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The map label for this gene is srp54

Identifier: 150401682

GI number: 150401682

Start: 1323401

End: 1324753

Strand: Reverse

Name: srp54

Synonym: Maeo_1260

Alternate gene names: 150401682

Gene position: 1324753-1323401 (Counterclockwise)

Preceding gene: 150401683

Following gene: 150401681

Centisome position: 84.41

GC content: 33.7

Gene sequence:

>1353_bases
ATGCTTGACAAATTAGGTAGCAATATTAATAATGCACTTAGTAAAATAAAAAATGCCACATTTGTAGATAAAAAACTTGT
AAAAGAAGTAATTAAAGACATACAAAAGGCACTTATTCAGGCTGATGTAAATGTTAAACTTGTATTTGCCATGAGTAAAG
AAATTGAAAGAAAGGCGATATATGAATCCGCTCCAAAAGGACTTTCAAAAAAAGACCACATAATTAAAATTGTATATGAT
GAGCTCGTAAAATTACTTGGTGAAGAGGGGCAAAAATTAGAGCTTGACCCAAAAAATAAAAATATAATATTGTTGGTAGG
TATTCAAGGTAGTGGTAAAACTACAAGTGCGGCAAAGTTGGCAAGAACTCTCCAAAAAAGGGGATTTAAACCAGCTTTAA
TTGCTGCGGATGTATATCGACCTGCGGCATATCAGCAATTAAAACAATTATCTGAAAAAATCCACATTCCACTGCATGGT
GACCCTACAAAAACCAAAACTCCTATGGAAATAACAGAAGAAGGGTTAAAACAATTTAAAAAAAATGATGTAATTATAAT
TGATACAGCTGGAAGGCATAAAGAGGAATCGGGATTATTAGAAGAAATGAAAGAAATGAAAGAAAAATTTAATCCTGAAG
AAATAATATTGGTAATAGATGGAACACTTGGTCAACAGGCCAAAAATCAGGCAAAAGCCTTTAAAGACGCCGTTGAAAAC
ATTGGTAGTATTCTCATTACAAAAATGGACGGTTCTGCAAAAGGAGGGGGTGCCCTAAGTGCTGTGGCTGAAATCGGAGC
TCCCATAAAATTCATAGGAACTGGGGAAAAAGTTGATGATTTAGAACCATTTGACCCAAAGAAATTTATTTCAAGATTGC
TTGGAATGGGAGATTTAGATTCCCTACTGGAAAAAACGGAAGATATAATTGATGACGATACAGAGGAAAGCCTTGATGCT
ATGATGAGAGGCAAATTTACATTAAATGAGCTATATTCTCAATTAGAGGCAATATCTAAAATGGGCTCAATGAAGCAATT
GATGGCCATGATACCGGGAATGGGCACAAATCTTCCAAAAGGTGCTGCGGATATTACAGAGCATAAATTAAAAAAATATA
AAATCATAATGGATTCAATGACTTCAACAGAAAAAGAGAATCCCGACATAATAAAAACATCAAGAATGAAAAGAATAGCA
AAAGGGGCAGGAGTTAAACAGGAAGAAATAAAAGAGCTATTGAAATATTATAGCACTACTAAAAATGCCTTCCAAAATAT
GAAAAGTGGGAAAATGCTTAAAATGGGAGGTCCAATGGGCAAAATAATGAGACAATTAATGTATAAAGAATAA

Upstream 100 bases:

>100_bases
GTTATTATATAAATTAGTATATATTATTTTATTTACTATTATTTTATTATATATTCATATTTATTAAATTTATATTAAAT
ATTTATAATTTGGTGGAATT

Downstream 100 bases:

>100_bases
AATAATCACCACATAATAGATTATATCGCAGATATTATTATTCAATTACTATTTTTTATATTTTAATATAATGGGGGACA
TTATGAAAATATTAATTATT

Product: signal recognition particle protein Srp54

Products: NA

Alternate protein names: SRP54

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAIYESAPKGLSKKDHIIKIVYD
ELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKLARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHG
DPTKTKTPMEITEEGLKQFKKNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVEN
IGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLDSLLEKTEDIIDDDTEESLDA
MMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPKGAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIA
KGAGVKQEEIKELLKYYSTTKNAFQNMKSGKMLKMGGPMGKIMRQLMYKE

Sequences:

>Translated_450_residues
MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAIYESAPKGLSKKDHIIKIVYD
ELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKLARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHG
DPTKTKTPMEITEEGLKQFKKNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVEN
IGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLDSLLEKTEDIIDDDTEESLDA
MMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPKGAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIA
KGAGVKQEEIKELLKYYSTTKNAFQNMKSGKMLKMGGPMGKIMRQLMYKE
>Mature_450_residues
MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAIYESAPKGLSKKDHIIKIVYD
ELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKLARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHG
DPTKTKTPMEITEEGLKQFKKNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVEN
IGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLDSLLEKTEDIIDDDTEESLDA
MMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPKGAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIA
KGAGVKQEEIKELLKYYSTTKNAFQNMKSGKMLKMGGPMGKIMRQLMYKE

Specific function: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Homo sapiens, GI4507215, Length=454, Percent_Identity=41.8502202643172, Blast_Score=348, Evalue=6e-96,
Organism=Homo sapiens, GI226371618, Length=401, Percent_Identity=43.3915211970075, Blast_Score=312, Evalue=3e-85,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=48.4276729559748, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI23308697, Length=221, Percent_Identity=26.6968325791855, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI295424842, Length=221, Percent_Identity=26.6968325791855, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788963, Length=422, Percent_Identity=37.2037914691943, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789874, Length=240, Percent_Identity=35.4166666666667, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17539958, Length=470, Percent_Identity=36.1702127659575, Blast_Score=320, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI193206261, Length=212, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=426, Percent_Identity=41.5492957746479, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6320498, Length=238, Percent_Identity=28.9915966386555, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647949, Length=464, Percent_Identity=41.1637931034483, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24641198, Length=216, Percent_Identity=24.0740740740741, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SRP54_META3 (A6UWG4)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325448.1
- ProteinModelPortal:   A6UWG4
- SMR:   A6UWG4
- STRING:   A6UWG4
- GeneID:   5327497
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1260
- eggNOG:   arNOG04631
- HOGENOM:   HBG562580
- OMA:   SKKEHII
- ProtClustDB:   PRK00771
- BioCyc:   MAEO419665:MAEO_1260-MONOMER
- HAMAP:   MF_00306
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004125
- InterPro:   IPR022941
- Gene3D:   G3DSA:1.20.120.140
- Gene3D:   G3DSA:1.10.260.30
- SMART:   SM00382
- SMART:   SM00962
- SMART:   SM00963

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB; SSF47446 Signal_recog_particle_SRP54_M; SSF47364 SRP54

EC number: NA

Molecular weight: Translated: 49935; Mature: 49935

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAI
CCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
YESAPKGLSKKDHIIKIVYDELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCHHHHHH
ARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHGDPTKTKTPMEITEEGLKQFK
HHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHC
KNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVEN
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLD
HHHEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHH
SLLEKTEDIIDDDTEESLDAMMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPK
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIAKGAGVKQEEIKELLKYYSTT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KNAFQNMKSGKMLKMGGPMGKIMRQLMYKE
HHHHHHHCCCCEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAI
CCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
YESAPKGLSKKDHIIKIVYDELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCHHHHHH
ARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHGDPTKTKTPMEITEEGLKQFK
HHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHC
KNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVEN
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLD
HHHEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHH
SLLEKTEDIIDDDTEESLDAMMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPK
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIAKGAGVKQEEIKELLKYYSTT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KNAFQNMKSGKMLKMGGPMGKIMRQLMYKE
HHHHHHHCCCCEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA