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The map label for this gene is cysS [H]

Identifier: 150398926

GI number: 150398926

Start: 200523

End: 201902

Strand: Reverse

Name: cysS [H]

Synonym: Mevan_0170

Alternate gene names: 150398926

Gene position: 201902-200523 (Counterclockwise)

Preceding gene: 150398932

Following gene: 150398925

Centisome position: 11.74

GC content: 28.99

Gene sequence:

>1380_bases
ATGTTACAAATTTATAATACCTTATCAAAAAAAGAAGAATTATTCCTTCCTAATCATCAAAATATTGTTAAATTATTTGT
TTGCGGGCCAACTACCTATGCAGAATCCCATATTGGACATGCACGAACATATATTGCATTTGATGCTATCGTTCGTTATT
TAAAATATCTTGGATATACCGTATTTTATCTTCAAAATATTACAGATATTGACGATAAAATAATAGATAAAGCAAAAATA
CAATCAAAAAATCCGGATTTATTATCAAAACATTATGAAAAAAAATATCTTGAAGATATGGAGAATTTGGGCGTCAATAA
CGTAAATTTCTATGCACGGGCAACTGAACACACATTTGAAATAATAAATCAAGTTAAAATTTTGATTGAAAAAGGTTTTG
CATACGAAACTGAAAACGGTGTTTATTTTGAAGTATCTAAATTTCAAGAGTTTGGAAAATTATCGAATCAAAATATTGAA
GAATTAAATGTTCACCGTGTAAATCCAGATGGGCTAAAAAAAGATGTAAAAGACTTTGTACTTTGGAAAAAAGTCAGTGA
AAAACCATGCTGGGATTCCCCTTGGGGTTTTGGGCGACCTGGGTGGCATATTGAAGATACTGCAATTACTGAAAAATATT
TCGGGCCAAAATATGATATTCATGGTGGAGGGCTTGATTTAATATTCCCCCACCATGAAGCAGAAATCGCCCAAATGGAG
TCAATTTCTGGCGAAAAACCAATGGTGAAATACTGGATGCATACTGGATTTTTAAATGTAAATGGGACTAAAATGTCGAA
ATCTCTTAGTAACTTTATTACTATTAAAGAAATTTTAGAAAAGTACAATGCCTTGGAATTTAGGTTCTTTGTTTTATCGA
CACATTATCGGAGTCCAATAGATTTTAGTTCAGAGAACCTTGAGGCATCAAAGAAAAGTTTTGAAAGAATAACAAATTTT
ATCAAATCTACAGAATTTTTTATCCCAATTCTTGAAATTGAACATGAAAATGACGATTTAGTTGAACAAAATATTAAATT
TACGAAGGAAAAGTTTTTTGATGCAATGAATAATGATTTTAATACTCCTTTAGCAATTTCGGCAATTTTTGGATATGTAC
GATTTATTAATAAGCACTTAAACGACAAAAATATATCTAAAAAATCGCTTTTAAAATCAAGCGAGCTAATTTTTGAACTT
ATGCAAGTTCTTGGGTTTGAGATAAAAACTAACTTAAAAAATGATAAAAATGCTGAAGAATTGTTAGATTTAATTTTAAA
CGTTAGATCAAAACTTAGAGAAAAAAAAGAATGGGAAATTTCAGATTATATCAGAAATAGGCTAAATGAAATAAACATAA
AAATAGATGACATCAAATAA

Upstream 100 bases:

>100_bases
CAAATTGGGCACATCGCTTAAAATCGGGATATTTTATTCTAAATTCCAATTTTTGGTTTTAAATTCCCTAAAACTATAAA
AAAGTACTGATGTGATAATT

Downstream 100 bases:

>100_bases
GACCAAGTGATTAATATGGAATGCAAAAAATGTAAAAGTCCGTCTATATATCATCAAAAACATTCTGGAAAACACTTCTG
TAAGGAATGTTTTATAAACG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLQIYNTLSKKEELFLPNHQNIVKLFVCGPTTYAESHIGHARTYIAFDAIVRYLKYLGYTVFYLQNITDIDDKIIDKAKI
QSKNPDLLSKHYEKKYLEDMENLGVNNVNFYARATEHTFEIINQVKILIEKGFAYETENGVYFEVSKFQEFGKLSNQNIE
ELNVHRVNPDGLKKDVKDFVLWKKVSEKPCWDSPWGFGRPGWHIEDTAITEKYFGPKYDIHGGGLDLIFPHHEAEIAQME
SISGEKPMVKYWMHTGFLNVNGTKMSKSLSNFITIKEILEKYNALEFRFFVLSTHYRSPIDFSSENLEASKKSFERITNF
IKSTEFFIPILEIEHENDDLVEQNIKFTKEKFFDAMNNDFNTPLAISAIFGYVRFINKHLNDKNISKKSLLKSSELIFEL
MQVLGFEIKTNLKNDKNAEELLDLILNVRSKLREKKEWEISDYIRNRLNEINIKIDDIK

Sequences:

>Translated_459_residues
MLQIYNTLSKKEELFLPNHQNIVKLFVCGPTTYAESHIGHARTYIAFDAIVRYLKYLGYTVFYLQNITDIDDKIIDKAKI
QSKNPDLLSKHYEKKYLEDMENLGVNNVNFYARATEHTFEIINQVKILIEKGFAYETENGVYFEVSKFQEFGKLSNQNIE
ELNVHRVNPDGLKKDVKDFVLWKKVSEKPCWDSPWGFGRPGWHIEDTAITEKYFGPKYDIHGGGLDLIFPHHEAEIAQME
SISGEKPMVKYWMHTGFLNVNGTKMSKSLSNFITIKEILEKYNALEFRFFVLSTHYRSPIDFSSENLEASKKSFERITNF
IKSTEFFIPILEIEHENDDLVEQNIKFTKEKFFDAMNNDFNTPLAISAIFGYVRFINKHLNDKNISKKSLLKSSELIFEL
MQVLGFEIKTNLKNDKNAEELLDLILNVRSKLREKKEWEISDYIRNRLNEINIKIDDIK
>Mature_459_residues
MLQIYNTLSKKEELFLPNHQNIVKLFVCGPTTYAESHIGHARTYIAFDAIVRYLKYLGYTVFYLQNITDIDDKIIDKAKI
QSKNPDLLSKHYEKKYLEDMENLGVNNVNFYARATEHTFEIINQVKILIEKGFAYETENGVYFEVSKFQEFGKLSNQNIE
ELNVHRVNPDGLKKDVKDFVLWKKVSEKPCWDSPWGFGRPGWHIEDTAITEKYFGPKYDIHGGGLDLIFPHHEAEIAQME
SISGEKPMVKYWMHTGFLNVNGTKMSKSLSNFITIKEILEKYNALEFRFFVLSTHYRSPIDFSSENLEASKKSFERITNF
IKSTEFFIPILEIEHENDDLVEQNIKFTKEKFFDAMNNDFNTPLAISAIFGYVRFINKHLNDKNISKKSLLKSSELIFEL
MQVLGFEIKTNLKNDKNAEELLDLILNVRSKLREKKEWEISDYIRNRLNEINIKIDDIK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=36.6925064599483, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI303304987, Length=423, Percent_Identity=31.2056737588652, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI21269877, Length=423, Percent_Identity=31.2056737588652, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI62240992, Length=423, Percent_Identity=31.2056737588652, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI10835051, Length=423, Percent_Identity=31.2056737588652, Blast_Score=181, Evalue=9e-46,
Organism=Escherichia coli, GI1786737, Length=464, Percent_Identity=38.1465517241379, Blast_Score=312, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17509795, Length=264, Percent_Identity=39.3939393939394, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17509797, Length=264, Percent_Identity=39.3939393939394, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=453, Percent_Identity=30.9050772626932, Blast_Score=179, Evalue=7e-46,
Organism=Drosophila melanogaster, GI19922218, Length=497, Percent_Identity=32.9979879275654, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI19922364, Length=350, Percent_Identity=31.1428571428571, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53808; Mature: 53808

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQIYNTLSKKEELFLPNHQNIVKLFVCGPTTYAESHIGHARTYIAFDAIVRYLKYLGYT
CCCHHHHHCCHHHCCCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFYLQNITDIDDKIIDKAKIQSKNPDLLSKHYEKKYLEDMENLGVNNVNFYARATEHTFE
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHH
IINQVKILIEKGFAYETENGVYFEVSKFQEFGKLSNQNIEELNVHRVNPDGLKKDVKDFV
HHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHCCCCCHHHCEEEECCHHHHHHHHHHHH
LWKKVSEKPCWDSPWGFGRPGWHIEDTAITEKYFGPKYDIHGGGLDLIFPHHEAEIAQME
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHH
SISGEKPMVKYWMHTGFLNVNGTKMSKSLSNFITIKEILEKYNALEFRFFVLSTHYRSPI
HCCCCCCHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
DFSSENLEASKKSFERITNFIKSTEFFIPILEIEHENDDLVEQNIKFTKEKFFDAMNNDF
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
NTPLAISAIFGYVRFINKHLNDKNISKKSLLKSSELIFELMQVLGFEIKTNLKNDKNAEE
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHH
LLDLILNVRSKLREKKEWEISDYIRNRLNEINIKIDDIK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEEECCC
>Mature Secondary Structure
MLQIYNTLSKKEELFLPNHQNIVKLFVCGPTTYAESHIGHARTYIAFDAIVRYLKYLGYT
CCCHHHHHCCHHHCCCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFYLQNITDIDDKIIDKAKIQSKNPDLLSKHYEKKYLEDMENLGVNNVNFYARATEHTFE
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHH
IINQVKILIEKGFAYETENGVYFEVSKFQEFGKLSNQNIEELNVHRVNPDGLKKDVKDFV
HHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHCCCCCHHHCEEEECCHHHHHHHHHHHH
LWKKVSEKPCWDSPWGFGRPGWHIEDTAITEKYFGPKYDIHGGGLDLIFPHHEAEIAQME
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHH
SISGEKPMVKYWMHTGFLNVNGTKMSKSLSNFITIKEILEKYNALEFRFFVLSTHYRSPI
HCCCCCCHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
DFSSENLEASKKSFERITNFIKSTEFFIPILEIEHENDDLVEQNIKFTKEKFFDAMNNDF
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
NTPLAISAIFGYVRFINKHLNDKNISKKSLLKSSELIFELMQVLGFEIKTNLKNDKNAEE
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHH
LLDLILNVRSKLREKKEWEISDYIRNRLNEINIKIDDIK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA