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The map label for this gene is ilvC [H]

Identifier: 150400276

GI number: 150400276

Start: 1552125

End: 1553117

Strand: Reverse

Name: ilvC [H]

Synonym: Mevan_1538

Alternate gene names: 150400276

Gene position: 1553117-1552125 (Counterclockwise)

Preceding gene: 150400279

Following gene: 150400275

Centisome position: 90.29

GC content: 36.76

Gene sequence:

>993_bases
ATGAAGGTATTCTACGATGCAGACATAAAATTAGACGCTTTAAAAAGTAAAACAATTGCAGTTATTGGTTACGGAAGTCA
GGGTAGAGCCCAGTCTTTAAACATGAAAGACAGCGGTTTAAACGTTGTAGTTGGTTTAAGGAAAAACGGTGCTTCATGGG
AAAACGCTAAAAACGATGGTCATGAAGTATTAACGATTGAAGAAGCTTCAAAAAAAGCAGACATAATTCATATATTAATC
CCTGATGAATTACAGGCTGAAGTTTACGAAAGCCAGATAAAACCATACCTTACAGAAGGAAAAACATTAAGCTTCTCACA
CGGCTTTAATATCCATTATGGGTTTATTATTCCGCCAAAAGGAGTTAACGTGGTTTTAGTTGCACCAAAGTCACCCGGTA
AAATGGTTAGAAAAACATACGAAGAAGGATTTGGTGTTCCGGGATTAATCTGTATAGAAGTAGATGCTACAAATACTGCA
TTTGAGACTGTTTCAGCAATGGCAAAGGGGATCGGCCTCTCAAGAGCAGGCGTTATCCAGACAACATTTAGGGAGGAAAC
TGAAACCGATCTTTTTGGTGAACAGGCAGTATTGTGCGGCGGAGTTACTGAATTAATTAAAGCAGGATTTGAAACACTCG
TTGAAGCAGGATATTCACCTGAAATGGCGTATTTTGAAACATGCCACGAGTTAAAATTAATTGTTGACTTAATTTACCAA
AAAGGATTCAAAAACATGTGGCATGATGTAAGTAATACTGCAGAATATGGTGGACTTACAAGAAGAAGCAGAATCGTTAC
TGCTGACTCAAAAGCTGCGATGAAAGAAATTTTAAAAGAGATTCAAGATGGAAGATTTACAAAAGAATTTGTTCTTGAAA
ATCAAGCTAAAATGGCACATTTAAAAGCAATGAGGAGACTTGAAGGCGAATTGCAAATTGAAGAAGTCGGTTCAAAGTTA
AGAAAAATGTGTGGTCTTGAAAAAGACGAATAA

Upstream 100 bases:

>100_bases
ATCGATAAATTTATAGATCTAAATAAGAATATATGTGGCATATATGTTAACATTATATATGATTATGTGATAATGGATTG
TGAGATTAGAGGTGAAGACT

Downstream 100 bases:

>100_bases
TTTTTATTTTTTATCTATTTATTTACTTTTTTAGGGGGATTTTTTTGAAAATTTTCGCAAAAATTGGTGAAAACTCTTTT
GAACTTGAATTTTCAAAAGA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKVFYDADIKLDALKSKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWENAKNDGHEVLTIEEASKKADIIHILI
PDELQAEVYESQIKPYLTEGKTLSFSHGFNIHYGFIIPPKGVNVVLVAPKSPGKMVRKTYEEGFGVPGLICIEVDATNTA
FETVSAMAKGIGLSRAGVIQTTFREETETDLFGEQAVLCGGVTELIKAGFETLVEAGYSPEMAYFETCHELKLIVDLIYQ
KGFKNMWHDVSNTAEYGGLTRRSRIVTADSKAAMKEILKEIQDGRFTKEFVLENQAKMAHLKAMRRLEGELQIEEVGSKL
RKMCGLEKDE

Sequences:

>Translated_330_residues
MKVFYDADIKLDALKSKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWENAKNDGHEVLTIEEASKKADIIHILI
PDELQAEVYESQIKPYLTEGKTLSFSHGFNIHYGFIIPPKGVNVVLVAPKSPGKMVRKTYEEGFGVPGLICIEVDATNTA
FETVSAMAKGIGLSRAGVIQTTFREETETDLFGEQAVLCGGVTELIKAGFETLVEAGYSPEMAYFETCHELKLIVDLIYQ
KGFKNMWHDVSNTAEYGGLTRRSRIVTADSKAAMKEILKEIQDGRFTKEFVLENQAKMAHLKAMRRLEGELQIEEVGSKL
RKMCGLEKDE
>Mature_330_residues
MKVFYDADIKLDALKSKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWENAKNDGHEVLTIEEASKKADIIHILI
PDELQAEVYESQIKPYLTEGKTLSFSHGFNIHYGFIIPPKGVNVVLVAPKSPGKMVRKTYEEGFGVPGLICIEVDATNTA
FETVSAMAKGIGLSRAGVIQTTFREETETDLFGEQAVLCGGVTELIKAGFETLVEAGYSPEMAYFETCHELKLIVDLIYQ
KGFKNMWHDVSNTAEYGGLTRRSRIVTADSKAAMKEILKEIQDGRFTKEFVLENQAKMAHLKAMRRLEGELQIEEVGSKL
RKMCGLEKDE

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=291, Percent_Identity=36.0824742268041, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323387, Length=323, Percent_Identity=37.1517027863777, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 36508; Mature: 36508

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFYDADIKLDALKSKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWENAKNDG
CEEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
HEVLTIEEASKKADIIHILIPDELQAEVYESQIKPYLTEGKTLSFSHGFNIHYGFIIPPK
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCEECCCCEEEEECCCEEEEEEEECCC
GVNVVLVAPKSPGKMVRKTYEEGFGVPGLICIEVDATNTAFETVSAMAKGIGLSRAGVIQ
CCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEE
TTFREETETDLFGEQAVLCGGVTELIKAGFETLVEAGYSPEMAYFETCHELKLIVDLIYQ
HHHHCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KGFKNMWHDVSNTAEYGGLTRRSRIVTADSKAAMKEILKEIQDGRFTKEFVLENQAKMAH
HHHHHHHHHHCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHH
LKAMRRLEGELQIEEVGSKLRKMCGLEKDE
HHHHHHHCCCEEHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKVFYDADIKLDALKSKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWENAKNDG
CEEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
HEVLTIEEASKKADIIHILIPDELQAEVYESQIKPYLTEGKTLSFSHGFNIHYGFIIPPK
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCEECCCCEEEEECCCEEEEEEEECCC
GVNVVLVAPKSPGKMVRKTYEEGFGVPGLICIEVDATNTAFETVSAMAKGIGLSRAGVIQ
CCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEE
TTFREETETDLFGEQAVLCGGVTELIKAGFETLVEAGYSPEMAYFETCHELKLIVDLIYQ
HHHHCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KGFKNMWHDVSNTAEYGGLTRRSRIVTADSKAAMKEILKEIQDGRFTKEFVLENQAKMAH
HHHHHHHHHHCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHH
LKAMRRLEGELQIEEVGSKLRKMCGLEKDE
HHHHHHHCCCEEHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA