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The map label for this gene is yfdZ [C]

Identifier: 150399148

GI number: 150399148

Start: 449551

End: 450678

Strand: Reverse

Name: yfdZ [C]

Synonym: Mevan_0395

Alternate gene names: 150399148

Gene position: 450678-449551 (Counterclockwise)

Preceding gene: 150399151

Following gene: 150399147

Centisome position: 26.2

GC content: 31.21

Gene sequence:

>1128_bases
ATGATTTCAAACAGGTGTTTAGGAACAGAACAGTCCGAAATTAGGAAAATATTTAACATGGCAACAGAAAACTCGATAAA
TTTGGGAATTGGAGAACCGGACTTTGACACTCCAAAAAACATAGTTGAGGCTGCAAAAACAGCACTTTTAAATGGGAAAA
CCCATTATTCTCCCAATGCAGGAATTTTAGAACTTACAAACGCAATTTCTGAAAAATTAAAAAAAGATAATAATTTAGAT
GTTCCAAGAAATAATATTATTACAACGTGTGGTGCATCCGAAGCACTGATGCTTTCATTATTTACTCTAGTTAATAAAAA
TGAAGAGGTTTTAATTCCTGACCCCGGATTTGTGTCGTATAAAGGACTAACTGAACTTTCAGAAGGGAAAGTTATTCCGG
TAAATCTTGATGATAAATTTAAAATTGATTTAGAATCCCTAAAAAACAACATTTCTAAAAAAACGAAATGTATAATTTTA
AATTCGCCTTCAAACCCTACTGGAAGCGTAATAACAAAAGAAGAAATCAAAGGAGTCTGTGAAATTGCAGGGGATAACAA
TATTACAGTAATTTCTGATGAAATTTATGAAAAAATAATTTATGGGAAAAAACATTATTCTGCAATGGAATTTACCGATA
ATTCAATAGTGATTAACGGATTTTCAAAAGCTTATTCAATGACTGGATGGAGGATTGGGTATCTAGCAGTAAATGAAAAC
TTCGATAAAAAATATAATCTTATTGAAAATATGATGAAAATTCACCAGTACGGATTTGCTTGCGCAACTTCTTTTGCTCA
ATATGGGGCATTTGAAGCACTTACTGGTGACCAAAAAAGCGTTTTTGAAATGGTTTTAGAGTTTGAAAAAAGAAGAAACT
TGATATATACTGGATTAAAAGATATATTCAATGTTCAAAAACCAGAAGGGGCATTTTATATATTCCCTGACGTCAGTGAA
TATGGTAATGGAATGGAAGTTGCAACAAAATTGATTAAAAATAATATATTATGCGTTCCAGGGTCAGCATTTGGAAAACA
GGGTGAAAACAGGGTTAGATTTTCATATGCTACTAAATATGAAGACATTGAAAAGGCAATAGAAATAATGAAAAATGTTC
TTCTTTAA

Upstream 100 bases:

>100_bases
ACGTTGAAGCGAATAATAACTTTACGAGTACATATCTAACAGAATAATAATGATTAATCATTATAGTTCTTGATTATATA
TAATTATCTAAGGTGGTAGT

Downstream 100 bases:

>100_bases
ATTTTAAAAATTCTTAAAATTTTATTAACTGGACTTTCATTAATTAAAATTTTATTAATTAGTATATATTCAAAAATTTC
TTTAAGATCTGTTAGTGATA

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MISNRCLGTEQSEIRKIFNMATENSINLGIGEPDFDTPKNIVEAAKTALLNGKTHYSPNAGILELTNAISEKLKKDNNLD
VPRNNIITTCGASEALMLSLFTLVNKNEEVLIPDPGFVSYKGLTELSEGKVIPVNLDDKFKIDLESLKNNISKKTKCIIL
NSPSNPTGSVITKEEIKGVCEIAGDNNITVISDEIYEKIIYGKKHYSAMEFTDNSIVINGFSKAYSMTGWRIGYLAVNEN
FDKKYNLIENMMKIHQYGFACATSFAQYGAFEALTGDQKSVFEMVLEFEKRRNLIYTGLKDIFNVQKPEGAFYIFPDVSE
YGNGMEVATKLIKNNILCVPGSAFGKQGENRVRFSYATKYEDIEKAIEIMKNVLL

Sequences:

>Translated_375_residues
MISNRCLGTEQSEIRKIFNMATENSINLGIGEPDFDTPKNIVEAAKTALLNGKTHYSPNAGILELTNAISEKLKKDNNLD
VPRNNIITTCGASEALMLSLFTLVNKNEEVLIPDPGFVSYKGLTELSEGKVIPVNLDDKFKIDLESLKNNISKKTKCIIL
NSPSNPTGSVITKEEIKGVCEIAGDNNITVISDEIYEKIIYGKKHYSAMEFTDNSIVINGFSKAYSMTGWRIGYLAVNEN
FDKKYNLIENMMKIHQYGFACATSFAQYGAFEALTGDQKSVFEMVLEFEKRRNLIYTGLKDIFNVQKPEGAFYIFPDVSE
YGNGMEVATKLIKNNILCVPGSAFGKQGENRVRFSYATKYEDIEKAIEIMKNVLL
>Mature_375_residues
MISNRCLGTEQSEIRKIFNMATENSINLGIGEPDFDTPKNIVEAAKTALLNGKTHYSPNAGILELTNAISEKLKKDNNLD
VPRNNIITTCGASEALMLSLFTLVNKNEEVLIPDPGFVSYKGLTELSEGKVIPVNLDDKFKIDLESLKNNISKKTKCIIL
NSPSNPTGSVITKEEIKGVCEIAGDNNITVISDEIYEKIIYGKKHYSAMEFTDNSIVINGFSKAYSMTGWRIGYLAVNEN
FDKKYNLIENMMKIHQYGFACATSFAQYGAFEALTGDQKSVFEMVLEFEKRRNLIYTGLKDIFNVQKPEGAFYIFPDVSE
YGNGMEVATKLIKNNILCVPGSAFGKQGENRVRFSYATKYEDIEKAIEIMKNVLL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=340, Percent_Identity=28.2352941176471, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI95147551, Length=411, Percent_Identity=25.0608272506083, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI169881279, Length=411, Percent_Identity=25.0608272506083, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=26.7002518891688, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=26.7002518891688, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI169881281, Length=403, Percent_Identity=22.0843672456576, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=28.4574468085106, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=24.8633879781421, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788627, Length=361, Percent_Identity=28.5318559556787, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787710, Length=342, Percent_Identity=21.3450292397661, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=26.75, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17567663, Length=362, Percent_Identity=27.3480662983425, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=26.75, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17567369, Length=247, Percent_Identity=29.5546558704453, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=382, Percent_Identity=22.2513089005236, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=27.9487179487179, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=352, Percent_Identity=25.5681818181818, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=23.5795454545455, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=25.952380952381, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=25.952380952381, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=25.952380952381, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=25.952380952381, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=25.6410256410256, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45551451, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641770, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641760, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641768, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641766, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641764, Length=390, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356535, Length=380, Percent_Identity=22.8947368421053, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41877; Mature: 41877

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNRCLGTEQSEIRKIFNMATENSINLGIGEPDFDTPKNIVEAAKTALLNGKTHYSPNA
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GILELTNAISEKLKKDNNLDVPRNNIITTCGASEALMLSLFTLVNKNEEVLIPDPGFVSY
CHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCEEE
KGLTELSEGKVIPVNLDDKFKIDLESLKNNISKKTKCIILNSPSNPTGSVITKEEIKGVC
CCCCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCCCEEHHHHCCEE
EIAGDNNITVISDEIYEKIIYGKKHYSAMEFTDNSIVINGFSKAYSMTGWRIGYLAVNEN
EECCCCCEEEECHHHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHCCCEEEEEEEECCC
FDKKYNLIENMMKIHQYGFACATSFAQYGAFEALTGDQKSVFEMVLEFEKRRNLIYTGLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCHHHHCHH
DIFNVQKPEGAFYIFPDVSEYGNGMEVATKLIKNNILCVPGSAFGKQGENRVRFSYATKY
HHHCCCCCCCCEEECCCHHHHCCHHHHHHHHHHCCEEEECCHHHCCCCCCEEEEEEHHHH
EDIEKAIEIMKNVLL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MISNRCLGTEQSEIRKIFNMATENSINLGIGEPDFDTPKNIVEAAKTALLNGKTHYSPNA
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GILELTNAISEKLKKDNNLDVPRNNIITTCGASEALMLSLFTLVNKNEEVLIPDPGFVSY
CHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCEEE
KGLTELSEGKVIPVNLDDKFKIDLESLKNNISKKTKCIILNSPSNPTGSVITKEEIKGVC
CCCCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCCCEEHHHHCCEE
EIAGDNNITVISDEIYEKIIYGKKHYSAMEFTDNSIVINGFSKAYSMTGWRIGYLAVNEN
EECCCCCEEEECHHHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHCCCEEEEEEEECCC
FDKKYNLIENMMKIHQYGFACATSFAQYGAFEALTGDQKSVFEMVLEFEKRRNLIYTGLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCHHHHCHH
DIFNVQKPEGAFYIFPDVSEYGNGMEVATKLIKNNILCVPGSAFGKQGENRVRFSYATKY
HHHCCCCCCCCEEECCCHHHHCCHHHHHHHHHHCCEEEECCHHHCCCCCCEEEEEEHHHH
EDIEKAIEIMKNVLL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]