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The map label for this gene is argS

Identifier: 150399104

GI number: 150399104

Start: 403500

End: 405209

Strand: Reverse

Name: argS

Synonym: Mevan_0350

Alternate gene names: 150399104

Gene position: 405209-403500 (Counterclockwise)

Preceding gene: 150399107

Following gene: 150399103

Centisome position: 23.56

GC content: 32.11

Gene sequence:

>1710_bases
ATGGACGTTAAAAAATTGATAGTGGTTGCAATTGAGAAAAAAGTACTGGATTTAACGGGAAAACAAATCGAAATCAGACT
TGATGAACCTCCTTCCATAAATATGGGGGATTATTCAACAAACATTGCATTCCGACTTTCAAAAGAGCTTAAAAAGGCCC
CAAAAATAATTGCGGAGGAAATTACCTCATCTTTAAGTATTCCGGGAATTGAAAAAATAGAAAGTTTGAATGGCTACATT
AATTTTTTCATGGATTATTCTGTTTTTTCAAAAGAAACTACTTTAGAAATTAACTCAAAACAGGAAAATTTTGGAAAAAG
CGATTTAAAAAATAAAAAAGTTATTTTAGAGCATACTTCGGCAAATCCTAATGGCCCATTTCATATTGGACATGGTAGAA
ACATGGTTATTGGGGACAGCTTAAAAAGAATACTGAATGCAGCAGGATATACTGTAGAAACCCAGTATTATGTAAATGAT
ATGGGTAGGCAAGAAGCAATTGTTGTTTTTGGAAATGATAGATTTAAACTCGATAAATCGAAAAAATCTGACCATGCAAT
TGGACAAACGTATGTTGAAGCAAATAAGTTACTAAATGAGAATGAAGAGTTAGAGCAAGAAATTCTAAACTTAATGAAAA
ATTATGAAGAAGCAATGGAAAATGGCATTGAAAATGAAATTACTGAAAAATTTAAGAATGCCGTAGAATATGCCCTCACT
GGATTTAAGGAAACGCTTTCAACATTAAACATACATCACGATAAATTTGTCTGGGAAAGTGAATTTGTAAGAAGTGGACT
GGTTAGAAATGTAATAAATAGATTAATGGAAACTGGAAAAGTTACCGAAGAAGATGTTTATAGGTTGGATCTTTCTGAAT
TTGGAATAGAAAAAAAGTTGGTTCTTGCAAGACTTAACGGTACGAGCTTATATTCAACAAGGGACGTTGCTTATCACATG
ACTAAAATGGAAAACTGTGATTTTGCAGTAAATTTACTTGGTGCAGACCACAAACTAACTGGAATAATGGTAAACAAAAC
GCTTGCACTTTTAGGATACAATGAGGCGGAAATTGTATTTTATGAATTTATTTCGCTTCCTGAAGGTTCAATGAGTACAA
GGCAAGGACGATTTATCAGTATGGATGAATTATTTGAAGAAGCAAAATTAAGGGCAAGAGAAGAAGTTAAAAAAAGAGAA
GTAGCAAAAACAGAAGAGGAAATCGAAGAAATTGCAAAAAAAATTGCAGTTGGGGCAGTAAGATATAATATTGTTAGAAT
TTCGCCTGAAAAACCCATGGTATTCCGATGGGATGAAGCTCTTGACTTTGAAAAGGTAGGGTGCCCAGTAATTCAGTATG
CCCATGCAAGATGTTCGAGAATTTTAGAAAATTGCGAACCTTCAGGTTTAGTAAATTCAAAAAATTTGTTTGAATATGAA
ATGGCTGAAAATGAAAAAATAATTGTAAAACTGATTTCAAAACTTCCTGAAATTGTTGAAAAGTCAGCAGAAGTTAGAAA
ACCGCAGATTTTAGCAAACTATGCACTTGAACTAGCACAAGGATTTAATAAATTTTATGGAAACTGTAGAATATTAAAAG
AAGAAAATGAAACCGTTAGAAATTCAAGAATTATGATTGTAAACTCTACAAAATTAGTTTTAGAAAATTCTCTTGACCTT
TTAGGTATCGAAATGCCTGGAAAAATGTAA

Upstream 100 bases:

>100_bases
ATATATATTACTTTTAAAGTCTTAAAATATTTAAACATTCTTAAATATACTTAAATATACCCAAATACTCTTAAATTTTG
AAAACACGGCGAGGCATAAT

Downstream 100 bases:

>100_bases
ATTTATTTTTATTTTTATTTTAAAATTATACGTAAAGTTTAGATATAATAATACAACTTTAGTTTTAAATTTATTAAAAG
ACTATTAAAATAGATTATTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDVKKLIVVAIEKKVLDLTGKQIEIRLDEPPSINMGDYSTNIAFRLSKELKKAPKIIAEEITSSLSIPGIEKIESLNGYI
NFFMDYSVFSKETTLEINSKQENFGKSDLKNKKVILEHTSANPNGPFHIGHGRNMVIGDSLKRILNAAGYTVETQYYVND
MGRQEAIVVFGNDRFKLDKSKKSDHAIGQTYVEANKLLNENEELEQEILNLMKNYEEAMENGIENEITEKFKNAVEYALT
GFKETLSTLNIHHDKFVWESEFVRSGLVRNVINRLMETGKVTEEDVYRLDLSEFGIEKKLVLARLNGTSLYSTRDVAYHM
TKMENCDFAVNLLGADHKLTGIMVNKTLALLGYNEAEIVFYEFISLPEGSMSTRQGRFISMDELFEEAKLRAREEVKKRE
VAKTEEEIEEIAKKIAVGAVRYNIVRISPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENCEPSGLVNSKNLFEYE
MAENEKIIVKLISKLPEIVEKSAEVRKPQILANYALELAQGFNKFYGNCRILKEENETVRNSRIMIVNSTKLVLENSLDL
LGIEMPGKM

Sequences:

>Translated_569_residues
MDVKKLIVVAIEKKVLDLTGKQIEIRLDEPPSINMGDYSTNIAFRLSKELKKAPKIIAEEITSSLSIPGIEKIESLNGYI
NFFMDYSVFSKETTLEINSKQENFGKSDLKNKKVILEHTSANPNGPFHIGHGRNMVIGDSLKRILNAAGYTVETQYYVND
MGRQEAIVVFGNDRFKLDKSKKSDHAIGQTYVEANKLLNENEELEQEILNLMKNYEEAMENGIENEITEKFKNAVEYALT
GFKETLSTLNIHHDKFVWESEFVRSGLVRNVINRLMETGKVTEEDVYRLDLSEFGIEKKLVLARLNGTSLYSTRDVAYHM
TKMENCDFAVNLLGADHKLTGIMVNKTLALLGYNEAEIVFYEFISLPEGSMSTRQGRFISMDELFEEAKLRAREEVKKRE
VAKTEEEIEEIAKKIAVGAVRYNIVRISPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENCEPSGLVNSKNLFEYE
MAENEKIIVKLISKLPEIVEKSAEVRKPQILANYALELAQGFNKFYGNCRILKEENETVRNSRIMIVNSTKLVLENSLDL
LGIEMPGKM
>Mature_569_residues
MDVKKLIVVAIEKKVLDLTGKQIEIRLDEPPSINMGDYSTNIAFRLSKELKKAPKIIAEEITSSLSIPGIEKIESLNGYI
NFFMDYSVFSKETTLEINSKQENFGKSDLKNKKVILEHTSANPNGPFHIGHGRNMVIGDSLKRILNAAGYTVETQYYVND
MGRQEAIVVFGNDRFKLDKSKKSDHAIGQTYVEANKLLNENEELEQEILNLMKNYEEAMENGIENEITEKFKNAVEYALT
GFKETLSTLNIHHDKFVWESEFVRSGLVRNVINRLMETGKVTEEDVYRLDLSEFGIEKKLVLARLNGTSLYSTRDVAYHM
TKMENCDFAVNLLGADHKLTGIMVNKTLALLGYNEAEIVFYEFISLPEGSMSTRQGRFISMDELFEEAKLRAREEVKKRE
VAKTEEEIEEIAKKIAVGAVRYNIVRISPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENCEPSGLVNSKNLFEYE
MAENEKIIVKLISKLPEIVEKSAEVRKPQILANYALELAQGFNKFYGNCRILKEENETVRNSRIMIVNSTKLVLENSLDL
LGIEMPGKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=585, Percent_Identity=23.4188034188034, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI197100773, Length=516, Percent_Identity=23.2558139534884, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1788184, Length=567, Percent_Identity=24.3386243386243, Blast_Score=159, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71985061, Length=588, Percent_Identity=23.2993197278912, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71985068, Length=548, Percent_Identity=23.3576642335766, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17532153, Length=489, Percent_Identity=21.6768916155419, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320548, Length=509, Percent_Identity=26.9155206286837, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321883, Length=585, Percent_Identity=24.4444444444444, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571570, Length=514, Percent_Identity=23.7354085603113, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI18859963, Length=578, Percent_Identity=23.5294117647059, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_METVS (A6UP37)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001322871.1
- ProteinModelPortal:   A6UP37
- SMR:   A6UP37
- STRING:   A6UP37
- GeneID:   5325871
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0350
- eggNOG:   arNOG04487
- HOGENOM:   HBG695395
- OMA:   NDMGRQI
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64914; Mature: 64914

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKKLIVVAIEKKVLDLTGKQIEIRLDEPPSINMGDYSTNIAFRLSKELKKAPKIIAEE
CCHHHEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHH
ITSSLSIPGIEKIESLNGYINFFMDYSVFSKETTLEINSKQENFGKSDLKNKKVILEHTS
HHHHCCCCCHHHHHHHHHHEEEEEEHHHHCCCEEEEECCCHHCCCCCCCCCCEEEEEECC
ANPNGPFHIGHGRNMVIGDSLKRILNAAGYTVETQYYVNDMGRQEAIVVFGNDRFKLDKS
CCCCCCEEECCCCCEEEHHHHHHHHHHCCCEEEEEEHCCCCCCCEEEEEECCCEEEECCC
KKSDHAIGQTYVEANKLLNENEELEQEILNLMKNYEEAMENGIENEITEKFKNAVEYALT
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GFKETLSTLNIHHDKFVWESEFVRSGLVRNVINRLMETGKVTEEDVYRLDLSEFGIEKKL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECHHHHCCCEEE
VLARLNGTSLYSTRDVAYHMTKMENCDFAVNLLGADHKLTGIMVNKTLALLGYNEAEIVF
EEEEECCCCEECHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEEEEEECCCCCEEE
YEFISLPEGSMSTRQGRFISMDELFEEAKLRAREEVKKREVAKTEEEIEEIAKKIAVGAV
EEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
RYNIVRISPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENCEPSGLVNSKNLFEYE
EEEEEEECCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
MAENEKIIVKLISKLPEIVEKSAEVRKPQILANYALELAQGFNKFYGNCRILKEENETVR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHC
NSRIMIVNSTKLVLENSLDLLGIEMPGKM
CCEEEEEECCEEEEECCCCEEEECCCCCC
>Mature Secondary Structure
MDVKKLIVVAIEKKVLDLTGKQIEIRLDEPPSINMGDYSTNIAFRLSKELKKAPKIIAEE
CCHHHEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHH
ITSSLSIPGIEKIESLNGYINFFMDYSVFSKETTLEINSKQENFGKSDLKNKKVILEHTS
HHHHCCCCCHHHHHHHHHHEEEEEEHHHHCCCEEEEECCCHHCCCCCCCCCCEEEEEECC
ANPNGPFHIGHGRNMVIGDSLKRILNAAGYTVETQYYVNDMGRQEAIVVFGNDRFKLDKS
CCCCCCEEECCCCCEEEHHHHHHHHHHCCCEEEEEEHCCCCCCCEEEEEECCCEEEECCC
KKSDHAIGQTYVEANKLLNENEELEQEILNLMKNYEEAMENGIENEITEKFKNAVEYALT
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GFKETLSTLNIHHDKFVWESEFVRSGLVRNVINRLMETGKVTEEDVYRLDLSEFGIEKKL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECHHHHCCCEEE
VLARLNGTSLYSTRDVAYHMTKMENCDFAVNLLGADHKLTGIMVNKTLALLGYNEAEIVF
EEEEECCCCEECHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEEEEEECCCCCEEE
YEFISLPEGSMSTRQGRFISMDELFEEAKLRAREEVKKREVAKTEEEIEEIAKKIAVGAV
EEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
RYNIVRISPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENCEPSGLVNSKNLFEYE
EEEEEEECCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
MAENEKIIVKLISKLPEIVEKSAEVRKPQILANYALELAQGFNKFYGNCRILKEENETVR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHC
NSRIMIVNSTKLVLENSLDLLGIEMPGKM
CCEEEEEECCEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA