Click here to switch to the map view.

The map label for this gene is ribH

Identifier: 150400606

GI number: 150400606

Start: 186627

End: 187037

Strand: Direct

Name: ribH

Synonym: Maeo_0168

Alternate gene names: 150400606

Gene position: 186627-187037 (Clockwise)

Preceding gene: 150400605

Following gene: 150400607

Centisome position: 11.89

GC content: 34.55

Gene sequence:

>411_bases
ATGGTAAAATTGGGATTTGTTATAGCTGAATTTAACAGAGATATAACTTTTATGATGGAAAAACTTGCAGATGAACATGC
TGAGTTTTTGGGTGCAGAAGTCCCCTATAAAGTAATGGTTCCGGGAGTTTATGATATGCCCGTACCAATAAAAAGATTGT
TGGAAAAAGAGGATGTTGATGCAGTAATCACAATAGGTTGCGTAATAGAAGGAGACACAGAACATGATGAAATAGTTGTT
CATAATGCAGCAAGGAAAATTACAGATTTATCATTACAATATGACAAACCTGTTGCACTTGGAATATCCGGTCCAGGAAT
GACAAGAATGCAGGCAGAAAGAAGAATAGATTATGGTAGAAAAGCTGTTGAATCGGCTGTAAAAATGGTTAAAAGATTAA
ATGATTTATAA

Upstream 100 bases:

>100_bases
ATTGTTGCAGATTTAATTAATAAACATATTAATAATATATAATTGAAACATATAATTAAATATAAGAAAAATGTGAAAAA
CTATATAAAAAGGTGTAATC

Downstream 100 bases:

>100_bases
TTTTTCATATTTTTCGTTTTAAATAATTTTTTACCTTATTATATTATTGTATTTTTATATTATTTTTATTTAGGTGTGTG
ATAATATGGATATTTTAAAA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MVKLGFVIAEFNRDITFMMEKLADEHAEFLGAEVPYKVMVPGVYDMPVPIKRLLEKEDVDAVITIGCVIEGDTEHDEIVV
HNAARKITDLSLQYDKPVALGISGPGMTRMQAERRIDYGRKAVESAVKMVKRLNDL

Sequences:

>Translated_136_residues
MVKLGFVIAEFNRDITFMMEKLADEHAEFLGAEVPYKVMVPGVYDMPVPIKRLLEKEDVDAVITIGCVIEGDTEHDEIVV
HNAARKITDLSLQYDKPVALGISGPGMTRMQAERRIDYGRKAVESAVKMVKRLNDL
>Mature_136_residues
MVKLGFVIAEFNRDITFMMEKLADEHAEFLGAEVPYKVMVPGVYDMPVPIKRLLEKEDVDAVITIGCVIEGDTEHDEIVV
HNAARKITDLSLQYDKPVALGISGPGMTRMQAERRIDYGRKAVESAVKMVKRLNDL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_META3 (A6UTD8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324372.1
- ProteinModelPortal:   A6UTD8
- SMR:   A6UTD8
- STRING:   A6UTD8
- GeneID:   5326642
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0168
- eggNOG:   arNOG09975
- HOGENOM:   HBG311126
- OMA:   GFVVAEF
- ProtClustDB:   PRK00061
- BioCyc:   MAEO419665:MAEO_0168-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 15263; Mature: 15263

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLGFVIAEFNRDITFMMEKLADEHAEFLGAEVPYKVMVPGVYDMPVPIKRLLEKEDVD
CEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCCC
AVITIGCVIEGDTEHDEIVVHNAARKITDLSLQYDKPVALGISGPGMTRMQAERRIDYGR
EEEEEEEEEECCCCCCEEEEEHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHHH
KAVESAVKMVKRLNDL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKLGFVIAEFNRDITFMMEKLADEHAEFLGAEVPYKVMVPGVYDMPVPIKRLLEKEDVD
CEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCCC
AVITIGCVIEGDTEHDEIVVHNAARKITDLSLQYDKPVALGISGPGMTRMQAERRIDYGR
EEEEEEEEEECCCCCCEEEEEHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHHH
KAVESAVKMVKRLNDL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA