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The map label for this gene is yrhP [H]

Identifier: 150400348

GI number: 150400348

Start: 1629575

End: 1630198

Strand: Reverse

Name: yrhP [H]

Synonym: Mevan_1611

Alternate gene names: 150400348

Gene position: 1630198-1629575 (Counterclockwise)

Preceding gene: 150400351

Following gene: 150400345

Centisome position: 94.78

GC content: 28.69

Gene sequence:

>624_bases
TTGATAGAATATTCAAACTTATTTTATTTTATAAGTACATCAATTGTGTTGACCCTTTTACCCGGCCCTGACATTTTGTT
TGTAACCGTTCAAAGCATTTCAAATGGAAAAAAAGCAGGTATTTTAACTGCATTTGGACTATGTACGGGATTAATTATGC
ATACTATTGCTGCATCAGTTGGAATTTCAGCAATAATATATAATTCTGCACTTGGATTTAGTTTAGTTAAGTACGTTGGA
GCAGCATACTTAATTTACCTTTCAATTAATGCACTTTTTGAAAAAAATGGTTCTAATTTTGAAAAAACAGTAGTTAAAGA
GCCAGTAAATTTATATAGAAAAGGAATTTTCATGAATTTATTAAACCCAAAAGTTTCACTTTTCTTTTTAGCATTCCTCC
CGCAGTTTGTAAATTCTGATTATGGCAATATACCCATTCAAATGATAATATTGGGAATTATTTTTACGATTCAAGCAATT
TTAATTTTTTCAGCCGTTTCAATTCTTTCAAATGCTGTTAGTTTAAAAGTATTTGAAAATAAAAAATTCCAAAAATATGT
CTGCCCATTAAAAGCAAGCGTTTTTGGAATATTGGGAATTAAATTAGCATTTTTTGAACGGTAA

Upstream 100 bases:

>100_bases
TGTTCATACGGTAAAATCTTTTAGCGTTAAATTTTTTGTTTAATTTACGTTTAAAGCTAATTAAATTTAAAATTAAAGAA
TATGACGTTTGGGTGAAATT

Downstream 100 bases:

>100_bases
TATAATAGCGATATTATTGTAAAAATAAAACAATATTATTGTAAATATCGTAAAAATAAAAATTAATTTAAAAATAAAGA
ATATATTTCAAACATAAGTT

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIEYSNLFYFISTSIVLTLLPGPDILFVTVQSISNGKKAGILTAFGLCTGLIMHTIAASVGISAIIYNSALGFSLVKYVG
AAYLIYLSINALFEKNGSNFEKTVVKEPVNLYRKGIFMNLLNPKVSLFFLAFLPQFVNSDYGNIPIQMIILGIIFTIQAI
LIFSAVSILSNAVSLKVFENKKFQKYVCPLKASVFGILGIKLAFFER

Sequences:

>Translated_207_residues
MIEYSNLFYFISTSIVLTLLPGPDILFVTVQSISNGKKAGILTAFGLCTGLIMHTIAASVGISAIIYNSALGFSLVKYVG
AAYLIYLSINALFEKNGSNFEKTVVKEPVNLYRKGIFMNLLNPKVSLFFLAFLPQFVNSDYGNIPIQMIILGIIFTIQAI
LIFSAVSILSNAVSLKVFENKKFQKYVCPLKASVFGILGIKLAFFER
>Mature_207_residues
MIEYSNLFYFISTSIVLTLLPGPDILFVTVQSISNGKKAGILTAFGLCTGLIMHTIAASVGISAIIYNSALGFSLVKYVG
AAYLIYLSINALFEKNGSNFEKTVVKEPVNLYRKGIFMNLLNPKVSLFFLAFLPQFVNSDYGNIPIQMIILGIIFTIQAI
LIFSAVSILSNAVSLKVFENKKFQKYVCPLKASVFGILGIKLAFFER

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=197, Percent_Identity=27.9187817258883, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788099, Length=187, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786522, Length=191, Percent_Identity=23.0366492146597, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22779; Mature: 22779

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYSNLFYFISTSIVLTLLPGPDILFVTVQSISNGKKAGILTAFGLCTGLIMHTIAASV
CCEEHHHHHHEEHHHEEEECCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GISAIIYNSALGFSLVKYVGAAYLIYLSINALFEKNGSNFEKTVVKEPVNLYRKGIFMNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LNPKVSLFFLAFLPQFVNSDYGNIPIQMIILGIIFTIQAILIFSAVSILSNAVSLKVFEN
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
KKFQKYVCPLKASVFGILGIKLAFFER
CCHHHHHCCHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MIEYSNLFYFISTSIVLTLLPGPDILFVTVQSISNGKKAGILTAFGLCTGLIMHTIAASV
CCEEHHHHHHEEHHHEEEECCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GISAIIYNSALGFSLVKYVGAAYLIYLSINALFEKNGSNFEKTVVKEPVNLYRKGIFMNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LNPKVSLFFLAFLPQFVNSDYGNIPIQMIILGIIFTIQAILIFSAVSILSNAVSLKVFEN
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
KKFQKYVCPLKASVFGILGIKLAFFER
CCHHHHHCCHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]