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The map label for this gene is pyrF [H]

Identifier: 150400511

GI number: 150400511

Start: 78993

End: 79652

Strand: Direct

Name: pyrF [H]

Synonym: Maeo_0073

Alternate gene names: 150400511

Gene position: 78993-79652 (Clockwise)

Preceding gene: 150400508

Following gene: 150400512

Centisome position: 5.03

GC content: 34.39

Gene sequence:

>660_bases
ATGAAACTAATGCTTGCCTTAGATGTAATGAGTAAAAATGAAGCTTTAAAAATAGCTGAGGAAACTAAGGATTTCGTAGA
TATAATTAAAATAGGATATCCGCTTGTGCTTAGCACTGGCATAGAGATAGTAAAAGAAATAAAAAATAAAACAAATAAGG
AGGTAGTATGTGATTTTAAAGTTGCAGATATACCTGCCACAAATGAAAAAATTGCAAAAACAACTTTAAAATATGCCGAC
GCCATAATTTGTCAAGGATTTGTTGGAAAAGATAGTGTTATGGCAATTCAAAAAGTTGCAGAAGAATATGGTAATAAGGG
AGCTCCCAAAAAAGTAATAATGGTTACAGAGATGTCTCACCTAAGTGCTGTTGAATTTTTGCAACCTGTTGCCGATGACC
TTGCAAAAATGGCAAAAGAATTATCCGTTGATGGGGTGGTTGCACCATCTACTAGACCCGAACGATTAAAAGAAATAAAA
GAAATTGTTGGAGATATTCCAATCATATCCCCTGGGGTAGGGGCACAGGGCGGAGATTTGGATAAGGTATTGGAAATATT
GGGCGATAATGATTATGTTATTGTTGGAAGGGGAATATACGAGCACAATAATCCAAAGGAAAGTGCTAAACATTATAAAA
AATTGATATCTAAAAATTGA

Upstream 100 bases:

>100_bases
CACCTCTATATATTAATAGCATATATTATATAAAAAGAACAATATAATATATATGTATATTGTTATTATAATCGTATTAA
ATTAATATTGGAGGGATAAT

Downstream 100 bases:

>100_bases
TATCTATAACGGCGATATTATGAACTCTGCAAAAATATATGGCGTAGATGATGGAGTAATAGTAAATTCTATGAAAAAAG
TGTTTGAAGAGGAAATTGAT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKLMLALDVMSKNEALKIAEETKDFVDIIKIGYPLVLSTGIEIVKEIKNKTNKEVVCDFKVADIPATNEKIAKTTLKYAD
AIICQGFVGKDSVMAIQKVAEEYGNKGAPKKVIMVTEMSHLSAVEFLQPVADDLAKMAKELSVDGVVAPSTRPERLKEIK
EIVGDIPIISPGVGAQGGDLDKVLEILGDNDYVIVGRGIYEHNNPKESAKHYKKLISKN

Sequences:

>Translated_219_residues
MKLMLALDVMSKNEALKIAEETKDFVDIIKIGYPLVLSTGIEIVKEIKNKTNKEVVCDFKVADIPATNEKIAKTTLKYAD
AIICQGFVGKDSVMAIQKVAEEYGNKGAPKKVIMVTEMSHLSAVEFLQPVADDLAKMAKELSVDGVVAPSTRPERLKEIK
EIVGDIPIISPGVGAQGGDLDKVLEILGDNDYVIVGRGIYEHNNPKESAKHYKKLISKN
>Mature_219_residues
MKLMLALDVMSKNEALKIAEETKDFVDIIKIGYPLVLSTGIEIVKEIKNKTNKEVVCDFKVADIPATNEKIAKTTLKYAD
AIICQGFVGKDSVMAIQKVAEEYGNKGAPKKVIMVTEMSHLSAVEFLQPVADDLAKMAKELSVDGVVAPSTRPERLKEIK
EIVGDIPIISPGVGAQGGDLDKVLEILGDNDYVIVGRGIYEHNNPKESAKHYKKLISKN

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23939; Mature: 23939

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMLALDVMSKNEALKIAEETKDFVDIIKIGYPLVLSTGIEIVKEIKNKTNKEVVCDFK
CCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
VADIPATNEKIAKTTLKYADAIICQGFVGKDSVMAIQKVAEEYGNKGAPKKVIMVTEMSH
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECHHH
LSAVEFLQPVADDLAKMAKELSVDGVVAPSTRPERLKEIKEIVGDIPIISPGVGAQGGDL
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCH
DKVLEILGDNDYVIVGRGIYEHNNPKESAKHYKKLISKN
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLMLALDVMSKNEALKIAEETKDFVDIIKIGYPLVLSTGIEIVKEIKNKTNKEVVCDFK
CCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
VADIPATNEKIAKTTLKYADAIICQGFVGKDSVMAIQKVAEEYGNKGAPKKVIMVTEMSH
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECHHH
LSAVEFLQPVADDLAKMAKELSVDGVVAPSTRPERLKEIKEIVGDIPIISPGVGAQGGDL
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCH
DKVLEILGDNDYVIVGRGIYEHNNPKESAKHYKKLISKN
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]