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The map label for this gene is hpsA [H]

Identifier: 150399334

GI number: 150399334

Start: 634067

End: 635380

Strand: Reverse

Name: hpsA [H]

Synonym: Mevan_0582

Alternate gene names: 150399334

Gene position: 635380-634067 (Counterclockwise)

Preceding gene: 150399335

Following gene: 150399332

Centisome position: 36.94

GC content: 37.37

Gene sequence:

>1314_bases
ATGGAAAACTATGACATACCTCCAGTTCAAGTTGCCCTTGACCTTTTAGACCTTCCAAGAGCAATAGAAATTGCAAAAGA
GGCGGTTTTAGGCGGGGTAACATGGATTGAAGCGGGAACTCCCCTCATAAAATCCGAAGGAATGAATGCAATCCGTAAAT
TAAGGGAAAATTTTCCAAATTTAACGATTGTAGCAGATATGAAAACAATGGATGCAGGAAGTACTGAAGTTGAAATGGCT
GCAAAAGCTGGAGCAGACGTTATATTGATACTTGGGGTAGGCCCTGATTCAATGATAAAAGAAGCAGTGCTTGCAGGAAA
AAAATACGGAGTATTGGTTGGAACTGACTTAATAGCTACATATGACCCTGTAGAACGTGCTTATGAACTTGAAAAACTGG
GTGTTGATATTATAAACATACACGTTGGACTTGACCAACAAGTTTTAAACATTGACCCTGTAGAACTCGTTAAAAAAGTT
TCAGAAAGATGTAAACACGCAAAAATTGCAGCAGCAGGTGGATTAAATAGTGAAACTGCTGTAAAAGCTTATGAAGCTGG
AGCAGATATAATAATTGTGGGCGGGCCACTTTATAAATCAGAAAGTCCTGAAAAAACTGCAAGGGACATTATTACAAGTT
TAAAGACTGGAAAACCAATATCAACCAGCAAATTTAAGAAATTTAATGAAAAAGAATTGTTAGATGCTTTTAAAATTGTC
AGCACTTCCAATATAAGCGATGCAATGCACAGAACTGGTGAAATGAGGGGATTAAAACCCGTAGTGGATTTTAAAAAACC
TTTGAAGTTTGCAGGGCCCGCGGTTACTGTTAGAACGTATGCAGGCGATTGGAGTAAACCTGTAAGTGCAATAGACGTAT
GCAGTGCCGGTGACGTTTTAGTAATTGATAATTGCGGTTCTGAAATTTCTTGCTGGGGCGGACTTGCAACACTTTCGTGC
AAAACAAAAGGTATAGTTGCAGTTATAGTAGATGGGGCTGTAAGGGACGTAGAAGAAATTTTAAAAATTGGAATTCCTGT
TTTTTCAAAAAGTATAACTCCAACAGCAGGTGAACCAAAAGGCTTTGGTGAAATAAATTCAGCAATTTTGTGTGCTGGAA
GAACTGTTGAACCTGGTGATTGGATTATTGGTGACGAAAATGGAATTATAGTAGTTCCAAAAAAAGATGCAATGGAAATT
GCAAATCGTGCAATAGATGTAAAAGAACGTGAAGATAGGGTTAAAGAAGAAATAAATCGTGGAAACACACTTGGAAAAGT
TATACGACTTAAAGATTGGGAATTAAAAAAATAA

Upstream 100 bases:

>100_bases
CATTTAATTGACTACAATGTATTTTTAAATAATTTTTTTAGTTTTTATATTTTATTTTAACTGCCAATTTAATTACTTTT
TATTTTAAAAAGGTGATATT

Downstream 100 bases:

>100_bases
TATATCCCTTTTTTAAAATCTTTTAAAAAATAAAATTGTTATTTTGAACATATATTACTTTTAATAATATTAAGCTTAAT
TATATTATTTTTTATACCTG

Product: bifunctional hexulose-6-phosphate synthase/ribonuclease regulator

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MENYDIPPVQVALDLLDLPRAIEIAKEAVLGGVTWIEAGTPLIKSEGMNAIRKLRENFPNLTIVADMKTMDAGSTEVEMA
AKAGADVILILGVGPDSMIKEAVLAGKKYGVLVGTDLIATYDPVERAYELEKLGVDIINIHVGLDQQVLNIDPVELVKKV
SERCKHAKIAAAGGLNSETAVKAYEAGADIIIVGGPLYKSESPEKTARDIITSLKTGKPISTSKFKKFNEKELLDAFKIV
STSNISDAMHRTGEMRGLKPVVDFKKPLKFAGPAVTVRTYAGDWSKPVSAIDVCSAGDVLVIDNCGSEISCWGGLATLSC
KTKGIVAVIVDGAVRDVEEILKIGIPVFSKSITPTAGEPKGFGEINSAILCAGRTVEPGDWIIGDENGIIVVPKKDAMEI
ANRAIDVKEREDRVKEEINRGNTLGKVIRLKDWELKK

Sequences:

>Translated_437_residues
MENYDIPPVQVALDLLDLPRAIEIAKEAVLGGVTWIEAGTPLIKSEGMNAIRKLRENFPNLTIVADMKTMDAGSTEVEMA
AKAGADVILILGVGPDSMIKEAVLAGKKYGVLVGTDLIATYDPVERAYELEKLGVDIINIHVGLDQQVLNIDPVELVKKV
SERCKHAKIAAAGGLNSETAVKAYEAGADIIIVGGPLYKSESPEKTARDIITSLKTGKPISTSKFKKFNEKELLDAFKIV
STSNISDAMHRTGEMRGLKPVVDFKKPLKFAGPAVTVRTYAGDWSKPVSAIDVCSAGDVLVIDNCGSEISCWGGLATLSC
KTKGIVAVIVDGAVRDVEEILKIGIPVFSKSITPTAGEPKGFGEINSAILCAGRTVEPGDWIIGDENGIIVVPKKDAMEI
ANRAIDVKEREDRVKEEINRGNTLGKVIRLKDWELKK
>Mature_437_residues
MENYDIPPVQVALDLLDLPRAIEIAKEAVLGGVTWIEAGTPLIKSEGMNAIRKLRENFPNLTIVADMKTMDAGSTEVEMA
AKAGADVILILGVGPDSMIKEAVLAGKKYGVLVGTDLIATYDPVERAYELEKLGVDIINIHVGLDQQVLNIDPVELVKKV
SERCKHAKIAAAGGLNSETAVKAYEAGADIIIVGGPLYKSESPEKTARDIITSLKTGKPISTSKFKKFNEKELLDAFKIV
STSNISDAMHRTGEMRGLKPVVDFKKPLKFAGPAVTVRTYAGDWSKPVSAIDVCSAGDVLVIDNCGSEISCWGGLATLSC
KTKGIVAVIVDGAVRDVEEILKIGIPVFSKSITPTAGEPKGFGEINSAILCAGRTVEPGDWIIGDENGIIVVPKKDAMEI
ANRAIDVKEREDRVKEEINRGNTLGKVIRLKDWELKK

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=144, Percent_Identity=31.25, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 46944; Mature: 46944

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYDIPPVQVALDLLDLPRAIEIAKEAVLGGVTWIEAGTPLIKSEGMNAIRKLRENFPN
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCHHHCCHHHHHHHHHHCCC
LTIVADMKTMDAGSTEVEMAAKAGADVILILGVGPDSMIKEAVLAGKKYGVLVGTDLIAT
EEEEEECEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEECCHHCC
YDPVERAYELEKLGVDIINIHVGLDQQVLNIDPVELVKKVSERCKHAKIAAAGGLNSETA
CCHHHHHHHHHHCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHCEEEECCCCCCCHH
VKAYEAGADIIIVGGPLYKSESPEKTARDIITSLKTGKPISTSKFKKFNEKELLDAFKIV
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHH
STSNISDAMHRTGEMRGLKPVVDFKKPLKFAGPAVTVRTYAGDWSKPVSAIDVCSAGDVL
CCCCHHHHHHHHCCCCCCCHHHHHHCCHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCEE
VIDNCGSEISCWGGLATLSCKTKGIVAVIVDGAVRDVEEILKIGIPVFSKSITPTAGEPK
EEECCCCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHHHHCCCHHHCCCCCCCCCCCC
GFGEINSAILCAGRTVEPGDWIIGDENGIIVVPKKDAMEIANRAIDVKEREDRVKEEINR
CCCCCCCEEEECCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHC
GNTLGKVIRLKDWELKK
CCCHHHEEEECCCCCCC
>Mature Secondary Structure
MENYDIPPVQVALDLLDLPRAIEIAKEAVLGGVTWIEAGTPLIKSEGMNAIRKLRENFPN
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCHHHCCHHHHHHHHHHCCC
LTIVADMKTMDAGSTEVEMAAKAGADVILILGVGPDSMIKEAVLAGKKYGVLVGTDLIAT
EEEEEECEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEECCHHCC
YDPVERAYELEKLGVDIINIHVGLDQQVLNIDPVELVKKVSERCKHAKIAAAGGLNSETA
CCHHHHHHHHHHCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHCEEEECCCCCCCHH
VKAYEAGADIIIVGGPLYKSESPEKTARDIITSLKTGKPISTSKFKKFNEKELLDAFKIV
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHH
STSNISDAMHRTGEMRGLKPVVDFKKPLKFAGPAVTVRTYAGDWSKPVSAIDVCSAGDVL
CCCCHHHHHHHHCCCCCCCHHHHHHCCHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCEE
VIDNCGSEISCWGGLATLSCKTKGIVAVIVDGAVRDVEEILKIGIPVFSKSITPTAGEPK
EEECCCCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHHHHCCCHHHCCCCCCCCCCCC
GFGEINSAILCAGRTVEPGDWIIGDENGIIVVPKKDAMEIANRAIDVKEREDRVKEEINR
CCCCCCCEEEECCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHC
GNTLGKVIRLKDWELKK
CCCHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA