| Definition | Methanococcus vannielii SB chromosome, complete genome. |
|---|---|
| Accession | NC_009634 |
| Length | 1,720,048 |
Click here to switch to the map view.
The map label for this gene is top6B [H]
Identifier: 150399069
GI number: 150399069
Start: 366456
End: 368456
Strand: Reverse
Name: top6B [H]
Synonym: Mevan_0315
Alternate gene names: 150399069
Gene position: 368456-366456 (Counterclockwise)
Preceding gene: 150399074
Following gene: 150399068
Centisome position: 21.42
GC content: 34.43
Gene sequence:
>2001_bases ATGGTTGAAGAAAATATTGAAAATTTAGTAGCTGAAAAAAGTTTATTTGATGAATTTAAAGAACACTCAATTTCTGAATT TTTCAGAAAAAATAAGCACATGCTAGGTTATAGTGGAAGATTGAGAAGCATGACCACGATTGTTCATGAACTTGTAACAA ACAGCATGGACGCATGTGAAGAATCAGAAATATTGCCAGAAATTCTAGTTGAAGTTAAAAAAGTAGGTTCTGAAACATTT ACAGTTATAATTGAGGATAATGGGCCAGGAATTCCTCCAGAATATGTTTCAAAGGTATTTGGTAAGATGCTTGCAGGTTC AAAGCTTCATAGGCTGGTTCAGTCAAGAGGTCAGCAAGGTATTGGTGCAGCGGGAGTTTTATTATTTTCCCAAATGACTA CTGGAAGGCCTTTAAAAATTACAACTTCCACTGGAACTGGAAAAATCCATGAAATGGAAATTAAAATGAGCATTGAAAAA AACGAAGGGGATATTGTAGCCCATAAAATAAGGGAGGGCTATTTTAGGGGAACACGCGTAGAAGGTGAATTTAAGGAAGT AACCTATAATAGAAGAGAGCAAGGGCCGTACGAATACCTTAGAAGGATAAGTTTATCGACACCTCATGCCAAAATTACCC TTATAGATCCTGAAGAAACAACAATATTTGAAAGAACAGTAACTGTAATTCCTGAAAGGCCGGAAGTAATGAAACCACAC CCTTATGGATTAACAACTGATGAATTACTCCATATTTCAAGAAAAACGGATTCTTCAAGAATTTCAAGCATGCTAAATAG TGAACTTTCAAGAGTTACAATGAAACGAATAAGGGATCTTGAAGACTATGTTTTAAGGGATAAACTTTTAGAAAATTATC GAAAGAGTGTTTTTTGGGATACCATTGTTGGATGTTACCTGAATTTTAATTTTACTAAATATTTTGAGATATATGGCCAC TATTTGGATAAAAAAGAAATAGAAGACGTAAAAATGTTAATTAATGGCCTTCCTGAGGGATTATCTGAACTTAAAACGTA CTGTTTAAAGTATCTGGTTGTCGAATACCTGATTCAAAAATTGGATGACGAACAGCTAAAAGAAAATAAGAACCATTTTA AGAAAAAACCTGAAAATTTCATGGAGTTTGCAGAGAAAAATTATTTAAATGCATCGCTTCTTGAAGAATTTAGGCGAAAG CTAAAAACAATTACAAAATCGCCTGAAGATTTTGTAAAAGCGCTTACCGACCTTGGAATGGTTTCTGAAGAAGAGCTTGA AAAATACCGAAAATCAATAAAAGACCTATTGAAAAAAACCCCCCGAGAAATGACGTGGTCGGATTCAGAAATTATTGTAA ATGTTTTACAGGATATGGACTTTATGGCTCCATCCACAATTGGACTAAGGCCAATTGGTGAAGAAAATATTGAAAAATCA CTTGAAACACTAACTCCAGAATTTTTGAAAACCCTTACGCGAAAACCAAAAACATATAAAGGTGGAATTCCATTTGCAGT CGAAGTTGGGCTTGCATATGGGGGTAATGCCGGGAGAAGTGGCGAAGACTCCAAAAAAATGGAAATAATGAGATTTTCAA ATCACGTACCATTATTATTTGATACATCAGGCTGCGGGCTTACAAACGCTGTTAAAAGTGTAAATTGGAAAAGATATGGA CTTAGAAGTGATGAAGATGCCCCTGTAACGATATTTGTGAATCTCATTTCAACACATATCCCTTATACATCTGCTGGAAA ACAAGCAATCGCAACAGGCTCAGAAGAAAACGAAGAAATTTTTAATGAAGTAAGGCAATCATTAATGATATGTGCAAGGG AGCTTGATACACATATTTCAAGGGTAAGGCGTGAAAAAGAAGAAGAACAAAAGAAAAAATATGTAATAAAATATGCATAT ATATTTGCAGAGGGACTTTCAAGCATTACTGGACGGTCGAAAGAGGAGATAGAGTCAAATATAATTAATCTTTTAAGATA A
Upstream 100 bases:
>100_bases TATCTACTTGGTAAAAAACTTTGATTTTTGTGTTTTACCATTCATTATTACTCATATAGTTTTATTTTATCCAGTTTATA TTTTGGCTGTGGTGATTTTA
Downstream 100 bases:
>100_bases ATTAACTACTTTTACTATTTTTACTATTTTTACATTTTAATTATTTTACTATTTTTTCTATATTGCCATTTAAGTTTAAT TTAGCTACTCGATACTTTAA
Product: DNA topoisomerase VI subunit B
Products: NA
Alternate protein names: Type II DNA topoisomerase VI subunit B; TopoVI-B [H]
Number of amino acids: Translated: 666; Mature: 666
Protein sequence:
>666_residues MVEENIENLVAEKSLFDEFKEHSISEFFRKNKHMLGYSGRLRSMTTIVHELVTNSMDACEESEILPEILVEVKKVGSETF TVIIEDNGPGIPPEYVSKVFGKMLAGSKLHRLVQSRGQQGIGAAGVLLFSQMTTGRPLKITTSTGTGKIHEMEIKMSIEK NEGDIVAHKIREGYFRGTRVEGEFKEVTYNRREQGPYEYLRRISLSTPHAKITLIDPEETTIFERTVTVIPERPEVMKPH PYGLTTDELLHISRKTDSSRISSMLNSELSRVTMKRIRDLEDYVLRDKLLENYRKSVFWDTIVGCYLNFNFTKYFEIYGH YLDKKEIEDVKMLINGLPEGLSELKTYCLKYLVVEYLIQKLDDEQLKENKNHFKKKPENFMEFAEKNYLNASLLEEFRRK LKTITKSPEDFVKALTDLGMVSEEELEKYRKSIKDLLKKTPREMTWSDSEIIVNVLQDMDFMAPSTIGLRPIGEENIEKS LETLTPEFLKTLTRKPKTYKGGIPFAVEVGLAYGGNAGRSGEDSKKMEIMRFSNHVPLLFDTSGCGLTNAVKSVNWKRYG LRSDEDAPVTIFVNLISTHIPYTSAGKQAIATGSEENEEIFNEVRQSLMICARELDTHISRVRREKEEEQKKKYVIKYAY IFAEGLSSITGRSKEEIESNIINLLR
Sequences:
>Translated_666_residues MVEENIENLVAEKSLFDEFKEHSISEFFRKNKHMLGYSGRLRSMTTIVHELVTNSMDACEESEILPEILVEVKKVGSETF TVIIEDNGPGIPPEYVSKVFGKMLAGSKLHRLVQSRGQQGIGAAGVLLFSQMTTGRPLKITTSTGTGKIHEMEIKMSIEK NEGDIVAHKIREGYFRGTRVEGEFKEVTYNRREQGPYEYLRRISLSTPHAKITLIDPEETTIFERTVTVIPERPEVMKPH PYGLTTDELLHISRKTDSSRISSMLNSELSRVTMKRIRDLEDYVLRDKLLENYRKSVFWDTIVGCYLNFNFTKYFEIYGH YLDKKEIEDVKMLINGLPEGLSELKTYCLKYLVVEYLIQKLDDEQLKENKNHFKKKPENFMEFAEKNYLNASLLEEFRRK LKTITKSPEDFVKALTDLGMVSEEELEKYRKSIKDLLKKTPREMTWSDSEIIVNVLQDMDFMAPSTIGLRPIGEENIEKS LETLTPEFLKTLTRKPKTYKGGIPFAVEVGLAYGGNAGRSGEDSKKMEIMRFSNHVPLLFDTSGCGLTNAVKSVNWKRYG LRSDEDAPVTIFVNLISTHIPYTSAGKQAIATGSEENEEIFNEVRQSLMICARELDTHISRVRREKEEEQKKKYVIKYAY IFAEGLSSITGRSKEEIESNIINLLR >Mature_666_residues MVEENIENLVAEKSLFDEFKEHSISEFFRKNKHMLGYSGRLRSMTTIVHELVTNSMDACEESEILPEILVEVKKVGSETF TVIIEDNGPGIPPEYVSKVFGKMLAGSKLHRLVQSRGQQGIGAAGVLLFSQMTTGRPLKITTSTGTGKIHEMEIKMSIEK NEGDIVAHKIREGYFRGTRVEGEFKEVTYNRREQGPYEYLRRISLSTPHAKITLIDPEETTIFERTVTVIPERPEVMKPH PYGLTTDELLHISRKTDSSRISSMLNSELSRVTMKRIRDLEDYVLRDKLLENYRKSVFWDTIVGCYLNFNFTKYFEIYGH YLDKKEIEDVKMLINGLPEGLSELKTYCLKYLVVEYLIQKLDDEQLKENKNHFKKKPENFMEFAEKNYLNASLLEEFRRK LKTITKSPEDFVKALTDLGMVSEEELEKYRKSIKDLLKKTPREMTWSDSEIIVNVLQDMDFMAPSTIGLRPIGEENIEKS LETLTPEFLKTLTRKPKTYKGGIPFAVEVGLAYGGNAGRSGEDSKKMEIMRFSNHVPLLFDTSGCGLTNAVKSVNWKRYG LRSDEDAPVTIFVNLISTHIPYTSAGKQAIATGSEENEEIFNEVRQSLMICARELDTHISRVRREKEEEQKKKYVIKYAY IFAEGLSSITGRSKEEIESNIINLLR
Specific function: Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP [H]
COG id: COG1389
COG function: function code L; DNA topoisomerase VI, subunit B
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TOP6B family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR005734 - InterPro: IPR015320 - ProDom: PD013790 [H]
Pfam domain/function: PF02518 HATPase_c; PF09239 Topo-VIb_trans [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 76515; Mature: 76515
Theoretical pI: Translated: 6.65; Mature: 6.65
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVEENIENLVAEKSLFDEFKEHSISEFFRKNKHMLGYSGRLRSMTTIVHELVTNSMDACE CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH ESEILPEILVEVKKVGSETFTVIIEDNGPGIPPEYVSKVFGKMLAGSKLHRLVQSRGQQG HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC IGAAGVLLFSQMTTGRPLKITTSTGTGKIHEMEIKMSIEKNEGDIVAHKIREGYFRGTRV CCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCC EGEFKEVTYNRREQGPYEYLRRISLSTPHAKITLIDPEETTIFERTVTVIPERPEVMKPH CCHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCC PYGLTTDELLHISRKTDSSRISSMLNSELSRVTMKRIRDLEDYVLRDKLLENYRKSVFWD CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TIVGCYLNFNFTKYFEIYGHYLDKKEIEDVKMLINGLPEGLSELKTYCLKYLVVEYLIQK HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH LDDEQLKENKNHFKKKPENFMEFAEKNYLNASLLEEFRRKLKTITKSPEDFVKALTDLGM CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC VSEEELEKYRKSIKDLLKKTPREMTWSDSEIIVNVLQDMDFMAPSTIGLRPIGEENIEKS CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH LETLTPEFLKTLTRKPKTYKGGIPFAVEVGLAYGGNAGRSGEDSKKMEIMRFSNHVPLLF HHHCCHHHHHHHHCCCCCCCCCCCEEEEEECEECCCCCCCCCCHHHHHHHHHCCCCCEEE DTSGCGLTNAVKSVNWKRYGLRSDEDAPVTIFVNLISTHIPYTSAGKQAIATGSEENEEI ECCCCCHHHHHHHCCCHHCCCCCCCCCCEEEEHHHHHHHCCCCCCCCHHHCCCCCCCHHH FNEVRQSLMICARELDTHISRVRREKEEEQKKKYVIKYAYIFAEGLSSITGRSKEEIESN HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH IINLLR HHHHCC >Mature Secondary Structure MVEENIENLVAEKSLFDEFKEHSISEFFRKNKHMLGYSGRLRSMTTIVHELVTNSMDACE CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH ESEILPEILVEVKKVGSETFTVIIEDNGPGIPPEYVSKVFGKMLAGSKLHRLVQSRGQQG HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC IGAAGVLLFSQMTTGRPLKITTSTGTGKIHEMEIKMSIEKNEGDIVAHKIREGYFRGTRV CCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCC EGEFKEVTYNRREQGPYEYLRRISLSTPHAKITLIDPEETTIFERTVTVIPERPEVMKPH CCHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCC PYGLTTDELLHISRKTDSSRISSMLNSELSRVTMKRIRDLEDYVLRDKLLENYRKSVFWD CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TIVGCYLNFNFTKYFEIYGHYLDKKEIEDVKMLINGLPEGLSELKTYCLKYLVVEYLIQK HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH LDDEQLKENKNHFKKKPENFMEFAEKNYLNASLLEEFRRKLKTITKSPEDFVKALTDLGM CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC VSEEELEKYRKSIKDLLKKTPREMTWSDSEIIVNVLQDMDFMAPSTIGLRPIGEENIEKS CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH LETLTPEFLKTLTRKPKTYKGGIPFAVEVGLAYGGNAGRSGEDSKKMEIMRFSNHVPLLF HHHCCHHHHHHHHCCCCCCCCCCCEEEEEECEECCCCCCCCCCHHHHHHHHHCCCCCEEE DTSGCGLTNAVKSVNWKRYGLRSDEDAPVTIFVNLISTHIPYTSAGKQAIATGSEENEEI ECCCCCHHHHHHHCCCHHCCCCCCCCCCEEEEHHHHHHHCCCCCCCCHHHCCCCCCCHHH FNEVRQSLMICARELDTHISRVRREKEEEQKKKYVIKYAYIFAEGLSSITGRSKEEIESN HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH IINLLR HHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]