BacMap

Definition	Methanococcus aeolicus Nankai-3, complete genome.
Accession	NC_009635
Length	1,569,500

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The map label for this gene is hflB [C]

Identifier: 150401347

GI number: 150401347

Start: 942444

End: 944615

Strand: Direct

Name: hflB [C]

Synonym: Maeo_0920

Alternate gene names: 150401347

Gene position: 942444-944615 (Clockwise)

Preceding gene: 150401346

Following gene: 150401348

Centisome position: 60.05

GC content: 36.74

Gene sequence:

>2172_bases
ATGGAATTAATAGTAGCTGAGGCATATCAAGGGGATGTGGGTAAAAGCATAGTCCGTATAGACCCCATAACAATGGAAAA
ATTAAATTTAAAATCGGGGGATGTAGTAGAAATTGAAGGAAAAACCAAAAGTTATGCAACGGTTTGGAGAGGATATATGG
AAGACCAAGGAAAGGGAATAATTAGAATGGACGGAATATTAAGACAAAATACAAAAGCTGGAATTGGGGACAAAGTTAAA
ATAAAAAAGACAGAAGTAAAAGAGGCAAAAAAAATAACCCTTGCTCCAATGCAGGAAGTTAGATTTGCTGGGGCATTCAA
TGACCATGTTAAAAGTAGATTAATGGGACAAGTTGTTGGAAAAGGCTCAAAAGTTGTAATAGGGGTACTTGGAACAGCAT
TTCCATTTATAGTGGTAAATACATCCCCAAAAGGGGCTGTAAAAATTACAGAATTTACAGATTTCGACATAAAAACTGAA
CCTGTATCAGAAATAAAAGAATCTAAAATACCAGATATAATTTACGACGATATTGGGGGATTAAAAGAAGAAGTTAAAAA
AATTAGGGAGATGGTGGAGCTCCCTATGAGATACCCAGAATTATTTGATAAATTAGGTATCGAACCACCAAAAGGAGTTT
TACTCGCAGGACCTCCGGGAACAGGTAAAACACTACTTGCAAAAGCCGTAGCTAATGAAGCAGGAGCTAATTTCTATACC
ATAAATGGTCCGGAAATTATGAGTAAATATGTTGGAGAGACAGAAGAAAATTTAAGAAAGATATTTGAAGATGCTGAGGA
AGAAGCTCCAAGTATCATATTCATTGATGAAATTGATAGCGTAGCTCCAAAAAGAGATGAAGCTTCTGGTGAAGTTGAAA
GAAGAATGGTAGCTCAGCTCCTTACGCTGATGGATGGATTAGGCGGAAGAGGACAGGTCGTAGTAATTGCAGCCACAAAT
AGGCCTGACTCATTAGATGGTGCATTAAGAAGACCAGGAAGATTTGATAGAGAATTAACCATTGGTGTTCCAGATAGAAA
AGGTAGAAAAGAAATTCTACAAATACATACAAGAAATATGCCACTCGAAAATGTGGATTTAGACTATTTGGCAGATGTTA
CACATGGTTTTGTTGGTGCTGATTTAGCTTCATTGTGTAAAGAGGCGGCAATGAAAACACTTAGAAGATTACTTCCAGAT
ATTGACTTAGAAAAAGAAGAAATACCTGCGGAAATTCTTGAAAACATTAAAGTAACAATGAAAGACTTTAAAGAAGCTTT
AAAAGAAGTTGAACCATCAGCATTAAGAGAAGTTCTTGTTGAAGTTCCAAATGTGAGATGGGAGGACATTGGAGGATTAG
ATGAGATAAAACAAGACCTCATTGAAGCTGTTGAATGGCCCATAAAAAATAAAGAAGTATTCGAAAAAATGGGAATTCGA
CCACCTAAGGGAGTATTATTATTCGGTCCGCCTGGAACAGGTAAAACCATGCTTGCAAAAGCCGTAGCTAATGAATCACA
AGCTAACTTCATAAGCGTAAAAGGTCCAGAAATATTCTCAAAATGGGTCGGAGAAAGCGAAAAGGCAATCAGAGAAATGT
TTAAAAAAGCAAGACAGGCAGCCCCTACTGTGATATTCTTTGATGAAATTGACAGTATTGCTCCAACAAGAGGTTCAGAT
ATGGGAGGAAGTGGAGTTGCTGAAAAAGTTGTAAATCAACTTTTAACAGAACTTGATGGATTAGAAGAACCAAAAGATGT
TGTAGTTGTTGCAGCTACAAATAGGCCAGATATGCTTGATTCTGCGTTATTGAGGCCAGGGCGATTGGATAGAATTGTGC
TTGTTCCAGTCCCAAATAGTGATGCAAGATACAAAATATTCGAAGTTCATGCCAAAAATATGCCAATAGCCGAAGAAGTA
GATTTAAAGAAACTTGCAGAAGAAACAGAAGGATACACAGGAGCTGACATTGAAGCAATATGTAGGGAAGCTGCAATGAC
AGCACTTAGAGAAAATATAAATGCTGAAAAAGTTGAGTTAAAACACTTTAAGAAGGCAATGAAAAAAATAAGACCATCTG
TTAAAGAAGGAGATATGGCAGTTTATGAAAAATTGGCAAAAGAATACAGTGGAAGCTCCGAGGCTGACGAAGAAGAAAAC
GAAGAAAATTAA

Upstream 100 bases:

>100_bases
TAGGTTGGCATATAATCAATTTAAAATGACAACATTTATAATCAATGAAATTCATAATTATAATAAATTTTATACTAATT
AATAAAAAAAAGGTGGTATT

Downstream 100 bases:

>100_bases
TTAAATAATTAATTTTTCTATTTTCTATTTTCTATTTTTTGATATTTTTCCATTATTTTTAATTTTTATTCTATGGGTAA
TTCTATTTTCACGAATATTT

Product: AAA family ATPase, CDC48 subfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MELIVAEAYQGDVGKSIVRIDPITMEKLNLKSGDVVEIEGKTKSYATVWRGYMEDQGKGIIRMDGILRQNTKAGIGDKVK
IKKTEVKEAKKITLAPMQEVRFAGAFNDHVKSRLMGQVVGKGSKVVIGVLGTAFPFIVVNTSPKGAVKITEFTDFDIKTE
PVSEIKESKIPDIIYDDIGGLKEEVKKIREMVELPMRYPELFDKLGIEPPKGVLLAGPPGTGKTLLAKAVANEAGANFYT
INGPEIMSKYVGETEENLRKIFEDAEEEAPSIIFIDEIDSVAPKRDEASGEVERRMVAQLLTLMDGLGGRGQVVVIAATN
RPDSLDGALRRPGRFDRELTIGVPDRKGRKEILQIHTRNMPLENVDLDYLADVTHGFVGADLASLCKEAAMKTLRRLLPD
IDLEKEEIPAEILENIKVTMKDFKEALKEVEPSALREVLVEVPNVRWEDIGGLDEIKQDLIEAVEWPIKNKEVFEKMGIR
PPKGVLLFGPPGTGKTMLAKAVANESQANFISVKGPEIFSKWVGESEKAIREMFKKARQAAPTVIFFDEIDSIAPTRGSD
MGGSGVAEKVVNQLLTELDGLEEPKDVVVVAATNRPDMLDSALLRPGRLDRIVLVPVPNSDARYKIFEVHAKNMPIAEEV
DLKKLAEETEGYTGADIEAICREAAMTALRENINAEKVELKHFKKAMKKIRPSVKEGDMAVYEKLAKEYSGSSEADEEEN
EEN

Sequences:

>Translated_723_residues
MELIVAEAYQGDVGKSIVRIDPITMEKLNLKSGDVVEIEGKTKSYATVWRGYMEDQGKGIIRMDGILRQNTKAGIGDKVK
IKKTEVKEAKKITLAPMQEVRFAGAFNDHVKSRLMGQVVGKGSKVVIGVLGTAFPFIVVNTSPKGAVKITEFTDFDIKTE
PVSEIKESKIPDIIYDDIGGLKEEVKKIREMVELPMRYPELFDKLGIEPPKGVLLAGPPGTGKTLLAKAVANEAGANFYT
INGPEIMSKYVGETEENLRKIFEDAEEEAPSIIFIDEIDSVAPKRDEASGEVERRMVAQLLTLMDGLGGRGQVVVIAATN
RPDSLDGALRRPGRFDRELTIGVPDRKGRKEILQIHTRNMPLENVDLDYLADVTHGFVGADLASLCKEAAMKTLRRLLPD
IDLEKEEIPAEILENIKVTMKDFKEALKEVEPSALREVLVEVPNVRWEDIGGLDEIKQDLIEAVEWPIKNKEVFEKMGIR
PPKGVLLFGPPGTGKTMLAKAVANESQANFISVKGPEIFSKWVGESEKAIREMFKKARQAAPTVIFFDEIDSIAPTRGSD
MGGSGVAEKVVNQLLTELDGLEEPKDVVVVAATNRPDMLDSALLRPGRLDRIVLVPVPNSDARYKIFEVHAKNMPIAEEV
DLKKLAEETEGYTGADIEAICREAAMTALRENINAEKVELKHFKKAMKKIRPSVKEGDMAVYEKLAKEYSGSSEADEEEN
EEN
>Mature_723_residues
MELIVAEAYQGDVGKSIVRIDPITMEKLNLKSGDVVEIEGKTKSYATVWRGYMEDQGKGIIRMDGILRQNTKAGIGDKVK
IKKTEVKEAKKITLAPMQEVRFAGAFNDHVKSRLMGQVVGKGSKVVIGVLGTAFPFIVVNTSPKGAVKITEFTDFDIKTE
PVSEIKESKIPDIIYDDIGGLKEEVKKIREMVELPMRYPELFDKLGIEPPKGVLLAGPPGTGKTLLAKAVANEAGANFYT
INGPEIMSKYVGETEENLRKIFEDAEEEAPSIIFIDEIDSVAPKRDEASGEVERRMVAQLLTLMDGLGGRGQVVVIAATN
RPDSLDGALRRPGRFDRELTIGVPDRKGRKEILQIHTRNMPLENVDLDYLADVTHGFVGADLASLCKEAAMKTLRRLLPD
IDLEKEEIPAEILENIKVTMKDFKEALKEVEPSALREVLVEVPNVRWEDIGGLDEIKQDLIEAVEWPIKNKEVFEKMGIR
PPKGVLLFGPPGTGKTMLAKAVANESQANFISVKGPEIFSKWVGESEKAIREMFKKARQAAPTVIFFDEIDSIAPTRGSD
MGGSGVAEKVVNQLLTELDGLEEPKDVVVVAATNRPDMLDSALLRPGRLDRIVLVPVPNSDARYKIFEVHAKNMPIAEEV
DLKKLAEETEGYTGADIEAICREAAMTALRENINAEKVELKHFKKAMKKIRPSVKEGDMAVYEKLAKEYSGSSEADEEEN
EEN

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=742, Percent_Identity=47.3045822102426, Blast_Score=659, Evalue=0.0,
Organism=Homo sapiens, GI157671927, Length=545, Percent_Identity=53.7614678899083, Blast_Score=609, Evalue=1e-174,
Organism=Homo sapiens, GI45643125, Length=603, Percent_Identity=44.7761194029851, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI45643123, Length=603, Percent_Identity=44.7761194029851, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI229577436, Length=745, Percent_Identity=39.4630872483221, Blast_Score=491, Evalue=1e-138,
Organism=Homo sapiens, GI4505725, Length=480, Percent_Identity=36.6666666666667, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI194018488, Length=523, Percent_Identity=33.8432122370937, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI24497618, Length=274, Percent_Identity=46.3503649635037, Blast_Score=258, Evalue=2e-68,
Organism=Homo sapiens, GI153792536, Length=274, Percent_Identity=45.985401459854, Blast_Score=256, Evalue=8e-68,
Organism=Homo sapiens, GI24497435, Length=309, Percent_Identity=40.7766990291262, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI24430151, Length=256, Percent_Identity=44.53125, Blast_Score=229, Evalue=9e-60,
Organism=Homo sapiens, GI21361144, Length=231, Percent_Identity=44.5887445887446, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI24430155, Length=282, Percent_Identity=41.8439716312057, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI5729991, Length=282, Percent_Identity=41.8439716312057, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI89064750, Length=282, Percent_Identity=41.8439716312057, Blast_Score=220, Evalue=4e-57,
Organism=Homo sapiens, GI4506209, Length=296, Percent_Identity=40.2027027027027, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI195539395, Length=270, Percent_Identity=42.5925925925926, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI300192933, Length=259, Percent_Identity=39.7683397683398, Blast_Score=203, Evalue=5e-52,
Organism=Homo sapiens, GI5901990, Length=312, Percent_Identity=40.3846153846154, Blast_Score=201, Evalue=3e-51,
Organism=Homo sapiens, GI4507173, Length=250, Percent_Identity=41.6, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI226371754, Length=258, Percent_Identity=40.6976744186046, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI14149767, Length=315, Percent_Identity=39.3650793650794, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI62177112, Length=315, Percent_Identity=39.3650793650794, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI31742536, Length=303, Percent_Identity=35.6435643564356, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI112789543, Length=303, Percent_Identity=35.6435643564356, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI156564401, Length=403, Percent_Identity=35.4838709677419, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI7019569, Length=278, Percent_Identity=38.8489208633094, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI310125280, Length=246, Percent_Identity=41.0569105691057, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI17865802, Length=252, Percent_Identity=40.4761904761905, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI7657689, Length=253, Percent_Identity=40.7114624505929, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI21327685, Length=253, Percent_Identity=40.7114624505929, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI310125282, Length=246, Percent_Identity=41.0569105691057, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI31377644, Length=268, Percent_Identity=37.3134328358209, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI11875211, Length=284, Percent_Identity=38.7323943661972, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI40806170, Length=284, Percent_Identity=38.7323943661972, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI64084766, Length=289, Percent_Identity=30.7958477508651, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI116292174, Length=284, Percent_Identity=29.2253521126761, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI40806173, Length=139, Percent_Identity=41.726618705036, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI11321607, Length=199, Percent_Identity=29.1457286432161, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI40255052, Length=251, Percent_Identity=23.9043824701195, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1789568, Length=270, Percent_Identity=41.4814814814815, Blast_Score=212, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17532375, Length=751, Percent_Identity=44.8735019973369, Blast_Score=656, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17531535, Length=747, Percent_Identity=44.8460508701473, Blast_Score=641, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17537217, Length=616, Percent_Identity=38.1493506493507, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17508053, Length=531, Percent_Identity=39.7363465160075, Blast_Score=349, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI193206116, Length=275, Percent_Identity=46.9090909090909, Blast_Score=252, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI133931034, Length=275, Percent_Identity=46.9090909090909, Blast_Score=251, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI193206114, Length=275, Percent_Identity=46.9090909090909, Blast_Score=251, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI25144281, Length=337, Percent_Identity=39.1691394658754, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI25144278, Length=337, Percent_Identity=39.1691394658754, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17554786, Length=275, Percent_Identity=42.1818181818182, Blast_Score=231, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17562804, Length=494, Percent_Identity=32.7935222672065, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17563250, Length=260, Percent_Identity=42.3076923076923, Blast_Score=226, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17508701, Length=233, Percent_Identity=44.206008583691, Blast_Score=223, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71987372, Length=275, Percent_Identity=41.4545454545455, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71987364, Length=275, Percent_Identity=41.4545454545455, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=230, Percent_Identity=47.8260869565217, Blast_Score=215, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI25153574, Length=491, Percent_Identity=31.1608961303462, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=43.0278884462151, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17505546, Length=270, Percent_Identity=39.6296296296296, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=44, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71994521, Length=253, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25146157, Length=276, Percent_Identity=39.1304347826087, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17554264, Length=238, Percent_Identity=41.5966386554622, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI133901662, Length=407, Percent_Identity=34.8894348894349, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI86561515, Length=282, Percent_Identity=37.5886524822695, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI133901658, Length=407, Percent_Identity=34.8894348894349, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI115534323, Length=232, Percent_Identity=40.948275862069, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17508421, Length=267, Percent_Identity=38.5767790262172, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563584, Length=270, Percent_Identity=38.1481481481481, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17560432, Length=269, Percent_Identity=40.5204460966543, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17541224, Length=219, Percent_Identity=38.8127853881278, Blast_Score=159, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17541226, Length=219, Percent_Identity=38.8127853881278, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=98, Percent_Identity=44.8979591836735, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566590, Length=98, Percent_Identity=44.8979591836735, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17533043, Length=160, Percent_Identity=30.625, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71990294, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320077, Length=755, Percent_Identity=47.2847682119205, Blast_Score=664, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323429, Length=547, Percent_Identity=51.5539305301645, Blast_Score=560, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6322994, Length=653, Percent_Identity=38.1316998468606, Blast_Score=445, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321709, Length=433, Percent_Identity=36.7205542725173, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6324000, Length=523, Percent_Identity=30.5927342256214, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6322651, Length=501, Percent_Identity=32.5349301397206, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=44.8979591836735, Blast_Score=230, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6320197, Length=283, Percent_Identity=44.8763250883392, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320602, Length=234, Percent_Identity=47.008547008547, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6322704, Length=230, Percent_Identity=46.9565217391304, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324833, Length=280, Percent_Identity=41.0714285714286, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=240, Percent_Identity=41.25, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323736, Length=250, Percent_Identity=43.6, Blast_Score=206, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6320854, Length=256, Percent_Identity=41.796875, Blast_Score=200, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6325431, Length=315, Percent_Identity=34.9206349206349, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6321465, Length=236, Percent_Identity=43.6440677966102, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6325281, Length=257, Percent_Identity=39.6887159533074, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6319554, Length=412, Percent_Identity=34.9514563106796, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6325183, Length=298, Percent_Identity=35.5704697986577, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320887, Length=351, Percent_Identity=33.9031339031339, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI9755327, Length=279, Percent_Identity=28.673835125448, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320583, Length=324, Percent_Identity=26.2345679012346, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137560, Length=744, Percent_Identity=45.6989247311828, Blast_Score=655, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076486, Length=744, Percent_Identity=45.6989247311828, Blast_Score=654, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076488, Length=722, Percent_Identity=45.983379501385, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921202, Length=595, Percent_Identity=38.655462184874, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI45552965, Length=307, Percent_Identity=47.8827361563518, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI281365776, Length=307, Percent_Identity=47.8827361563518, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24660075, Length=307, Percent_Identity=47.8827361563518, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24656825, Length=521, Percent_Identity=33.9731285988484, Blast_Score=292, Evalue=7e-79,
Organism=Drosophila melanogaster, GI21355121, Length=626, Percent_Identity=31.9488817891374, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24656820, Length=540, Percent_Identity=32.7777777777778, Blast_Score=285, Evalue=1e-76,
Organism=Drosophila melanogaster, GI281363136, Length=593, Percent_Identity=31.7032040472175, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI78707192, Length=593, Percent_Identity=31.7032040472175, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24652279, Length=259, Percent_Identity=45.5598455598456, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24651451, Length=306, Percent_Identity=39.8692810457516, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI19920408, Length=307, Percent_Identity=40.0651465798046, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24649446, Length=346, Percent_Identity=38.150289017341, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI281361487, Length=253, Percent_Identity=44.2687747035573, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17738151, Length=236, Percent_Identity=44.0677966101695, Blast_Score=227, Evalue=3e-59,
Organism=Drosophila melanogaster, GI18860063, Length=233, Percent_Identity=45.4935622317597, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI17137738, Length=265, Percent_Identity=45.2830188679245, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24663015, Length=265, Percent_Identity=43.0188679245283, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24640100, Length=265, Percent_Identity=42.2641509433962, Blast_Score=213, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24665814, Length=249, Percent_Identity=42.9718875502008, Blast_Score=209, Evalue=8e-54,
Organism=Drosophila melanogaster, GI28574878, Length=249, Percent_Identity=42.9718875502008, Blast_Score=209, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24658770, Length=247, Percent_Identity=44.5344129554656, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24644145, Length=297, Percent_Identity=40.7407407407407, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI281360146, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI281360138, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI281360142, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI21357333, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24581396, Length=287, Percent_Identity=39.0243902439024, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI281360144, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI281360140, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI281360136, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24644411, Length=294, Percent_Identity=37.0748299319728, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18859657, Length=251, Percent_Identity=42.2310756972112, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24639391, Length=252, Percent_Identity=40.4761904761905, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17864540, Length=414, Percent_Identity=34.7826086956522, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28573010, Length=400, Percent_Identity=34.75, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28571849, Length=305, Percent_Identity=36.3934426229508, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI28571847, Length=305, Percent_Identity=36.3934426229508, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI20129423, Length=277, Percent_Identity=35.3790613718412, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI20129529, Length=314, Percent_Identity=34.0764331210191, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24639486, Length=269, Percent_Identity=34.2007434944238, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=40.9638554216867, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28573181, Length=238, Percent_Identity=27.7310924369748, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20129417, Length=159, Percent_Identity=31.4465408805031, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583262, Length=159, Percent_Identity=31.4465408805031, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR001984
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 79893; Mature: 79893

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIVAEAYQGDVGKSIVRIDPITMEKLNLKSGDVVEIEGKTKSYATVWRGYMEDQGKGI
CCEEEEECCCCCCCCCEEEECCEEHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCE
IRMDGILRQNTKAGIGDKVKIKKTEVKEAKKITLAPMQEVRFAGAFNDHVKSRLMGQVVG
EEECCHHHCCCCCCCCCCEEEEHHHHHHHHHEECCCHHHHHHHCCHHHHHHHHHHHHHHC
KGSKVVIGVLGTAFPFIVVNTSPKGAVKITEFTDFDIKTEPVSEIKESKIPDIIYDDIGG
CCCEEEEEECCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHCC
LKEEVKKIREMVELPMRYPELFDKLGIEPPKGVLLAGPPGTGKTLLAKAVANEAGANFYT
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEE
INGPEIMSKYVGETEENLRKIFEDAEEEAPSIIFIDEIDSVAPKRDEASGEVERRMVAQL
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LTLMDGLGGRGQVVVIAATNRPDSLDGALRRPGRFDRELTIGVPDRKGRKEILQIHTRNM
HHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCC
PLENVDLDYLADVTHGFVGADLASLCKEAAMKTLRRLLPDIDLEKEEIPAEILENIKVTM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHH
KDFKEALKEVEPSALREVLVEVPNVRWEDIGGLDEIKQDLIEAVEWPIKNKEVFEKMGIR
HHHHHHHHHCCHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
PPKGVLLFGPPGTGKTMLAKAVANESQANFISVKGPEIFSKWVGESEKAIREMFKKARQA
CCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHC
APTVIFFDEIDSIAPTRGSDMGGSGVAEKVVNQLLTELDGLEEPKDVVVVAATNRPDMLD
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
SALLRPGRLDRIVLVPVPNSDARYKIFEVHAKNMPIAEEVDLKKLAEETEGYTGADIEAI
HHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
CREAAMTALRENINAEKVELKHFKKAMKKIRPSVKEGDMAVYEKLAKEYSGSSEADEEEN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
EEN
CCC
>Mature Secondary Structure
MELIVAEAYQGDVGKSIVRIDPITMEKLNLKSGDVVEIEGKTKSYATVWRGYMEDQGKGI
CCEEEEECCCCCCCCCEEEECCEEHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCE
IRMDGILRQNTKAGIGDKVKIKKTEVKEAKKITLAPMQEVRFAGAFNDHVKSRLMGQVVG
EEECCHHHCCCCCCCCCCEEEEHHHHHHHHHEECCCHHHHHHHCCHHHHHHHHHHHHHHC
KGSKVVIGVLGTAFPFIVVNTSPKGAVKITEFTDFDIKTEPVSEIKESKIPDIIYDDIGG
CCCEEEEEECCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHCC
LKEEVKKIREMVELPMRYPELFDKLGIEPPKGVLLAGPPGTGKTLLAKAVANEAGANFYT
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEE
INGPEIMSKYVGETEENLRKIFEDAEEEAPSIIFIDEIDSVAPKRDEASGEVERRMVAQL
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LTLMDGLGGRGQVVVIAATNRPDSLDGALRRPGRFDRELTIGVPDRKGRKEILQIHTRNM
HHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCC
PLENVDLDYLADVTHGFVGADLASLCKEAAMKTLRRLLPDIDLEKEEIPAEILENIKVTM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHH
KDFKEALKEVEPSALREVLVEVPNVRWEDIGGLDEIKQDLIEAVEWPIKNKEVFEKMGIR
HHHHHHHHHCCHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
PPKGVLLFGPPGTGKTMLAKAVANESQANFISVKGPEIFSKWVGESEKAIREMFKKARQA
CCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHC
APTVIFFDEIDSIAPTRGSDMGGSGVAEKVVNQLLTELDGLEEPKDVVVVAATNRPDMLD
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
SALLRPGRLDRIVLVPVPNSDARYKIFEVHAKNMPIAEEVDLKKLAEETEGYTGADIEAI
HHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
CREAAMTALRENINAEKVELKHFKKAMKKIRPSVKEGDMAVYEKLAKEYSGSSEADEEEN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
EEN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]