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The map label for this gene is manB [H]

Identifier: 150400471

GI number: 150400471

Start: 34946

End: 36265

Strand: Reverse

Name: manB [H]

Synonym: Maeo_0032

Alternate gene names: 150400471

Gene position: 36265-34946 (Counterclockwise)

Preceding gene: 150400474

Following gene: 150400470

Centisome position: 2.31

GC content: 30.45

Gene sequence:

>1320_bases
ATGACAGTATTTAAGGCGTATGATATTAGGGGAGTATATCAAGAACAAATTGACGAAAAATTTGCCTATTCATTGGGGAA
ATCGATCGGAAAACGATACAATACCGTATTGGTTGGAAATGATGTAAGAATTGGCTCAAAGGAATTAGTAAAGCCATTTA
TTTATGGACTAATGGAGGAGGGGGTAAAGGTATCCTATTGTGGTACAATATCCACACCAACAATATATTTTGGAACAAAA
GATAATTATGATTTAGGAGTAATATTAACGGCATCACACAACCCTGCAAAATACACAGGATTTAAAATGTGTGATAAAAA
TGTAATACCAATATCCCCAACAGAAGAATTAATAAAAATATTTAATGAATATGAATTAACAGAAGAAACAAAAGAAAAAA
TTAAAAAAATGGATTTAAAAGATATTGTCGTAGATATAAAATCTAAATATATGGACTTCTTTTTAAATAGATGCAATACC
AGCAACAAAAAAATAGCCGTAGATTTTGCAAATGGTAGCACAGCAATAGCTGAAAAAGAAGTATTATCTAAATTATTAAT
AAACGGCATATTAATAAATGATTTCCCAGATGGAACATTTCCCGCCCATGAACCCGACACACTAAAAAAAGAATGCCTAA
TGGACATAATAAACACAGTTAAACATAACAACTGTGATATGGGGGTTATTTTCGATGGAGATGGAGATAGAATTGGAATA
ATTGACGAAAAAGGGGAAGTTTTACAGGGGGACATTTTAACGCTCCTTATAGCTATGGAGCTCCTAAAAGAAAAAAATGA
AAAATTAAAAATAGTTTATGATTTAAGATGTAGTAAAATAGTTGAAGAAGTAATTAATGAATATGGGGGAGCTCCCTTAA
AAACCAGGGTGGGTCACTATTTTATAAAAAAACTTATGCATGAAGTAGATGCAGAATTTGCAGGGGAACTGTCAAATCAT
TTCTATTTTAAAGAAGTTGGATATGTTGAAAGTCCATTGTTGGCACTAAATTATATATTGTCTGCTATGGAGGATATGGG
AAAAACACTTTCTGAACTATCAAAGGAATATAAAAAATACTTCCACAGCGGAGAGATAAACTTTAAAGTAAAAGACCAGC
AAGAAATATTAAATAAAATTGAAAATAAATATAAAAATTGTAAAATTGAAAAAATAGACGGATTATCTATATATTGCGAT
AACTGGTGGTTCAATGTTAGGTTATCCAATACAGAGCCACTTTTAAGGTTAAATTTAGAAGCAGATAGTAAAGAGCTCAT
GAATGAAAAAATTGAAGAAGTTAAAGGAATTATTGAATAG

Upstream 100 bases:

>100_bases
TCAAAATACCTTATAGTATATAATTAATGTGTGCCTACTTTTAATATACACTAATTATTAATTTATTTTTATTAAAAACG
AGAATATGAGGTAATAGAAT

Downstream 100 bases:

>100_bases
TTGAATAGATAATCATAAATATTCTATATATTTAACAGTTTTAATCTTCATCGAACCAAAGTATGCTATTAAATTTGATT
ATATTAAGTCTATAACCTAC

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTVFKAYDIRGVYQEQIDEKFAYSLGKSIGKRYNTVLVGNDVRIGSKELVKPFIYGLMEEGVKVSYCGTISTPTIYFGTK
DNYDLGVILTASHNPAKYTGFKMCDKNVIPISPTEELIKIFNEYELTEETKEKIKKMDLKDIVVDIKSKYMDFFLNRCNT
SNKKIAVDFANGSTAIAEKEVLSKLLINGILINDFPDGTFPAHEPDTLKKECLMDIINTVKHNNCDMGVIFDGDGDRIGI
IDEKGEVLQGDILTLLIAMELLKEKNEKLKIVYDLRCSKIVEEVINEYGGAPLKTRVGHYFIKKLMHEVDAEFAGELSNH
FYFKEVGYVESPLLALNYILSAMEDMGKTLSELSKEYKKYFHSGEINFKVKDQQEILNKIENKYKNCKIEKIDGLSIYCD
NWWFNVRLSNTEPLLRLNLEADSKELMNEKIEEVKGIIE

Sequences:

>Translated_439_residues
MTVFKAYDIRGVYQEQIDEKFAYSLGKSIGKRYNTVLVGNDVRIGSKELVKPFIYGLMEEGVKVSYCGTISTPTIYFGTK
DNYDLGVILTASHNPAKYTGFKMCDKNVIPISPTEELIKIFNEYELTEETKEKIKKMDLKDIVVDIKSKYMDFFLNRCNT
SNKKIAVDFANGSTAIAEKEVLSKLLINGILINDFPDGTFPAHEPDTLKKECLMDIINTVKHNNCDMGVIFDGDGDRIGI
IDEKGEVLQGDILTLLIAMELLKEKNEKLKIVYDLRCSKIVEEVINEYGGAPLKTRVGHYFIKKLMHEVDAEFAGELSNH
FYFKEVGYVESPLLALNYILSAMEDMGKTLSELSKEYKKYFHSGEINFKVKDQQEILNKIENKYKNCKIEKIDGLSIYCD
NWWFNVRLSNTEPLLRLNLEADSKELMNEKIEEVKGIIE
>Mature_438_residues
TVFKAYDIRGVYQEQIDEKFAYSLGKSIGKRYNTVLVGNDVRIGSKELVKPFIYGLMEEGVKVSYCGTISTPTIYFGTKD
NYDLGVILTASHNPAKYTGFKMCDKNVIPISPTEELIKIFNEYELTEETKEKIKKMDLKDIVVDIKSKYMDFFLNRCNTS
NKKIAVDFANGSTAIAEKEVLSKLLINGILINDFPDGTFPAHEPDTLKKECLMDIINTVKHNNCDMGVIFDGDGDRIGII
DEKGEVLQGDILTLLIAMELLKEKNEKLKIVYDLRCSKIVEEVINEYGGAPLKTRVGHYFIKKLMHEVDAEFAGELSNHF
YFKEVGYVESPLLALNYILSAMEDMGKTLSELSKEYKKYFHSGEINFKVKDQQEILNKIENKYKNCKIEKIDGLSIYCDN
WWFNVRLSNTEPLLRLNLEADSKELMNEKIEEVKGIIE

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=34.2465753424658, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1789566, Length=439, Percent_Identity=25.7403189066059, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 50178; Mature: 50046

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFKAYDIRGVYQEQIDEKFAYSLGKSIGKRYNTVLVGNDVRIGSKELVKPFIYGLMEE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHC
GVKVSYCGTISTPTIYFGTKDNYDLGVILTASHNPAKYTGFKMCDKNVIPISPTEELIKI
CCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHH
FNEYELTEETKEKIKKMDLKDIVVDIKSKYMDFFLNRCNTSNKKIAVDFANGSTAIAEKE
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
VLSKLLINGILINDFPDGTFPAHEPDTLKKECLMDIINTVKHNNCDMGVIFDGDGDRIGI
HHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
IDEKGEVLQGDILTLLIAMELLKEKNEKLKIVYDLRCSKIVEEVINEYGGAPLKTRVGHY
ECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHH
FIKKLMHEVDAEFAGELSNHFYFKEVGYVESPLLALNYILSAMEDMGKTLSELSKEYKKY
HHHHHHHHHCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSGEINFKVKDQQEILNKIENKYKNCKIEKIDGLSIYCDNWWFNVRLSNTEPLLRLNLE
HHCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCEEEEEECEEEEEEECCCCCEEEEECC
ADSKELMNEKIEEVKGIIE
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVFKAYDIRGVYQEQIDEKFAYSLGKSIGKRYNTVLVGNDVRIGSKELVKPFIYGLMEE
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHC
GVKVSYCGTISTPTIYFGTKDNYDLGVILTASHNPAKYTGFKMCDKNVIPISPTEELIKI
CCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHH
FNEYELTEETKEKIKKMDLKDIVVDIKSKYMDFFLNRCNTSNKKIAVDFANGSTAIAEKE
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
VLSKLLINGILINDFPDGTFPAHEPDTLKKECLMDIINTVKHNNCDMGVIFDGDGDRIGI
HHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
IDEKGEVLQGDILTLLIAMELLKEKNEKLKIVYDLRCSKIVEEVINEYGGAPLKTRVGHY
ECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHH
FIKKLMHEVDAEFAGELSNHFYFKEVGYVESPLLALNYILSAMEDMGKTLSELSKEYKKY
HHHHHHHHHCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSGEINFKVKDQQEILNKIENKYKNCKIEKIDGLSIYCDNWWFNVRLSNTEPLLRLNLE
HHCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCEEEEEECEEEEEEECCCCCEEEEECC
ADSKELMNEKIEEVKGIIE
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]