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The map label for this gene is yggV [C]

Identifier: 150401265

GI number: 150401265

Start: 866501

End: 867082

Strand: Direct

Name: yggV [C]

Synonym: Maeo_0837

Alternate gene names: 150401265

Gene position: 866501-867082 (Clockwise)

Preceding gene: 150401264

Following gene: 150401267

Centisome position: 55.21

GC content: 26.63

Gene sequence:

>582_bases
ATGAAAATTTATTTCGCAACTGGAAATCAGCACAAAATTAAAGAAGCAAATATTATACTACAAGATTTAAAAAATAAAAA
TATATCTATCGAACAGATAACGATGCCATATCCTGAAATTCAAGGGACATTGGAAGAAGTTTCGATATTTGGAGCAAAAT
ATATTTATGATACCATAAAAAAACCGATAATTGTAGAGGATAGTGGATTTTTTGTAGATTCACTTAATGGTTTTCCTTCA
ACATATTCAAAATTTGTGCAAGAAACCATTGGAAATAAAGGAATTTTAAAGCTATTGGAAGATAAAAATAACGAAAAAAA
TGAAAACAATAGAAGTGCATATTTTAAAACAGTTATTGGATATTGTGATGAAAATGGAATTAAATTATTCCGGGGAATTG
TAAAAGGAAAGGTATCTAATGAAATAAAAAGTAAAGGTTATGGATTTGCATATGATAGTATTTTTATCCCCGATGGAGAA
AATAGAACATTTGCAGAAATGAAAACAGAGGAAAAAAGCAATATTTCCCATAGAAAAAAAGCATTTGAGGAATTTAAAAA
ATTTTTAAATGATGTATTTTGA

Upstream 100 bases:

>100_bases
GAATTGGAGAAGAGACGGCACATCAGCCCAATGAACATATAAAACTTAATGATTTAATAAAAATGGCTAAAATATATTAT
GAAATTATGGAGGGATTTAA

Downstream 100 bases:

>100_bases
AACTAATTATTTATACTATTTAATATATTAATTTTTTTCCATTTCCAACCGTTATTGGTATAATTTATTTCAAATATATC
TCCTTCATTAATTTTATAGC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKIYFATGNQHKIKEANIILQDLKNKNISIEQITMPYPEIQGTLEEVSIFGAKYIYDTIKKPIIVEDSGFFVDSLNGFPS
TYSKFVQETIGNKGILKLLEDKNNEKNENNRSAYFKTVIGYCDENGIKLFRGIVKGKVSNEIKSKGYGFAYDSIFIPDGE
NRTFAEMKTEEKSNISHRKKAFEEFKKFLNDVF

Sequences:

>Translated_193_residues
MKIYFATGNQHKIKEANIILQDLKNKNISIEQITMPYPEIQGTLEEVSIFGAKYIYDTIKKPIIVEDSGFFVDSLNGFPS
TYSKFVQETIGNKGILKLLEDKNNEKNENNRSAYFKTVIGYCDENGIKLFRGIVKGKVSNEIKSKGYGFAYDSIFIPDGE
NRTFAEMKTEEKSNISHRKKAFEEFKKFLNDVF
>Mature_193_residues
MKIYFATGNQHKIKEANIILQDLKNKNISIEQITMPYPEIQGTLEEVSIFGAKYIYDTIKKPIIVEDSGFFVDSLNGFPS
TYSKFVQETIGNKGILKLLEDKNNEKNENNRSAYFKTVIGYCDENGIKLFRGIVKGKVSNEIKSKGYGFAYDSIFIPDGE
NRTFAEMKTEEKSNISHRKKAFEEFKKFLNDVF

Specific function: Hydrolyzes non-standard nucleotides such as XTP and ITP to nucleotide monophosphate and pyrophosphate. Probably excludes non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=194, Percent_Identity=29.3814432989691, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI31657144, Length=183, Percent_Identity=27.3224043715847, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556833, Length=193, Percent_Identity=27.979274611399, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322529, Length=197, Percent_Identity=36.0406091370558, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19920712, Length=187, Percent_Identity=30.4812834224599, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22159; Mature: 22159

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYFATGNQHKIKEANIILQDLKNKNISIEQITMPYPEIQGTLEEVSIFGAKYIYDTIK
CEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
KPIIVEDSGFFVDSLNGFPSTYSKFVQETIGNKGILKLLEDKNNEKNENNRSAYFKTVIG
CCEEEECCCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YCDENGIKLFRGIVKGKVSNEIKSKGYGFAYDSIFIPDGENRTFAEMKTEEKSNISHRKK
HCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECEEEECCCCCCCHHHHHHHHHHHHHHHHH
AFEEFKKFLNDVF
HHHHHHHHHHHCC
>Mature Secondary Structure
MKIYFATGNQHKIKEANIILQDLKNKNISIEQITMPYPEIQGTLEEVSIFGAKYIYDTIK
CEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
KPIIVEDSGFFVDSLNGFPSTYSKFVQETIGNKGILKLLEDKNNEKNENNRSAYFKTVIG
CCEEEECCCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YCDENGIKLFRGIVKGKVSNEIKSKGYGFAYDSIFIPDGENRTFAEMKTEEKSNISHRKK
HCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECEEEECCCCCCCHHHHHHHHHHHHHHHHH
AFEEFKKFLNDVF
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10404228 [H]