Click here to switch to the map view.

The map label for this gene is 150399021

Identifier: 150399021

GI number: 150399021

Start: 313108

End: 314931

Strand: Reverse

Name: 150399021

Synonym: Mevan_0267

Alternate gene names: NA

Gene position: 314931-313108 (Counterclockwise)

Preceding gene: 150399023

Following gene: 150399020

Centisome position: 18.31

GC content: 36.84

Gene sequence:

>1824_bases
ATGGTCGACAAAACTACGGCGCTTATGGAAACAACGAAAGAAGAAATTATCAGGTCAGTTCAAACATTTCGGAAGTTAAA
GAACGATAATTGTGGGAAATCAACTGCAAGTGATACAATCATTTACGTTCTCGATAATTATCAAGATGTAAATTTTACCG
TTGATGGGCTAAAACAACTTCTAATCGGTGCGAAAATGAACCGCAGTACCGTTAGTAAGTACATTGGAAAACTAATGGAT
ACAAACATAATTTACGAAGATCCATTTGGCTATTTACGTAAGTCCGGAACCAGTATATCTGACATTTCGAAAAAACTGTT
AGATAACCACATTAAACAGATGACAAACGGTAAACCCGTGATCGTTGATTTTCAAAAGGAATATGGTGCGGACACATTTC
TGTTAGATAAACTTGATAGCAACCCCAATGACGTTTTTAGAATGTTTTCGGAAGCATATGCTGAAGCTTACACGCCATTA
GCTAAAGATAACGTGGCATATTACAATGTTGCAATCAAAAACCTACCAAATAAGTACCGATGTAAAATTGGGAACTTAAA
TTCAACTTCGATCGGTAAAATTGTCGAATTTGAGGGTATCGTATTGTCAGCGTCAGTAAATAAAGTCATGGTGAAAAAAG
CAGTATATTCATGCGCTTGTGGTAAAAAAGAAGAATATGCACTAGATAATGTATTTGAAAAGGATGTTTCTGACAAAGTA
AAATGTAACTGCGGAAAATACATGGTTTTTGATGAAAATAACTCTAAATATGTAGATATACAGGAACTAACGTTACAGCA
ACCAGTAGAATCGACGGATAACCCACAAGAACCACCAAACGATATTACGGTATTTTTTGAGACCACTTCCAAAATATGGA
ACGGTAAGGTAAACGTTATTGGAATTCCGTTCAAAAAGAAACAGAAAAACGCTCCAGTATACGATATTTACATTTACGCT
AAACACGTCGTTTCAGAAGAAAATGCTTCAAAACGCCCTTTAGATGAAACCAAAATAGCCCATATGAAGCATATCGTGGA
GTACTGTAACAATAATAACATCGATTTACTCGATAAGCTCTCTGAATTACTTATTCCAACAATCCACGGTTACGAAATCA
TACGAAAAGCGATATTACTTCAACAAATCAAAGGATCTGTTGGTTTAAACCGTAATAATATCCACATACTGCTGGTTTCA
GATCCCGGATTAGGTAAATCGGAAATCCTTCGTAGAGTTTCAAAATTTCCGAAAAACACGTATGGCTCACTTGCTGGAAC
TTCGGGTGTCGGATTAACGGCTTCTATAGACTATGTAAAAAGTTTGATTGGTGATAGTGGCCGGGTATCTAAACCAGGTT
TACTGGTCGCTAAAAATGGTGGAACCGTATCCTTAGATGAAGTAACCGTAAACGACATGTCAATTCACCTTTTAGAGGCA
ATGGAATCGCAGACCATACACATTGCAAAGGCAGGTGCAACTTTATGTTTTCCTGCTGAAGTTGCAATTCTTGCTGCGTG
TAACCCCAAAAGCGGTCGACAGGATAAATCCAAATGGTTAATTGAACAGATTGAGTTAAGTGAACCGGTTATTGATCGAT
TCGACCTGATATTCGACATGAATCCTGAGAATAACCGCGAATCAGATGAAGAAATAGCTCAAAAAATCATTAAAAATTAT
AACTACGTTTCACCAATGGTCAATGGCGATACTGCCGTAACTACCCGTGTAGGCGAATATATTCTCGACTACTCATTTTT
GATGGATTTTATCGAATATACTAGGGCTTTGAACGTTAAAATTCCCGAATCAGTTGAAAATTAA

Upstream 100 bases:

>100_bases
CGATGGAAAGCTTGTGTGATATTTATATAGTACGCGATTCAGTGATATTTTCGGAAATAAACACGACAAATATACTAAAA
ACTGATGAACGGGGCATTTA

Downstream 100 bases:

>100_bases
TAGTTGACTATTATGTTCGAAGTACTGAATACCGTAAAAGACTAAACCCAAGGTTGGTTGAAAATAAGACGTCGGCCCGG
TTGGTTGAAACGTTGATCAG

Product: MCM family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MVDKTTALMETTKEEIIRSVQTFRKLKNDNCGKSTASDTIIYVLDNYQDVNFTVDGLKQLLIGAKMNRSTVSKYIGKLMD
TNIIYEDPFGYLRKSGTSISDISKKLLDNHIKQMTNGKPVIVDFQKEYGADTFLLDKLDSNPNDVFRMFSEAYAEAYTPL
AKDNVAYYNVAIKNLPNKYRCKIGNLNSTSIGKIVEFEGIVLSASVNKVMVKKAVYSCACGKKEEYALDNVFEKDVSDKV
KCNCGKYMVFDENNSKYVDIQELTLQQPVESTDNPQEPPNDITVFFETTSKIWNGKVNVIGIPFKKKQKNAPVYDIYIYA
KHVVSEENASKRPLDETKIAHMKHIVEYCNNNNIDLLDKLSELLIPTIHGYEIIRKAILLQQIKGSVGLNRNNIHILLVS
DPGLGKSEILRRVSKFPKNTYGSLAGTSGVGLTASIDYVKSLIGDSGRVSKPGLLVAKNGGTVSLDEVTVNDMSIHLLEA
MESQTIHIAKAGATLCFPAEVAILAACNPKSGRQDKSKWLIEQIELSEPVIDRFDLIFDMNPENNRESDEEIAQKIIKNY
NYVSPMVNGDTAVTTRVGEYILDYSFLMDFIEYTRALNVKIPESVEN

Sequences:

>Translated_607_residues
MVDKTTALMETTKEEIIRSVQTFRKLKNDNCGKSTASDTIIYVLDNYQDVNFTVDGLKQLLIGAKMNRSTVSKYIGKLMD
TNIIYEDPFGYLRKSGTSISDISKKLLDNHIKQMTNGKPVIVDFQKEYGADTFLLDKLDSNPNDVFRMFSEAYAEAYTPL
AKDNVAYYNVAIKNLPNKYRCKIGNLNSTSIGKIVEFEGIVLSASVNKVMVKKAVYSCACGKKEEYALDNVFEKDVSDKV
KCNCGKYMVFDENNSKYVDIQELTLQQPVESTDNPQEPPNDITVFFETTSKIWNGKVNVIGIPFKKKQKNAPVYDIYIYA
KHVVSEENASKRPLDETKIAHMKHIVEYCNNNNIDLLDKLSELLIPTIHGYEIIRKAILLQQIKGSVGLNRNNIHILLVS
DPGLGKSEILRRVSKFPKNTYGSLAGTSGVGLTASIDYVKSLIGDSGRVSKPGLLVAKNGGTVSLDEVTVNDMSIHLLEA
MESQTIHIAKAGATLCFPAEVAILAACNPKSGRQDKSKWLIEQIELSEPVIDRFDLIFDMNPENNRESDEEIAQKIIKNY
NYVSPMVNGDTAVTTRVGEYILDYSFLMDFIEYTRALNVKIPESVEN
>Mature_607_residues
MVDKTTALMETTKEEIIRSVQTFRKLKNDNCGKSTASDTIIYVLDNYQDVNFTVDGLKQLLIGAKMNRSTVSKYIGKLMD
TNIIYEDPFGYLRKSGTSISDISKKLLDNHIKQMTNGKPVIVDFQKEYGADTFLLDKLDSNPNDVFRMFSEAYAEAYTPL
AKDNVAYYNVAIKNLPNKYRCKIGNLNSTSIGKIVEFEGIVLSASVNKVMVKKAVYSCACGKKEEYALDNVFEKDVSDKV
KCNCGKYMVFDENNSKYVDIQELTLQQPVESTDNPQEPPNDITVFFETTSKIWNGKVNVIGIPFKKKQKNAPVYDIYIYA
KHVVSEENASKRPLDETKIAHMKHIVEYCNNNNIDLLDKLSELLIPTIHGYEIIRKAILLQQIKGSVGLNRNNIHILLVS
DPGLGKSEILRRVSKFPKNTYGSLAGTSGVGLTASIDYVKSLIGDSGRVSKPGLLVAKNGGTVSLDEVTVNDMSIHLLEA
MESQTIHIAKAGATLCFPAEVAILAACNPKSGRQDKSKWLIEQIELSEPVIDRFDLIFDMNPENNRESDEEIAQKIIKNY
NYVSPMVNGDTAVTTRVGEYILDYSFLMDFIEYTRALNVKIPESVEN

Specific function: Unknown

COG id: COG1241

COG function: function code L; Predicted ATPase involved in replication control, Cdc46/Mcm family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MCM domain [H]

Homologues:

Organism=Homo sapiens, GI33469919, Length=499, Percent_Identity=27.6553106212425, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI33469917, Length=499, Percent_Identity=27.6553106212425, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI6631095, Length=412, Percent_Identity=29.3689320388349, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI7427519, Length=478, Percent_Identity=25.9414225941423, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI33469968, Length=415, Percent_Identity=30.1204819277108, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI23510448, Length=588, Percent_Identity=25.5102040816327, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI33469922, Length=393, Percent_Identity=28.498727735369, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI33356547, Length=279, Percent_Identity=30.8243727598566, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI33469924, Length=397, Percent_Identity=26.9521410579345, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI19923727, Length=206, Percent_Identity=33.9805825242718, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562702, Length=401, Percent_Identity=28.927680798005, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17562700, Length=430, Percent_Identity=27.6744186046512, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508417, Length=449, Percent_Identity=26.7260579064588, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71997752, Length=498, Percent_Identity=25.5020080321285, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17554306, Length=512, Percent_Identity=25.390625, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71997563, Length=184, Percent_Identity=36.4130434782609, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71997571, Length=187, Percent_Identity=35.2941176470588, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325276, Length=470, Percent_Identity=26.5957446808511, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323304, Length=526, Percent_Identity=27.3764258555133, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320803, Length=422, Percent_Identity=27.9620853080569, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6321237, Length=212, Percent_Identity=35.377358490566, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319448, Length=464, Percent_Identity=26.0775862068966, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319679, Length=460, Percent_Identity=25.4347826086956, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17137242, Length=489, Percent_Identity=27.8118609406953, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645774, Length=535, Percent_Identity=25.981308411215, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI17530827, Length=248, Percent_Identity=35.8870967741936, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24639835, Length=412, Percent_Identity=27.4271844660194, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647617, Length=471, Percent_Identity=26.963906581741, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17137132, Length=275, Percent_Identity=29.8181818181818, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647251, Length=181, Percent_Identity=28.7292817679558, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001208
- InterPro:   IPR018525
- InterPro:   IPR008047
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00493 MCM [H]

EC number: NA

Molecular weight: Translated: 67988; Mature: 67988

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00018 EF_HAND_1 ; PS50051 MCM_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKTTALMETTKEEIIRSVQTFRKLKNDNCGKSTASDTIIYVLDNYQDVNFTVDGLKQL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHH
LIGAKMNRSTVSKYIGKLMDTNIIYEDPFGYLRKSGTSISDISKKLLDNHIKQMTNGKPV
HHCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
IVDFQKEYGADTFLLDKLDSNPNDVFRMFSEAYAEAYTPLAKDNVAYYNVAIKNLPNKYR
EEEEHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCE
CKIGNLNSTSIGKIVEFEGIVLSASVNKVMVKKAVYSCACGKKEEYALDNVFEKDVSDKV
EEECCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCE
KCNCGKYMVFDENNSKYVDIQELTLQQPVESTDNPQEPPNDITVFFETTSKIWNGKVNVI
EECCCCEEEEECCCCCEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHCCCEEEE
GIPFKKKQKNAPVYDIYIYAKHVVSEENASKRPLDETKIAHMKHIVEYCNNNNIDLLDKL
ECCCHHCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SELLIPTIHGYEIIRKAILLQQIKGSVGLNRNNIHILLVSDPGLGKSEILRRVSKFPKNT
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCC
YGSLAGTSGVGLTASIDYVKSLIGDSGRVSKPGLLVAKNGGTVSLDEVTVNDMSIHLLEA
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEECCHHHHHHHH
MESQTIHIAKAGATLCFPAEVAILAACNPKSGRQDKSKWLIEQIELSEPVIDRFDLIFDM
HCCCEEEEEECCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHEEEEEEC
NPENNRESDEEIAQKIIKNYNYVSPMVNGDTAVTTRVGEYILDYSFLMDFIEYTRALNVK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IPESVEN
CCHHCCC
>Mature Secondary Structure
MVDKTTALMETTKEEIIRSVQTFRKLKNDNCGKSTASDTIIYVLDNYQDVNFTVDGLKQL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHH
LIGAKMNRSTVSKYIGKLMDTNIIYEDPFGYLRKSGTSISDISKKLLDNHIKQMTNGKPV
HHCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
IVDFQKEYGADTFLLDKLDSNPNDVFRMFSEAYAEAYTPLAKDNVAYYNVAIKNLPNKYR
EEEEHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCE
CKIGNLNSTSIGKIVEFEGIVLSASVNKVMVKKAVYSCACGKKEEYALDNVFEKDVSDKV
EEECCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCE
KCNCGKYMVFDENNSKYVDIQELTLQQPVESTDNPQEPPNDITVFFETTSKIWNGKVNVI
EECCCCEEEEECCCCCEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHCCCEEEE
GIPFKKKQKNAPVYDIYIYAKHVVSEENASKRPLDETKIAHMKHIVEYCNNNNIDLLDKL
ECCCHHCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SELLIPTIHGYEIIRKAILLQQIKGSVGLNRNNIHILLVSDPGLGKSEILRRVSKFPKNT
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCC
YGSLAGTSGVGLTASIDYVKSLIGDSGRVSKPGLLVAKNGGTVSLDEVTVNDMSIHLLEA
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEECCHHHHHHHH
MESQTIHIAKAGATLCFPAEVAILAACNPKSGRQDKSKWLIEQIELSEPVIDRFDLIFDM
HCCCEEEEEECCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHEEEEEEC
NPENNRESDEEIAQKIIKNYNYVSPMVNGDTAVTTRVGEYILDYSFLMDFIEYTRALNVK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IPESVEN
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]