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The map label for this gene is 150399766

Identifier: 150399766

GI number: 150399766

Start: 1029326

End: 1030351

Strand: Reverse

Name: 150399766

Synonym: Mevan_1018

Alternate gene names: NA

Gene position: 1030351-1029326 (Counterclockwise)

Preceding gene: 150399767

Following gene: 150399765

Centisome position: 59.9

GC content: 36.26

Gene sequence:

>1026_bases
ATGAAAGTTACGGTATATGGTGCGGGTAACCAGAATCTTTATGTTAATCAACTAAAGTTACCTGAATCGTTTGGTGGTAC
TGCCCCTTATGGTGGGAGCAGAATGGCGATAGAATTTGCAAAAGCTGGCCACGAAGTTATTTTAGCAGAAATTAATAAAT
CAAACCTAAACGATGAACAATGGAGTATTGTTGAAAGTGCAGGAGTAAATGTTGTATCTGACGATATTGAAGCTTCAAAA
AATGCAGAAATCGCAATATTTTTCACTCCGTTTGGTAAAAAAACGGTTGAAATCGCTAAAAAAATTTTACCTCATCTTCC
AGAAAATGCAATAATTGCAAATACATGCACAGTTTCTCCTGTTACATTATACGCAATGCTTGAAGTTGAATTAAGAACCA
AACGAAAAGACATAGGTATTACTTCAATGCACCCAGCAGCAGTTCCGGGAACTCCTCAACATGGGCACTATGTAATAAGC
AATAAGGCTACAAATGGTACTTCATATGCAAATGATGAACAGATACAAAAATGTGTACGGCTTACTGAAAGTGTGGACAA
AGTGCCTTATTTAATCCCTGCAGATGTTTCAGCAACGGTTTCAGACATGGGTTCACTATTAACTGCAGTTACACTTTCAG
GTGTTTTAGATTACTATTCGGTTGGAACAAAAATTATTAAAGCTCCAAAGAAAATGGTAGAACAGCAAATTTTAATGACT
TTACAAACAATGGCATCCTTAGTTGAAACTTCGGGAGTAAATGGCCTTTTAAAAGCGTTAAATCCAGAATTACTTACAAA
AACTGCATCATCAATGCATCTACTTGAAAAACAAAAAGATTTAGATGCAGCACTCGATATTTTAAAGAGCTTAGATGGTG
AATTAAAGCACGCATCTGAAAATGCAGAAATAAAACCTACAACTCTTGTTGCAGCGCAATCTCTTGTTAAAGAATTAGAA
ACGTTAATTGGCGGGGCTGCAGCAAATGGTGCAATAAAAAGAAGTACTAGGAAGCTCTTCCAATAG

Upstream 100 bases:

>100_bases
ATAATTATGAGTTATTAGGTAATAATTGCATCGTAATAGAAAGGATTTAATAATTTGACTGCCTATAATAGTTACGTTTT
TATTTTTTAAAGGTGGTCTA

Downstream 100 bases:

>100_bases
GTGTAGTATGGTAAAAGAACTTAAAATTGTAGTAATGGGTTCAGAAGACGTTGGTAAAACATCACTCATGGATGCCTTAA
TTAAAAATGTTTCAAAAGTG

Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-like protein

Products: 5,10-methenyltetrahydromethanopterin; reduced coenzyme F420

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKVTVYGAGNQNLYVNQLKLPESFGGTAPYGGSRMAIEFAKAGHEVILAEINKSNLNDEQWSIVESAGVNVVSDDIEASK
NAEIAIFFTPFGKKTVEIAKKILPHLPENAIIANTCTVSPVTLYAMLEVELRTKRKDIGITSMHPAAVPGTPQHGHYVIS
NKATNGTSYANDEQIQKCVRLTESVDKVPYLIPADVSATVSDMGSLLTAVTLSGVLDYYSVGTKIIKAPKKMVEQQILMT
LQTMASLVETSGVNGLLKALNPELLTKTASSMHLLEKQKDLDAALDILKSLDGELKHASENAEIKPTTLVAAQSLVKELE
TLIGGAAANGAIKRSTRKLFQ

Sequences:

>Translated_341_residues
MKVTVYGAGNQNLYVNQLKLPESFGGTAPYGGSRMAIEFAKAGHEVILAEINKSNLNDEQWSIVESAGVNVVSDDIEASK
NAEIAIFFTPFGKKTVEIAKKILPHLPENAIIANTCTVSPVTLYAMLEVELRTKRKDIGITSMHPAAVPGTPQHGHYVIS
NKATNGTSYANDEQIQKCVRLTESVDKVPYLIPADVSATVSDMGSLLTAVTLSGVLDYYSVGTKIIKAPKKMVEQQILMT
LQTMASLVETSGVNGLLKALNPELLTKTASSMHLLEKQKDLDAALDILKSLDGELKHASENAEIKPTTLVAAQSLVKELE
TLIGGAAANGAIKRSTRKLFQ
>Mature_341_residues
MKVTVYGAGNQNLYVNQLKLPESFGGTAPYGGSRMAIEFAKAGHEVILAEINKSNLNDEQWSIVESAGVNVVSDDIEASK
NAEIAIFFTPFGKKTVEIAKKILPHLPENAIIANTCTVSPVTLYAMLEVELRTKRKDIGITSMHPAAVPGTPQHGHYVIS
NKATNGTSYANDEQIQKCVRLTESVDKVPYLIPADVSATVSDMGSLLTAVTLSGVLDYYSVGTKIIKAPKKMVEQQILMT
LQTMASLVETSGVNGLLKALNPELLTKTASSMHLLEKQKDLDAALDILKSLDGELKHASENAEIKPTTLVAAQSLVKELE
TLIGGAAANGAIKRSTRKLFQ

Specific function: Unknown

COG id: COG4007

COG function: function code R; Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR010063
- InterPro:   IPR004889
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03201 HMD [H]

EC number: 1.5.99.9

Molecular weight: Translated: 36634; Mature: 36634

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVYGAGNQNLYVNQLKLPESFGGTAPYGGSRMAIEFAKAGHEVILAEINKSNLNDEQ
CEEEEEECCCCCEEEEEEECCHHCCCCCCCCCCEEEEEEHHCCCEEEEEEECCCCCCCHH
WSIVESAGVNVVSDDIEASKNAEIAIFFTPFGKKTVEIAKKILPHLPENAIIANTCTVSP
HHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCC
VTLYAMLEVELRTKRKDIGITSMHPAAVPGTPQHGHYVISNKATNGTSYANDEQIQKCVR
EEEEHEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
LTESVDKVPYLIPADVSATVSDMGSLLTAVTLSGVLDYYSVGTKIIKAPKKMVEQQILMT
HHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTMASLVETSGVNGLLKALNPELLTKTASSMHLLEKQKDLDAALDILKSLDGELKHASE
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
NAEIKPTTLVAAQSLVKELETLIGGAAANGAIKRSTRKLFQ
CCCCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MKVTVYGAGNQNLYVNQLKLPESFGGTAPYGGSRMAIEFAKAGHEVILAEINKSNLNDEQ
CEEEEEECCCCCEEEEEEECCHHCCCCCCCCCCEEEEEEHHCCCEEEEEEECCCCCCCHH
WSIVESAGVNVVSDDIEASKNAEIAIFFTPFGKKTVEIAKKILPHLPENAIIANTCTVSP
HHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCC
VTLYAMLEVELRTKRKDIGITSMHPAAVPGTPQHGHYVISNKATNGTSYANDEQIQKCVR
EEEEHEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
LTESVDKVPYLIPADVSATVSDMGSLLTAVTLSGVLDYYSVGTKIIKAPKKMVEQQILMT
HHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTMASLVETSGVNGLLKALNPELLTKTASSMHLLEKQKDLDAALDILKSLDGELKHASE
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
NAEIKPTTLVAAQSLVKELETLIGGAAANGAIKRSTRKLFQ
CCCCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydromethanopterin; coenzyme F420

Specific reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]