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The map label for this gene is xseA [H]

Identifier: 150400340

GI number: 150400340

Start: 1621681

End: 1622913

Strand: Reverse

Name: xseA [H]

Synonym: Mevan_1603

Alternate gene names: 150400340

Gene position: 1622913-1621681 (Counterclockwise)

Preceding gene: 150400341

Following gene: 150400339

Centisome position: 94.35

GC content: 29.44

Gene sequence:

>1233_bases
ATGCTCCAACTAACATTAGAAAGTGCTTTTTCAAACACATTGTCTGTTTCAGAATTAAATTTATACGTGAAAAACACTTT
AGAAAATGATTTAATATTAAAACGTGCTTCAATCAAAGGAGAAATTTCCAATTGCATACTACATCGGTCAGGACATATTT
ATTTTACACTAAAAGATGAAGAAGGCGCAATTGACTGCGTAATGTTTAAAGGGGATGCACGGCTCCTTAATTTTATTCCA
AAAGATGGAATAAAAGTAATAGTTACAGGAAAGGTTTCAATATATGCTAAAACTGGAAAGTACCAAGTTTACTGTAATTC
TATGGAAAAGGAGGGAATCGGCGAGTTATACATAAAATTTGAAAAATTAAAGGAAAAACTTGAAAAAGAAGGACTTTTTG
ATGAATTAAAAAAGAAAAAAATTCCAAGATATGCAAAAAATATTGGAATAATAACATCACCAACCGGAGCTGCATTAACG
GATATTATAAAGGTTACAAGACTTAGAAATCGGTCAGTTAATTTATTGATATATCCTGCATCAGTTCAGGGTGAAAATGC
GCCTTCTGAGATAATAAACGGAATTTCCAAGCTTAATAATCATAAAGATATCGATTTAATAATTCTAGCACGAGGAGGGG
GTGCAATTGAAGATTTATGGTGTTTTAACGATGAATCACTTGCAAGAGCCATTTTTAAATCAGAAAAACCAATAGTTACA
GGAATAGGGCATGAAATAGACTTTACAATAGCAGATTTTGTAAGCGATTTAAGGGCAGCAACTCCTTCAAATGCTGCTGA
AATTTCAGTATTTAATGAATTTGAATTAATTTCAAAATTGAAAAATCTTGAAAAAAACCTAAGTACGAAAATTTTAACTG
ACATTTCAAAGAAAGCTTATGAAGTAGATTTTTTGTATTCAAAGTTTGAAAAAAACAGCCCTAACTCAAAAATTGAAAAA
CAAAAAGCAATTCTTGAACGTTACAATGCATTAATAACTCACGAAATTAAAAATAAATTTGCATACGAGTTAAAGCGTTT
TGAAAAGGCCCATTCTCTTTTAAATGCGTATAATCCATTAAATGTACTTAATAAAGGGTACACGATAATTCAAAATCCTG
ATGGAAGAATAATAAGCTCTAAAGAATTATTAAAGTCAAAAAAAGAATTAAAAATAATATTTAAAGATGGAATTGTAGAT
GTAAATATTACTTTAAAAGATAGGGTGAGATAA

Upstream 100 bases:

>100_bases
ATAAATTAATACATTTTTAATAGTAATACTCCTTGTGTTTATTATTTAAATAGTTAAAAAAGAAAAAATTAAAACCAAGG
TAAATGTCACGGTAATAATT

Downstream 100 bases:

>100_bases
TGGAAAAATACGAAGATTTGATCGAAAACCTCGAAAATATTGTAAATTTAATGGAAAATGAAGAATTATCTCTTGAAGAA
GCAATGAAAAACTATGAAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLQLTLESAFSNTLSVSELNLYVKNTLENDLILKRASIKGEISNCILHRSGHIYFTLKDEEGAIDCVMFKGDARLLNFIP
KDGIKVIVTGKVSIYAKTGKYQVYCNSMEKEGIGELYIKFEKLKEKLEKEGLFDELKKKKIPRYAKNIGIITSPTGAALT
DIIKVTRLRNRSVNLLIYPASVQGENAPSEIINGISKLNNHKDIDLIILARGGGAIEDLWCFNDESLARAIFKSEKPIVT
GIGHEIDFTIADFVSDLRAATPSNAAEISVFNEFELISKLKNLEKNLSTKILTDISKKAYEVDFLYSKFEKNSPNSKIEK
QKAILERYNALITHEIKNKFAYELKRFEKAHSLLNAYNPLNVLNKGYTIIQNPDGRIISSKELLKSKKELKIIFKDGIVD
VNITLKDRVR

Sequences:

>Translated_410_residues
MLQLTLESAFSNTLSVSELNLYVKNTLENDLILKRASIKGEISNCILHRSGHIYFTLKDEEGAIDCVMFKGDARLLNFIP
KDGIKVIVTGKVSIYAKTGKYQVYCNSMEKEGIGELYIKFEKLKEKLEKEGLFDELKKKKIPRYAKNIGIITSPTGAALT
DIIKVTRLRNRSVNLLIYPASVQGENAPSEIINGISKLNNHKDIDLIILARGGGAIEDLWCFNDESLARAIFKSEKPIVT
GIGHEIDFTIADFVSDLRAATPSNAAEISVFNEFELISKLKNLEKNLSTKILTDISKKAYEVDFLYSKFEKNSPNSKIEK
QKAILERYNALITHEIKNKFAYELKRFEKAHSLLNAYNPLNVLNKGYTIIQNPDGRIISSKELLKSKKELKIIFKDGIVD
VNITLKDRVR
>Mature_410_residues
MLQLTLESAFSNTLSVSELNLYVKNTLENDLILKRASIKGEISNCILHRSGHIYFTLKDEEGAIDCVMFKGDARLLNFIP
KDGIKVIVTGKVSIYAKTGKYQVYCNSMEKEGIGELYIKFEKLKEKLEKEGLFDELKKKKIPRYAKNIGIITSPTGAALT
DIIKVTRLRNRSVNLLIYPASVQGENAPSEIINGISKLNNHKDIDLIILARGGGAIEDLWCFNDESLARAIFKSEKPIVT
GIGHEIDFTIADFVSDLRAATPSNAAEISVFNEFELISKLKNLEKNLSTKILTDISKKAYEVDFLYSKFEKNSPNSKIEK
QKAILERYNALITHEIKNKFAYELKRFEKAHSLLNAYNPLNVLNKGYTIIQNPDGRIISSKELLKSKKELKIIFKDGIVD
VNITLKDRVR

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=443, Percent_Identity=34.5372460496614, Blast_Score=293, Evalue=9e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 46299; Mature: 46299

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLTLESAFSNTLSVSELNLYVKNTLENDLILKRASIKGEISNCILHRSGHIYFTLKDE
CEEEEEEHHHCCCEEEHHEEEEEECCCCCCCEEEEHHCCCCHHHHEEECCCEEEEEEECC
EGAIDCVMFKGDARLLNFIPKDGIKVIVTGKVSIYAKTGKYQVYCNSMEKEGIGELYIKF
CCCEEEEEEECCCCEECCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCCCCCHHHHHHH
EKLKEKLEKEGLFDELKKKKIPRYAKNIGIITSPTGAALTDIIKVTRLRNRSVNLLIYPA
HHHHHHHHHCCHHHHHHHHCCCHHHHHCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEEC
SVQGENAPSEIINGISKLNNHKDIDLIILARGGGAIEDLWCFNDESLARAIFKSEKPIVT
CCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHEEECCCHHHHHHHHCCCCCEEE
GIGHEIDFTIADFVSDLRAATPSNAAEISVFNEFELISKLKNLEKNLSTKILTDISKKAY
ECCCEEEEEHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
EVDFLYSKFEKNSPNSKIEKQKAILERYNALITHEIKNKFAYELKRFEKAHSLLNAYNPL
EHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NVLNKGYTIIQNPDGRIISSKELLKSKKELKIIFKDGIVDVNITLKDRVR
HHHCCCEEEEECCCCCEECCHHHHCCHHHEEEEEECCEEEEEEEECCCCC
>Mature Secondary Structure
MLQLTLESAFSNTLSVSELNLYVKNTLENDLILKRASIKGEISNCILHRSGHIYFTLKDE
CEEEEEEHHHCCCEEEHHEEEEEECCCCCCCEEEEHHCCCCHHHHEEECCCEEEEEEECC
EGAIDCVMFKGDARLLNFIPKDGIKVIVTGKVSIYAKTGKYQVYCNSMEKEGIGELYIKF
CCCEEEEEEECCCCEECCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCCCCCHHHHHHH
EKLKEKLEKEGLFDELKKKKIPRYAKNIGIITSPTGAALTDIIKVTRLRNRSVNLLIYPA
HHHHHHHHHCCHHHHHHHHCCCHHHHHCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEEC
SVQGENAPSEIINGISKLNNHKDIDLIILARGGGAIEDLWCFNDESLARAIFKSEKPIVT
CCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHEEECCCHHHHHHHHCCCCCEEE
GIGHEIDFTIADFVSDLRAATPSNAAEISVFNEFELISKLKNLEKNLSTKILTDISKKAY
ECCCEEEEEHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
EVDFLYSKFEKNSPNSKIEKQKAILERYNALITHEIKNKFAYELKRFEKAHSLLNAYNPL
EHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NVLNKGYTIIQNPDGRIISSKELLKSKKELKIIFKDGIVDVNITLKDRVR
HHHCCCEEEEECCCCCEECCHHHHCCHHHEEEEEECCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA