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The map label for this gene is arsC [H]

Identifier: 150400422

GI number: 150400422

Start: 1703494

End: 1703901

Strand: Reverse

Name: arsC [H]

Synonym: Mevan_1685

Alternate gene names: 150400422

Gene position: 1703901-1703494 (Counterclockwise)

Preceding gene: 150400423

Following gene: 150400421

Centisome position: 99.06

GC content: 28.43

Gene sequence:

>408_bases
TTGGATATTCCATTAAAATTGAAAAGTGAGAAAATAGCTTTTGTTTGCATCCATAATAAAAGGAGAAGCGTTATGGCTGA
ATCTTTTGCTAAAAGTTTAGGATTAAATGCATACAGTGCAGGTCTTGAAAAAACAGAACAGTTTGACGAAAAAGTAGTAA
CTGTTATGGAAGAATTAGGGTTAACGATTAAAAAAAAGCCGGAAACTATTTTGGAACTTCTTAAAAAAATTGAAAATATC
GATATTTTAGTTACCCTTGGCTGTATTGATTCTTGTCCAATCGTTAATGCAAAAAAACATATTTTATGGAATATTGAAGA
TCCTTCAGGAAAAGAAATTGAAGTCTATCGAAAAATTAGGGATGAAATAAAAATAAAAGTTGAAGAACTTTTAAAATTAG
AAGTATAA

Upstream 100 bases:

>100_bases
AAAATAAATCAATATATACCAATATATATTGATATATCGAAAACTATAAATATAGTTTAAAATATATTGATAGTTATTAA
TTAACCTTTTTGGTGAAAAC

Downstream 100 bases:

>100_bases
ATAATAAAAAATGTGTTTAGCTAGAAAAAGAAGTATAAATAATAAAAAATGTGTTTAGCTAGAAAAATAACAATAATAAA
ATATTATAGATTATAAAAAA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MDIPLKLKSEKIAFVCIHNKRRSVMAESFAKSLGLNAYSAGLEKTEQFDEKVVTVMEELGLTIKKKPETILELLKKIENI
DILVTLGCIDSCPIVNAKKHILWNIEDPSGKEIEVYRKIRDEIKIKVEELLKLEV

Sequences:

>Translated_135_residues
MDIPLKLKSEKIAFVCIHNKRRSVMAESFAKSLGLNAYSAGLEKTEQFDEKVVTVMEELGLTIKKKPETILELLKKIENI
DILVTLGCIDSCPIVNAKKHILWNIEDPSGKEIEVYRKIRDEIKIKVEELLKLEV
>Mature_135_residues
MDIPLKLKSEKIAFVCIHNKRRSVMAESFAKSLGLNAYSAGLEKTEQFDEKVVTVMEELGLTIKKKPETILELLKKIENI
DILVTLGCIDSCPIVNAKKHILWNIEDPSGKEIEVYRKIRDEIKIKVEELLKLEV

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15422; Mature: 15422

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPLKLKSEKIAFVCIHNKRRSVMAESFAKSLGLNAYSAGLEKTEQFDEKVVTVMEELG
CCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
LTIKKKPETILELLKKIENIDILVTLGCIDSCPIVNAKKHILWNIEDPSGKEIEVYRKIR
CEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
DEIKIKVEELLKLEV
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIPLKLKSEKIAFVCIHNKRRSVMAESFAKSLGLNAYSAGLEKTEQFDEKVVTVMEELG
CCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
LTIKKKPETILELLKKIENIDILVTLGCIDSCPIVNAKKHILWNIEDPSGKEIEVYRKIR
CEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
DEIKIKVEELLKLEV
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA