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The map label for this gene is modD [H]

Identifier: 150399296

GI number: 150399296

Start: 599172

End: 600023

Strand: Reverse

Name: modD [H]

Synonym: Mevan_0544

Alternate gene names: 150399296

Gene position: 600023-599172 (Counterclockwise)

Preceding gene: 150399298

Following gene: 150399291

Centisome position: 34.88

GC content: 30.05

Gene sequence:

>852_bases
ATGTCATTTTATATAGCTGATTCTGAATTAGAAAAAATAATTGAAGAAGACGTAAATCCATTAGATTTAACTTCACAATT
AATGGACTTAAGTAGATTTAATGCAAAAATTTCATACATTGCAAGACATGACATGGTAATATGTTGTACTGAGGAATCCG
CAAGAATCTGTACTACTATAGGACTAACTGTAAAAAATTATTTAAGTTCGGGAACCTTTGTAAAAAAAGGCCAGGTATTT
TTTGAAGCATTTGGAAGAGCGGATAAAATCCACCTCGCATGGAAAAGTGTTTTAAGATTACTTGAGGGATATTCTGGAAT
TGCTACAAAAACAAAGGAATTTGTAGATATTTCAAAAAAGTACAACAATCATGTAAATATAGTAACAACTAGAAAAAGCG
CTGCTGGAACTAAAAAACTCTCAATAAAGGCAGTAATTTCAGGAGGTGCTTATCCTCATAGGATGGGGCTATCAGAGACA
GTTCTGATTTTTAATGAACACCTTATATTTTTAAAAGATGATTCAGAACTCCAAAACACTTTGGAAATAATGAAATCAAA
AGTTCTTGAAAAGAAAATAGGAATAGAAACAGATAATCATGAAATTGGGTTGAAATATGTTAAAATGGGTTTTGATTTTA
TTCAACTTGATAAATTAAGTCCAAAAGAGGTAGAAAACTTTATTAAAGATGCTAAATCAGTAAACCAGAAAATAACTGTG
GCTTGTGCAGGTGGAATTAATATTGAAAATATTGAAGAATATGCAAAAACAGGTGTTGACGTTATAGTTACTTCATCGCT
TTATTTTACAAAGCCTGCGGATATAAAAGCATTAATTGAAAAAATAGATTAA

Upstream 100 bases:

>100_bases
GTAACCTATAAAAAATGCCATTATTTGAAATTTAAATGGCAAATAATATATGTTAAAATAAATATTTAGATTAATAAATT
ATAATAATTTGAGGGTTAAA

Downstream 100 bases:

>100_bases
TATTTTTCAAATAATTTAAAAATTACTTTTTAATCTTACATATTCATTAAACGCTTCTCTGGTAGTTCCAACAACAACTC
GTTTATAGCATTTTTTCCCG

Product: modD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSFYIADSELEKIIEEDVNPLDLTSQLMDLSRFNAKISYIARHDMVICCTEESARICTTIGLTVKNYLSSGTFVKKGQVF
FEAFGRADKIHLAWKSVLRLLEGYSGIATKTKEFVDISKKYNNHVNIVTTRKSAAGTKKLSIKAVISGGAYPHRMGLSET
VLIFNEHLIFLKDDSELQNTLEIMKSKVLEKKIGIETDNHEIGLKYVKMGFDFIQLDKLSPKEVENFIKDAKSVNQKITV
ACAGGINIENIEEYAKTGVDVIVTSSLYFTKPADIKALIEKID

Sequences:

>Translated_283_residues
MSFYIADSELEKIIEEDVNPLDLTSQLMDLSRFNAKISYIARHDMVICCTEESARICTTIGLTVKNYLSSGTFVKKGQVF
FEAFGRADKIHLAWKSVLRLLEGYSGIATKTKEFVDISKKYNNHVNIVTTRKSAAGTKKLSIKAVISGGAYPHRMGLSET
VLIFNEHLIFLKDDSELQNTLEIMKSKVLEKKIGIETDNHEIGLKYVKMGFDFIQLDKLSPKEVENFIKDAKSVNQKITV
ACAGGINIENIEEYAKTGVDVIVTSSLYFTKPADIKALIEKID
>Mature_282_residues
SFYIADSELEKIIEEDVNPLDLTSQLMDLSRFNAKISYIARHDMVICCTEESARICTTIGLTVKNYLSSGTFVKKGQVFF
EAFGRADKIHLAWKSVLRLLEGYSGIATKTKEFVDISKKYNNHVNIVTTRKSAAGTKKLSIKAVISGGAYPHRMGLSETV
LIFNEHLIFLKDDSELQNTLEIMKSKVLEKKIGIETDNHEIGLKYVKMGFDFIQLDKLSPKEVENFIKDAKSVNQKITVA
CAGGINIENIEEYAKTGVDVIVTSSLYFTKPADIKALIEKID

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Escherichia coli, GI1786299, Length=250, Percent_Identity=25.6, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321162, Length=271, Percent_Identity=23.9852398523985, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 31705; Mature: 31574

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYIADSELEKIIEEDVNPLDLTSQLMDLSRFNAKISYIARHDMVICCTEESARICTTI
CEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCEEHHH
GLTVKNYLSSGTFVKKGQVFFEAFGRADKIHLAWKSVLRLLEGYSGIATKTKEFVDISKK
HHHHHHHHCCCCEEECCHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
YNNHVNIVTTRKSAAGTKKLSIKAVISGGAYPHRMGLSETVLIFNEHLIFLKDDSELQNT
HCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECEEEEEECCHHHHHH
LEIMKSKVLEKKIGIETDNHEIGLKYVKMGFDFIQLDKLSPKEVENFIKDAKSVNQKITV
HHHHHHHHHHHHHCCCCCCCHHCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCEEEE
ACAGGINIENIEEYAKTGVDVIVTSSLYFTKPADIKALIEKID
EEECCCCHHHHHHHHHCCCEEEEECCEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SFYIADSELEKIIEEDVNPLDLTSQLMDLSRFNAKISYIARHDMVICCTEESARICTTI
EEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCEEHHH
GLTVKNYLSSGTFVKKGQVFFEAFGRADKIHLAWKSVLRLLEGYSGIATKTKEFVDISKK
HHHHHHHHCCCCEEECCHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
YNNHVNIVTTRKSAAGTKKLSIKAVISGGAYPHRMGLSETVLIFNEHLIFLKDDSELQNT
HCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECEEEEEECCHHHHHH
LEIMKSKVLEKKIGIETDNHEIGLKYVKMGFDFIQLDKLSPKEVENFIKDAKSVNQKITV
HHHHHHHHHHHHHCCCCCCCHHCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCEEEE
ACAGGINIENIEEYAKTGVDVIVTSSLYFTKPADIKALIEKID
EEECCCCHHHHHHHHHCCCEEEEECCEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]