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The map label for this gene is cobY [H]

Identifier: 150398766

GI number: 150398766

Start: 8601

End: 9206

Strand: Reverse

Name: cobY [H]

Synonym: Mevan_0006

Alternate gene names: 150398766

Gene position: 9206-8601 (Counterclockwise)

Preceding gene: 150398772

Following gene: 150398765

Centisome position: 0.54

GC content: 27.23

Gene sequence:

>606_bases
ATGGATGTACTTATAATGGCAGGTGGAATGGGAACTCGCCTAAAAAAAAATATTGAAAAGCCACTTTTAAAAATATCTGG
TAAACCAATGATAGATTATATTATGGAAGCAGTATTAAACTCAAATATTGAAAAAATACGAATATCGGTATCTAAACATA
CTCCAAATACGAAAATATATATTGAAAATAATTATATCAATACTAAAAAATATAATCAAAGAGTGGAAATTATCCATACT
TCAGGAATAGGCTATATAAACGACCTAAATGAGTGTATAGAATATTTTAAAGAACCATTTTTAATTTTAACAAGCGATAT
CCCCACGATTAAGTCGAAAACTATTAATAGTATAATAAATGAGTATCTAATTATAAATAATAGTAATAACCCTATAGAAT
CCCTATGTGCAGTCACTTTAAAGGAAAATTATATTGGAACCCCCACTATAGATATTAAGGGGTACATTCCACTAGGCCTC
AATATAATCTCTCCAAAATATGGCGAACAAACTGAAATGCTTTATTTAATTGATGAAAAAATTGTAAATGTAAATACGTT
AATAGATAAAAACCTAGTAGAGAATATAATCAAGAAAGGTGATTAA

Upstream 100 bases:

>100_bases
TTTAGCAAGTTTACAAAATTAAAGATTTTGTAAGAATAACAGTTTTAAATATGTTTTTGGAGCTATATAAATCATACTAA
CACATTTTTTGCGTGAAAAT

Downstream 100 bases:

>100_bases
ATGAGAGTGTCCTTCAAATCATTAGCTGGAAGATCCATTGTCGGAAGTCTTGGAAGCATTATCGGAACCGTAGACGATGT
CGTAATTGATGAAAAAACAG

Product: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase

Products: NA

Alternate protein names: AdoCbi-P guanylyltransferase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MDVLIMAGGMGTRLKKNIEKPLLKISGKPMIDYIMEAVLNSNIEKIRISVSKHTPNTKIYIENNYINTKKYNQRVEIIHT
SGIGYINDLNECIEYFKEPFLILTSDIPTIKSKTINSIINEYLIINNSNNPIESLCAVTLKENYIGTPTIDIKGYIPLGL
NIISPKYGEQTEMLYLIDEKIVNVNTLIDKNLVENIIKKGD

Sequences:

>Translated_201_residues
MDVLIMAGGMGTRLKKNIEKPLLKISGKPMIDYIMEAVLNSNIEKIRISVSKHTPNTKIYIENNYINTKKYNQRVEIIHT
SGIGYINDLNECIEYFKEPFLILTSDIPTIKSKTINSIINEYLIINNSNNPIESLCAVTLKENYIGTPTIDIKGYIPLGL
NIISPKYGEQTEMLYLIDEKIVNVNTLIDKNLVENIIKKGD
>Mature_201_residues
MDVLIMAGGMGTRLKKNIEKPLLKISGKPMIDYIMEAVLNSNIEKIRISVSKHTPNTKIYIENNYINTKKYNQRVEIIHT
SGIGYINDLNECIEYFKEPFLILTSDIPTIKSKTINSIINEYLIINNSNNPIESLCAVTLKENYIGTPTIDIKGYIPLGL
NIISPKYGEQTEMLYLIDEKIVNVNTLIDKNLVENIIKKGD

Specific function: Guanylyltransferase that catalyzes the synthesis of adenosylcobinamide-GDP (AdoCbi-GDP) from adenosylcobinamide- phosphate (AdoCbi-P) and GTP. Is involved in adenosylcobalamin biosynthesis. Binds one GTP per dimer. Can not use other NTPs or GDP. Does not

COG id: COG2266

COG function: function code H; GTP:adenosylcobinamide-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005245
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.62 [H]

Molecular weight: Translated: 22809; Mature: 22809

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLIMAGGMGTRLKKNIEKPLLKISGKPMIDYIMEAVLNSNIEKIRISVSKHTPNTKIY
CEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
IENNYINTKKYNQRVEIIHTSGIGYINDLNECIEYFKEPFLILTSDIPTIKSKTINSIIN
EECCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
EYLIINNSNNPIESLCAVTLKENYIGTPTIDIKGYIPLGLNIISPKYGEQTEMLYLIDEK
CEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECEEEECCCCCCCCEEEEEECCC
IVNVNTLIDKNLVENIIKKGD
EECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVLIMAGGMGTRLKKNIEKPLLKISGKPMIDYIMEAVLNSNIEKIRISVSKHTPNTKIY
CEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
IENNYINTKKYNQRVEIIHTSGIGYINDLNECIEYFKEPFLILTSDIPTIKSKTINSIIN
EECCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
EYLIINNSNNPIESLCAVTLKENYIGTPTIDIKGYIPLGLNIISPKYGEQTEMLYLIDEK
CEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECEEEECCCCCCCCEEEEEECCC
IVNVNTLIDKNLVENIIKKGD
EECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]