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The map label for this gene is ahpC [C]

Identifier: 150400760

GI number: 150400760

Start: 349250

End: 349930

Strand: Reverse

Name: ahpC [C]

Synonym: Maeo_0326

Alternate gene names: 150400760

Gene position: 349930-349250 (Counterclockwise)

Preceding gene: 150400761

Following gene: 150400759

Centisome position: 22.3

GC content: 36.42

Gene sequence:

>681_bases
ATGCATGAAGATATATGTTGCATTGGAGAATATAAAATGCCATTAATAGGTGAGAAATTCCCTGAAGTAGAAGTTAAAAC
TACACAAGGAGCAATAAAATTACCGGAACACTTTGAAGGTAAATGGTTTGTTTTATTTAGTCATCCTGCGGACTTTACAC
CAGTTTGCACCACTGAATTTGTGGCATTTCAAAATAGATATGACCAATTTAAGGAGCTAAATACTGAATTAATAGGTTTA
AGTATAGACCAGGTATTCAGCCATTTAAAATGGATTGAGTGGATAAAGGATAATTTGGATGTTGATATTGAATTCCCAGT
AGTCGCAGATGATAGGGGACAGTTGGCTGAAAGATTAGGTATGGTGAGCCCATATAAAGGTAATAACACAGTTAGAGCTG
TATTTATTGTAGATGATAAGGGAGCAATTAGGGCAATATTATATTATCCACAGGAAGCTGGAAGAAATATCGATGAAATA
ATAAGATTAGTTAAAGCACTTCAAACATCCGATAAAGGAGTGGCGCTTCCAGCAAACTGGCCCAACAATGAGATTATTGG
GGATAAAGTAATAGTCCCCCCTGCTTCCACGGTTGAAGAAATGAAGAGTAGAAAGGAAGCCGCTGAAAAAGGAGAAATAG
AATGCCTTGATTGGTGGCTTTGCTGTAAAAAATTGGAATAA

Upstream 100 bases:

>100_bases
ATGTCAAGGTTATGACCCAAAATTGGTTGCAAGGACACCGAATAATGAAAGTAAATTTTAATTAAAATTAAAAAACATAA
AAATATTGGGGGGATAAATT

Downstream 100 bases:

>100_bases
ATTAATTAATTATCCTACTTTTTATTTTATATTCAGATTATTACTCTGTAATTTTTTGGGAATATGTGGATTGGACTGAG
GTATAAATATGGACGAAACA

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MHEDICCIGEYKMPLIGEKFPEVEVKTTQGAIKLPEHFEGKWFVLFSHPADFTPVCTTEFVAFQNRYDQFKELNTELIGL
SIDQVFSHLKWIEWIKDNLDVDIEFPVVADDRGQLAERLGMVSPYKGNNTVRAVFIVDDKGAIRAILYYPQEAGRNIDEI
IRLVKALQTSDKGVALPANWPNNEIIGDKVIVPPASTVEEMKSRKEAAEKGEIECLDWWLCCKKLE

Sequences:

>Translated_226_residues
MHEDICCIGEYKMPLIGEKFPEVEVKTTQGAIKLPEHFEGKWFVLFSHPADFTPVCTTEFVAFQNRYDQFKELNTELIGL
SIDQVFSHLKWIEWIKDNLDVDIEFPVVADDRGQLAERLGMVSPYKGNNTVRAVFIVDDKGAIRAILYYPQEAGRNIDEI
IRLVKALQTSDKGVALPANWPNNEIIGDKVIVPPASTVEEMKSRKEAAEKGEIECLDWWLCCKKLE
>Mature_226_residues
MHEDICCIGEYKMPLIGEKFPEVEVKTTQGAIKLPEHFEGKWFVLFSHPADFTPVCTTEFVAFQNRYDQFKELNTELIGL
SIDQVFSHLKWIEWIKDNLDVDIEFPVVADDRGQLAERLGMVSPYKGNNTVRAVFIVDDKGAIRAILYYPQEAGRNIDEI
IRLVKALQTSDKGVALPANWPNNEIIGDKVIVPPASTVEEMKSRKEAAEKGEIECLDWWLCCKKLE

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=198, Percent_Identity=37.8787878787879, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI5453549, Length=152, Percent_Identity=39.4736842105263, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI4505591, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI32455266, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI32455264, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI32189392, Length=158, Percent_Identity=38.6075949367089, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI5802974, Length=145, Percent_Identity=36.551724137931, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI32483377, Length=145, Percent_Identity=36.551724137931, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI33188454, Length=56, Percent_Identity=50, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786822, Length=148, Percent_Identity=31.7567567567568, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554494, Length=147, Percent_Identity=36.734693877551, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25153706, Length=198, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193204376, Length=152, Percent_Identity=38.1578947368421, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI32565831, Length=152, Percent_Identity=38.1578947368421, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319407, Length=198, Percent_Identity=41.9191919191919, Blast_Score=141, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=177, Percent_Identity=36.1581920903955, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320661, Length=147, Percent_Identity=35.3741496598639, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17975518, Length=195, Percent_Identity=40.5128205128205, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24652434, Length=195, Percent_Identity=40.5128205128205, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24652436, Length=195, Percent_Identity=40, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24581278, Length=193, Percent_Identity=39.8963730569948, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24656348, Length=147, Percent_Identity=37.4149659863946, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17864676, Length=147, Percent_Identity=37.4149659863946, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17738015, Length=151, Percent_Identity=37.7483443708609, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17157991, Length=151, Percent_Identity=39.0728476821192, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641739, Length=151, Percent_Identity=39.0728476821192, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357347, Length=145, Percent_Identity=35.1724137931034, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25790; Mature: 25790

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEDICCIGEYKMPLIGEKFPEVEVKTTQGAIKLPEHFEGKWFVLFSHPADFTPVCTTEF
CCCCEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCCCHHHHH
VAFQNRYDQFKELNTELIGLSIDQVFSHLKWIEWIKDNLDVDIEFPVVADDRGQLAERLG
HHHHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHC
MVSPYKGNNTVRAVFIVDDKGAIRAILYYPQEAGRNIDEIIRLVKALQTSDKGVALPANW
CCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEECCCC
PNNEIIGDKVIVPPASTVEEMKSRKEAAEKGEIECLDWWLCCKKLE
CCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCC
>Mature Secondary Structure
MHEDICCIGEYKMPLIGEKFPEVEVKTTQGAIKLPEHFEGKWFVLFSHPADFTPVCTTEF
CCCCEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCCCHHHHH
VAFQNRYDQFKELNTELIGLSIDQVFSHLKWIEWIKDNLDVDIEFPVVADDRGQLAERLG
HHHHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHC
MVSPYKGNNTVRAVFIVDDKGAIRAILYYPQEAGRNIDEIIRLVKALQTSDKGVALPANW
CCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEECCCC
PNNEIIGDKVIVPPASTVEEMKSRKEAAEKGEIECLDWWLCCKKLE
CCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]