Click here to switch to the map view.

The map label for this gene is cbiH [H]

Identifier: 150401259

GI number: 150401259

Start: 860644

End: 861399

Strand: Direct

Name: cbiH [H]

Synonym: Maeo_0830

Alternate gene names: 150401259

Gene position: 860644-861399 (Clockwise)

Preceding gene: 150401258

Following gene: 150401261

Centisome position: 54.84

GC content: 27.12

Gene sequence:

>756_bases
ATGCTATATATTGTTGGAATAGGTCCGGGAAATAAAGAATATTTTACGGAACAGGCTGAATCTGTTTTAAATTCCGTTGA
TTCAATTGTATGCTATAAAGGATATGAAAAATTTATAAAAAGATTTAATAAACCAATTTACACATCAGGAATGAAAAAAG
AAATAGATAGAGTGGATTATGCACTAAAAGAAGCAAAAAATAAAAATATAGCATTGGTATCAAGTGGAGATGCCACAATA
TATGGAATGGCTTCACTATCCTATGAATTAAATAATAAAAATAACTATAATGTTGATATAGAGGTAATAAGTGGCTTAAC
TTCTGCAAGTTTATGCTCTGCAATATTGGGAGCTCCATTAAATCATGACTTCGCCGTTATTAGTTTAAGTGATTTATTAA
CTCCATTAGACATCATATTAAAAAGAGTTAATAGTTTATTAATGGGAGATTTTGTTATTGCCATATATAATCCACTTAGT
AAATCCAGAAAAGAGCCATTTTTAAAGTGCTTTGAAATAATACAAAATCATTCCAAACAAAATAATTTAAATTTGGTTGT
AGGAATTGTAAAAAATGCAGGAAGAGATAACGAAGAATATAAAATGACCACAATAAACGATTTAATGGATAATTTAGAGG
AATACATGAAATATATTGATATGAATACAACCATAATAGTTGGGAGCTCCAACACAAAAATAATAAACAATAAAATGATT
ACTCCAAGAGGGTATTTAAATAAATATTTAAAATAA

Upstream 100 bases:

>100_bases
TTTTTGTTTCAGGATGACGACATCAGCACTATCTGACGCAGCTACCAAAACAAAACGATGAATATTATTTTTTTAATTTT
ATAATTTTATGTGTGATATT

Downstream 100 bases:

>100_bases
TTGGGAGCTCCTTTAATATATAAATATATATTTTTTATTATTATTCTACGGTTATTTCATATCTTACTGTTTTAACCATG
CTATCGCTTTCCCATAGGTT

Product: precorrin-3B C17-methyltransferase

Products: S-adenosyl-L-homocysteine; Precorrin 4

Alternate protein names: Cobalt-precorrin-3 methylase; Cobalt-precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLYIVGIGPGNKEYFTEQAESVLNSVDSIVCYKGYEKFIKRFNKPIYTSGMKKEIDRVDYALKEAKNKNIALVSSGDATI
YGMASLSYELNNKNNYNVDIEVISGLTSASLCSAILGAPLNHDFAVISLSDLLTPLDIILKRVNSLLMGDFVIAIYNPLS
KSRKEPFLKCFEIIQNHSKQNNLNLVVGIVKNAGRDNEEYKMTTINDLMDNLEEYMKYIDMNTTIIVGSSNTKIINNKMI
TPRGYLNKYLK

Sequences:

>Translated_251_residues
MLYIVGIGPGNKEYFTEQAESVLNSVDSIVCYKGYEKFIKRFNKPIYTSGMKKEIDRVDYALKEAKNKNIALVSSGDATI
YGMASLSYELNNKNNYNVDIEVISGLTSASLCSAILGAPLNHDFAVISLSDLLTPLDIILKRVNSLLMGDFVIAIYNPLS
KSRKEPFLKCFEIIQNHSKQNNLNLVVGIVKNAGRDNEEYKMTTINDLMDNLEEYMKYIDMNTTIIVGSSNTKIINNKMI
TPRGYLNKYLK
>Mature_251_residues
MLYIVGIGPGNKEYFTEQAESVLNSVDSIVCYKGYEKFIKRFNKPIYTSGMKKEIDRVDYALKEAKNKNIALVSSGDATI
YGMASLSYELNNKNNYNVDIEVISGLTSASLCSAILGAPLNHDFAVISLSDLLTPLDIILKRVNSLLMGDFVIAIYNPLS
KSRKEPFLKCFEIIQNHSKQNNLNLVVGIVKNAGRDNEEYKMTTINDLMDNLEEYMKYIDMNTTIIVGSSNTKIINNKMI
TPRGYLNKYLK

Specific function: Methyltransferase that catalyzes the methylation of C-17 in cobalt-precorrin-3B to form cobalt-precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: 2.1.1.131

Molecular weight: Translated: 28244; Mature: 28244

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIVGIGPGNKEYFTEQAESVLNSVDSIVCYKGYEKFIKRFNKPIYTSGMKKEIDRVDY
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALKEAKNKNIALVSSGDATIYGMASLSYELNNKNNYNVDIEVISGLTSASLCSAILGAPL
HHHHCCCCCEEEEECCCEEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCC
NHDFAVISLSDLLTPLDIILKRVNSLLMGDFVIAIYNPLSKSRKEPFLKCFEIIQNHSKQ
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCCCC
NNLNLVVGIVKNAGRDNEEYKMTTINDLMDNLEEYMKYIDMNTTIIVGSSNTKIINNKMI
CCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
TPRGYLNKYLK
CCHHHHHHHCC
>Mature Secondary Structure
MLYIVGIGPGNKEYFTEQAESVLNSVDSIVCYKGYEKFIKRFNKPIYTSGMKKEIDRVDY
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALKEAKNKNIALVSSGDATIYGMASLSYELNNKNNYNVDIEVISGLTSASLCSAILGAPL
HHHHCCCCCEEEEECCCEEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCC
NHDFAVISLSDLLTPLDIILKRVNSLLMGDFVIAIYNPLSKSRKEPFLKCFEIIQNHSKQ
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCCCC
NNLNLVVGIVKNAGRDNEEYKMTTINDLMDNLEEYMKYIDMNTTIIVGSSNTKIINNKMI
CCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
TPRGYLNKYLK
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 3B

Specific reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin-4

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]