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The map label for this gene is pgcA [H]

Identifier: 150395004

GI number: 150395004

Start: 2656296

End: 2658131

Strand: Direct

Name: pgcA [H]

Synonym: SaurJH1_2569

Alternate gene names: 150395004

Gene position: 2656296-2658131 (Clockwise)

Preceding gene: 150394992

Following gene: 150395005

Centisome position: 91.39

GC content: 33.33

Gene sequence:

>1836_bases
ATGATATATCACTCTTACATCTACTCCATGCATTTTCATACACATCTATTATATAATACTTGTGAAAAGTATTGTCTTGG
GGCTGTGTTTTTTTACTTTTGGGGCGTATTTCTTTATAATTCATTACATAAATGTAAGGGCTTTAGTTTTCATGTTTTAT
TAAGTCTAACTGAGATTTTGAAAGGATGTTTAGCAACAATGGATAAAGAATTATGGATAGAAAGAGCTAATGATAGTTTA
GTTAAACATTTTTATGAGCAGCAATCTGACATTGAACAGCGAGAAGGTTTTGAAAGTAAATTAACATTTGGTACTGCGGG
TATACGCGGAAAATTCGGTCTTGGTGAAGGTCGACTTAATAAGTTTACTATTGAAAAATTGGCATTAGGTTTAGCGCGTT
ATTTAAATGCCCAAACAAACAGTCCAACAATAGTCATTCATTATGATATTAGACATCTTTCAACTGAATTCGCCCAAATT
ATTGCTAATGTATTAGCAAACCATCAAATAACAGTTTATTTACCTGATACATATAAAACGACACCGGAATTATCGTTCGC
GGTTCGCAATCTTAATACTACTGCCGGCATTATGATTACAGCAAGTCATAATCCGAAAGACTATAACGGCATTAAAGTAT
ATGGTTCTGATGGCGCGCAATTATCGACTGATGCATCTGAGCTTGCAAGTCGTTATATCGAAGAAGTTGGCGATCCATTA
CAGATTGATATACCTATTTCAAAACAAAATACATCTTATATCAAACCTTTTCCGAAATCTGTAACTGATGACTATATGAA
ACACATTCAAAATATGATTGGCTATATTCCTAAATCTGATTTACAAGTTGTGTTCACTAGTTTGCATGGTACAAGTGTTC
CAATTGTACCTGAGTTATTAAAATCTTTGAATTTCAATCAATTTAATCTTGTAGATGCACAATGTAAACCTGATCCGAAT
TTTAGTTCAGTTCAAAGTGCTAATCCTGAAGATCATCACGCTTTTGATCAAGCAGTCGAACTTGCAAATAAAAGTCATGC
AGACTTATTAATATCAACTGACCCAGATGCAGATCGACTTGGTATTGCTGAACGTGATGCACATGGTCATATCACATATT
TTAATGGCAACCAAATTGGTGCGCTGTTACTTAATTATCGTATTCAACAAACGTCTCAATTACGTCACCGCTTAATGATT
CAATCTATTGTAAGTAGTGAGTTAACAAAGTCATTAGCACGCTATAATAATGTTAAATACAAAGAGGTACTGACGGGCTT
TAAATTTATTGCTCAGGAAATAAGACAACTGGATGATCATCAAAATATGATTTTCGCATTTGAAGAGAGTTACGGTTTTC
TATCAGAGCCTTTTGTACGTGATAAAGATGCCGTACAAATTGTGCCACTCATTATAAAATACGCTTCTGAGTTAAAATTA
TATGGCAAAACATTGAAAGATGAATTAGAACAGATTTATCAAACTGTTGGTAGACATGAGGATACATTATTCTCGCATAC
GCTAGAAGGATTAGAAGGTAAGAAAAAAATTGAATCAATTATGACACATTTCCGTTCAAATCCACCGCAAGAGATTCAAG
GACTGAAAGTGAAAGCAATTGAAGATTATTTAACTAGCGAGGTTTATCATTTGGATAAAGATACAACGTCACAGATTAAT
TCTTCTAAATCAAATGTTATTCGTGTCTTATTTGACGAAGGATTTATCGCTTTACGTCCTTCTGGTACTGAACCTAAAAT
TAAATTATATGTGTCGTTAAAATGTCCGGATTTTGATGATGTAGCTCAAAAAATTAATGCGATGATTTTTAGCTAA

Upstream 100 bases:

>100_bases
CTCACCCTTCAATTTAAAATCATCTTAATTGTTATTCTATCAAAAATTACAAAACTATATATAAATCAATATTAAAAATT
AATATTTTACAATTTCCTGC

Downstream 100 bases:

>100_bases
TTAAAAATTTTATACATCGAAATATTACATTTCATTTTATACTTATCAGCCCTTTTGAAACTAGAATCCTTATGTTTTCG
CGTTTTGAAGGGGCTAATTT

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MIYHSYIYSMHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSL
VKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQI
IANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPL
QIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPN
FSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMI
QSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKL
YGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQIN
SSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS

Sequences:

>Translated_611_residues
MIYHSYIYSMHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSL
VKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQI
IANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPL
QIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPN
FSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMI
QSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKL
YGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQIN
SSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS
>Mature_611_residues
MIYHSYIYSMHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSL
VKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQI
IANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPL
QIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPN
FSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMI
QSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKL
YGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQIN
SSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also use

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=583, Percent_Identity=32.590051457976, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI31377548, Length=549, Percent_Identity=32.2404371584699, Blast_Score=229, Evalue=4e-60,
Organism=Escherichia coli, GI1789566, Length=302, Percent_Identity=28.476821192053, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788361, Length=264, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=560, Percent_Identity=29.8214285714286, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71993878, Length=321, Percent_Identity=30.8411214953271, Blast_Score=132, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323934, Length=552, Percent_Identity=27.7173913043478, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI20129809, Length=563, Percent_Identity=29.4849023090586, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24651977, Length=537, Percent_Identity=28.4916201117318, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24653722, Length=533, Percent_Identity=29.0806754221388, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 69470; Mature: 69470

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYHSYIYSMHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEIL
CEEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCH
KFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKT
HHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
TPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPL
CCCHHHHEECCCCCEEEEEEECCCCCCCCCEEEECCCCCEECCCHHHHHHHHHHHCCCCE
QIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCHHHHHH
KSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRL
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHC
GIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKY
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHH
EDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDD
HHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEECCEEEECCCCCCCEEEEEEEEECCCHHH
VAQKINAMIFS
HHHHHHHHHCC
>Mature Secondary Structure
MIYHSYIYSMHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEIL
CEEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCH
KFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKT
HHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
TPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPL
CCCHHHHEECCCCCEEEEEEECCCCCCCCCEEEECCCCCEECCCHHHHHHHHHHHCCCCE
QIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCHHHHHH
KSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRL
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHC
GIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKY
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHH
EDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDD
HHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEECCEEEECCCCCCCEEEEEEEEECCCHHH
VAQKINAMIFS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA