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The map label for this gene is aroK

Identifier: 150400073

GI number: 150400073

Start: 1357235

End: 1358086

Strand: Reverse

Name: aroK

Synonym: Mevan_1331

Alternate gene names: 150400073

Gene position: 1358086-1357235 (Counterclockwise)

Preceding gene: 150400076

Following gene: 150400072

Centisome position: 78.96

GC content: 31.81

Gene sequence:

>852_bases
ATGAGATGCTCTGCAATTTCCCCCGGTTCTGGAACAATTATTAACGCAATTTCAACAGGCAAGGGTTCTGCATTTGGGAT
TGATTTAAAAATAAAAGCAAATGTAGAGTTGAAAAATGATGGAAAAAGTAAAATAAATGGAATTTTACTCGATAATCCAT
CTTTAAAGCCAAACTTGGTTGAAAGATGCGTTAAAAATGTTTTGGAGCATTTTGAAGTAGATTATTCTGCAAAAATTTCA
ACCAGTAGTGAACTTCCATTAAAATCTGGATTAAGTAGTAGTAGTGCAGCATCAAATGCAGCAGTTCTTGCGACATTTGG
GGCACTTGGCGAAAAAATAGATTCTGAGTTAATTTTAGACCTTGCAATAAAATCCTCTTTTGAAGAACAATTAACAATAA
CTGGGGCATATGACGATGCAACAGCATCATATTTTGGTGGAATTACCGTCTGTAATAATTTAGAAAGAAAAATACTGAAA
AAAGACGTTTTTAAAGAAGAATTAGACGTTATTATATTAATGCCAAATTTTAAAAAGAACCTGAATGTAAAGAGGATGAA
ATTAATAAGTGATTATGTTGAACTAGCATTTGAAAAGTGTATGAATGCAGATTATTATAAAGCATTATTTTTAAACGGTA
TTCTTTATTCTTCTGCACTAAATTTCCCATCATACATTTCCGTAGATGCCTTAGAAGCAGGTGCTGTTACTGCAGGCCTT
TCTGGAACTGGGCCTTCGTATATAGCACTATCTTATCAGGAAAATACTGAAAAAGTTAAGAATGCTTTTAAAAAATATGG
AACAGTGATTATTTCAAAACCTGATAATTTTGGTTCAAAAATAATTTACTAG

Upstream 100 bases:

>100_bases
TTGATTTTATATGTTAGTTTCGCTTATTAAATTTAAATTCTACTTTATTTTCTATTAGTTATATTGGTTATTATTTATTG
GATTATCCTTTGGTGACATT

Downstream 100 bases:

>100_bases
AGTAATTTAGTAATTTAATTTTAAAATTTTTAAAAATTTAAAAAAAGGTGAACGTTATGGTTGATAAAATATATGGAATA
GGCGTTGGGCCAGGAGATAC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRCSAISPGSGTIINAISTGKGSAFGIDLKIKANVELKNDGKSKINGILLDNPSLKPNLVERCVKNVLEHFEVDYSAKIS
TSSELPLKSGLSSSSAASNAAVLATFGALGEKIDSELILDLAIKSSFEEQLTITGAYDDATASYFGGITVCNNLERKILK
KDVFKEELDVIILMPNFKKNLNVKRMKLISDYVELAFEKCMNADYYKALFLNGILYSSALNFPSYISVDALEAGAVTAGL
SGTGPSYIALSYQENTEKVKNAFKKYGTVIISKPDNFGSKIIY

Sequences:

>Translated_283_residues
MRCSAISPGSGTIINAISTGKGSAFGIDLKIKANVELKNDGKSKINGILLDNPSLKPNLVERCVKNVLEHFEVDYSAKIS
TSSELPLKSGLSSSSAASNAAVLATFGALGEKIDSELILDLAIKSSFEEQLTITGAYDDATASYFGGITVCNNLERKILK
KDVFKEELDVIILMPNFKKNLNVKRMKLISDYVELAFEKCMNADYYKALFLNGILYSSALNFPSYISVDALEAGAVTAGL
SGTGPSYIALSYQENTEKVKNAFKKYGTVIISKPDNFGSKIIY
>Mature_283_residues
MRCSAISPGSGTIINAISTGKGSAFGIDLKIKANVELKNDGKSKINGILLDNPSLKPNLVERCVKNVLEHFEVDYSAKIS
TSSELPLKSGLSSSSAASNAAVLATFGALGEKIDSELILDLAIKSSFEEQLTITGAYDDATASYFGGITVCNNLERKILK
KDVFKEELDVIILMPNFKKNLNVKRMKLISDYVELAFEKCMNADYYKALFLNGILYSSALNFPSYISVDALEAGAVTAGL
SGTGPSYIALSYQENTEKVKNAFKKYGTVIISKPDNFGSKIIY

Specific function: Threonine biosynthesis from asparate; fourth step. [C]

COG id: COG1685

COG function: function code EH; Archaeal shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_METVS (A6URV6)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323840.1
- ProteinModelPortal:   A6URV6
- SMR:   A6URV6
- STRING:   A6URV6
- GeneID:   5325165
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_1331
- eggNOG:   arNOG05254
- HOGENOM:   HBG646614
- OMA:   AFDDACA
- ProtClustDB:   PRK01123
- GO:   GO:0005737
- HAMAP:   MF_00370
- InterPro:   IPR006204
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR010189
- Gene3D:   G3DSA:3.30.230.10
- PIRSF:   PIRSF005758
- TIGRFAMs:   TIGR01920

Pfam domain/function: PF00288 GHMP_kinases_N; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.1.71

Molecular weight: Translated: 30579; Mature: 30579

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCSAISPGSGTIINAISTGKGSAFGIDLKIKANVELKNDGKSKINGILLDNPSLKPNLV
CCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCCHHCEEEECCCCCCHHHH
ERCVKNVLEHFEVDYSAKISTSSELPLKSGLSSSSAASNAAVLATFGALGEKIDSELILD
HHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAIKSSFEEQLTITGAYDDATASYFGGITVCNNLERKILKKDVFKEELDVIILMPNFKKN
HHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
LNVKRMKLISDYVELAFEKCMNADYYKALFLNGILYSSALNFPSYISVDALEAGAVTAGL
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECC
SGTGPSYIALSYQENTEKVKNAFKKYGTVIISKPDNFGSKIIY
CCCCCCEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRCSAISPGSGTIINAISTGKGSAFGIDLKIKANVELKNDGKSKINGILLDNPSLKPNLV
CCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCCHHCEEEECCCCCCHHHH
ERCVKNVLEHFEVDYSAKISTSSELPLKSGLSSSSAASNAAVLATFGALGEKIDSELILD
HHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAIKSSFEEQLTITGAYDDATASYFGGITVCNNLERKILKKDVFKEELDVIILMPNFKKN
HHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
LNVKRMKLISDYVELAFEKCMNADYYKALFLNGILYSSALNFPSYISVDALEAGAVTAGL
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECC
SGTGPSYIALSYQENTEKVKNAFKKYGTVIISKPDNFGSKIIY
CCCCCCEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA