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The map label for this gene is hldE [H]

Identifier: 150400832

GI number: 150400832

Start: 415002

End: 415910

Strand: Reverse

Name: hldE [H]

Synonym: Maeo_0400

Alternate gene names: 150400832

Gene position: 415910-415002 (Counterclockwise)

Preceding gene: 150400833

Following gene: 150400831

Centisome position: 26.5

GC content: 30.91

Gene sequence:

>909_bases
ATGATTTGTGTTTTGGGGGATATAATGCTTGATAAATATACCTATGGAAAAGTTGAAAGAATAAATCCAGAAGCTCCTGT
GCCAGTATTACAGGTGGTTGAAGAAAAATACGCCATTGGGGGAGCAGGAAATGTTGCAAACAATATAGTATCGTTAAAAG
AATCCGTTGTGTTGATGGGCATATATAATAAAAATGATTATTTTGGAAAACAAATTATGGAATTATGTAATAAAATGAAT
ATAAATTCATTTTTTGTATCTGATGGAAGACCCACCATTGTAAAACATAGGTTTGTAGCATTGGGATATAATCAGCAACT
TATAAGGGTAGATTATGAAGAAAAACATAATATTGGGAACAAATATATAAAATTATTTGTCGATAAAATTTTAGAATTAA
ATCCGGATATATTAATAATTTCAGACTATGCAAAGGGATTAGTTACAGAAGAATTGATGGAGCTCCTAAAAAAACAATTT
AAAGGCAAAATATTAATGGACCCAAAACCAGAAAATATTGCCTTGTGCAAAAATGTGTTTTTAATAAAACCAAATTTAAA
AGAGGCTTCAGGAATCGTTGGAAGAGAAATAAAAAACAACGATAAAGATGTTGAAAAAGCAGGTATGGAAATTGTAGATA
ACTATAATGCAAATGTAGTAATTACAAGAAGTGAAAAAGGTTCAACGCTAATTACCAAAGATAAAAAAATATATCATATT
CCAACAGAGGTCATGGAGCTCCACGATGTTTCTGGTGCAGGAGATACATATATAGCAACAATTGGCTATGCTCTTGACAA
AGGGCATGATTTAATAGATGCCGTTAAATTGGCAAATAAGGCGAGCTCAATAGTAGTTGGAAAAATAGGAACTGCAACAG
TTAATTTGGAGGAGTTATTTAATGAATAA

Upstream 100 bases:

>100_bases
CCACAACTACCGTAATTGAATGGGTTTTGGAAAAATATAAATCTTAATAATTTTAATTGATTAAGAAACAACTTTTAAAA
ACTATAAAAGGAGGTAAAAA

Downstream 100 bases:

>100_bases
TCCAGCAAATAAAGCCATATTTCTTGATAGGGATGGAGTCATAAATAAAAAACTTGAAGGAGATTATGTTAAATCCACTG
ATGAGTTTGAATTGCTACCA

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MICVLGDIMLDKYTYGKVERINPEAPVPVLQVVEEKYAIGGAGNVANNIVSLKESVVLMGIYNKNDYFGKQIMELCNKMN
INSFFVSDGRPTIVKHRFVALGYNQQLIRVDYEEKHNIGNKYIKLFVDKILELNPDILIISDYAKGLVTEELMELLKKQF
KGKILMDPKPENIALCKNVFLIKPNLKEASGIVGREIKNNDKDVEKAGMEIVDNYNANVVITRSEKGSTLITKDKKIYHI
PTEVMELHDVSGAGDTYIATIGYALDKGHDLIDAVKLANKASSIVVGKIGTATVNLEELFNE

Sequences:

>Translated_302_residues
MICVLGDIMLDKYTYGKVERINPEAPVPVLQVVEEKYAIGGAGNVANNIVSLKESVVLMGIYNKNDYFGKQIMELCNKMN
INSFFVSDGRPTIVKHRFVALGYNQQLIRVDYEEKHNIGNKYIKLFVDKILELNPDILIISDYAKGLVTEELMELLKKQF
KGKILMDPKPENIALCKNVFLIKPNLKEASGIVGREIKNNDKDVEKAGMEIVDNYNANVVITRSEKGSTLITKDKKIYHI
PTEVMELHDVSGAGDTYIATIGYALDKGHDLIDAVKLANKASSIVVGKIGTATVNLEELFNE
>Mature_302_residues
MICVLGDIMLDKYTYGKVERINPEAPVPVLQVVEEKYAIGGAGNVANNIVSLKESVVLMGIYNKNDYFGKQIMELCNKMN
INSFFVSDGRPTIVKHRFVALGYNQQLIRVDYEEKHNIGNKYIKLFVDKILELNPDILIISDYAKGLVTEELMELLKKQF
KGKILMDPKPENIALCKNVFLIKPNLKEASGIVGREIKNNDKDVEKAGMEIVDNYNANVVITRSEKGSTLITKDKKIYHI
PTEVMELHDVSGAGDTYIATIGYALDKGHDLIDAVKLANKASSIVVGKIGTATVNLEELFNE

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=306, Percent_Identity=38.562091503268, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 33699; Mature: 33699

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICVLGDIMLDKYTYGKVERINPEAPVPVLQVVEEKYAIGGAGNVANNIVSLKESVVLMG
CEEEEECHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEE
IYNKNDYFGKQIMELCNKMNINSFFVSDGRPTIVKHRFVALGYNQQLIRVDYEEKHNIGN
EECCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECCCCEEEEECCHHHHCCHH
KYIKLFVDKILELNPDILIISDYAKGLVTEELMELLKKQFKGKILMDPKPENIALCKNVF
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECEEE
LIKPNLKEASGIVGREIKNNDKDVEKAGMEIVDNYNANVVITRSEKGSTLITKDKKIYHI
EECCCCHHHCCCCCCHHCCCCCHHHHHCHHHEECCCCCEEEEECCCCCEEEECCCEEEEC
PTEVMELHDVSGAGDTYIATIGYALDKGHDLIDAVKLANKASSIVVGKIGTATVNLEELF
CHHHHHHHCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCCEEEEEECCCEEEEHHHHH
NE
CC
>Mature Secondary Structure
MICVLGDIMLDKYTYGKVERINPEAPVPVLQVVEEKYAIGGAGNVANNIVSLKESVVLMG
CEEEEECHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEE
IYNKNDYFGKQIMELCNKMNINSFFVSDGRPTIVKHRFVALGYNQQLIRVDYEEKHNIGN
EECCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECCCCEEEEECCHHHHCCHH
KYIKLFVDKILELNPDILIISDYAKGLVTEELMELLKKQFKGKILMDPKPENIALCKNVF
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECEEE
LIKPNLKEASGIVGREIKNNDKDVEKAGMEIVDNYNANVVITRSEKGSTLITKDKKIYHI
EECCCCHHHCCCCCCHHCCCCCHHHHHCHHHEECCCCCEEEEECCCCCEEEECCCEEEEC
PTEVMELHDVSGAGDTYIATIGYALDKGHDLIDAVKLANKASSIVVGKIGTATVNLEELF
CHHHHHHHCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCCEEEEEECCCEEEEHHHHH
NE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA