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The map label for this gene is pol [H]

Identifier: 150401083

GI number: 150401083

Start: 670989

End: 673424

Strand: Direct

Name: pol [H]

Synonym: Maeo_0653

Alternate gene names: 150401083

Gene position: 670989-673424 (Clockwise)

Preceding gene: 150401074

Following gene: 150401084

Centisome position: 42.75

GC content: 28.28

Gene sequence:

>2436_bases
ATGCTTTTAGATATTGATTATAATTCAAAAGAAAACCGTATTTATATATATACTACAAAGAAAATAATTAAAAAAGATTT
TAAACCATATTTATACATAGATGCCGATAAAAATACCATAAATAAGTTTATAGATGAGGAAGAACCACAACTTAAAGAAT
ATATAACGGCAATAGAAAGAGTAAAAAAAATTATTATAAATTTAAATGACATTGAAAATCCATATAAAAATAGGACAGTA
GAAAAGACTTTATCAAAAATAACAACAGACCACCCCAAAGACATTCCAAAATTACGAAAATTGCAAAAAATAAAGGCTAA
TCAGAGATTAGCCAATTTTCCCAATGGGAAAATAGGAACAACCTACGAACATGACATTCCATTTACAAAACGGTATTTAA
TTGATAATAATAAAAATATTGATTTATTAAATTATAATAATATACCAGATTTAAAAGCCGTATCTTTTGATATGGAGGTG
CATTTTAAAGATAGGGAGCCAGAACCTGAAAAAGATGCCATATTAATGACAAGTTTTTACTCACACGATAAAAAAATAAA
TAAAAAAATAAAAAAAGTAATTACCTACAAACCATTTGAGCATGAAAGCGTTGAAATTGTAAAGGACGAAAAGGAATTAA
TTAAAAAAACCATGGAGCTCCTAAAACAATATAATATAATATACACCTACAACGGAGATAATTTTGATTTCCCATATTTA
AAAAGACGGGCAGAACATTTAAAAATACCATTAAATTTTGGAGAAAATCATAAATTAAAATTATCAAAAGGGGGCATGAA
TTTAAAAAGTGCAATTTCTGGAATTGTGCATATTGACCTTTACCCCATAGCAAGAAGAACCTTAAATTTAACCAAATATA
AATTAGAAGATGTTTCAAAAGAATTATTTAACATAGAAAAATTAGAGGTTGGACATCATAATATAGTGCCACTATGGAAC
AATAATAACCCCAAATTAGTAGAATACTCACTCCAAGATGCAGAATATACATATAAAATAGGGGAATATTTTTTGCCATT
AGAAATTATGTTTTCAAATATTGTTGGCCAATGTTTATTTGATATAAGTAGAATGAGTAGTAGCAATATGGTAGAATATC
TACTTTTAAAGCATTCATTCAATAAAAATTATTTGGCACCAAATAGACCTTATGGCAATGAATACCAAAACAGATTAAAA
GAAGGTTATGAGGGAGGATATGTAAAAGAGCCCATAAAAGGCATGCATGATAACATAGTTAGCATGGATTTCAGAGCTCT
ATATCCATCTATAATAATAAGCTATAATATAAGCCCCGATACAATAAACTGCCCTTGTTGTGGTGATACCAACGATAAAA
TATTGGGTTATTGGTTCTGTAAAAAAAAGATAGGTATTATACCTGAAATTCTAAAAGATTTAATTGAAAGAAGGAAAAAT
ATTAAAGATGTTTTAAAAAATAAAAATACAACAGAGAATAATAAAGACGATAATAACAAAAACAACAACGAAAATTATAA
ATTATTAAATTATGAACAACAATCAATAAAAATTTTAGCAAATTCATTCTATGGTTATATGGCTTATCCGCGGGCAAGAT
GGTATTCCAAAGAATGTGCCGAAGTAATTACTCATTTAGGTAGGGCATATATACGAAAAACAATAGAGGAAGCGGAAAAT
AACGGATTTAATGTAATATATGCAGATACTGACGGATTATATGCGATATTAGACGAAAATAAAAATAAAAATACAAATAA
AGAAAATATATTAAATAAAACCATCAAATTTTTAAATGAAATAAACAGGGAGCTCCCCGAAAAGATGGAGCTCGAATTTG
AAGGATACTACAAAAGAGGTATATTCATAACTAAAAAAAGATATGCCTTAATTGATGAAAACAATAAAATTATAGTAAAA
GGTTTGGAATTTGTAAGAAGGGATTGGTCAAATATAGCCAAAAAAACCCAAAAAAAAGTATTAAATACACTTTTAAAAGA
AGGAGATGTAGAAACTGCAAAACAGATTATTAAAGATACAATAAATGATTTAAAAAATCTACCCCAATCGAAGATTGGTG
AATCCCCGGGGGGAGATAAAAAAATAAACCCCAAAGATTTAATAATATATAAACAACTAACAAAAGATATTAGCGAATAT
TCCACAGCCACACCCCACATAGCAGTTGCCAAAAAAATGAGAGACAGAGGAGATAGGTTAAAAATCGGTGATGTAATTGG
TTTCGTAATTGTAAATGGGAGCTCCCCAATAAGTGAAAGGGCTACCATCCCAGAACAAGCCACCAACTACGATGCAAATT
ATTATATTGATAATCAGGTGCTACCCCCAGTATTAAGAATTATGGAAGCTATTGGAATTACCAAAGATGAGCTAAAAAAC
AATAATAAACAAATTACACTTGATAATTTCTTTTAA

Upstream 100 bases:

>100_bases
AATGGATATACAATCACAATATTCATTATATATTAATCATAATCATTTTAATTATTAACCATAAATAATTTACCTAATTT
TTATATATTGTGGTGTTATC

Downstream 100 bases:

>100_bases
ATAATTATATTATAAAATGTCCTGTATTAAAAAATAAATATAAAATTATCGTGATATTATCCGATGAATTTCACTTCGTG
AAAATTCATTACTAATATCA

Product: DNA polymerase Pol2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MLLDIDYNSKENRIYIYTTKKIIKKDFKPYLYIDADKNTINKFIDEEEPQLKEYITAIERVKKIIINLNDIENPYKNRTV
EKTLSKITTDHPKDIPKLRKLQKIKANQRLANFPNGKIGTTYEHDIPFTKRYLIDNNKNIDLLNYNNIPDLKAVSFDMEV
HFKDREPEPEKDAILMTSFYSHDKKINKKIKKVITYKPFEHESVEIVKDEKELIKKTMELLKQYNIIYTYNGDNFDFPYL
KRRAEHLKIPLNFGENHKLKLSKGGMNLKSAISGIVHIDLYPIARRTLNLTKYKLEDVSKELFNIEKLEVGHHNIVPLWN
NNNPKLVEYSLQDAEYTYKIGEYFLPLEIMFSNIVGQCLFDISRMSSSNMVEYLLLKHSFNKNYLAPNRPYGNEYQNRLK
EGYEGGYVKEPIKGMHDNIVSMDFRALYPSIIISYNISPDTINCPCCGDTNDKILGYWFCKKKIGIIPEILKDLIERRKN
IKDVLKNKNTTENNKDDNNKNNNENYKLLNYEQQSIKILANSFYGYMAYPRARWYSKECAEVITHLGRAYIRKTIEEAEN
NGFNVIYADTDGLYAILDENKNKNTNKENILNKTIKFLNEINRELPEKMELEFEGYYKRGIFITKKRYALIDENNKIIVK
GLEFVRRDWSNIAKKTQKKVLNTLLKEGDVETAKQIIKDTINDLKNLPQSKIGESPGGDKKINPKDLIIYKQLTKDISEY
STATPHIAVAKKMRDRGDRLKIGDVIGFVIVNGSSPISERATIPEQATNYDANYYIDNQVLPPVLRIMEAIGITKDELKN
NNKQITLDNFF

Sequences:

>Translated_811_residues
MLLDIDYNSKENRIYIYTTKKIIKKDFKPYLYIDADKNTINKFIDEEEPQLKEYITAIERVKKIIINLNDIENPYKNRTV
EKTLSKITTDHPKDIPKLRKLQKIKANQRLANFPNGKIGTTYEHDIPFTKRYLIDNNKNIDLLNYNNIPDLKAVSFDMEV
HFKDREPEPEKDAILMTSFYSHDKKINKKIKKVITYKPFEHESVEIVKDEKELIKKTMELLKQYNIIYTYNGDNFDFPYL
KRRAEHLKIPLNFGENHKLKLSKGGMNLKSAISGIVHIDLYPIARRTLNLTKYKLEDVSKELFNIEKLEVGHHNIVPLWN
NNNPKLVEYSLQDAEYTYKIGEYFLPLEIMFSNIVGQCLFDISRMSSSNMVEYLLLKHSFNKNYLAPNRPYGNEYQNRLK
EGYEGGYVKEPIKGMHDNIVSMDFRALYPSIIISYNISPDTINCPCCGDTNDKILGYWFCKKKIGIIPEILKDLIERRKN
IKDVLKNKNTTENNKDDNNKNNNENYKLLNYEQQSIKILANSFYGYMAYPRARWYSKECAEVITHLGRAYIRKTIEEAEN
NGFNVIYADTDGLYAILDENKNKNTNKENILNKTIKFLNEINRELPEKMELEFEGYYKRGIFITKKRYALIDENNKIIVK
GLEFVRRDWSNIAKKTQKKVLNTLLKEGDVETAKQIIKDTINDLKNLPQSKIGESPGGDKKINPKDLIIYKQLTKDISEY
STATPHIAVAKKMRDRGDRLKIGDVIGFVIVNGSSPISERATIPEQATNYDANYYIDNQVLPPVLRIMEAIGITKDELKN
NNKQITLDNFF
>Mature_811_residues
MLLDIDYNSKENRIYIYTTKKIIKKDFKPYLYIDADKNTINKFIDEEEPQLKEYITAIERVKKIIINLNDIENPYKNRTV
EKTLSKITTDHPKDIPKLRKLQKIKANQRLANFPNGKIGTTYEHDIPFTKRYLIDNNKNIDLLNYNNIPDLKAVSFDMEV
HFKDREPEPEKDAILMTSFYSHDKKINKKIKKVITYKPFEHESVEIVKDEKELIKKTMELLKQYNIIYTYNGDNFDFPYL
KRRAEHLKIPLNFGENHKLKLSKGGMNLKSAISGIVHIDLYPIARRTLNLTKYKLEDVSKELFNIEKLEVGHHNIVPLWN
NNNPKLVEYSLQDAEYTYKIGEYFLPLEIMFSNIVGQCLFDISRMSSSNMVEYLLLKHSFNKNYLAPNRPYGNEYQNRLK
EGYEGGYVKEPIKGMHDNIVSMDFRALYPSIIISYNISPDTINCPCCGDTNDKILGYWFCKKKIGIIPEILKDLIERRKN
IKDVLKNKNTTENNKDDNNKNNNENYKLLNYEQQSIKILANSFYGYMAYPRARWYSKECAEVITHLGRAYIRKTIEEAEN
NGFNVIYADTDGLYAILDENKNKNTNKENILNKTIKFLNEINRELPEKMELEFEGYYKRGIFITKKRYALIDENNKIIVK
GLEFVRRDWSNIAKKTQKKVLNTLLKEGDVETAKQIIKDTINDLKNLPQSKIGESPGGDKKINPKDLIIYKQLTKDISEY
STATPHIAVAKKMRDRGDRLKIGDVIGFVIVNGSSPISERATIPEQATNYDANYYIDNQVLPPVLRIMEAIGITKDELKN
NNKQITLDNFF

Specific function: Thought To Be Involved In DNA Repair And/Or Mutagenesis. [C]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=707, Percent_Identity=26.3083451202263, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI106507301, Length=649, Percent_Identity=26.9645608628659, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI153792012, Length=665, Percent_Identity=22.7067669172932, Blast_Score=124, Evalue=5e-28,
Organism=Escherichia coli, GI1786246, Length=632, Percent_Identity=23.8924050632911, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17559488, Length=720, Percent_Identity=26.9444444444444, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI32565317, Length=589, Percent_Identity=27.1646859083192, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI86563326, Length=495, Percent_Identity=23.030303030303, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17507143, Length=488, Percent_Identity=24.1803278688525, Blast_Score=81, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320101, Length=877, Percent_Identity=25.8836944127708, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324227, Length=758, Percent_Identity=25.197889182058, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6325090, Length=700, Percent_Identity=22.8571428571429, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648780, Length=625, Percent_Identity=26.88, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24664937, Length=727, Percent_Identity=27.6478679504814, Blast_Score=179, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24586371, Length=784, Percent_Identity=21.6836734693878, Blast_Score=115, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR004578
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 94743; Mature: 94743

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDIDYNSKENRIYIYTTKKIIKKDFKPYLYIDADKNTINKFIDEEEPQLKEYITAIER
CEEECCCCCCCCEEEEEECHHHHHHCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHH
VKKIIINLNDIENPYKNRTVEKTLSKITTDHPKDIPKLRKLQKIKANQRLANFPNGKIGT
HHHHHHCCHHCCCCHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TYEHDIPFTKRYLIDNNKNIDLLNYNNIPDLKAVSFDMEVHFKDREPEPEKDAILMTSFY
CEECCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEHHH
SHDKKINKKIKKVITYKPFEHESVEIVKDEKELIKKTMELLKQYNIIYTYNGDNFDFPYL
HHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
KRRAEHLKIPLNFGENHKLKLSKGGMNLKSAISGIVHIDLYPIARRTLNLTKYKLEDVSK
HHHHHHEEEEECCCCCCEEEEECCCCCHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHH
ELFNIEKLEVGHHNIVPLWNNNNPKLVEYSLQDAEYTYKIGEYFLPLEIMFSNIVGQCLF
HHHCCHHEECCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
DISRMSSSNMVEYLLLKHSFNKNYLAPNRPYGNEYQNRLKEGYEGGYVKEPIKGMHDNIV
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHH
SMDFRALYPSIIISYNISPDTINCPCCGDTNDKILGYWFCKKKIGIIPEILKDLIERRKN
HHHHHHHCCEEEEEEECCCCCEECCCCCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHH
IKDVLKNKNTTENNKDDNNKNNNENYKLLNYEQQSIKILANSFYGYMAYPRARWYSKECA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
EVITHLGRAYIRKTIEEAENNGFNVIYADTDGLYAILDENKNKNTNKENILNKTIKFLNE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
INRELPEKMELEFEGYYKRGIFITKKRYALIDENNKIIVKGLEFVRRDWSNIAKKTQKKV
HHHHCCHHHEEEECCEEECCEEEEECEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHH
LNTLLKEGDVETAKQIIKDTINDLKNLPQSKIGESPGGDKKINPKDLIIYKQLTKDISEY
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHEEEHHHHHHHHHHH
STATPHIAVAKKMRDRGDRLKIGDVIGFVIVNGSSPISERATIPEQATNYDANYYIDNQV
CCCCCHHHHHHHHHCCCCCEEECCEEEEEEECCCCCCHHCCCCCCHHCCCCCCEEECCCC
LPPVLRIMEAIGITKDELKNNNKQITLDNFF
CHHHHHHHHHHCCCHHHHCCCCCEEEECCCC
>Mature Secondary Structure
MLLDIDYNSKENRIYIYTTKKIIKKDFKPYLYIDADKNTINKFIDEEEPQLKEYITAIER
CEEECCCCCCCCEEEEEECHHHHHHCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHH
VKKIIINLNDIENPYKNRTVEKTLSKITTDHPKDIPKLRKLQKIKANQRLANFPNGKIGT
HHHHHHCCHHCCCCHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TYEHDIPFTKRYLIDNNKNIDLLNYNNIPDLKAVSFDMEVHFKDREPEPEKDAILMTSFY
CEECCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEHHH
SHDKKINKKIKKVITYKPFEHESVEIVKDEKELIKKTMELLKQYNIIYTYNGDNFDFPYL
HHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
KRRAEHLKIPLNFGENHKLKLSKGGMNLKSAISGIVHIDLYPIARRTLNLTKYKLEDVSK
HHHHHHEEEEECCCCCCEEEEECCCCCHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHH
ELFNIEKLEVGHHNIVPLWNNNNPKLVEYSLQDAEYTYKIGEYFLPLEIMFSNIVGQCLF
HHHCCHHEECCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
DISRMSSSNMVEYLLLKHSFNKNYLAPNRPYGNEYQNRLKEGYEGGYVKEPIKGMHDNIV
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHH
SMDFRALYPSIIISYNISPDTINCPCCGDTNDKILGYWFCKKKIGIIPEILKDLIERRKN
HHHHHHHCCEEEEEEECCCCCEECCCCCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHH
IKDVLKNKNTTENNKDDNNKNNNENYKLLNYEQQSIKILANSFYGYMAYPRARWYSKECA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
EVITHLGRAYIRKTIEEAENNGFNVIYADTDGLYAILDENKNKNTNKENILNKTIKFLNE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
INRELPEKMELEFEGYYKRGIFITKKRYALIDENNKIIVKGLEFVRRDWSNIAKKTQKKV
HHHHCCHHHEEEECCEEECCEEEEECEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHH
LNTLLKEGDVETAKQIIKDTINDLKNLPQSKIGESPGGDKKINPKDLIIYKQLTKDISEY
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHEEEHHHHHHHHHHH
STATPHIAVAKKMRDRGDRLKIGDVIGFVIVNGSSPISERATIPEQATNYDANYYIDNQV
CCCCCHHHHHHHHHCCCCCEEECCEEEEEEECCCCCCHHCCCCCCHHCCCCCCEEECCCC
LPPVLRIMEAIGITKDELKNNNKQITLDNFF
CHHHHHHHHHHCCCHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929013 [H]