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The map label for this gene is ywlC [H]

Identifier: 150401886

GI number: 150401886

Start: 1525084

End: 1526109

Strand: Direct

Name: ywlC [H]

Synonym: Maeo_1464

Alternate gene names: 150401886

Gene position: 1525084-1526109 (Clockwise)

Preceding gene: 150401883

Following gene: 150401892

Centisome position: 97.17

GC content: 29.82

Gene sequence:

>1026_bases
ATGAAGTTAAAAATATTGAATAAAAATGAAATTGAAATTGCTGCAAATGCCATAAAAGATGGTGATTTAGTAGCATTTCC
TACGGAAACAGTGTATGGATTAGGTGCTGATGCACTAAATCCTGATGCAGTAGAAAAAATTTTTAAAGTTAAAGGGCGAC
CCATCGATAACCCATTAATTATTCATGTAAATAATTTAGAAATGGCAAATAAAATTGCACATATTACAGAAAACGCTAAA
ATATTATTACAAAAGTTTTCACCGGGGCCTTTAACCATTATATTAAAAAAGAAAGAGGTCGTTCCGGCCATAACCTGTGC
TAATTTGGATACAGTTGCCGTTAGAATACCAAATAATAAAATTGCACTGGAATTAATAGAAAAAGCAAATACTCCAATAG
CTGCACCAAGTGCTAATTTATCAGGAAAGCCAAGCCCTACAAATATACAACATATAATAGACGATTTAGGCGATAAAATA
AACTATGCCATAGAGGGGGAAACCACAATAGGTGTAGAATCCACGGTTTTAGATTTAACTGAGAAAAAACCTAAAATATT
AAGATATGGGAGCATAACTTATGAGGATTTAAAAAAAGTTATAGATATTGAATTAATTGAGATTAATAAACAGGGCAAAA
AAATTATAAAAACAGTTAAATCGCCAGGTATGAAATATACGCACTATTCCCCCGATGCACCATTAATAATGGCAACAGGA
AATATTGAAGAAATTACCGGTAAAATAAATGATTTAATAAAAGAATATACTGAAAAAGGAGAGAAAAATGAAAATGTCGG
GATAATTATAACAGAAGAAACAAAAGATAAATATCCTGCAAATATTAAAAAAATAGTATTAGGAAGCAGGTCTGATTTAA
AAACTATCTCTAAAAATTTATTTAATTCATTGAGGGAAATGGATAAAAATGGCGTATCCATTATATTTATTGAAGGATTT
GAAAAAAAAGGACTGGGACTTGCCATAATGGATAGATTAGAAAAAGCATCATCTAAAATAATATAA

Upstream 100 bases:

>100_bases
ATGGAGTATTACGAACAAATATATTATTGTAGGAGCTCCATAATATCACAATATTTAATAATAAAAAATAATAAAAAATA
ATAAAATAAAGTGAAAAAAT

Downstream 100 bases:

>100_bases
AGCAATAACAACAAAATAAAATAAATGGTTAAAAATAATATAATATATTTTTTTATTTTTTATATATATTGATATATCCT
TGATTTAATGTATTATTTAT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKLKILNKNEIEIAANAIKDGDLVAFPTETVYGLGADALNPDAVEKIFKVKGRPIDNPLIIHVNNLEMANKIAHITENAK
ILLQKFSPGPLTIILKKKEVVPAITCANLDTVAVRIPNNKIALELIEKANTPIAAPSANLSGKPSPTNIQHIIDDLGDKI
NYAIEGETTIGVESTVLDLTEKKPKILRYGSITYEDLKKVIDIELIEINKQGKKIIKTVKSPGMKYTHYSPDAPLIMATG
NIEEITGKINDLIKEYTEKGEKNENVGIIITEETKDKYPANIKKIVLGSRSDLKTISKNLFNSLREMDKNGVSIIFIEGF
EKKGLGLAIMDRLEKASSKII

Sequences:

>Translated_341_residues
MKLKILNKNEIEIAANAIKDGDLVAFPTETVYGLGADALNPDAVEKIFKVKGRPIDNPLIIHVNNLEMANKIAHITENAK
ILLQKFSPGPLTIILKKKEVVPAITCANLDTVAVRIPNNKIALELIEKANTPIAAPSANLSGKPSPTNIQHIIDDLGDKI
NYAIEGETTIGVESTVLDLTEKKPKILRYGSITYEDLKKVIDIELIEINKQGKKIIKTVKSPGMKYTHYSPDAPLIMATG
NIEEITGKINDLIKEYTEKGEKNENVGIIITEETKDKYPANIKKIVLGSRSDLKTISKNLFNSLREMDKNGVSIIFIEGF
EKKGLGLAIMDRLEKASSKII
>Mature_341_residues
MKLKILNKNEIEIAANAIKDGDLVAFPTETVYGLGADALNPDAVEKIFKVKGRPIDNPLIIHVNNLEMANKIAHITENAK
ILLQKFSPGPLTIILKKKEVVPAITCANLDTVAVRIPNNKIALELIEKANTPIAAPSANLSGKPSPTNIQHIIDDLGDKI
NYAIEGETTIGVESTVLDLTEKKPKILRYGSITYEDLKKVIDIELIEINKQGKKIIKTVKSPGMKYTHYSPDAPLIMATG
NIEEITGKINDLIKEYTEKGEKNENVGIIITEETKDKYPANIKKIVLGSRSDLKTISKNLFNSLREMDKNGVSIIFIEGF
EKKGLGLAIMDRLEKASSKII

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI2367210, Length=166, Percent_Identity=26.5060240963855, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081864, Length=182, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=377, Percent_Identity=37.1352785145889, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI78707274, Length=187, Percent_Identity=28.8770053475936, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 37528; Mature: 37528

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKILNKNEIEIAANAIKDGDLVAFPTETVYGLGADALNPDAVEKIFKVKGRPIDNPLI
CEEEEECCCCEEEEEEECCCCCEEEECCCHHEECCCCCCCHHHHHHHHHHCCCCCCCCEE
IHVNNLEMANKIAHITENAKILLQKFSPGPLTIILKKKEVVPAITCANLDTVAVRIPNNK
EEECCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCEEEEEECCCC
IALELIEKANTPIAAPSANLSGKPSPTNIQHIIDDLGDKINYAIEGETTIGVESTVLDLT
EEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCEEECCCHHEEECC
EKKPKILRYGSITYEDLKKVIDIELIEINKQGKKIIKTVKSPGMKYTHYSPDAPLIMATG
CCCCCEEEECCCCHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCEEEEEC
NIEEITGKINDLIKEYTEKGEKNENVGIIITEETKDKYPANIKKIVLGSRSDLKTISKNL
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
FNSLREMDKNGVSIIFIEGFEKKGLGLAIMDRLEKASSKII
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLKILNKNEIEIAANAIKDGDLVAFPTETVYGLGADALNPDAVEKIFKVKGRPIDNPLI
CEEEEECCCCEEEEEEECCCCCEEEECCCHHEECCCCCCCHHHHHHHHHHCCCCCCCCEE
IHVNNLEMANKIAHITENAKILLQKFSPGPLTIILKKKEVVPAITCANLDTVAVRIPNNK
EEECCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCEEEEEECCCC
IALELIEKANTPIAAPSANLSGKPSPTNIQHIIDDLGDKINYAIEGETTIGVESTVLDLT
EEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCEEECCCHHEEECC
EKKPKILRYGSITYEDLKKVIDIELIEINKQGKKIIKTVKSPGMKYTHYSPDAPLIMATG
CCCCCEEEECCCCHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCEEEEEC
NIEEITGKINDLIKEYTEKGEKNENVGIIITEETKDKYPANIKKIVLGSRSDLKTISKNL
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
FNSLREMDKNGVSIIFIEGFEKKGLGLAIMDRLEKASSKII
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]