Click here to switch to the map view.

The map label for this gene is nadA [H]

Identifier: 150400977

GI number: 150400977

Start: 561154

End: 562071

Strand: Reverse

Name: nadA [H]

Synonym: Maeo_0546

Alternate gene names: 150400977

Gene position: 562071-561154 (Counterclockwise)

Preceding gene: 150400978

Following gene: 150400974

Centisome position: 35.81

GC content: 31.92

Gene sequence:

>918_bases
ATGGATATAATAGAAAGAATAAACACAATCAAAAAAGAAAAAAATGCTATAATATTAGCACATAATTATCAGCCAGAAGA
AATTCAAAATATTGCTGATTTTGTGGGGGATTCATTGGAATTATGTATTATTGCCAAAGAAACCACTGCGGATATTATTG
TATTTTGTGGCGTAGATTTTATGGCTGAAACTGCAAAAATATTAAATAAGGATAAAAAAGTTTTAATTCCTGAGATTAAG
GATGTAGAATGTCCAATGGCACACCAATTACCTCCAAAAATCATATTGGATGCAAAAAAAGAACACCCTAATGCAAAAGT
TGTAATTTATGTAAATACCCTTGCTTCTGCAAAGGCAATAGCTGACTCAACTTGCACATCTGCAAATGCGGATAAAGTAA
TAAATTCATTTGAAGAGGATAAAATATTATTTGGACCAGACAATAATTTAGGATATTTTGTAAGTAAAAGAACAGATAAA
GAAATAATCTGCATCCCAAAAGATGGAGGTTGTTATGTTCATCAGAAATTTAAAAAAGAAGATGTTATAGCCGCGAAAAA
ACAATATCCTAATGCTGTATGCATAGCACACCCAGAATGTGCCCCTGAGGTTCAAGATTTGGCCGATGCCGTATTGAGCA
CAGGCGGAATGGTTAAATTTGTACTGGAAACTCCAGCAGAAGAAATAATAATAGGAACAGAATGCGATATGATAGTTAGG
TTAAACCATGAATTAAAAAAGGCAGGTAAAACAAAAAAATTGATACCGCTTAGAAAAGATGCTATTTGTGACCCGATGAA
ACAAATGACACTTGAAAAAGTAGAAAAATGTTTAATCAATGAAGAATATGAAATAACCCTTGATGAAGAGGTCATTGAAC
AGGCAAAAAAATCAATTGAAAGAATGTTGAATATTTAA

Upstream 100 bases:

>100_bases
ATTGAGTGCTTAAAAATAATAAATAAAATTAATAAATAATAAAAAATAACTGAAATAATTATATTACGATTAATATTTAA
ACAATTTAGTGAGGAATAAT

Downstream 100 bases:

>100_bases
TATATTTATATTTTTATTATTTTTATTATTATTTTTATCTTTCATCATCTAACGATTGACTTGATGAATGAGCGATTTTA
CTCATATAAGTTTGATAAAC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDIIERINTIKKEKNAIILAHNYQPEEIQNIADFVGDSLELCIIAKETTADIIVFCGVDFMAETAKILNKDKKVLIPEIK
DVECPMAHQLPPKIILDAKKEHPNAKVVIYVNTLASAKAIADSTCTSANADKVINSFEEDKILFGPDNNLGYFVSKRTDK
EIICIPKDGGCYVHQKFKKEDVIAAKKQYPNAVCIAHPECAPEVQDLADAVLSTGGMVKFVLETPAEEIIIGTECDMIVR
LNHELKKAGKTKKLIPLRKDAICDPMKQMTLEKVEKCLINEEYEITLDEEVIEQAKKSIERMLNI

Sequences:

>Translated_305_residues
MDIIERINTIKKEKNAIILAHNYQPEEIQNIADFVGDSLELCIIAKETTADIIVFCGVDFMAETAKILNKDKKVLIPEIK
DVECPMAHQLPPKIILDAKKEHPNAKVVIYVNTLASAKAIADSTCTSANADKVINSFEEDKILFGPDNNLGYFVSKRTDK
EIICIPKDGGCYVHQKFKKEDVIAAKKQYPNAVCIAHPECAPEVQDLADAVLSTGGMVKFVLETPAEEIIIGTECDMIVR
LNHELKKAGKTKKLIPLRKDAICDPMKQMTLEKVEKCLINEEYEITLDEEVIEQAKKSIERMLNI
>Mature_305_residues
MDIIERINTIKKEKNAIILAHNYQPEEIQNIADFVGDSLELCIIAKETTADIIVFCGVDFMAETAKILNKDKKVLIPEIK
DVECPMAHQLPPKIILDAKKEHPNAKVVIYVNTLASAKAIADSTCTSANADKVINSFEEDKILFGPDNNLGYFVSKRTDK
EIICIPKDGGCYVHQKFKKEDVIAAKKQYPNAVCIAHPECAPEVQDLADAVLSTGGMVKFVLETPAEEIIIGTECDMIVR
LNHELKKAGKTKKLIPLRKDAICDPMKQMTLEKVEKCLINEEYEITLDEEVIEQAKKSIERMLNI

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=314, Percent_Identity=32.484076433121, Blast_Score=163, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34111; Mature: 34111

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIERINTIKKEKNAIILAHNYQPEEIQNIADFVGDSLELCIIAKETTADIIVFCGVDF
CCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCHH
MAETAKILNKDKKVLIPEIKDVECPMAHQLPPKIILDAKKEHPNAKVVIYVNTLASAKAI
HHHHHHHHCCCCEEECCCCCCCCCCHHHCCCCCEEEECCCCCCCCEEEEEEECCHHHHHH
ADSTCTSANADKVINSFEEDKILFGPDNNLGYFVSKRTDKEIICIPKDGGCYVHQKFKKE
HCCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEEECCCCCEEEEEECCCCEEEHHHHCHH
DVIAAKKQYPNAVCIAHPECAPEVQDLADAVLSTGGMVKFVLETPAEEIIIGTECDMIVR
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCEEEE
LNHELKKAGKTKKLIPLRKDAICDPMKQMTLEKVEKCLINEEYEITLDEEVIEQAKKSIE
ECHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
RMLNI
HHHCC
>Mature Secondary Structure
MDIIERINTIKKEKNAIILAHNYQPEEIQNIADFVGDSLELCIIAKETTADIIVFCGVDF
CCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCHH
MAETAKILNKDKKVLIPEIKDVECPMAHQLPPKIILDAKKEHPNAKVVIYVNTLASAKAI
HHHHHHHHCCCCEEECCCCCCCCCCHHHCCCCCEEEECCCCCCCCEEEEEEECCHHHHHH
ADSTCTSANADKVINSFEEDKILFGPDNNLGYFVSKRTDKEIICIPKDGGCYVHQKFKKE
HCCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEEECCCCCEEEEEECCCCEEEHHHHCHH
DVIAAKKQYPNAVCIAHPECAPEVQDLADAVLSTGGMVKFVLETPAEEIIIGTECDMIVR
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCEEEE
LNHELKKAGKTKKLIPLRKDAICDPMKQMTLEKVEKCLINEEYEITLDEEVIEQAKKSIE
ECHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
RMLNI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]