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The map label for this gene is rpiA

Identifier: 150401166

GI number: 150401166

Start: 755572

End: 756276

Strand: Reverse

Name: rpiA

Synonym: Maeo_0737

Alternate gene names: 150401166

Gene position: 756276-755572 (Counterclockwise)

Preceding gene: 150401167

Following gene: 150401165

Centisome position: 48.19

GC content: 33.76

Gene sequence:

>705_bases
ATGGCAAGAAAAAAAGCAGTTAAAGTAGAAGCTGACCCAAGATTAAATGCAGTAAATGAGGCCCTTAAATTTATAAAAGA
TGGAATGATTGTAGGATTGGGCTCAGGGACTACGGCAAATTTATTTATCGCGGAATTGGGCAAAAAAATATCGGAAGAGG
GTTTAAATGTATTTGGAGTTCCAACATCATTCGAATCTCGAATGATGGCTATTCAGTATGGCATCCCATTGGTATCTCTT
GACGAATATGGAGAGTTAGATATTGCGGTGGATGGTGCTGATGAAGTGAATAAAGAGACATTAAATGTTATAAAAGGTGG
CGGTGGTTGCCATACTCAAGAAAAAATAATTGATTATTGTGCAAAAGAGCTCATAATTATTGTGGATGAAAGTAAGCTTG
TGGATTCATTGGGGGAAAATACACCAGTTCCTCTTGAAGTTCTTCCATTTGCATATTCTTCCGTATTAAATGAATTATTG
AAAATGAATTCAGCACCTTCAATTAGGATGGCAGATAAAAAAATGGGCCCAGTGATTACAGATAATGGAAATATGATTAT
TGATGTATTTATTGATTTAAATAATCCCGAAGAAGTTGAAAAACAATTAAACAATATTCCAGGGGTTGTCGAAAATGGTA
TATTTACAAAAGTTGATAAAGTGATAGTAGGAAAATCTGATAAGGCAGAAATATTAAAAAAATAA

Upstream 100 bases:

>100_bases
CAAACTTTTCGAATACGATATATTTATGGTGTAATCTTTATATATTATTTTAACAACTATTTTGTATAAAACAACATAGA
TATAAAAAATCGGTGAAAAT

Downstream 100 bases:

>100_bases
ATATCATTAATCTTCGGTCTTTTTCATAAATATACTCTACAATTAAGCCAAAATAGCCTACTATATTACTAAAAAACATA
AAACCACATATAATTAGGAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MARKKAVKVEADPRLNAVNEALKFIKDGMIVGLGSGTTANLFIAELGKKISEEGLNVFGVPTSFESRMMAIQYGIPLVSL
DEYGELDIAVDGADEVNKETLNVIKGGGGCHTQEKIIDYCAKELIIIVDESKLVDSLGENTPVPLEVLPFAYSSVLNELL
KMNSAPSIRMADKKMGPVITDNGNMIIDVFIDLNNPEEVEKQLNNIPGVVENGIFTKVDKVIVGKSDKAEILKK

Sequences:

>Translated_234_residues
MARKKAVKVEADPRLNAVNEALKFIKDGMIVGLGSGTTANLFIAELGKKISEEGLNVFGVPTSFESRMMAIQYGIPLVSL
DEYGELDIAVDGADEVNKETLNVIKGGGGCHTQEKIIDYCAKELIIIVDESKLVDSLGENTPVPLEVLPFAYSSVLNELL
KMNSAPSIRMADKKMGPVITDNGNMIIDVFIDLNNPEEVEKQLNNIPGVVENGIFTKVDKVIVGKSDKAEILKK
>Mature_233_residues
ARKKAVKVEADPRLNAVNEALKFIKDGMIVGLGSGTTANLFIAELGKKISEEGLNVFGVPTSFESRMMAIQYGIPLVSLD
EYGELDIAVDGADEVNKETLNVIKGGGGCHTQEKIIDYCAKELIIIVDESKLVDSLGENTPVPLEVLPFAYSSVLNELLK
MNSAPSIRMADKKMGPVITDNGNMIIDVFIDLNNPEEVEKQLNNIPGVVENGIFTKVDKVIVGKSDKAEILKK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=208, Percent_Identity=40.3846153846154, Blast_Score=154, Evalue=5e-38,
Organism=Escherichia coli, GI1789280, Length=218, Percent_Identity=39.9082568807339, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17551758, Length=213, Percent_Identity=38.9671361502347, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=37.7777777777778, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281364072, Length=198, Percent_Identity=37.8787878787879, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_META3 (A6UUZ8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324932.1
- ProteinModelPortal:   A6UUZ8
- SMR:   A6UUZ8
- STRING:   A6UUZ8
- GeneID:   5327653
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0737
- eggNOG:   arNOG07879
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- BioCyc:   MAEO419665:MAEO_0737-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25365; Mature: 25234

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKKAVKVEADPRLNAVNEALKFIKDGMIVGLGSGTTANLFIAELGKKISEEGLNVFGV
CCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEC
PTSFESRMMAIQYGIPLVSLDEYGELDIAVDGADEVNKETLNVIKGGGGCHTQEKIIDYC
CCCHHHHEEEEEECCCEEEECCCCCEEEEECCCHHHCHHHHHHEECCCCCCHHHHHHHHH
AKELIIIVDESKLVDSLGENTPVPLEVLPFAYSSVLNELLKMNSAPSIRMADKKMGPVIT
HHHEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEE
DNGNMIIDVFIDLNNPEEVEKQLNNIPGVVENGIFTKVDKVIVGKSDKAEILKK
CCCCEEEEEEEECCCHHHHHHHHHCCCCHHHCCCHHHHHHEEECCCCHHHHHCC
>Mature Secondary Structure 
ARKKAVKVEADPRLNAVNEALKFIKDGMIVGLGSGTTANLFIAELGKKISEEGLNVFGV
CCCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEC
PTSFESRMMAIQYGIPLVSLDEYGELDIAVDGADEVNKETLNVIKGGGGCHTQEKIIDYC
CCCHHHHEEEEEECCCEEEECCCCCEEEEECCCHHHCHHHHHHEECCCCCCHHHHHHHHH
AKELIIIVDESKLVDSLGENTPVPLEVLPFAYSSVLNELLKMNSAPSIRMADKKMGPVIT
HHHEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEE
DNGNMIIDVFIDLNNPEEVEKQLNNIPGVVENGIFTKVDKVIVGKSDKAEILKK
CCCCEEEEEEEECCCHHHHHHHHHCCCCHHHCCCHHHHHHEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA