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The map label for this gene is era [C]

Identifier: 150401230

GI number: 150401230

Start: 828884

End: 829900

Strand: Direct

Name: era [C]

Synonym: Maeo_0801

Alternate gene names: 150401230

Gene position: 828884-829900 (Clockwise)

Preceding gene: 150401229

Following gene: 150401237

Centisome position: 52.81

GC content: 30.97

Gene sequence:

>1017_bases
ATGAAAAAAAGAGTAGAAGCGAACCCATTTAGAAAAATACCTACAATATTATATGCGGATGAACTATTAGACAAAGCACA
TAATAGAGCTGAAAAAGTTGCAGGTGAGTTAAGAAAAACCACAAGAGGAGAAAGTTTATATAAATCGAGAATAATCGAAG
AGCAAAAAATAAGAGCTACTACGGCCGTTATATCCGACTATTTATCAACCGTTGTAAAAAAAACTCCTTCCGTGGATAAT
TTAGACCCATTTTATAGGGAAATTCTTGAAATATTAATCGATACAGATGATTTTAAAAAATCTTTGGGGGCCCTAAACTG
GGCATCAGATTTCTCCAAAAAATTAGGTTCTATGTATGGTAGAAGGGTACATAAAGCAGGGTCTGCAAGACATACTTCAA
TAATTAGAAAACAATTTAACGGTAGAATATCTTCTGTTGTAAAGCAAATTTATCCAAATTTAGCATGTATTGCAGTTGCA
AGAGAAAAATTAAAGAATCTACCAACTGTTAAAGATATGCCTACGGTAGTTATAGCAGGATACCCCAATGTAGGAAAATC
CACATTATTAAGAAAATTAACAAATGCAGAGCCTGAAATAAATGCATATCCATTCACAACAAAAGGATTAAATGTTGGTT
ATTCGGATTATGGAATACAATTTGTAGATACTCCCGGAGTATTGGATAGACCAATTTATGAGAGAAATGATATAGAGCTA
CATGCAGTTGTGGCTTTGAACTATCTCGCAGATTTAATTGTTTTTGTGATGGACCCAACAGAATATTGTGGTTATACCAT
TGAAGAGCAAATCAATTTAACAAACGAAATTGAAAAAACCTTCAAAGTGCCAATAATAATCATAATAAATAAAATAGATA
TTGAAGGATATGAAGAAAATCTTAAAATAGCAGAACGGGAATTAAGTAGTAAATTCGATATAATACGAGCATCAACTGAA
AACGATATAAATATTGATGTAATTAAAAAAGAAATTATGAATAAAATAGATTTATAA

Upstream 100 bases:

>100_bases
CTATTTTTTTATGATAATTTAACTATAATGAATAATAATAAAATAAGTAAATAATTATGTAAAAAATAATTTATAAAAAT
TTACAAATTTTGGTGAGACA

Downstream 100 bases:

>100_bases
TTATTCATTATATTATTTAGTATATCCGGTGTATTATTTTTTATATTTTATTATATATTTATCTTTTTTATCGTTATCCT
TTTAACTATGTCAGTTATGA

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKRVEANPFRKIPTILYADELLDKAHNRAEKVAGELRKTTRGESLYKSRIIEEQKIRATTAVISDYLSTVVKKTPSVDN
LDPFYREILEILIDTDDFKKSLGALNWASDFSKKLGSMYGRRVHKAGSARHTSIIRKQFNGRISSVVKQIYPNLACIAVA
REKLKNLPTVKDMPTVVIAGYPNVGKSTLLRKLTNAEPEINAYPFTTKGLNVGYSDYGIQFVDTPGVLDRPIYERNDIEL
HAVVALNYLADLIVFVMDPTEYCGYTIEEQINLTNEIEKTFKVPIIIIINKIDIEGYEENLKIAERELSSKFDIIRASTE
NDINIDVIKKEIMNKIDL

Sequences:

>Translated_338_residues
MKKRVEANPFRKIPTILYADELLDKAHNRAEKVAGELRKTTRGESLYKSRIIEEQKIRATTAVISDYLSTVVKKTPSVDN
LDPFYREILEILIDTDDFKKSLGALNWASDFSKKLGSMYGRRVHKAGSARHTSIIRKQFNGRISSVVKQIYPNLACIAVA
REKLKNLPTVKDMPTVVIAGYPNVGKSTLLRKLTNAEPEINAYPFTTKGLNVGYSDYGIQFVDTPGVLDRPIYERNDIEL
HAVVALNYLADLIVFVMDPTEYCGYTIEEQINLTNEIEKTFKVPIIIIINKIDIEGYEENLKIAERELSSKFDIIRASTE
NDINIDVIKKEIMNKIDL
>Mature_338_residues
MKKRVEANPFRKIPTILYADELLDKAHNRAEKVAGELRKTTRGESLYKSRIIEEQKIRATTAVISDYLSTVVKKTPSVDN
LDPFYREILEILIDTDDFKKSLGALNWASDFSKKLGSMYGRRVHKAGSARHTSIIRKQFNGRISSVVKQIYPNLACIAVA
REKLKNLPTVKDMPTVVIAGYPNVGKSTLLRKLTNAEPEINAYPFTTKGLNVGYSDYGIQFVDTPGVLDRPIYERNDIEL
HAVVALNYLADLIVFVMDPTEYCGYTIEEQINLTNEIEKTFKVPIIIIINKIDIEGYEENLKIAERELSSKFDIIRASTE
NDINIDVIKKEIMNKIDL

Specific function: Binds Both GDP And GTP, Has An Intrinsic GTPase Activity And Is Essential For Cell Growth. [C]

COG id: COG1084

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP1/OBG family. NOG subfamily [H]

Homologues:

Organism=Homo sapiens, GI55953087, Length=336, Percent_Identity=30.952380952381, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI25145602, Length=290, Percent_Identity=32.0689655172414, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25145600, Length=290, Percent_Identity=32.0689655172414, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325164, Length=290, Percent_Identity=31.3793103448276, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI19921908, Length=294, Percent_Identity=35.0340136054422, Blast_Score=184, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006073
- InterPro:   IPR010674
- InterPro:   IPR005225 [H]

Pfam domain/function: PF06858 NOG1 [H]

EC number: NA

Molecular weight: Translated: 38391; Mature: 38391

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVEANPFRKIPTILYADELLDKAHNRAEKVAGELRKTTRGESLYKSRIIEEQKIRAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAVISDYLSTVVKKTPSVDNLDPFYREILEILIDTDDFKKSLGALNWASDFSKKLGSMYG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRVHKAGSARHTSIIRKQFNGRISSVVKQIYPNLACIAVAREKLKNLPTVKDMPTVVIAG
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEC
YPNVGKSTLLRKLTNAEPEINAYPFTTKGLNVGYSDYGIQFVDTPGVLDRPIYERNDIEL
CCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
HAVVALNYLADLIVFVMDPTEYCGYTIEEQINLTNEIEKTFKVPIIIIINKIDIEGYEEN
HHHHHHHHHHHHHHHHCCCHHHCCEEHHHHCCHHHHHHHHHCCEEEEEEEEEECCCCHHH
LKIAERELSSKFDIIRASTENDINIDVIKKEIMNKIDL
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRVEANPFRKIPTILYADELLDKAHNRAEKVAGELRKTTRGESLYKSRIIEEQKIRAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAVISDYLSTVVKKTPSVDNLDPFYREILEILIDTDDFKKSLGALNWASDFSKKLGSMYG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRVHKAGSARHTSIIRKQFNGRISSVVKQIYPNLACIAVAREKLKNLPTVKDMPTVVIAG
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEC
YPNVGKSTLLRKLTNAEPEINAYPFTTKGLNVGYSDYGIQFVDTPGVLDRPIYERNDIEL
CCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
HAVVALNYLADLIVFVMDPTEYCGYTIEEQINLTNEIEKTFKVPIIIIINKIDIEGYEEN
HHHHHHHHHHHHHHHHCCCHHHCCEEHHHHCCHHHHHHHHHCCEEEEEEEEEECCCCHHH
LKIAERELSSKFDIIRASTENDINIDVIKKEIMNKIDL
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]