Click here to switch to the map view.

The map label for this gene is 150399956

Identifier: 150399956

GI number: 150399956

Start: 1237175

End: 1237939

Strand: Reverse

Name: 150399956

Synonym: Mevan_1213

Alternate gene names: NA

Gene position: 1237939-1237175 (Counterclockwise)

Preceding gene: 150399957

Following gene: 150399952

Centisome position: 71.97

GC content: 33.07

Gene sequence:

>765_bases
ATGGATCTAAAAATAGGAAAAATTGAAACTGAATTAAACAATATACTAAAAAAAGAAGGGGCATTATACTTTGTTTTAAT
TGACCCTGATGAAAAAAATTACGCTGAAGTTGCAGAAAAAGTAAAAGATTATGCCGATGCAATAATAATTGGTGGGAGTA
TCGGGATTACAAATCTTGATGAAGTTACAAAAAACATTAAAAAAATTACTAATCTTCCAGTAATACTGTTTCCAGGAAAC
GTTGATGGAGTTACTAAAGAAGCAGATGCTGTTTTATTCATGTCTTTGATGAATTCAAAAAATACATACTGGAATATGAC
TGCACCAACATTAGGGGCACTTACGATTAAAAAATACGGTCTTGAAGCAATTCCGATGGCATATTTAGGAATAGAGCCGA
TAAGTAAAACTGCAGTTGGATTTGTTGGAGAAGTTAATGAAATTCCACAAAAAAAGCCAGAAATTGCAAGCATATACTGT
CTCTCTGCATCTTACTTTGGAATGAGATGGGCATATTTAGAAGCAGGTAGCGGTGCAGAGTTTCCCGTAAGTAACGAAAT
GATTTTAATCTCAAAAAAGTTAAGCGGGATAAACTTAATAGTTGGAGGAGGCATTAGGTCTCCAGATGTCGCATATGAAA
AGGTAATAAGTGGCGCAGATGTAATTGTAACAGGTACACTTACTGAAAAAAATCCAGATGCTGTAAAAGAAATGAAAGAA
GCGATAAAAAGAGCTGGAAAAGATAAATTAAAAAATAAAAATTAA

Upstream 100 bases:

>100_bases
AATTAGCATGTTATGGTAAAAATTGGTAAAAATCAAATGATTAAATTTTAATACTGAATTAAAATATAAGTTTAAAAGAT
AGTTAGGCTAGAGGATTATC

Downstream 100 bases:

>100_bases
AATAATCTATTTTAATTTAATATTGGTTTACCACTACGATTTTTCCATTATTCCATTCTATGACATGATCTTTTGTTTTT
GAAAGGTCCAATATTGGCAC

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDLKIGKIETELNNILKKEGALYFVLIDPDEKNYAEVAEKVKDYADAIIIGGSIGITNLDEVTKNIKKITNLPVILFPGN
VDGVTKEADAVLFMSLMNSKNTYWNMTAPTLGALTIKKYGLEAIPMAYLGIEPISKTAVGFVGEVNEIPQKKPEIASIYC
LSASYFGMRWAYLEAGSGAEFPVSNEMILISKKLSGINLIVGGGIRSPDVAYEKVISGADVIVTGTLTEKNPDAVKEMKE
AIKRAGKDKLKNKN

Sequences:

>Translated_254_residues
MDLKIGKIETELNNILKKEGALYFVLIDPDEKNYAEVAEKVKDYADAIIIGGSIGITNLDEVTKNIKKITNLPVILFPGN
VDGVTKEADAVLFMSLMNSKNTYWNMTAPTLGALTIKKYGLEAIPMAYLGIEPISKTAVGFVGEVNEIPQKKPEIASIYC
LSASYFGMRWAYLEAGSGAEFPVSNEMILISKKLSGINLIVGGGIRSPDVAYEKVISGADVIVTGTLTEKNPDAVKEMKE
AIKRAGKDKLKNKN
>Mature_254_residues
MDLKIGKIETELNNILKKEGALYFVLIDPDEKNYAEVAEKVKDYADAIIIGGSIGITNLDEVTKNIKKITNLPVILFPGN
VDGVTKEADAVLFMSLMNSKNTYWNMTAPTLGALTIKKYGLEAIPMAYLGIEPISKTAVGFVGEVNEIPQKKPEIASIYC
LSASYFGMRWAYLEAGSGAEFPVSNEMILISKKLSGINLIVGGGIRSPDVAYEKVISGADVIVTGTLTEKNPDAVKEMKE
AIKRAGKDKLKNKN

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_METVS (A6URI9)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323723.1
- ProteinModelPortal:   A6URI9
- SMR:   A6URI9
- STRING:   A6URI9
- GeneID:   5325701
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_1213
- eggNOG:   arNOG05493
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 27582; Mature: 27582

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: BINDING 204-204

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKIGKIETELNNILKKEGALYFVLIDPDEKNYAEVAEKVKDYADAIIIGGSIGITNLD
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEECCCCCCCCHH
EVTKNIKKITNLPVILFPGNVDGVTKEADAVLFMSLMNSKNTYWNMTAPTLGALTIKKYG
HHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCC
LEAIPMAYLGIEPISKTAVGFVGEVNEIPQKKPEIASIYCLSASYFGMRWAYLEAGSGAE
CCCCCHHHCCCCCHHHHHHHHHCCHHHCCCCCCCEEEEEEEECHHCCEEEEEEECCCCCC
FPVSNEMILISKKLSGINLIVGGGIRSPDVAYEKVISGADVIVTGTLTEKNPDAVKEMKE
CCCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
AIKRAGKDKLKNKN
HHHHCCHHHCCCCC
>Mature Secondary Structure
MDLKIGKIETELNNILKKEGALYFVLIDPDEKNYAEVAEKVKDYADAIIIGGSIGITNLD
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEECCCCCCCCHH
EVTKNIKKITNLPVILFPGNVDGVTKEADAVLFMSLMNSKNTYWNMTAPTLGALTIKKYG
HHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCC
LEAIPMAYLGIEPISKTAVGFVGEVNEIPQKKPEIASIYCLSASYFGMRWAYLEAGSGAE
CCCCCHHHCCCCCHHHHHHHHHCCHHHCCCCCCCEEEEEEEECHHCCEEEEEEECCCCCC
FPVSNEMILISKKLSGINLIVGGGIRSPDVAYEKVISGADVIVTGTLTEKNPDAVKEMKE
CCCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
AIKRAGKDKLKNKN
HHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA