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The map label for this gene is wecB [H]

Identifier: 150400320

GI number: 150400320

Start: 1598313

End: 1599404

Strand: Reverse

Name: wecB [H]

Synonym: Mevan_1583

Alternate gene names: 150400320

Gene position: 1599404-1598313 (Counterclockwise)

Preceding gene: 150400321

Following gene: 150400319

Centisome position: 92.99

GC content: 29.21

Gene sequence:

>1092_bases
ATGTTAAAAATAGGGATAATCCTTGGAACTCGACCCGAGATAATTAAAATGTCCCCCTTAATTCGGGGACTACAAAATAA
AAATTCTTTTTTAATTCATACGAATCAACATTATTCTGAAAATATGGATAAAATCTTTTTTGAAGAATTAAATTTAAAAA
GACCGGATTATAATTTAAATATAGGGTCAAGTAGTCATGGAAATCAGACCGGAAGGATGTTAGTTGAAATTGAAAAGGTT
TTACTAAACGAAAAACCCGATATAGTACTTGTCCAAGGTGACACAAACACGGTTTTAGCGGGAGCCCTTGCAGCTTCTAA
ATTAAATATAAAAATAGCACATATTGAAGCAGGACTTAGAAGTTTTGATAGAAAAATGCCTGAAGAGACTAATCGTGTTT
TGACAGACCATATTTCACACTATCTATTTGCACCAACTGAAATTGCAAAAAAAAATATTTTAAGAGAAGGAATACTTGAA
AAAAATATATTTGTTGTTGGAAATACCATTGTTGATGCAACTGTTCAAAACTTAAAAATTGCGGAACAAAATAAAGATAT
TTGCACTTTTTTATCAAATTTAACAGGAAATAATGAATATTTTTTATTAACATTACATCGGGCAGAAAATACAGATAGTG
TTGAAAATCTATCAAAACTTGTATTTGCAATAACTCAAATCGTTAAAAAATATCAAAAACAAATTATTTTTCCAGTGCAT
CCTAGGACGAAAAAAAAATTAATTGAGTTTGGACTTTTTAACGATTTATCAAAAAATAACTTGGTAAAAGTGATTGAACC
TATAGGATACCTTGAATTTTTAATGCTTGAAAAAAATGCTCGTTTAATAATTACAGATAGTGGTGGCGTTCAAGAAGAAG
CTTGTATTTTAAATGTTCCCTGTGTAACTTTAAGGGAAAATACTGAACGGCCAGAAACTATTTTGGTAAACTCAAACATC
CTTTCAGGATGTGAACCTGAAAAAATCCTTAATTCCATTGATTTTATGCTAAATAACAATAATACTTGGGAAAATCCGTT
TGGAAAAGGGAATTCTGGAGAAAAAATTATTGAGATACTTTTAAATAAATAA

Upstream 100 bases:

>100_bases
AATAAGCTCATAATTGACACTAAGAATATATTAAATCATAACCTTTGGAAAAAAGCAGGATTTAAAATAAAACTGCTCGG
TAATGGGGCTTGGTGACTAA

Downstream 100 bases:

>100_bases
AAATATAATAATGATTTGCCCATATGGGTAAATTATTTTATATATTATGTTAATTTACATATTGATGAAATTTAATAAAG
CCAGATGGTGAAAAGCATGT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKIGIILGTRPEIIKMSPLIRGLQNKNSFLIHTNQHYSENMDKIFFEELNLKRPDYNLNIGSSSHGNQTGRMLVEIEKV
LLNEKPDIVLVQGDTNTVLAGALAASKLNIKIAHIEAGLRSFDRKMPEETNRVLTDHISHYLFAPTEIAKKNILREGILE
KNIFVVGNTIVDATVQNLKIAEQNKDICTFLSNLTGNNEYFLLTLHRAENTDSVENLSKLVFAITQIVKKYQKQIIFPVH
PRTKKKLIEFGLFNDLSKNNLVKVIEPIGYLEFLMLEKNARLIITDSGGVQEEACILNVPCVTLRENTERPETILVNSNI
LSGCEPEKILNSIDFMLNNNNTWENPFGKGNSGEKIIEILLNK

Sequences:

>Translated_363_residues
MLKIGIILGTRPEIIKMSPLIRGLQNKNSFLIHTNQHYSENMDKIFFEELNLKRPDYNLNIGSSSHGNQTGRMLVEIEKV
LLNEKPDIVLVQGDTNTVLAGALAASKLNIKIAHIEAGLRSFDRKMPEETNRVLTDHISHYLFAPTEIAKKNILREGILE
KNIFVVGNTIVDATVQNLKIAEQNKDICTFLSNLTGNNEYFLLTLHRAENTDSVENLSKLVFAITQIVKKYQKQIIFPVH
PRTKKKLIEFGLFNDLSKNNLVKVIEPIGYLEFLMLEKNARLIITDSGGVQEEACILNVPCVTLRENTERPETILVNSNI
LSGCEPEKILNSIDFMLNNNNTWENPFGKGNSGEKIIEILLNK
>Mature_363_residues
MLKIGIILGTRPEIIKMSPLIRGLQNKNSFLIHTNQHYSENMDKIFFEELNLKRPDYNLNIGSSSHGNQTGRMLVEIEKV
LLNEKPDIVLVQGDTNTVLAGALAASKLNIKIAHIEAGLRSFDRKMPEETNRVLTDHISHYLFAPTEIAKKNILREGILE
KNIFVVGNTIVDATVQNLKIAEQNKDICTFLSNLTGNNEYFLLTLHRAENTDSVENLSKLVFAITQIVKKYQKQIIFPVH
PRTKKKLIEFGLFNDLSKNNLVKVIEPIGYLEFLMLEKNARLIITDSGGVQEEACILNVPCVTLRENTERPETILVNSNI
LSGCEPEKILNSIDFMLNNNNTWENPFGKGNSGEKIIEILLNK

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=384, Percent_Identity=35.6770833333333, Blast_Score=197, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41032; Mature: 41032

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGIILGTRPEIIKMSPLIRGLQNKNSFLIHTNQHYSENMDKIFFEELNLKRPDYNLN
CEEEEEEECCCCCEEEHHHHHHHHCCCCCEEEECCCHHHCCHHHHHHHHHCCCCCCCEEE
IGSSSHGNQTGRMLVEIEKVLLNEKPDIVLVQGDTNTVLAGALAASKLNIKIAHIEAGLR
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHEEEEEEEEEEEEHHHHH
SFDRKMPEETNRVLTDHISHYLFAPTEIAKKNILREGILEKNIFVVGNTIVDATVQNLKI
HHHHHCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCEE
AEQNKDICTFLSNLTGNNEYFLLTLHRAENTDSVENLSKLVFAITQIVKKYQKQIIFPVH
ECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECC
PRTKKKLIEFGLFNDLSKNNLVKVIEPIGYLEFLMLEKNARLIITDSGGVQEEACILNVP
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCHHEEEEEECCCEEEEECCCCCCCCEEEEECC
CVTLRENTERPETILVNSNILSGCEPEKILNSIDFMLNNNNTWENPFGKGNSGEKIIEIL
EEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHE
LNK
ECC
>Mature Secondary Structure
MLKIGIILGTRPEIIKMSPLIRGLQNKNSFLIHTNQHYSENMDKIFFEELNLKRPDYNLN
CEEEEEEECCCCCEEEHHHHHHHHCCCCCEEEECCCHHHCCHHHHHHHHHCCCCCCCEEE
IGSSSHGNQTGRMLVEIEKVLLNEKPDIVLVQGDTNTVLAGALAASKLNIKIAHIEAGLR
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHEEEEEEEEEEEEHHHHH
SFDRKMPEETNRVLTDHISHYLFAPTEIAKKNILREGILEKNIFVVGNTIVDATVQNLKI
HHHHHCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCEE
AEQNKDICTFLSNLTGNNEYFLLTLHRAENTDSVENLSKLVFAITQIVKKYQKQIIFPVH
ECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECC
PRTKKKLIEFGLFNDLSKNNLVKVIEPIGYLEFLMLEKNARLIITDSGGVQEEACILNVP
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCHHEEEEEECCCEEEEECCCCCCCCEEEEECC
CVTLRENTERPETILVNSNILSGCEPEKILNSIDFMLNNNNTWENPFGKGNSGEKIIEIL
EEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHE
LNK
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA