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The map label for this gene is kamA [H]

Identifier: 150399966

GI number: 150399966

Start: 1252902

End: 1254203

Strand: Reverse

Name: kamA [H]

Synonym: Mevan_1223

Alternate gene names: 150399966

Gene position: 1254203-1252902 (Counterclockwise)

Preceding gene: 150399967

Following gene: 150399965

Centisome position: 72.92

GC content: 32.49

Gene sequence:

>1302_bases
TTGAATAAAGTTGAAAATACAGTTGACTTAAAATTTTTAAAAAAATTTTCTAAAGATGTAACATATAATGATTGGAATGA
TTATAAATGGCAGATTTCTAATTCAATTAAATCTCTTGACATGCTTGAAAACGTACTTGAAATAAAATTTCCAGATAACG
AAAGAAAAGAAATTCAAAAGGCGATTGAAGTTTTCCCAATGTCAATAACTCCATATTATGCAAGTTTGATTGACATTAGT
AATTTAAAAAAAGACCCAATTTATAAACAGAGTGTAGCTTCTAAAAAAGAGCTAATAATGGAAGATTTTGAAATGGAAGA
CCCTTTAGCAGAGGATAAAGACTCTCCTGTCATAGGAATAACCCATAGATACCCAGACAGAGTTTTATTTTATGTAAATC
CAAACTGTGCAATGTATTGTAGGCACTGTACAAGAAAAAGGAAAGTTTCAGAAAGTGAAAGTAACCCATCAAAAGAAGAA
ATTCAAAAGGCGATTGATTATATAAAAGAACATCCGGAAGTTAGAGATGTTTTACTTTCTGGTGGAGACCCATTATTACT
TTCTGACGATTATTTAGACTGGATTCTTTCAGAAATAAGCAGTATTGAACATGTTGAACTTATAAGAATTGGTTCAAGAG
TTCCAGTGGTGCTCCCACAAAGAATAACTGACAATTTAGTCAATATATTAAAAAAATACCATCCAATATGGGTAAATACG
CATTTTAACCATGTTGTAGAAATTACAGATACCTCAGTAGAAGCTCTTGATAAACTTTCTAATGCAGGAATACCAATTGG
AAACCAGACTGTTTTGCTTTCAGGAGTAAATGATTGTCCATATGTTATGAGAAAATTAAATCAAAAGCTTGTTTCTTCAA
GAGTTAGGCCTTACTACCTTTACCAGTGCGACCTTTCTAAAGGAATATCCCATTTTAGGACTTCAATAAGTAAAGGTCTT
GAAATTATTGAAAGCTTAATTGGACATACAACTGGTTTTGCAGTTCCTAGATACGTTGTTGATGCACCGGGGGGCGGCGG
AAAAATTCCAGTTATGCCTAATTACGTGGTTTCGTGGGGTTCAGATAGGGTAATTCTAAGAAACTATGAAGGAGTAATTA
CAACGTATAAAGAACCTTCAAACTATGAAGGATGCAGTAAAAATTGTAATAAATGTAGTAGGCTATCTATTGATGACTTT
GAAATCAACCAGACTGGAATTGAAAAATTAATAACAAATGTGGATACCTCAATTTCACTCGTGCCATCCAATAATAAAAG
AATGTGTAGGAGGGAAAAGTAA

Upstream 100 bases:

>100_bases
TTTCGGTTTTTTAATTTTCTATTTAGGATACCCCTAAAGGTACTATCAAGGACGGGTTTTAATTTTTTAGTTTGAATATT
TAGATATATTAGGTGATATA

Downstream 100 bases:

>100_bases
TGGAGGAAATAGTTAAGATTAACGATTCCATTGTCCAGATAAGCGAATTAAGTGACAGAATATACGTAATGAAATTTGGA
AGAAATTCCATTTTAGAAAC

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNKVENTVDLKFLKKFSKDVTYNDWNDYKWQISNSIKSLDMLENVLEIKFPDNERKEIQKAIEVFPMSITPYYASLIDIS
NLKKDPIYKQSVASKKELIMEDFEMEDPLAEDKDSPVIGITHRYPDRVLFYVNPNCAMYCRHCTRKRKVSESESNPSKEE
IQKAIDYIKEHPEVRDVLLSGGDPLLLSDDYLDWILSEISSIEHVELIRIGSRVPVVLPQRITDNLVNILKKYHPIWVNT
HFNHVVEITDTSVEALDKLSNAGIPIGNQTVLLSGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSISKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGVITTYKEPSNYEGCSKNCNKCSRLSIDDF
EINQTGIEKLITNVDTSISLVPSNNKRMCRREK

Sequences:

>Translated_433_residues
MNKVENTVDLKFLKKFSKDVTYNDWNDYKWQISNSIKSLDMLENVLEIKFPDNERKEIQKAIEVFPMSITPYYASLIDIS
NLKKDPIYKQSVASKKELIMEDFEMEDPLAEDKDSPVIGITHRYPDRVLFYVNPNCAMYCRHCTRKRKVSESESNPSKEE
IQKAIDYIKEHPEVRDVLLSGGDPLLLSDDYLDWILSEISSIEHVELIRIGSRVPVVLPQRITDNLVNILKKYHPIWVNT
HFNHVVEITDTSVEALDKLSNAGIPIGNQTVLLSGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSISKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGVITTYKEPSNYEGCSKNCNKCSRLSIDDF
EINQTGIEKLITNVDTSISLVPSNNKRMCRREK
>Mature_433_residues
MNKVENTVDLKFLKKFSKDVTYNDWNDYKWQISNSIKSLDMLENVLEIKFPDNERKEIQKAIEVFPMSITPYYASLIDIS
NLKKDPIYKQSVASKKELIMEDFEMEDPLAEDKDSPVIGITHRYPDRVLFYVNPNCAMYCRHCTRKRKVSESESNPSKEE
IQKAIDYIKEHPEVRDVLLSGGDPLLLSDDYLDWILSEISSIEHVELIRIGSRVPVVLPQRITDNLVNILKKYHPIWVNT
HFNHVVEITDTSVEALDKLSNAGIPIGNQTVLLSGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSISKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGVITTYKEPSNYEGCSKNCNKCSRLSIDDF
EINQTGIEKLITNVDTSISLVPSNNKRMCRREK

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=328, Percent_Identity=32.6219512195122, Blast_Score=188, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 49540; Mature: 49540

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVENTVDLKFLKKFSKDVTYNDWNDYKWQISNSIKSLDMLENVLEIKFPDNERKEIQK
CCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHEEECCCCHHHHHHH
AIEVFPMSITPYYASLIDISNLKKDPIYKQSVASKKELIMEDFEMEDPLAEDKDSPVIGI
HHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
THRYPDRVLFYVNPNCAMYCRHCTRKRKVSESESNPSKEEIQKAIDYIKEHPEVRDVLLS
EECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHC
GGDPLLLSDDYLDWILSEISSIEHVELIRIGSRVPVVLPQRITDNLVNILKKYHPIWVNT
CCCCEEECCHHHHHHHHHHCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHCCEEEEC
HFNHVVEITDTSVEALDKLSNAGIPIGNQTVLLSGVNDCPYVMRKLNQKLVSSRVRPYYL
CCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
YQCDLSKGISHFRTSISKGLEIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHEECC
SDRVILRNYEGVITTYKEPSNYEGCSKNCNKCSRLSIDDFEINQTGIEKLITNVDTSISL
CCEEEEEECCCEEEECCCCCCCCCHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCEEEE
VPSNNKRMCRREK
ECCCCCCCCCCCC
>Mature Secondary Structure
MNKVENTVDLKFLKKFSKDVTYNDWNDYKWQISNSIKSLDMLENVLEIKFPDNERKEIQK
CCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHEEECCCCHHHHHHH
AIEVFPMSITPYYASLIDISNLKKDPIYKQSVASKKELIMEDFEMEDPLAEDKDSPVIGI
HHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
THRYPDRVLFYVNPNCAMYCRHCTRKRKVSESESNPSKEEIQKAIDYIKEHPEVRDVLLS
EECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHC
GGDPLLLSDDYLDWILSEISSIEHVELIRIGSRVPVVLPQRITDNLVNILKKYHPIWVNT
CCCCEEECCHHHHHHHHHHCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHCCEEEEC
HFNHVVEITDTSVEALDKLSNAGIPIGNQTVLLSGVNDCPYVMRKLNQKLVSSRVRPYYL
CCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
YQCDLSKGISHFRTSISKGLEIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHEECC
SDRVILRNYEGVITTYKEPSNYEGCSKNCNKCSRLSIDDFEINQTGIEKLITNVDTSISL
CCEEEEEECCCEEEECCCCCCCCCHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCEEEE
VPSNNKRMCRREK
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]