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The map label for this gene is 150400852

Identifier: 150400852

GI number: 150400852

Start: 439434

End: 440483

Strand: Direct

Name: 150400852

Synonym: Maeo_0420

Alternate gene names: NA

Gene position: 439434-440483 (Clockwise)

Preceding gene: 150400851

Following gene: 150400853

Centisome position: 28.0

GC content: 31.62

Gene sequence:

>1050_bases
ATGAAAAAAATAAAAATAGAAAATAAATATATTGGTGAAAATGAGCCAGTGTTTATAATAGCAGAGGCAGGGGTTAATCA
CAATGGAGATATTGAGCTCGCAAAAAAATTAATTGATATTGCATCAGAATGTGGTGCTGATGCCGTGAAATTTCAGACAT
TTAAAGCTGAAAAGGTAGTTTCAAAAAGAGCTCCGAAAGCAGAGTATCAAACTAAAAATACAGGAACTGATGAGAGTCAG
TATGAAATGATAAAGGAGCTCGAATTAACAGAAGATGATTTTTATGAATTATACAAATATTCTAAAAATAAAAATATAAT
GTTTTTATCTACACCATTTGATTTTGAAAGTGCTGATTATTTAGACGAATTAATGCCATTATTTAAAATATCATCAACTG
ATTTAAACAATTTACCATTTTTGGAATATATCGCAAAAAAGAAAAAGCCTATAATACTATCCACTGGAATGGGGACATTG
GGGGAAATAGATGAAGCTATAAACATCATAAAGAAAGCAAACAATAATGATATAATATTGCTACACTGTGTCACAAACTA
TCCAGCTAGTTTTGAAAGTTTGAATTTGAGAGTTATTAGAACATTAAAAGAAGCATTTAAACTACCTGTTGGTTTTTCAG
ACCATAGCTTAGGAATTTATGCCCCAATAAGTGCGGTATCTCTCGGAGCTACTGTTATTGAGAAGCATTTTACATTAGAT
AAAAATCTACCGGGTCCTGACCATAAGGCATCCCTAAGCCCCGAAGAATTAAAAGAAATGGTAAGTGCAATCCGTTCAAT
TGAAAAAGCATTGGGAAATGGTATAAAAAGACCCACCTCCGAAGAAGAGAAAATTAAAAAAGTTGCAAGAAGAAGTTTAG
TAGCAAATGTTGATATTCCAAAAGGGGCGACAATCAAAAAAGAAATGATAGTCATAAAAAGACCAGGAACGGGGATTGAG
CCAAAGTATTTAAATGAAATTATGGGGAAAAAGGTAAAAAGAGATATCAAAATAGATGAGATTTTAAAATTAGGTGATAT
AGAATGGTAA

Upstream 100 bases:

>100_bases
AAATTTGATAAATTACCATTGTGTAAAAAATGTATTGATCCAATCGCACATTCATTATACATGCCAATAAAAATAAAAGA
GAATATAATATGTGGTAAAT

Downstream 100 bases:

>100_bases
AAATTTTAAGAACAGCAACTGGATGCATGGCATCGATTAGTTTTATCAATGAATTAATGAAAAAGGGTGTTGAGGTTGTA
TGTGTTGATGCAAATCCTAT

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKKIKIENKYIGENEPVFIIAEAGVNHNGDIELAKKLIDIASECGADAVKFQTFKAEKVVSKRAPKAEYQTKNTGTDESQ
YEMIKELELTEDDFYELYKYSKNKNIMFLSTPFDFESADYLDELMPLFKISSTDLNNLPFLEYIAKKKKPIILSTGMGTL
GEIDEAINIIKKANNNDIILLHCVTNYPASFESLNLRVIRTLKEAFKLPVGFSDHSLGIYAPISAVSLGATVIEKHFTLD
KNLPGPDHKASLSPEELKEMVSAIRSIEKALGNGIKRPTSEEEKIKKVARRSLVANVDIPKGATIKKEMIVIKRPGTGIE
PKYLNEIMGKKVKRDIKIDEILKLGDIEW

Sequences:

>Translated_349_residues
MKKIKIENKYIGENEPVFIIAEAGVNHNGDIELAKKLIDIASECGADAVKFQTFKAEKVVSKRAPKAEYQTKNTGTDESQ
YEMIKELELTEDDFYELYKYSKNKNIMFLSTPFDFESADYLDELMPLFKISSTDLNNLPFLEYIAKKKKPIILSTGMGTL
GEIDEAINIIKKANNNDIILLHCVTNYPASFESLNLRVIRTLKEAFKLPVGFSDHSLGIYAPISAVSLGATVIEKHFTLD
KNLPGPDHKASLSPEELKEMVSAIRSIEKALGNGIKRPTSEEEKIKKVARRSLVANVDIPKGATIKKEMIVIKRPGTGIE
PKYLNEIMGKKVKRDIKIDEILKLGDIEW
>Mature_349_residues
MKKIKIENKYIGENEPVFIIAEAGVNHNGDIELAKKLIDIASECGADAVKFQTFKAEKVVSKRAPKAEYQTKNTGTDESQ
YEMIKELELTEDDFYELYKYSKNKNIMFLSTPFDFESADYLDELMPLFKISSTDLNNLPFLEYIAKKKKPIILSTGMGTL
GEIDEAINIIKKANNNDIILLHCVTNYPASFESLNLRVIRTLKEAFKLPVGFSDHSLGIYAPISAVSLGATVIEKHFTLD
KNLPGPDHKASLSPEELKEMVSAIRSIEKALGNGIKRPTSEEEKIKKVARRSLVANVDIPKGATIKKEMIVIKRPGTGIE
PKYLNEIMGKKVKRDIKIDEILKLGDIEW

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=339, Percent_Identity=37.1681415929204, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21357081, Length=252, Percent_Identity=35.7142857142857, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 39213; Mature: 39213

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKIENKYIGENEPVFIIAEAGVNHNGDIELAKKLIDIASECGADAVKFQTFKAEKVV
CCCEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SKRAPKAEYQTKNTGTDESQYEMIKELELTEDDFYELYKYSKNKNIMFLSTPFDFESADY
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
LDELMPLFKISSTDLNNLPFLEYIAKKKKPIILSTGMGTLGEIDEAINIIKKANNNDIIL
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEE
LHCVTNYPASFESLNLRVIRTLKEAFKLPVGFSDHSLGIYAPISAVSLGATVIEKHFTLD
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCC
KNLPGPDHKASLSPEELKEMVSAIRSIEKALGNGIKRPTSEEEKIKKVARRSLVANVDIP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEECCCC
KGATIKKEMIVIKRPGTGIEPKYLNEIMGKKVKRDIKIDEILKLGDIEW
CCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKKIKIENKYIGENEPVFIIAEAGVNHNGDIELAKKLIDIASECGADAVKFQTFKAEKVV
CCCEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SKRAPKAEYQTKNTGTDESQYEMIKELELTEDDFYELYKYSKNKNIMFLSTPFDFESADY
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
LDELMPLFKISSTDLNNLPFLEYIAKKKKPIILSTGMGTLGEIDEAINIIKKANNNDIIL
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEE
LHCVTNYPASFESLNLRVIRTLKEAFKLPVGFSDHSLGIYAPISAVSLGATVIEKHFTLD
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCC
KNLPGPDHKASLSPEELKEMVSAIRSIEKALGNGIKRPTSEEEKIKKVARRSLVANVDIP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEECCCC
KGATIKKEMIVIKRPGTGIEPKYLNEIMGKKVKRDIKIDEILKLGDIEW
CCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]