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The map label for this gene is mtaD [H]

Identifier: 150401084

GI number: 150401084

Start: 673615

End: 674886

Strand: Direct

Name: mtaD [H]

Synonym: Maeo_0654

Alternate gene names: 150401084

Gene position: 673615-674886 (Clockwise)

Preceding gene: 150401083

Following gene: 150401085

Centisome position: 42.92

GC content: 28.46

Gene sequence:

>1272_bases
ATGACAATATTAATAACAAATCTATCCTATTCAATAGATAATAATTTAAATGTATATAAAGATGTAGATATTTTAATAGA
TAATAACAATATAAAAATCGGAAAATTTTTAATGGAAAAAGAAAATATAAACCAAAAAGATTTAAAAATAATAGATGGAA
AAAATAAATGTGCCATGCCTGGATTGACAAATACTCACACCCACATACCAATGACATTATTAAGGGGCATCTCCGACGAT
ATGATTTTACAGGATTGGCTAAAAGAAAAAATATGGGTAAATGAGGCCAAACTCACAAAAGAAGCCGTTTATTATGGTTC
ATTGTTGGGCTGTCTTGAAATGTTAAGATTTGGAATTACTTCATTTAATGATATGTATTTTTTCAGTGAAGAAATATTAA
AAGCCACAAAAGAAATTGGATTAAAGGGAACAATTTGCTATCCAATAATTGATTTTGGAACTCCTGAACATGACAATTTA
GATAAATTATTAAATGGTGCGGAGAACTTTATAAAAAAATATAAAGACGAAAAAACCGTTAAACCTGCAATAGCTCCACA
TGCTCCATATACATGTTCAGAAAACACATATATAAAATGTAAAGAAATAGCAAATAAATATAATACGATTTTACACACCC
ACATATCAGAAACTAGATATGAAGTGGTGGAAATGGAAAATAATAAAAATATAAGGCCTGTGGATTATTTAAATAACCTA
AATATATTGGATAAAAATACAATTGTAGCACATTGTGTATGGATTACAAAAGACGAAGCAAAAACATTGGCAAAAACAGA
AACAAAAATATCCCACTGCTCAACAAGTAATATGAAGCTGGCAAGTGGTGGAGTTATGCCATTGGTGGAGCTCCTTCAAC
ACGGCGCAAATATATCACTTGGAACCGATGGTGTAGCAAGTAATAATAATATGGACATATTGGAACAAATGAAAATAACT
TCATTACTACATAAAGCCCATAGATGGGACCCAACAGTAGCCGACATAGATACAGTTTTAAAAATGGGAATTAATAGCCA
ATCTATTGGATTTGAAAATAATGATATTATATTAATTGATTTGGGAGCTCCACATATGCGACCAATACATAACATAAAAT
CAAATATAGTTTATTCTGCAAATGGAAATGATGTTGATACAGTAATTGTTAATGGAAAAATATTGATGGAAAATAAAAAA
TTCATATTTGAAGATGCAGTTATAAATAATATATATAATAAAGTAAATAAGATAGTAGAAAAATTTATTTAA

Upstream 100 bases:

>100_bases
ACTAATATCACCTAAAAATAAAAAAATCGGTGATATTATCTGCTAAAAATCACAGATTTTTAGACTAATATCACCTAAAA
ATAAAAAAATCGGTGATATT

Downstream 100 bases:

>100_bases
TAGGTATTTGGGTGAATTATGAAAATTGATATGCATGTTCATACTATAAATTCAAGATGTTCAATAAATCCAATAAAATT
ATTAAAAAAAATCTGTAATT

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTILITNLSYSIDNNLNVYKDVDILIDNNNIKIGKFLMEKENINQKDLKIIDGKNKCAMPGLTNTHTHIPMTLLRGISDD
MILQDWLKEKIWVNEAKLTKEAVYYGSLLGCLEMLRFGITSFNDMYFFSEEILKATKEIGLKGTICYPIIDFGTPEHDNL
DKLLNGAENFIKKYKDEKTVKPAIAPHAPYTCSENTYIKCKEIANKYNTILHTHISETRYEVVEMENNKNIRPVDYLNNL
NILDKNTIVAHCVWITKDEAKTLAKTETKISHCSTSNMKLASGGVMPLVELLQHGANISLGTDGVASNNNMDILEQMKIT
SLLHKAHRWDPTVADIDTVLKMGINSQSIGFENNDIILIDLGAPHMRPIHNIKSNIVYSANGNDVDTVIVNGKILMENKK
FIFEDAVINNIYNKVNKIVEKFI

Sequences:

>Translated_423_residues
MTILITNLSYSIDNNLNVYKDVDILIDNNNIKIGKFLMEKENINQKDLKIIDGKNKCAMPGLTNTHTHIPMTLLRGISDD
MILQDWLKEKIWVNEAKLTKEAVYYGSLLGCLEMLRFGITSFNDMYFFSEEILKATKEIGLKGTICYPIIDFGTPEHDNL
DKLLNGAENFIKKYKDEKTVKPAIAPHAPYTCSENTYIKCKEIANKYNTILHTHISETRYEVVEMENNKNIRPVDYLNNL
NILDKNTIVAHCVWITKDEAKTLAKTETKISHCSTSNMKLASGGVMPLVELLQHGANISLGTDGVASNNNMDILEQMKIT
SLLHKAHRWDPTVADIDTVLKMGINSQSIGFENNDIILIDLGAPHMRPIHNIKSNIVYSANGNDVDTVIVNGKILMENKK
FIFEDAVINNIYNKVNKIVEKFI
>Mature_422_residues
TILITNLSYSIDNNLNVYKDVDILIDNNNIKIGKFLMEKENINQKDLKIIDGKNKCAMPGLTNTHTHIPMTLLRGISDDM
ILQDWLKEKIWVNEAKLTKEAVYYGSLLGCLEMLRFGITSFNDMYFFSEEILKATKEIGLKGTICYPIIDFGTPEHDNLD
KLLNGAENFIKKYKDEKTVKPAIAPHAPYTCSENTYIKCKEIANKYNTILHTHISETRYEVVEMENNKNIRPVDYLNNLN
ILDKNTIVAHCVWITKDEAKTLAKTETKISHCSTSNMKLASGGVMPLVELLQHGANISLGTDGVASNNNMDILEQMKITS
LLHKAHRWDPTVADIDTVLKMGINSQSIGFENNDIILIDLGAPHMRPIHNIKSNIVYSANGNDVDTVIVNGKILMENKKF
IFEDAVINNIYNKVNKIVEKFI

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=321, Percent_Identity=26.1682242990654, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI87082177, Length=434, Percent_Identity=25.1152073732719, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789249, Length=302, Percent_Identity=24.5033112582781, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319963, Length=304, Percent_Identity=25.6578947368421, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643849, Length=272, Percent_Identity=27.5735294117647, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47867; Mature: 47736

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILITNLSYSIDNNLNVYKDVDILIDNNNIKIGKFLMEKENINQKDLKIIDGKNKCAMP
CEEEEEEEEEEECCCCEEEEEEEEEEECCCEEEHHEEHHHCCCCCCCEEEECCCCCCCCC
GLTNTHTHIPMTLLRGISDDMILQDWLKEKIWVNEAKLTKEAVYYGSLLGCLEMLRFGIT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SFNDMYFFSEEILKATKEIGLKGTICYPIIDFGTPEHDNLDKLLNGAENFIKKYKDEKTV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
KPAIAPHAPYTCSENTYIKCKEIANKYNTILHTHISETRYEVVEMENNKNIRPVDYLNNL
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHCCC
NILDKNTIVAHCVWITKDEAKTLAKTETKISHCSTSNMKLASGGVMPLVELLQHGANISL
CEECCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEE
GTDGVASNNNMDILEQMKITSLLHKAHRWDPTVADIDTVLKMGINSQSIGFENNDIILID
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LGAPHMRPIHNIKSNIVYSANGNDVDTVIVNGKILMENKKFIFEDAVINNIYNKVNKIVE
CCCCCCCHHHHHHCCEEEECCCCCEEEEEECCEEEEECCCEEHHHHHHHHHHHHHHHHHH
KFI
HHC
>Mature Secondary Structure 
TILITNLSYSIDNNLNVYKDVDILIDNNNIKIGKFLMEKENINQKDLKIIDGKNKCAMP
EEEEEEEEEEECCCCEEEEEEEEEEECCCEEEHHEEHHHCCCCCCCEEEECCCCCCCCC
GLTNTHTHIPMTLLRGISDDMILQDWLKEKIWVNEAKLTKEAVYYGSLLGCLEMLRFGIT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SFNDMYFFSEEILKATKEIGLKGTICYPIIDFGTPEHDNLDKLLNGAENFIKKYKDEKTV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
KPAIAPHAPYTCSENTYIKCKEIANKYNTILHTHISETRYEVVEMENNKNIRPVDYLNNL
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHCCC
NILDKNTIVAHCVWITKDEAKTLAKTETKISHCSTSNMKLASGGVMPLVELLQHGANISL
CEECCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEE
GTDGVASNNNMDILEQMKITSLLHKAHRWDPTVADIDTVLKMGINSQSIGFENNDIILID
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LGAPHMRPIHNIKSNIVYSANGNDVDTVIVNGKILMENKKFIFEDAVINNIYNKVNKIVE
CCCCCCCHHHHHHCCEEEECCCCCEEEEEECCEEEEECCCEEHHHHHHHHHHHHHHHHHH
KFI
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA