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The map label for this gene is trpS [H]

Identifier: 150399654

GI number: 150399654

Start: 924590

End: 925666

Strand: Reverse

Name: trpS [H]

Synonym: Mevan_0904

Alternate gene names: 150399654

Gene position: 925666-924590 (Counterclockwise)

Preceding gene: 150399655

Following gene: 150399653

Centisome position: 53.82

GC content: 35.0

Gene sequence:

>1077_bases
TTGATTACTCCTTGGGAAGTTTCAGAGGACATCGACTATAAAAAGACAATGGAGCAATTTGGAGTAAATTCCATTTTTGA
TGTTGTAAAAAATTTGAAAAAGCCTCATAATTTTATGAATCGGGGAATAGTATTTGGACATCGGGACTTTCAAAGGATTT
TAGATGCCATAAACAATGGAAAAGATTTTACCGTAGTTTCTGGAATGATGCCTTCTGGAAAAATGCATTTTGGGCATAAA
ATGGTTGTAGACCAGCTTTTATATTATCAGAAATTAGGTGCAGATATATATATTCCTATTGCAGATTTGGAAGCTTATTG
GGCAAGAGGTATGGCCTTTGAAGCGACAAGAAAGATTGCAATCGAAGAATATATTACAAATTACATTGCACTTGGGCTAG
ACCCTGAAAAAATTAACGTATATCTTCAATCAAAAAATGAAAAAGTAAAAGACCTTGCAATGTTTCTTTCAAAAAAGGTT
AATTTTTCGGAAATGAAGGGAATTTACGGTTTTAGCGGTGAAACAAACATTGGACACGTTTTTGCACCCATAGTTCAGGT
TGCAGACATACTTCATCCTCAACTTGAAAAGAAAGTTCCAGTATTGGTTCCAGTTGGGATTGACCAAGACCCACATATAC
GGCTTACAAGAGATATATCTGGAAGATACAAGGATTTTGGATTTATCCCTCCTTCATCAACATACCATCGATTTATTACT
GGGCTTTTAGGTGGGAAAATGAGCTCTTCAAAGCCTGAAACTGCAATTTACCTTTCTGATGAACCCAATAAATCATTTAA
AAAGAAAATTATGTCATGTAAAACTGGGGGCAGGGAAACTCTCGAAGAACAGAAGCAATTTGGCGGAAAACCCGAAGAAT
GTGTTGTCTATGAAATTTACACGTACCACCTGATAGACGATGATAGCGAACTTAAAAAACTTTATGAACGCTGTAAAAGT
GGGGAATTAACGTGTGGAACATGTAAAAAAGAATGTTTTGAAAAATTGTCAGTATTCCTTAAAGAACTTCATGAAAAACG
TGAACAAGCAAAAGAAATTGCATCAAAACTCATTTAA

Upstream 100 bases:

>100_bases
AATAACCTTTAATATTTATTTAATTTATTTAATTTATTTACACTTTAAACTTTATGCTAGATTTTATCATTAATGAAATT
TAATTAATAAGGGTGAAATA

Downstream 100 bases:

>100_bases
TTTTTTTATTTTTCGGGAAATTATGATAAAAATAGTATATCTTACTAAAAATGCTGAAAATCTTGCAGAAAATGTTAAAA
CTATTTTAGATTATTATTTG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MITPWEVSEDIDYKKTMEQFGVNSIFDVVKNLKKPHNFMNRGIVFGHRDFQRILDAINNGKDFTVVSGMMPSGKMHFGHK
MVVDQLLYYQKLGADIYIPIADLEAYWARGMAFEATRKIAIEEYITNYIALGLDPEKINVYLQSKNEKVKDLAMFLSKKV
NFSEMKGIYGFSGETNIGHVFAPIVQVADILHPQLEKKVPVLVPVGIDQDPHIRLTRDISGRYKDFGFIPPSSTYHRFIT
GLLGGKMSSSKPETAIYLSDEPNKSFKKKIMSCKTGGRETLEEQKQFGGKPEECVVYEIYTYHLIDDDSELKKLYERCKS
GELTCGTCKKECFEKLSVFLKELHEKREQAKEIASKLI

Sequences:

>Translated_358_residues
MITPWEVSEDIDYKKTMEQFGVNSIFDVVKNLKKPHNFMNRGIVFGHRDFQRILDAINNGKDFTVVSGMMPSGKMHFGHK
MVVDQLLYYQKLGADIYIPIADLEAYWARGMAFEATRKIAIEEYITNYIALGLDPEKINVYLQSKNEKVKDLAMFLSKKV
NFSEMKGIYGFSGETNIGHVFAPIVQVADILHPQLEKKVPVLVPVGIDQDPHIRLTRDISGRYKDFGFIPPSSTYHRFIT
GLLGGKMSSSKPETAIYLSDEPNKSFKKKIMSCKTGGRETLEEQKQFGGKPEECVVYEIYTYHLIDDDSELKKLYERCKS
GELTCGTCKKECFEKLSVFLKELHEKREQAKEIASKLI
>Mature_358_residues
MITPWEVSEDIDYKKTMEQFGVNSIFDVVKNLKKPHNFMNRGIVFGHRDFQRILDAINNGKDFTVVSGMMPSGKMHFGHK
MVVDQLLYYQKLGADIYIPIADLEAYWARGMAFEATRKIAIEEYITNYIALGLDPEKINVYLQSKNEKVKDLAMFLSKKV
NFSEMKGIYGFSGETNIGHVFAPIVQVADILHPQLEKKVPVLVPVGIDQDPHIRLTRDISGRYKDFGFIPPSSTYHRFIT
GLLGGKMSSSKPETAIYLSDEPNKSFKKKIMSCKTGGRETLEEQKQFGGKPEECVVYEIYTYHLIDDDSELKKLYERCKS
GELTCGTCKKECFEKLSVFLKELHEKREQAKEIASKLI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI47419920, Length=383, Percent_Identity=30.5483028720627, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI47419918, Length=383, Percent_Identity=30.5483028720627, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI47419916, Length=383, Percent_Identity=30.5483028720627, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI47419914, Length=383, Percent_Identity=30.5483028720627, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1789786, Length=303, Percent_Identity=29.3729372937294, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72001474, Length=371, Percent_Identity=30.188679245283, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324475, Length=380, Percent_Identity=30.7894736842105, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6320474, Length=261, Percent_Identity=27.9693486590038, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17864462, Length=373, Percent_Identity=30.0268096514745, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24645295, Length=373, Percent_Identity=30.0268096514745, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- InterPro:   IPR020653 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40930; Mature: 40930

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPWEVSEDIDYKKTMEQFGVNSIFDVVKNLKKPHNFMNRGIVFGHRDFQRILDAINNG
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHCCC
KDFTVVSGMMPSGKMHFGHKMVVDQLLYYQKLGADIYIPIADLEAYWARGMAFEATRKIA
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHH
IEEYITNYIALGLDPEKINVYLQSKNEKVKDLAMFLSKKVNFSEMKGIYGFSGETNIGHV
HHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHH
FAPIVQVADILHPQLEKKVPVLVPVGIDQDPHIRLTRDISGRYKDFGFIPPSSTYHRFIT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
GLLGGKMSSSKPETAIYLSDEPNKSFKKKIMSCKTGGRETLEEQKQFGGKPEECVVYEIY
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEE
TYHLIDDDSELKKLYERCKSGELTCGTCKKECFEKLSVFLKELHEKREQAKEIASKLI
EEEEECCCHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITPWEVSEDIDYKKTMEQFGVNSIFDVVKNLKKPHNFMNRGIVFGHRDFQRILDAINNG
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHCCC
KDFTVVSGMMPSGKMHFGHKMVVDQLLYYQKLGADIYIPIADLEAYWARGMAFEATRKIA
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHH
IEEYITNYIALGLDPEKINVYLQSKNEKVKDLAMFLSKKVNFSEMKGIYGFSGETNIGHV
HHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHH
FAPIVQVADILHPQLEKKVPVLVPVGIDQDPHIRLTRDISGRYKDFGFIPPSSTYHRFIT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
GLLGGKMSSSKPETAIYLSDEPNKSFKKKIMSCKTGGRETLEEQKQFGGKPEECVVYEIY
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEE
TYHLIDDDSELKKLYERCKSGELTCGTCKKECFEKLSVFLKELHEKREQAKEIASKLI
EEEEECCCHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]