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The map label for this gene is argJ

Identifier: 150398783

GI number: 150398783

Start: 19823

End: 21049

Strand: Reverse

Name: argJ

Synonym: Mevan_0023

Alternate gene names: 150398783

Gene position: 21049-19823 (Counterclockwise)

Preceding gene: 150398784

Following gene: 150398782

Centisome position: 1.22

GC content: 34.39

Gene sequence:

>1227_bases
ATGGCCGAAAATTTTAGAATTATTGACGGTGGAGTTACTGCTCCAAAAGGTTTTATTGCAAACGGTCATAAAGACCGAAA
ATACGGGGTAACAATAATAGCTTCAGAAGTTGATGCGGTTTGTGCAGGTGTATTTACAACAAATAAAGTGTTTGCACATC
CAGTTTCACTTTCAAAAGAGACGTTAAAAAATAGCGATACTTTTCGTGCAATTATTGCAAATAGCGGTAATGCAAACTGC
TTTACTAAGGGCGGAATGGACGATGCAAGGGCTTTTGTAAAAAAAGCTTCAAGTTTATTGAATATTCCAGAAAGTCAGAT
TTTATCTGCGTCAACAGGCGTAATTGGTAGAAAAATGGCAATGGACATACTAAATAGGGAAGTTGAAAAGGCATATGAAA
GCCTTAAATTGGAAAGTAACAATGAAAATGCTGCAAAAGCAATAATGACCACTGATGCATTTAAAAAAACAGTTGCAGTT
GAATTTAACGTTGGAGAAAAAGTTGTTAAAATTGGAGGAATTGCAAAAGGAGCCGGTATGATTGCACCAAACATGTTACA
TGCGACTATGCTTGGATTTATTACCACAGACATTGAAATATCAAAAGAAGAACTTAAAAATTCCCTTCAAAATGCGGCTG
ATGAAAGTTTTAATAATGCAGTTGTTGACGGCGATATGAGTACAAATGATACCGTCTTTGTTTTAGCAAATGGAAAAAGT
AATGTAAATTATAGAGAATGCATTGAAGAATTTGATAAAGCACTTTTATATATTTCAACAGAACTTGCAAAAATGATAGT
TTCGGATGGAGAAGGTGCTAAAAAACTTATTGAAGCGGTTTTAAAAGGGGCTGCCACAAAAGAAGATGCAAAAAAAGCTT
CAATGTCAATTGTAAGATCGCTTCTTTTAAAAACTGCAATACATGGTGCTGATCCAAACTGGGGGCGGATTGCTGCTGCC
GTTGGCTATAGTGGTGCTGAAATGGACATGAATAATTTTGATATTATAATAAGCAGTATAACTTCTGGAAAAGAAACATA
CCTTGTAAAGTGTGGAGAACAGCTTGCTGACGAAGGAACTGCTGAATTAAAAATGGCCCAAGAAATTATGAAAGATAGTA
AAATTAGAATAACTGTTGATTTAAAAAAGGGCGAATTTAAAAATACTTCATTTGGATGCGATTTAGGTTATGAATACGTT
AGAATAAATTCAGAATATACTACATAA

Upstream 100 bases:

>100_bases
AAGTTTATTTAATAATCAAATCAAAATTACAGAGTTTACTTAAAGATATATACTTAAAGTGAATAGTTAATTATTCAAAT
AATTATGGAGATTAGAAAAT

Downstream 100 bases:

>100_bases
TTTCAATTTTAAAATGTTTAATTTTTTAAGATTTATTGTTAATTATATATTTTTTTAAGAATTTATTTATATATTTAAAT
ACATTATCCATTAAGTTTTT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAENFRIIDGGVTAPKGFIANGHKDRKYGVTIIASEVDAVCAGVFTTNKVFAHPVSLSKETLKNSDTFRAIIANSGNANC
FTKGGMDDARAFVKKASSLLNIPESQILSASTGVIGRKMAMDILNREVEKAYESLKLESNNENAAKAIMTTDAFKKTVAV
EFNVGEKVVKIGGIAKGAGMIAPNMLHATMLGFITTDIEISKEELKNSLQNAADESFNNAVVDGDMSTNDTVFVLANGKS
NVNYRECIEEFDKALLYISTELAKMIVSDGEGAKKLIEAVLKGAATKEDAKKASMSIVRSLLLKTAIHGADPNWGRIAAA
VGYSGAEMDMNNFDIIISSITSGKETYLVKCGEQLADEGTAELKMAQEIMKDSKIRITVDLKKGEFKNTSFGCDLGYEYV
RINSEYTT

Sequences:

>Translated_408_residues
MAENFRIIDGGVTAPKGFIANGHKDRKYGVTIIASEVDAVCAGVFTTNKVFAHPVSLSKETLKNSDTFRAIIANSGNANC
FTKGGMDDARAFVKKASSLLNIPESQILSASTGVIGRKMAMDILNREVEKAYESLKLESNNENAAKAIMTTDAFKKTVAV
EFNVGEKVVKIGGIAKGAGMIAPNMLHATMLGFITTDIEISKEELKNSLQNAADESFNNAVVDGDMSTNDTVFVLANGKS
NVNYRECIEEFDKALLYISTELAKMIVSDGEGAKKLIEAVLKGAATKEDAKKASMSIVRSLLLKTAIHGADPNWGRIAAA
VGYSGAEMDMNNFDIIISSITSGKETYLVKCGEQLADEGTAELKMAQEIMKDSKIRITVDLKKGEFKNTSFGCDLGYEYV
RINSEYTT
>Mature_407_residues
AENFRIIDGGVTAPKGFIANGHKDRKYGVTIIASEVDAVCAGVFTTNKVFAHPVSLSKETLKNSDTFRAIIANSGNANCF
TKGGMDDARAFVKKASSLLNIPESQILSASTGVIGRKMAMDILNREVEKAYESLKLESNNENAAKAIMTTDAFKKTVAVE
FNVGEKVVKIGGIAKGAGMIAPNMLHATMLGFITTDIEISKEELKNSLQNAADESFNNAVVDGDMSTNDTVFVLANGKSN
VNYRECIEEFDKALLYISTELAKMIVSDGEGAKKLIEAVLKGAATKEDAKKASMSIVRSLLLKTAIHGADPNWGRIAAAV
GYSGAEMDMNNFDIIISSITSGKETYLVKCGEQLADEGTAELKMAQEIMKDSKIRITVDLKKGEFKNTSFGCDLGYEYVR
INSEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=410, Percent_Identity=37.8048780487805, Blast_Score=211, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_METVS (A6UN66)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001322550.1
- ProteinModelPortal:   A6UN66
- STRING:   A6UN66
- MEROPS:   T05.001
- GeneID:   5325785
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0023
- eggNOG:   arNOG04939
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43980; Mature: 43848

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENFRIIDGGVTAPKGFIANGHKDRKYGVTIIASEVDAVCAGVFTTNKVFAHPVSLSKE
CCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCEEECCCCCCHH
TLKNSDTFRAIIANSGNANCFTKGGMDDARAFVKKASSLLNIPESQILSASTGVIGRKMA
HHCCCCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
MDILNREVEKAYESLKLESNNENAAKAIMTTDAFKKTVAVEFNVGEKVVKIGGIAKGAGM
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCEEEEECCEECCCCC
IAPNMLHATMLGFITTDIEISKEELKNSLQNAADESFNNAVVDGDMSTNDTVFVLANGKS
CCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
NVNYRECIEEFDKALLYISTELAKMIVSDGEGAKKLIEAVLKGAATKEDAKKASMSIVRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLLKTAIHGADPNWGRIAAAVGYSGAEMDMNNFDIIISSITSGKETYLVKCGEQLADEGT
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHCCCH
AELKMAQEIMKDSKIRITVDLKKGEFKNTSFGCDLGYEYVRINSEYTT
HHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
AENFRIIDGGVTAPKGFIANGHKDRKYGVTIIASEVDAVCAGVFTTNKVFAHPVSLSKE
CCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCEEECCCCCCHH
TLKNSDTFRAIIANSGNANCFTKGGMDDARAFVKKASSLLNIPESQILSASTGVIGRKMA
HHCCCCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
MDILNREVEKAYESLKLESNNENAAKAIMTTDAFKKTVAVEFNVGEKVVKIGGIAKGAGM
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCEEEEECCEECCCCC
IAPNMLHATMLGFITTDIEISKEELKNSLQNAADESFNNAVVDGDMSTNDTVFVLANGKS
CCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
NVNYRECIEEFDKALLYISTELAKMIVSDGEGAKKLIEAVLKGAATKEDAKKASMSIVRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLLKTAIHGADPNWGRIAAAVGYSGAEMDMNNFDIIISSITSGKETYLVKCGEQLADEGT
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHCCCH
AELKMAQEIMKDSKIRITVDLKKGEFKNTSFGCDLGYEYVRINSEYTT
HHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA