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The map label for this gene is pheA [H]

Identifier: 150400931

GI number: 150400931

Start: 522038

End: 522874

Strand: Direct

Name: pheA [H]

Synonym: Maeo_0499

Alternate gene names: 150400931

Gene position: 522038-522874 (Clockwise)

Preceding gene: 150400930

Following gene: 150400948

Centisome position: 33.26

GC content: 27.36

Gene sequence:

>837_bases
ATGATTTATTGCTTGGGACCAAAAGGAAGCTATACAGAAGAGGCAGCAGAAATATTTTCAAAAATAATAAAAGATAAAAA
TATTGAATATTGCAACTCGATATATGAAGTATTTGAACGAGTAGAACAGGGAAATAATAATTGTTATGGGGTAGTTCCTT
CTGAAAACTCCATAGAAGGTTCTGTATCTCTTACAATGGATTTACTTTTAGAATTTCCTGTAAAAATATTGGGGGAAGTA
GATATAAATATAAATCACTGTTTAATTGGATACAGTAAAGATAAAATTAAAAAAATATTGGCTCATCCACAGGCATTGGC
CCAATGTAGAAAATATATAAAAAAACACGATTGGGAAACAGAATCAGTTTTAAGCAATAGTATGGCGGTTAAAAAAGTAT
ATGATATGAAAAACGAAGAATTAGGGGCAATAGCATCAAAAAAAGCTGGAAAATTATATAATTTAAATATTCTTGATACA
AATATACAGGATTATCCAAACAACACCACACGATTTATATTAATTGGAAAGGACTGTGAAGATTCAAATGATATATCATT
TACTAATAACGACACTACAAAAAAATCTACAATAATAATTGAATTAATCGGGAATAAACCCGGAGCCCTATACAATATAT
TAAAAGAATTCAATAAAAAAAATATCAATTTAACGAGAATAGAATCCCGACCATCTAAAACAAAATTGGGTAGTTATATA
TTTTATATTGACTATGAAACACCAGAAAATGAAAAAGAATTAATTAATTCATTGAAAAATTATGTTTCCAATATAAAATA
TTTGGGGAGCTCCAATATCTTTTCAAAATTTTTATAG

Upstream 100 bases:

>100_bases
ATATTCAAAAATAAAGGGCAATTTTTGTATATTGAATTAAAAAAGCAGGAGTGATTTATTATAAAATAAATAATAATAGT
AAATAATAATTGGTGGATTT

Downstream 100 bases:

>100_bases
TTAATTTTGGGAGCTCCCTTAGAATATCAATTATTTATATTAATAAGTTGCCAATGGCAAGAATTAACATAATTCCCATA
AATCCCAAATGAGCCGAATA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MIYCLGPKGSYTEEAAEIFSKIIKDKNIEYCNSIYEVFERVEQGNNNCYGVVPSENSIEGSVSLTMDLLLEFPVKILGEV
DININHCLIGYSKDKIKKILAHPQALAQCRKYIKKHDWETESVLSNSMAVKKVYDMKNEELGAIASKKAGKLYNLNILDT
NIQDYPNNTTRFILIGKDCEDSNDISFTNNDTTKKSTIIIELIGNKPGALYNILKEFNKKNINLTRIESRPSKTKLGSYI
FYIDYETPENEKELINSLKNYVSNIKYLGSSNIFSKFL

Sequences:

>Translated_278_residues
MIYCLGPKGSYTEEAAEIFSKIIKDKNIEYCNSIYEVFERVEQGNNNCYGVVPSENSIEGSVSLTMDLLLEFPVKILGEV
DININHCLIGYSKDKIKKILAHPQALAQCRKYIKKHDWETESVLSNSMAVKKVYDMKNEELGAIASKKAGKLYNLNILDT
NIQDYPNNTTRFILIGKDCEDSNDISFTNNDTTKKSTIIIELIGNKPGALYNILKEFNKKNINLTRIESRPSKTKLGSYI
FYIDYETPENEKELINSLKNYVSNIKYLGSSNIFSKFL
>Mature_278_residues
MIYCLGPKGSYTEEAAEIFSKIIKDKNIEYCNSIYEVFERVEQGNNNCYGVVPSENSIEGSVSLTMDLLLEFPVKILGEV
DININHCLIGYSKDKIKKILAHPQALAQCRKYIKKHDWETESVLSNSMAVKKVYDMKNEELGAIASKKAGKLYNLNILDT
NIQDYPNNTTRFILIGKDCEDSNDISFTNNDTTKKSTIIIELIGNKPGALYNILKEFNKKNINLTRIESRPSKTKLGSYI
FYIDYETPENEKELINSLKNYVSNIKYLGSSNIFSKFL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=30.7971014492754, Blast_Score=131, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324013, Length=293, Percent_Identity=25.938566552901, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31654; Mature: 31654

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYCLGPKGSYTEEAAEIFSKIIKDKNIEYCNSIYEVFERVEQGNNNCYGVVPSENSIEG
CEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SVSLTMDLLLEFPVKILGEVDININHCLIGYSKDKIKKILAHPQALAQCRKYIKKHDWET
HHHHHHHHHHHCCHHHHCEECCEEEEEEEECCHHHHHHHHHCHHHHHHHHHHHHHCCCCH
ESVLSNSMAVKKVYDMKNEELGAIASKKAGKLYNLNILDTNIQDYPNNTTRFILIGKDCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
DSNDISFTNNDTTKKSTIIIELIGNKPGALYNILKEFNKKNINLTRIESRPSKTKLGSYI
CCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEE
FYIDYETPENEKELINSLKNYVSNIKYLGSSNIFSKFL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MIYCLGPKGSYTEEAAEIFSKIIKDKNIEYCNSIYEVFERVEQGNNNCYGVVPSENSIEG
CEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SVSLTMDLLLEFPVKILGEVDININHCLIGYSKDKIKKILAHPQALAQCRKYIKKHDWET
HHHHHHHHHHHCCHHHHCEECCEEEEEEEECCHHHHHHHHHCHHHHHHHHHHHHHCCCCH
ESVLSNSMAVKKVYDMKNEELGAIASKKAGKLYNLNILDTNIQDYPNNTTRFILIGKDCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
DSNDISFTNNDTTKKSTIIIELIGNKPGALYNILKEFNKKNINLTRIESRPSKTKLGSYI
CCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEE
FYIDYETPENEKELINSLKNYVSNIKYLGSSNIFSKFL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]