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The map label for this gene is ade

Identifier: 150401358

GI number: 150401358

Start: 954748

End: 956538

Strand: Reverse

Name: ade

Synonym: Maeo_0932

Alternate gene names: 150401358

Gene position: 956538-954748 (Counterclockwise)

Preceding gene: 150401359

Following gene: 150401357

Centisome position: 60.95

GC content: 27.53

Gene sequence:

>1791_bases
ATGATAATATTAAAAAATGCCAACATTGTGGGCGTCAGGAACGGAACAATAGTAAATGGAAGTATTGGAATAAATGGGGA
TAAAATAGCTTTTGTGGATTATATTGATTACAACAACCATAATAATGACAATATATATAATAAAAACGAGAACACACAGG
AAATTAGACGAAAACAACGATTCAATACTCGAAGCGAAGCTCCAGTAAAAATAATTGATTTAAAAGGAAAATTCGTATGC
CCCACATTTATTGATGCCCACATACATATAGAATCATCTCATATTACTCCATCAGAATTTGAAAAATATGCCTTAAAATA
TGGCGTATCAAAGGTAATAATAGACCCACACGAAATAGCAAATGTGGTTGGAGTCAATGGTATTAAATTTATGCTAAATG
ATGCGAAATTACTTGATGTTTATTGTATGGTTCCTTCCTGTGTTCCGGCCACAGAATTAGAAACCAATGGAGCTCCAATA
ACTTCAAAAGATATTGAGGAATTATTTAAACAAAATAATTACAGAATATTGGGATTGGGAGAGGTAATGAATTATATTGG
AGTAATAAACAAAGATAAAAATATTATTGATAAAATAAATATGGCTAAAAAATATAATAAACTAATAGATGGACATGCAC
CTCAATTAACAAGGGAGGACTTAATTAATTATGTTAATATGGGCATAATGTCAGACCACGAATGCACAACAGAAGATGAA
GCACTGGAAAAGCTCCAATTGGGATTAAAATTAATGGTTAGAGAGGGGACAGCTTCAAAAAATATATATTTATTAAAAAT
AATTGATATTTTAAAAAGAAAAGGCACATACAATAAATTATTTAAAAATATAATGCTTGTTAGTGATGATATTTCTGTAA
AAGACTTAAAAGAAGGATATTTAATAAATACACTTAAAAAAGCAGTTAAATATGTAAGCCCCATTGAAGCAATTCAAATG
ATTACAATTAATCCAGCAAATTATTTTGGACTTGATATGGAAATAAAACCAGATAATTATGCTGATTTAATCATATTTGA
TGATTTGGAGGAATTTAAAATAAATTCCGTAATTATTAAAGGTAAATTTTTAAATGAATTAAATAAATATAATAAAAATA
ATAATATTAAAAACAATAAAAATAACAATGATAATTTAATAAATAAATCAATAAATTATAATTACAAAACAGAAAATGAT
TTTTTGATTGACGGAATTGATGGGGGGGGAGCTCCCATATCAACCAATTCAAAAGTTAGAATAATTGAGCCAATAGGGAG
CTCCCTTATAACTAATGAAATAATGTTAAATATAGACGATGCTAAAACAAAATTGAAGAATAACGAAATAAATAGAATAT
TCGTTTTAGAAAGACATCGAAATACCAATAAAATAGGAAAAGGACTTATAAAATATTTAAAAACTGGAACAATAGCTTCG
TCTTATGCCCACGATAGCCATAATGTGATAGTTATAGGAAATAATTTAAAAGATATAGCCATTGCCGTTAATCATTTAAA
GGATATGGGAGGAGGATTTGTTGCCGTAAAAGATGGGAAAATAATTGAGCAGGTAAAACTAAATATGGGGGGAATTATGG
GGGCCGATGGAGAATATATTTACAAAAAAATAAATGACATAGAAAATAAGACAAAAAATTGGAGTATAATTGAAAATAAC
AACCTATTTTTATCTATGTCTTTTTTATCTCTTTCAGTAATTCCCAATTTAAAAATAACGGATTTTGGACTAATTAAAAA
TAATAAAATTGTTAATCTGGTGGAATTATGA

Upstream 100 bases:

>100_bases
GATTAAACACAATGACATATATTGATAAATCATATACACGCATAAAATATAATATAAATACTTTTCTATTTTTTTGGATT
TTTAGATTTCTGGTGTAATT

Downstream 100 bases:

>100_bases
TTAAAACAGTAGTTGGAAGTTATCCCGTAGTTAAGGGAGCTCCGCAAAATATAATGGATAAAATAAAAGATAAATTAGGA
ATGTTCGACGAATTTAAATA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQRFNTRSEAPVKIIDLKGKFVC
PTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIANVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPI
TSKDIEELFKQNNYRILGLGEVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDE
ALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGYLINTLKKAVKYVSPIEAIQM
ITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIKGKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTEND
FLIDGIDGGGAPISTNSKVRIIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIAS
SYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYIYKKINDIENKTKNWSIIENN
NLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL

Sequences:

>Translated_596_residues
MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQRFNTRSEAPVKIIDLKGKFVC
PTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIANVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPI
TSKDIEELFKQNNYRILGLGEVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDE
ALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGYLINTLKKAVKYVSPIEAIQM
ITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIKGKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTEND
FLIDGIDGGGAPISTNSKVRIIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIAS
SYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYIYKKINDIENKTKNWSIIENN
NLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL
>Mature_596_residues
MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQRFNTRSEAPVKIIDLKGKFVC
PTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIANVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPI
TSKDIEELFKQNNYRILGLGEVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDE
ALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGYLINTLKKAVKYVSPIEAIQM
ITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIKGKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTEND
FLIDGIDGGGAPISTNSKVRIIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIAS
SYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYIYKKINDIENKTKNWSIIENN
NLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=586, Percent_Identity=29.3515358361775, Blast_Score=240, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_META3 (A6UVJ0)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325124.1
- ProteinModelPortal:   A6UVJ0
- STRING:   A6UVJ0
- GeneID:   5326967
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0932
- eggNOG:   arNOG05049
- HOGENOM:   HBG725357
- OMA:   HIESSHI
- ProtClustDB:   CLSK796877
- BioCyc:   MAEO419665:MAEO_0932-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 67171; Mature: 67171

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQR
CEEEECCCEEEECCCEEEECEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
FNTRSEAPVKIIDLKGKFVCPTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIA
CCCCCCCCEEEEEECCCEECCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECHHHHH
NVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPITSKDIEELFKQNNYRILGLG
HHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHH
EVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDE
HHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHH
ALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGY
HHHHHHHCEEEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHEEEEECCCCHHHHHCCH
LINTLKKAVKYVSPIEAIQMITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIK
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEEE
GKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTENDFLIDGIDGGGAPISTNSKVR
HHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEECCCCEEEECCCCCCCCCCCCCCEE
IIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIAS
EECCCCCCCCCCEEEEEECHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCH
SYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYI
HCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHCCCCEECCCCHHH
YKKINDIENKTKNWSIIENNNLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL
HHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCCEEEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQR
CEEEECCCEEEECCCEEEECEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
FNTRSEAPVKIIDLKGKFVCPTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIA
CCCCCCCCEEEEEECCCEECCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECHHHHH
NVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPITSKDIEELFKQNNYRILGLG
HHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHH
EVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDE
HHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHH
ALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGY
HHHHHHHCEEEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHEEEEECCCCHHHHHCCH
LINTLKKAVKYVSPIEAIQMITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIK
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEEE
GKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTENDFLIDGIDGGGAPISTNSKVR
HHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEECCCCEEEECCCCCCCCCCCCCCEE
IIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIAS
EECCCCCCCCCCEEEEEECHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCH
SYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYI
HCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHCCCCEECCCCHHH
YKKINDIENKTKNWSIIENNNLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL
HHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCCEEEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA