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The map label for this gene is hflC [H]

Identifier: 150400689

GI number: 150400689

Start: 280097

End: 281029

Strand: Direct

Name: hflC [H]

Synonym: Maeo_0253

Alternate gene names: 150400689

Gene position: 280097-281029 (Clockwise)

Preceding gene: 150400685

Following gene: 150400691

Centisome position: 17.85

GC content: 31.19

Gene sequence:

>933_bases
TTGTCATATATTTATAGTATATTCTATATATTTTATTTATCATATATCTTATTTATATCTTATTCACATATTGGCGTTTA
TGTATCTTATTATCTAATTTTTTTTAATTTATATGGTGATATATTGGCAAATTATAGGATTATAATAATACTGGGTGTTG
TATTAATGGGGGCTTCGCTTTTCTCCTCCTATTATATTATAGATAGCACCGAAGTAGGAATTGTAAAAACATTTGGGAAA
GTAAATCCTGAACCAGTAGAATCAGGCATACATTTTAAAATTCCGATTGTACAGGATGTTGTAAGAATGAATATTTATGA
AAAAAATATGGATATGGTTGAAAATAACGGAAATGCCGTTAAAGTTCTTACGCGAGAGGGGCTCCCCGTGGTTATTGATT
TATCTGTGCAATATAAAATAAATCCAAAATATGCACCAGAATTATATTTAAGTGTTAAAAATCCAGAACCATGGATGACC
AGTAGAATAAGGGCAAAGGTTAGAGATATAATTTCAGAATATAGCACTGATGAGCTTTACGGAGAGAAACGAACAGAGGT
TCAGCAAAAAATAAACACAGAAATTGATAAAGAATTTAATGATAAAGGCATAATAGTTACAGCAGTTCTTATTAGAAATA
TTGACCTTCCCCAACAGGTTGAACAGGCAATTGAGCGAAAAATGAAATCTAAGCAAGAAGCTGAACAGATGAAATATGAA
GTTCAAAGAGCCAAAACAGAGGCCGAAAAGAAAATCGTAGAGGCACAAGGGCAGGCGAATGCTACAAGAATATTGGCAAA
AGCAATAAGGGAAAATCCCGAAATATTAGAGTATAAGAAATTAGATGCTTTAAAAGAGATGGCCTCAAATGATAATAAGG
TATTTATTGTGCCGAGCTCTAATGATTTGATATTAAATGTAGATAATAAATAA

Upstream 100 bases:

>100_bases
TTGATTTTTGTAGATTTTCCGGTTCCACTCAAAAACATACCACATATTTTAAATTTTATATATTTCATTATATTGTCATA
TATTTATAGTATATTTTATA

Downstream 100 bases:

>100_bases
AGTCCTTTTTATTATATTTATATATACATTAATTTTCTATTTTTAAATTATTTTAAATATATATTATTTTAGTTAATTTA
TTAGTTATAATACAGGAGCT

Product: band 7 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSYIYSIFYIFYLSYILFISYSHIGVYVSYYLIFFNLYGDILANYRIIIILGVVLMGASLFSSYYIIDSTEVGIVKTFGK
VNPEPVESGIHFKIPIVQDVVRMNIYEKNMDMVENNGNAVKVLTREGLPVVIDLSVQYKINPKYAPELYLSVKNPEPWMT
SRIRAKVRDIISEYSTDELYGEKRTEVQQKINTEIDKEFNDKGIIVTAVLIRNIDLPQQVEQAIERKMKSKQEAEQMKYE
VQRAKTEAEKKIVEAQGQANATRILAKAIRENPEILEYKKLDALKEMASNDNKVFIVPSSNDLILNVDNK

Sequences:

>Translated_310_residues
MSYIYSIFYIFYLSYILFISYSHIGVYVSYYLIFFNLYGDILANYRIIIILGVVLMGASLFSSYYIIDSTEVGIVKTFGK
VNPEPVESGIHFKIPIVQDVVRMNIYEKNMDMVENNGNAVKVLTREGLPVVIDLSVQYKINPKYAPELYLSVKNPEPWMT
SRIRAKVRDIISEYSTDELYGEKRTEVQQKINTEIDKEFNDKGIIVTAVLIRNIDLPQQVEQAIERKMKSKQEAEQMKYE
VQRAKTEAEKKIVEAQGQANATRILAKAIRENPEILEYKKLDALKEMASNDNKVFIVPSSNDLILNVDNK
>Mature_309_residues
SYIYSIFYIFYLSYILFISYSHIGVYVSYYLIFFNLYGDILANYRIIIILGVVLMGASLFSSYYIIDSTEVGIVKTFGKV
NPEPVESGIHFKIPIVQDVVRMNIYEKNMDMVENNGNAVKVLTREGLPVVIDLSVQYKINPKYAPELYLSVKNPEPWMTS
RIRAKVRDIISEYSTDELYGEKRTEVQQKINTEIDKEFNDKGIIVTAVLIRNIDLPQQVEQAIERKMKSKQEAEQMKYEV
QRAKTEAEKKIVEAQGQANATRILAKAIRENPEILEYKKLDALKEMASNDNKVFIVPSSNDLILNVDNK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005854, Length=288, Percent_Identity=22.9166666666667, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI221307584, Length=288, Percent_Identity=22.9166666666667, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193205005, Length=252, Percent_Identity=23.015873015873, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321571, Length=262, Percent_Identity=23.2824427480916, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161077244, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077238, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077236, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077234, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077240, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077242, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24585145, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585147, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573263, Length=263, Percent_Identity=23.1939163498099, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 35719; Mature: 35588

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYIYSIFYIFYLSYILFISYSHIGVYVSYYLIFFNLYGDILANYRIIIILGVVLMGASL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FSSYYIIDSTEVGIVKTFGKVNPEPVESGIHFKIPIVQDVVRMNIYEKNMDMVENNGNAV
HHCEEEEECCCCCHHHHHCCCCCCHHCCCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCEE
KVLTREGLPVVIDLSVQYKINPKYAPELYLSVKNPEPWMTSRIRAKVRDIISEYSTDELY
EEEEECCCCEEEEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHC
GEKRTEVQQKINTEIDKEFNDKGIIVTAVLIRNIDLPQQVEQAIERKMKSKQEAEQMKYE
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQRAKTEAEKKIVEAQGQANATRILAKAIRENPEILEYKKLDALKEMASNDNKVFIVPSS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
NDLILNVDNK
CCEEEEECCC
>Mature Secondary Structure 
SYIYSIFYIFYLSYILFISYSHIGVYVSYYLIFFNLYGDILANYRIIIILGVVLMGASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FSSYYIIDSTEVGIVKTFGKVNPEPVESGIHFKIPIVQDVVRMNIYEKNMDMVENNGNAV
HHCEEEEECCCCCHHHHHCCCCCCHHCCCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCEE
KVLTREGLPVVIDLSVQYKINPKYAPELYLSVKNPEPWMTSRIRAKVRDIISEYSTDELY
EEEEECCCCEEEEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHC
GEKRTEVQQKINTEIDKEFNDKGIIVTAVLIRNIDLPQQVEQAIERKMKSKQEAEQMKYE
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQRAKTEAEKKIVEAQGQANATRILAKAIRENPEILEYKKLDALKEMASNDNKVFIVPSS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
NDLILNVDNK
CCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]