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The map label for this gene is spcS [H]

Identifier: 150400984

GI number: 150400984

Start: 566804

End: 568237

Strand: Reverse

Name: spcS [H]

Synonym: Maeo_0553

Alternate gene names: 150400984

Gene position: 568237-566804 (Counterclockwise)

Preceding gene: 150400987

Following gene: 150400983

Centisome position: 36.2

GC content: 31.24

Gene sequence:

>1434_bases
ATGATTGATTTAAATATTAGTGGAATAATTCCAAAAAATATGGAAAATAGGGGAAAACTCGTATTAAATGATAATTTAAA
AAATATTGAAGATATTTTTAATCATAGAGTAATTCCCAAACAGGCAATGAGTGATGAAGAGATAGAACTTTTTTTAAAAT
TACTATCTTTAATGGATACAGATAAAGACCCAAAATCTATAAGAATAGGGGAGCGGGAGGCTAGAACCTCTTCAAATATC
CACAATAGATTAGTTTCTGGTTTTTGTCATGGGGTGGGAAGAAGTGGAAATTTAATCGATCCACAGCCAAAAGCACCTGG
TGCAAGTGTGATGTATTCATTAACCAATAGCATATTAACAAGTTTCTTAAAAAAATTGGGGCTAAATGTTTCAGCAATAG
CCACCCCCATAGCAACAGGCATGTCTATATCATTATGTTTAAGTGCATTAAGAAAAAAATATGGTTGTAATACTGTAATT
TATCCATACGCAGCACATAAAAGCCCAATAAAAGCCGTATCTTTTTCAGGATTAAAAATGAGATTGGTTGAAACGGTTCT
ATCCGAAGACGGTGAATCTGTCTTCGTTCCTGTTGAAGATATCGAAAATGCCATAAAAAAAGAAATAAATAAAAATGATA
AATATGGGGACAGCAATATTTATACTACTAAATATAATATAAATAATAAAAAAGAAATACCTTGTGTATTAAGCACTTTA
ACCTTCTTCCCCCCTCGGAAAAGTGATGATATCGTAGAAATAGCAAAGATTTGTGAAGAATATAATATTCCCCATATTAT
TAATGGTGCCTATGCCATTCAAAATCAATATTATATTGATAGATTAAAAAAGGCATTTAAATATCGGGTAGATGCCGTTA
TAAGTTCTTCCGATAAAAATTTATTAACTCCGATTGGAGGGGGAATAATTTATTCAAAAGATAAAGAATTCATAAATGAA
ATATCAAAAACATATCCTGGACGAGCATGTGCAACCCCGATAGTGAATACGCTAGTTTCATTGTTATCAATTGGACTAAA
TAACTATAAAGAACTTATGAAACAGCAGAAAGAAAGTAGAAAATTATTGCATGACCTACTAGTCGAACTTGCCAATAATA
CCAATAACAAAGTTTTAAATATTGATAGTCCATTATCTATATGCATTACTACGAATTCAGACCCTGTTGAAATAGCAGGT
AAATTATATAATTTAAGAATCACCGGTCCGAGGGGAGTTAGGAGCTCCGATAAATTTGGAAATTGTTATTTGGGAAATTT
CCCATACGATTATGTTGTAATGAACGCGGCTATTGGCATTAAAAATAAAGACATAATTAATGCAGTTGATAAATTAAAAT
ATAGTATGGCCAAAAATAAGAATATAATGTCGGGTGAAAAGAATGGCAATAACTATTGCAATAGCATCAGGTAA

Upstream 100 bases:

>100_bases
TAAATAATAAATAATAAATAATAAAATAATATTACACAATATTTAATAATGTATATATTCATTAAATATAAAATATATGA
TATAATATGATGATGTTAAT

Downstream 100 bases:

>100_bases
AGGAGGAACTGGTAAGACCACCACATCGGCAAATTTATCTGTTGCATTAACAAAATTTGGAAAAGATGTAATTGTACTTG
ATTTGGATATTGCTATGGCA

Product: soluble liver antigen/liver pancreas antigen

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MIDLNISGIIPKNMENRGKLVLNDNLKNIEDIFNHRVIPKQAMSDEEIELFLKLLSLMDTDKDPKSIRIGEREARTSSNI
HNRLVSGFCHGVGRSGNLIDPQPKAPGASVMYSLTNSILTSFLKKLGLNVSAIATPIATGMSISLCLSALRKKYGCNTVI
YPYAAHKSPIKAVSFSGLKMRLVETVLSEDGESVFVPVEDIENAIKKEINKNDKYGDSNIYTTKYNINNKKEIPCVLSTL
TFFPPRKSDDIVEIAKICEEYNIPHIINGAYAIQNQYYIDRLKKAFKYRVDAVISSSDKNLLTPIGGGIIYSKDKEFINE
ISKTYPGRACATPIVNTLVSLLSIGLNNYKELMKQQKESRKLLHDLLVELANNTNNKVLNIDSPLSICITTNSDPVEIAG
KLYNLRITGPRGVRSSDKFGNCYLGNFPYDYVVMNAAIGIKNKDIINAVDKLKYSMAKNKNIMSGEKNGNNYCNSIR

Sequences:

>Translated_477_residues
MIDLNISGIIPKNMENRGKLVLNDNLKNIEDIFNHRVIPKQAMSDEEIELFLKLLSLMDTDKDPKSIRIGEREARTSSNI
HNRLVSGFCHGVGRSGNLIDPQPKAPGASVMYSLTNSILTSFLKKLGLNVSAIATPIATGMSISLCLSALRKKYGCNTVI
YPYAAHKSPIKAVSFSGLKMRLVETVLSEDGESVFVPVEDIENAIKKEINKNDKYGDSNIYTTKYNINNKKEIPCVLSTL
TFFPPRKSDDIVEIAKICEEYNIPHIINGAYAIQNQYYIDRLKKAFKYRVDAVISSSDKNLLTPIGGGIIYSKDKEFINE
ISKTYPGRACATPIVNTLVSLLSIGLNNYKELMKQQKESRKLLHDLLVELANNTNNKVLNIDSPLSICITTNSDPVEIAG
KLYNLRITGPRGVRSSDKFGNCYLGNFPYDYVVMNAAIGIKNKDIINAVDKLKYSMAKNKNIMSGEKNGNNYCNSIR
>Mature_477_residues
MIDLNISGIIPKNMENRGKLVLNDNLKNIEDIFNHRVIPKQAMSDEEIELFLKLLSLMDTDKDPKSIRIGEREARTSSNI
HNRLVSGFCHGVGRSGNLIDPQPKAPGASVMYSLTNSILTSFLKKLGLNVSAIATPIATGMSISLCLSALRKKYGCNTVI
YPYAAHKSPIKAVSFSGLKMRLVETVLSEDGESVFVPVEDIENAIKKEINKNDKYGDSNIYTTKYNINNKKEIPCVLSTL
TFFPPRKSDDIVEIAKICEEYNIPHIINGAYAIQNQYYIDRLKKAFKYRVDAVISSSDKNLLTPIGGGIIYSKDKEFINE
ISKTYPGRACATPIVNTLVSLLSIGLNNYKELMKQQKESRKLLHDLLVELANNTNNKVLNIDSPLSICITTNSDPVEIAG
KLYNLRITGPRGVRSSDKFGNCYLGNFPYDYVVMNAAIGIKNKDIINAVDKLKYSMAKNKNIMSGEKNGNNYCNSIR

Specific function: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SepSecS family [H]

Homologues:

Organism=Homo sapiens, GI267844904, Length=453, Percent_Identity=31.1258278145695, Blast_Score=220, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI212646307, Length=461, Percent_Identity=29.5010845986985, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17559116, Length=461, Percent_Identity=29.5010845986985, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI221377925, Length=486, Percent_Identity=29.8353909465021, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR019872
- InterPro:   IPR008829 [H]

Pfam domain/function: PF05889 SLA_LP_auto_ag [H]

EC number: =2.9.1.2 [H]

Molecular weight: Translated: 53112; Mature: 53112

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLNISGIIPKNMENRGKLVLNDNLKNIEDIFNHRVIPKQAMSDEEIELFLKLLSLMDT
CEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCC
DKDPKSIRIGEREARTSSNIHNRLVSGFCHGVGRSGNLIDPQPKAPGASVMYSLTNSILT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SFLKKLGLNVSAIATPIATGMSISLCLSALRKKYGCNTVIYPYAAHKSPIKAVSFSGLKM
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCHHH
RLVETVLSEDGESVFVPVEDIENAIKKEINKNDKYGDSNIYTTKYNINNKKEIPCVLSTL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
TFFPPRKSDDIVEIAKICEEYNIPHIINGAYAIQNQYYIDRLKKAFKYRVDAVISSSDKN
HCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHEECCCCC
LLTPIGGGIIYSKDKEFINEISKTYPGRACATPIVNTLVSLLSIGLNNYKELMKQQKESR
EECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
KLLHDLLVELANNTNNKVLNIDSPLSICITTNSDPVEIAGKLYNLRITGPRGVRSSDKFG
HHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCC
NCYLGNFPYDYVVMNAAIGIKNKDIINAVDKLKYSMAKNKNIMSGEKNGNNYCNSIR
CEEECCCCHHHEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MIDLNISGIIPKNMENRGKLVLNDNLKNIEDIFNHRVIPKQAMSDEEIELFLKLLSLMDT
CEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCC
DKDPKSIRIGEREARTSSNIHNRLVSGFCHGVGRSGNLIDPQPKAPGASVMYSLTNSILT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SFLKKLGLNVSAIATPIATGMSISLCLSALRKKYGCNTVIYPYAAHKSPIKAVSFSGLKM
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCHHH
RLVETVLSEDGESVFVPVEDIENAIKKEINKNDKYGDSNIYTTKYNINNKKEIPCVLSTL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
TFFPPRKSDDIVEIAKICEEYNIPHIINGAYAIQNQYYIDRLKKAFKYRVDAVISSSDKN
HCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHEECCCCC
LLTPIGGGIIYSKDKEFINEISKTYPGRACATPIVNTLVSLLSIGLNNYKELMKQQKESR
EECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
KLLHDLLVELANNTNNKVLNIDSPLSICITTNSDPVEIAGKLYNLRITGPRGVRSSDKFG
HHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCC
NCYLGNFPYDYVVMNAAIGIKNKDIINAVDKLKYSMAKNKNIMSGEKNGNNYCNSIR
CEEECCCCHHHEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA