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The map label for this gene is tbp

Identifier: 150400624

GI number: 150400624

Start: 203479

End: 204024

Strand: Reverse

Name: tbp

Synonym: Maeo_0186

Alternate gene names: 150400624

Gene position: 204024-203479 (Counterclockwise)

Preceding gene: 150400625

Following gene: 150400623

Centisome position: 13.0

GC content: 32.78

Gene sequence:

>546_bases
ATGAGCTCCGAAATAAAAATTGTAAATGTTGTAGTCTCCACAAAAATAGGGGACGATATCGACTTAGAATATGTTGCAGA
TGTTCTTGATAATTCAGAATATGAACCAGAGCAATTCCCTGGATTAGTTTGTAGATTAAGTGACCCAAAAGTTGCATTAT
TAATATTTAGAAGTGGTAAATTAAACTGCACTGGTGCAAAAAGCAAAGAAGATGCAGTAATTGCAATAAACAAAGTTATG
GAATATTTAAGAGAAGCTGGATTAGATTTAATTGATACTCCCGAGGTAAAAGTTCAAAATATGGTGGCTACTGCGGAGCT
CGGTATGGAACCTAATTTAGATGACTTATCTACTCTTGAAAGAACAGAATATGAACCAGAGCAATTCCCCGGATTAGTTT
ATAGAATGGAATCTCCAAAAGTTGTATTATTGGTATTTGGCAGTGGAAAAGTTGTTATAACGGGATTAAAAAATAAAGAA
GATGCATACATTGCCCTTGAAAAAATAAAAAATACAGTGAAAGAACTTGAAGAAGAATATTTTTAA

Upstream 100 bases:

>100_bases
ATTAAATATATATGTAGATATTATACCGATATTTATATAATACCTTTATATACTATATATACTATATAAATAAAATATTA
TAAAATATAGGTGAGATATT

Downstream 100 bases:

>100_bases
GTGATATTGTGATTGCTATAATTGACTACAATGCAGGGAATTTAAGAAGCATAAAAAAGGCCGTTGAATTATATTCTAAT
AACATAGTAATTACCAACGA

Product: transcription factor

Products: NA

Alternate protein names: Box A-binding protein; BAP; TATA sequence-binding protein; TBP; TATA-box factor

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGKLNCTGAKSKEDAVIAINKVM
EYLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLERTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKE
DAYIALEKIKNTVKELEEEYF

Sequences:

>Translated_181_residues
MSSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGKLNCTGAKSKEDAVIAINKVM
EYLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLERTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKE
DAYIALEKIKNTVKELEEEYF
>Mature_180_residues
SSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGKLNCTGAKSKEDAVIAINKVME
YLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLERTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKED
AYIALEKIKNTVKELEEEYF

Specific function: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation

COG id: COG2101

COG function: function code K; TATA-box binding protein (TBP), component of TFIID and TFIIIB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TBP family

Homologues:

Organism=Homo sapiens, GI285026520, Length=177, Percent_Identity=37.2881355932203, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI4507379, Length=177, Percent_Identity=37.2881355932203, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI39930602, Length=173, Percent_Identity=37.5722543352601, Blast_Score=123, Evalue=7e-29,
Organism=Homo sapiens, GI4759234, Length=178, Percent_Identity=29.7752808988764, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555358, Length=172, Percent_Identity=40.1162790697674, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320996, Length=172, Percent_Identity=39.5348837209302, Blast_Score=128, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136834, Length=169, Percent_Identity=39.6449704142012, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI17647997, Length=178, Percent_Identity=36.5168539325843, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TBP_META3 (A6UTF6)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324390.1
- ProteinModelPortal:   A6UTF6
- SMR:   A6UTF6
- STRING:   A6UTF6
- GeneID:   5327035
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0186
- eggNOG:   arNOG09331
- HOGENOM:   HBG499930
- OMA:   MERSVPN
- ProtClustDB:   PRK00394
- BioCyc:   MAEO419665:MAEO_0186-MONOMER
- HAMAP:   MF_00408
- InterPro:   IPR012295
- InterPro:   IPR000814
- InterPro:   IPR012294
- Gene3D:   G3DSA:3.30.310.10
- PANTHER:   PTHR10126
- PRINTS:   PR00686

Pfam domain/function: PF00352 TBP; SSF55945 TFIID_C/glycos_N

EC number: NA

Molecular weight: Translated: 20209; Mature: 20078

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS00351 TFIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGK
CCCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEECCC
LNCTGAKSKEDAVIAINKVMEYLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLE
EEECCCCCCCCCEEEHHHHHHHHHHCCCCEECCCCCHHHHEEEHHHCCCCCCCHHHHHHH
RTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKEDAYIALEKIKNTVKELEEEY
HCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
F
C
>Mature Secondary Structure 
SSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGK
CCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEECCC
LNCTGAKSKEDAVIAINKVMEYLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLE
EEECCCCCCCCCEEEHHHHHHHHHHCCCCEECCCCCHHHHEEEHHHCCCCCCCHHHHHHH
RTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKEDAYIALEKIKNTVKELEEEY
HCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA