.1
- ProteinModelPortal:   A6UX50
- SMR:   A6UX50
- STRING:   A6UX50
- GeneID:   5327519
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1496
- eggNOG:   arNOG05998
- HOGENOM:   HBG496859
- OMA:   TGYSKGE
- ProtClustDB:   PRK02304
- BioCyc:   MAEO419665:MAEO_1496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00004
- InterPro:   IPR005764
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.7

Molecular weight: Translated: 20110; Mature: 20110

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILERSLKTCPIVQRGEYTYFIHPISDGVPLIKPDLIREITTEIIKIGDLNVDKIITAE
CCHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEHH
AMGIPLATAISLCTDIPYAIIRKREYKLDGEIAVHQETGYSKGELYLNGVNKGDKVIIVD
HCCCCHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEE
DVLSTGGTIIALIEALRKAGAEIKDIICVIERGDGKKIVKEKTGHTVKTLMKIDVIDGKV
CHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEEEEECCEE
VIL
EEC
>Mature Secondary Structure
MKILERSLKTCPIVQRGEYTYFIHPISDGVPLIKPDLIREITTEIIKIGDLNVDKIITAE
CCHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEHH
AMGIPLATAISLCTDIPYAIIRKREYKLDGEIAVHQETGYSKGELYLNGVNKGDKVIIVD
HCCCCHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEE
DVLSTGGTIIALIEALRKAGAEIKDIICVIERGDGKKIVKEKTGHTVKTLMKIDVIDGKV
CHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEEEEECCEE
VIL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA