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The map label for this gene is dut [H]

Identifier: 150399151

GI number: 150399151

Start: 451343

End: 451813

Strand: Reverse

Name: dut [H]

Synonym: Mevan_0398

Alternate gene names: 150399151

Gene position: 451813-451343 (Counterclockwise)

Preceding gene: 150399152

Following gene: 150399148

Centisome position: 26.27

GC content: 31.21

Gene sequence:

>471_bases
ATGATTATTGGTCCAAATATTTCAAAAGAATTTTTATCCGATTTAAAAGAAGGCCAGCTTCAACAGTGTGGGATTGACTT
AAAACTTGATAAAATCTATAAAATCTCCGGAAACGGTTCAATTGATTTCTCAAATGAAAAACGGGTTCTTCCTGAGCACG
TTTTAATTTTTGATTCGGAAAAAGACGAAAAAATTGACCTTGAATGTGGGATTTATGTTGTAAAAATTAATGAAAAAATG
AAAATTCCAGAAAATTTGGCAGGTTTTGTACTTCCAAGAAGTACTTTTCTTAGAATGGGCGTAACGTTTTATACGGCAGT
ACATGATCCGGGATACGAGGGTTATGCAAGTTATTTAATGCATGTTATGAATCCGGTAACCATGTATAAATACGCTAAAA
TTGCACAAATAGTATTTTTTGAAGTTAAAAATCCAAACGGAACTTATGATGGAATTTATAATAAAAAATAG

Upstream 100 bases:

>100_bases
AATTCAATTATTGGTGCAAATTGCCTAGTTGATAAAGATATTGAAAAAGAAAGCTTTGTTTATAAAAAAGACGAATTAAT
AATTAAAAAGAGGAATTAAA

Downstream 100 bases:

>100_bases
GTATTTTATAAATATTTAATTTTTTATTAAATTTTAAATATTATTCATCAAGCCTTTGTGTTCTTCTAACTGTAAATGCG
AAAAATGCGGGTAATACTGC

Product: deoxyUTP pyrophosphatase

Products: NA

Alternate protein names: dUTPase; MjDUT; dUTP pyrophosphatase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MIIGPNISKEFLSDLKEGQLQQCGIDLKLDKIYKISGNGSIDFSNEKRVLPEHVLIFDSEKDEKIDLECGIYVVKINEKM
KIPENLAGFVLPRSTFLRMGVTFYTAVHDPGYEGYASYLMHVMNPVTMYKYAKIAQIVFFEVKNPNGTYDGIYNKK

Sequences:

>Translated_156_residues
MIIGPNISKEFLSDLKEGQLQQCGIDLKLDKIYKISGNGSIDFSNEKRVLPEHVLIFDSEKDEKIDLECGIYVVKINEKM
KIPENLAGFVLPRSTFLRMGVTFYTAVHDPGYEGYASYLMHVMNPVTMYKYAKIAQIVFFEVKNPNGTYDGIYNKK
>Mature_156_residues
MIIGPNISKEFLSDLKEGQLQQCGIDLKLDKIYKISGNGSIDFSNEKRVLPEHVLIFDSEKDEKIDLECGIYVVKINEKM
KIPENLAGFVLPRSTFLRMGVTFYTAVHDPGYEGYASYLMHVMNPVTMYKYAKIAQIVFFEVKNPNGTYDGIYNKK

Specific function: This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [H]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family. Archaeal dUTPase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008180 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.6.1.23 [H]

Molecular weight: Translated: 17815; Mature: 17815

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGPNISKEFLSDLKEGQLQQCGIDLKLDKIYKISGNGSIDFSNEKRVLPEHVLIFDSE
CEECCCCCHHHHHHHHCCCHHHCCCCEEEEEEEEECCCCCEEECCCCCCCCCEEEEEECC
KDEKIDLECGIYVVKINEKMKIPENLAGFVLPRSTFLRMGVTFYTAVHDPGYEGYASYLM
CCCEEEEEECEEEEEECCCCCCCCCHHCEECCCHHHHHHCEEEEEEECCCCCHHHHHHHH
HVMNPVTMYKYAKIAQIVFFEVKNPNGTYDGIYNKK
HHHCHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIIGPNISKEFLSDLKEGQLQQCGIDLKLDKIYKISGNGSIDFSNEKRVLPEHVLIFDSE
CEECCCCCHHHHHHHHCCCHHHCCCCEEEEEEEEECCCCCEEECCCCCCCCCEEEEEECC
KDEKIDLECGIYVVKINEKMKIPENLAGFVLPRSTFLRMGVTFYTAVHDPGYEGYASYLM
CCCEEEEEECEEEEEECCCCCCCCCHHCEECCCHHHHHHCEEEEEEECCCCCHHHHHHHH
HVMNPVTMYKYAKIAQIVFFEVKNPNGTYDGIYNKK
HHHCHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 12538648 [H]